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| 1 | 剖腹产疤痕子宫内膜异位症显示文摘子宫内膜异位症是一常见而又疑难的疾病,尽管一个世纪以前已有描述,但至今仍是临床医生和研究者继续争论的问题。剖腹产腹壁疤痕子宫内膜异位症不多见,文献报告更少。本文报告近5年内证实的5例,并收集1956年以来的文献19篇,共90例疤痕子宫内膜异位症,对其诊断和治疗进行讨论。所收集的疤痕子宫内膜异位症的临床特征类似。年龄范围在21~40岁,疤痕中均有周期性触痛包块。 | Wolf GC Singh KB 陈韵仙 | 1990 | 国外医学(妇产科学分册)1990，17，2： | 82 |
| 2 | Telomerase catalytic subunit homologs from fission yeast and human显示文摘 | Nakamura TM Morin GB Chapman KB | | 0，，： | 10 |
| 3 | Enhancement of glioblastoma radioresponse by a selective COX-2 inhibitor celecoxib: inhibition of tumor angiogenesis with extensive tumor necrosis显示文摘 | Kang KB Wang TT Woon CT Cheah ES Moore XL Zhu C Wong MC | 2007 | 中国神经肿瘤杂志2007，5，2： | 8 |
| 4 | 木豆杂种优势利用研究进展显示文摘自1974年发现木豆雄性不育株以来,国际上不断对木豆核雄性不育(GMS)和核质互作雄性不育(CGMS)基因及其种质资源进行研究和挖掘,最终实现了木豆杂种优势的成功利用。本文系统总结了过去30多年来,国际上木豆杂种优势机理、表现及授粉方式等基础研究,GMS、CGMS不育系及其配套制种体系研究,杂种优势强度研究,以及木豆杂交种生产技术研究进展。提出了木豆杂种优势利用的具体研究方向和展望。 | 宗绪晓 KB Saxena | 2006 | 作物杂志2006，，5： | 6 |
| 5 | 浓缩生长因子(CGF)对Masquelet技术中诱导膜质量的影响--以兔为对象的实验研究显示文摘目的:本研究的目的是为了测试Masquelet技术中添加浓缩生长因子(CGF)是否有助于围绕聚甲基丙烯酸甲酯(PMMA)形成的膜的质量.在早期和晚期的兔模型中研究Masquelet技术中的炎症、增殖和血管形成。材料与方法:在桡骨骨干处形成15mm的严重骨缺损,保留关节处3cm的完整骨。 | Yιlmaz O ?zmeri? A Alemdaroglu KB 赵泽亮 | 2018 | 中国口腔颌面外科杂志2018，16，4： | 6 |
| 6 | Promoter polymorphism of transforming growth factor-β1 gene and ulcerative colitis显示文摘AIM: To elucidate the possible difference in two promoter polymorphisms of the transforming growth factor-β1 (TGF-β1) gene (-800G > A, -509C > T) between ulcerative colitis (UC) patients and normal subjects.METHODS: A total of 155 patients with established ulcerative colitis and 139 normal subjects were selected as controls. Two single nucleotide polymorphisms within the promoter region of TGF-β1 gene (-509C > T and -800G > A) were genotyped using PCR-RFLP. RESULTS: There was a statistically significant difference in genotype and allele frequency distributions between UC patients and controls for the -800G > A polymorphism of the TGF-β1 gene (P < 0.05). The frequency of the TGF-β1 gene polymorphism at position -800 showed that the AA genotype and the allele A frequencies significantly differed between the patients and healthy controls (P < 0.05). At position -509, there was no statically significant difference in genotype and allele frequency between the patients and control subjects.CONCLUSION: The results of our study indicate that there is a significant difference in both allele and genotype frequency at position -800G > A of TGF-β1 gene promoter between Iranian patients with UC and normal subjects. | B Tamizifar KB Lankarani S Naeimi M Rismankar Zadeh A Taghavi A Ghaderi | 2008 | World Journal of Gastroenterology2008，14，2： | 4 |
| 7 | Cultivation-dependent and cultivation-independent characterization of the microbial community in acid mine drainage associated with acidic Pb/ Zn mine tailings at Lechang, Guangdong, China显示文摘 | Tan GL Shu WS Hallberg KB Li F Lan CY Huang LN | 2007 | 中国生物学文摘2007，21，7： | 3 |
| 8 | 重组脊髓灰质炎病毒用于治疗复发胶质母细胞瘤(英文)显示文摘Background The prognosis of patients with recurrent World Health Organization(WHO)grade IV malignant glioma is dismal,and there is currently no effective therapy.We conducted a dose-finding and toxicity study in this population of patients,evaluating convection-enhanced,intratumoral delivery of the recombinant nonpathogenic polio-rhinovirus chimera(PVSRIPO).PVSRIPO recognizes the poliovirus receptor CD155,which is widely expressed in neoplastic cells of solid tumors and in major components of the tumor microenvironment.Methods We enrolled consecutive adult patients who had recurrent supratentorial WHO grade IV malignant glioma,confirmed on histopathological testing,with measurable disease(contrast-enhancing tumor of≥1 cm and≤5.5 cm in the greatest dimension).The study evaluated seven doses,ranging between 107 and 1010 