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| 1 | 竹材力学性能及其在土木工程中应用的研究进展显示文摘近年来,建筑业的可持续发展引起了越来越广泛的关注。竹材具有资源丰富、成材快、材性优良等特点,是一种优质的绿色生态建筑材料。首先对竹材性能的研究进行了调研,分别总结了在测定方法、力学性能变异性和力学模型方面最新的研究成果以及尚待解决的问题;其次,对原竹在土木工程中的研究及应用进行了总结,指出了原竹在工程应用中需要解决的关键技术问题;随后,对工程竹的研究现状进行分析,提出了提高其力学性能和生产工艺的技术途径。本文将为竹材性能和应用研究提供参考,有利于推广竹材这一'绿色生态建筑材料'在土木工程中的广泛应用。 | 陈溪 许清风 Kent A. Harries | 2015 | 结构工程师2015，31，6： | 27 |
| 2 | Stochastic structural model of rock and soil aggregates by continuum-based discrete element method显示文摘This paper first presents a stochastic structural model to describe the random geometrical features of rock and soil aggregates. The stochastic structural model uses mixture ratio, rock size and rock shape to construct the microstructures of aggregates, and introduces two types of structural elements (block element and jointed element) and three types of material elements (rock element, soil element, and weaker jointed element) for this microstructure. Then, continuum-based discrete element method is used to study the deformation and failure mechanism of rock and soil aggregate through a series of loading tests. It is found that the stress-strain curve of rock and soil aggregates is nonlinear, and the failure is usually initialized from weaker jointed elements. Finally, some factors such as mixture ratio, rock size and rock shape are studied in detail. The numerical results are in good agreement with in situ test. Therefore, current model is effective for simulating the mechanical behaviors of rock and soil aggregates. | WANG Yuannian1, ZHAO Manhong1, LI Shihai1 & J.G. Wang21. Institute of Mechanics, Chinese Academy of Sciences, Beijing 100080, China 2. Tropical Marine Science Institute, National University of Singapore, 10 Kent Ridge Crescent, Singapore 119260 | 2005 | Science China(Technological Sciences)2005，48，z1： | 21 |
| 3 | A different spectrum of DMD gene mutations in local Chinese patients with Duchenne/Becker muscular dystrophy显示文摘背景 Duchenne 肌肉发达的营养障碍(DMD ) 和贝克尔肌肉发达的营养障碍(BMD ) 是 X 连接后退的、突变而产生之遗传的混乱。这研究被进行与 Duchenne 或贝克尔在香港中国病人调查 DMD 基因变化的光谱,并且学习遗传型显型肌肉发达的营养障碍(DMD/BMD ) 关联。67 个病人的方法 Aretrospective 评论。结果 23 (34.3%) 病人们在删除上有前;而 5 (7.5%) 病人们在复制上有前。23 (34.3%) 病人们有小变化,包括 17 个点变化和 6 小插入或删除。没有关联在变化和肌肉显型或智力迟钝的类型之间被发现。显著地,更少母亲的搬运人在删除上与前在病人被发现,并且积极家庭历史在有小变化的那些是更普通的。DMD 显型是显著地不在有在 5'' 热点的 exondeletions/duplications 的病人普通,而与智力迟钝联系的所有 4 个小变化位于 3'' ,基因结束。结论在本地中国病人的 DMD exondeletions 的百分比比显著地低通常引用了 60% 。Thisindicated 在到删除上的 DMD 前的倾向的种族或地区性的差别。 | Ivan Fai-man Lo Kent Keung-san Lai Tony Ming-for Tong Stephen Tak-sum Lam | 2006 | Chinese Medical Journal2006，，13： | 21 |
| 4 | 对骨折内固定术后早期感染者保留内固定物的策略显示文摘背景:开放复位内固定术后,在内固定物存在的情况下治疗伤口深部感染极为棘手,关于治疗方案的使用,文献报道甚少。本研究旨在探讨骨折内固定术后6周内发生感染后保留内固定物直至骨性愈合的可能性。方法:通过回顾3个I级创伤中心以往的病历和创伤登记表,共纳入121例新鲜骨折患者,这些患者术中细菌培养均为阳性,内固定术后6周内共123处创口发生感染。统计保留内固定物并获骨折愈合者的比率,评价预测其治疗成败的指标。结果:86例患者(87处骨折;71%)经手术清创、保留内固定物和敏感抗生素治疗获得骨折愈合。治疗失败的有关因素包括开放性骨折(p=0.03)和髓内钉固定(p=0.01)。其他非明显相关但有相关倾向的变量包括吸烟、假单胞菌感染以及累及股骨、胫骨、踝部或足部的骨折。结论:骨折内固定术后深部感染者可通过手术清创、敏感抗生素治疗及保留内固定物成功获得骨折愈合。这些结果可通过基于危险基因、特定菌种和有关的内固定种类对患者进行选择而获得改善。 | Marschall Berkes, MD William T. Obremskey, MD MPH, Brian Scannell, MD J. Kent Ellington, MD Robert A. Hymes, MD Michael Bosse, MD, and the Southeast Fracture Consortium 黄哲元(译) 丁真奇(译) | 2010 | 中华骨科杂志2010，30，9： | 21 |