50%tissue-culture infectious doses(TCID50),first in a dose-escalation phase and then in a dose-expansion phase.Results From May 2012 through May 2017,a total of 61 patients were enrolled and received a dose of PVSRIPO.Dose level-1(5.0×107TCID50)was identified as the phase 2 dose.One dose-limiting toxic effect was observed;a patient in whom dose level 5(1010TCID50)was administered had a grade 4 intracranial hemorrhage immediately after the catheter was removed.To mitigate locoregional inflammation of the infused tumor with prolonged glucocorticoid use,dose level 5 was deescalated to reach the phase 2 dose.In the dose-expansion phase,19%of the patients had a PVSRIPO-related adverse event of grade 3 or higher.Overall survival among the patients who received PVSRIPO reached a plateau of 21%(95%confidence interval,11 to 33)at 24 months that was sustained at 36 months.Conclusions Intratumoral infusion of PVSRIPO in patients with recurrent WHO grade IV malignant glioma confirmed the absence of neurovirulent potential.The survival rate among patients who receivedPVSRIPO immunotherapy was higher at 24 and 36 months than the rate among historical controls. | Desjardins A Gromeier M Herndon JE 2nd Beaubier N Bolognesi DP Friedman AH Friedman HS McSherry F Muscat AM Nair S Peters KB Randazzo D Sampson JH Vlahovic G Harrison WT McLendon RE Ashley D Bigner DD | 2018 | 中华神经外科疾病研究杂志2018，17，4： | 2 |
| 9 | Telomerase catalytic subunit homologs from fission yeast and human显示文摘 | Nakamura TM Morin GB Chapman KB | 1997 | Science1997，277，5328： | 2 |
| 10 | 眼部用药对老年人的全身影响显示文摘老年人使用眼药的情况是很普遍的,这些药物可能具有严重的全身影响,特别是在老年病人。这在医源性疾病的鉴别诊断中应予以考虑。文献报道的这个问题并非仅限于老龄人群,尽管大多数病人属于老年。眼药滴入球结膜囊中,除少量流出或吞下外,大部分均经由结膜毛细血管、鼻粘膜及咽部直接进入血液循环,其吸收量之大可足以产生副作用。由于老年人常常使用多种药物,因而与其他药物产生药物相互作用的可能性亦是存在的。 | Anand KB 夏德瑂 | 1989 | 国外医学(内科学分册)1989，16，8： | 2 |
| 11 | Biomechanical characteristics of the human esophagus显示文摘 | Orvar KB Gregersen H Christensen J | 1993 | Dig Dis Sci1993，38，2： | 2 |
| 12 | 生理性线粒体破碎是心脏适应能量需求增加的正常现象显示文摘线粒体在心脏中起着双重作用:负责满足能量需求和调节细胞凋亡。通常认为,线粒体的分裂和碎裂是病理性应激(如缺血)的结果,是线粒体质量差的指标,并导致线粒体自噬和细胞死亡。然而,最近的研究表明,抑制裂变也导致线粒体功能减弱和心脏损害,说明裂变对维持心脏和线粒体生物能量平衡十分重要。 | 刘莉 叶鹏 Coronado M Fajardo G Nguyen K Zhao M Kooiker KB Jung G Hu DQ Reddy S Sandoval E Stotland A Gottlieb RA Bernstein D | 2018 | 中华高血压杂志2018，26，1： | 2 |
| 13 | Small arterial-portal venous shunts:a cause of pseudolesions at hepatic imaging显示文摘 | Yu JS Kim KW Sung KB | 1997 | Radiology1997，2003，： | 1 |
| 14 | Accumulation of ultrasmall superparamagnetic particles of iron oxide in human atherosclerotic plaques can be detected by in vivo magnetic resonance imaging显示文摘 | Kooi ME Cappendljk VC Cleutjens KB | 2003 | Circulation2003，107，19： | 1 |
| 15 | American association of clinical endocrinologists medical guidelines for clinical practice for the evaluation and treatment of hyperthyroidism and hypothyroid dysfunction 显示文摘 | Ladenson PW Singer AP Ain KB | 2000 | Arch intern Med2000，160，： | 1 |
| 16 | Transverse displacement of the proximal segment after bilateral sagittal osteotomy 显示文摘 | Becktor JP Rebellato J Becktor KB | 2002 | Oral Maxillofac Surg2002，60，4： | 1 |
| 17 | Mechanical properties of a gelidium corneum edible film containing Catechin and its application in sausages 显示文摘 | Ku KJ Hong YH Song KB | 2008 | Journal of Food Science2008，73，3： | 1 |
| 18 | Obesity and the metabolic syndrome 显示文摘 | Keller KB Lemberg C | 2003 | Am J Crit Care2003，12，2： | 1 |
| 19 | Increased plasma endothelin - 1 in the early hours of acute myocardial infarction显示文摘 | Sterwart DJ Kubac G Costello KB | 1991 | J Am Coll Cardiol1991，18，： | 1 |
| 20 | The adequacy of laboratory moniloring in patients treated with spironolactone for congestive heart failure显示文摘 | Shah KB Rao K Sawyer R | 2005 | J Am Coll Cardiol2005，46，5： | 1 |
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