| 5 | An assessment of coal pillar system stability criteria based on a mechanistic evaluation of the interaction between coal pillars and the overburden显示文摘Coal pillar design has historically assigned a factor of safety(Fo S) or stability factor(SF) according to their estimated strength and the assumed overburden load acting on them. Acceptable Fo S values have been assigned based on past mining experience or a statistical link between Fo S and probability of failure(Po F). Pillar width-to-height(w/h) ratio has long been established as having a material influence on both pillar strength and its potential failure mode. However, there has been significant disagreement on using both factor of safety(Fo S) and w/h as part of pillar system stability criterion, as compared to using Fo S in isolation. This paper will argue that there are valid technical reasons to bring w/h ratio into system stability criteria(other than its influence on pillar strength), as it is related to the post-failure stiffness of the pillar, as measured in situ, and its interaction with overburden stiffness. When overburden stiffness is also brought into pillar system stability considerations, two issues emerge. The first is the width-todepth(W/D) ratio of the panel and whether it is sub-critical or super-critical from a surface subsidence perspective. The second relates to a re-evaluation of pillar Fo S based on whether the pillar is in an elastic or non-elastic(i.e., post-yield) state in its as-designed condition, as this is relevant to maintaining overburden stiffness at the highest possible level. The significance of the model is the potential to maximise both reserve recovery and mining efficiencies without any discernible increase in geotechnical risk, particularly in thick seams and higher depth of cover mining situations. At a time when mining economics are, at best, marginal, removing potentially unnecessary design conservatism is of interest to all mine operators and is an important topic for discussion amongst the geotechnical community. | Reed Guy Mctyer Kent Frith Russell | 2017 | International Journal of Mining Science and Technology2017，27，1： | 21 |
| 6 | A planet in transition:The onset of plate tectonics on Earth between 3 and 2 Ga?显示文摘Many geological and geochemical changes are recorded on Earth between 3 and 2 Ga.Among the more important of these are the following:(1)increasing proportion of basalts with'arc-like'mantle sources;(2)an increasing abundance of basalts derived from enriched(EM)and depleted(DM)mantle sources;(3)onset of a Great Thermal Divergence in the mantle;(4)a decrease in degree of melting of the mantle;(5)beginning of large lateral plate motions;(6)appearance of eclogite inclusions in diamonds;(7)appearance and rapid increase in frequency of collisional orogens;(8)rapid increase in the production rate of continental crust as recorded by zircon age peaks;(9)appearance of ophiolites in the geologic record,and(10)appearance of global LIP(large igneous province)events some of which correlate with global zircon age peaks.All of these changes may be tied directly or indirectly to cooling of Earth's mantle and corresponding changes in convective style and the strength of the lithosphere,and they may record the gradual onset and propagation of plate tectonics around the planet.To further understand the changes that occurred between 3 and 2 Ga,it is necessary to compare rocks,rock associations,tectonics and geochemistry during and between zircon age peaks.Geochemistry of peak and inter-peak basalts and TTGs needs to be evaluated in terms of geodynamic models that predict the existence of an episodic thermal regime between stagnant-lid and plate tectonic regimes in early planetary evolution. | Kent C.Condie | 2018 | Geoscience Frontiers2018，9，1： | 18 |
| 7 | The Ozone Component of Global Change:Potential Effects on Agricultural and Horticultural Plant Yield,Product Quality and Interactions with Invasive Species显示文摘The productivity,product quality and competitive ability of important agricultural and horticultural plants in many regions of the world may be adversely affected by current and anticipated concentrations of ground-level ozone(O3).Exposure to elevated O3 typically results in suppressed photosynthesis,accelerated senescence,decreased growth and lower yields.Various approaches used to evaluate O3 effects generally concur that current yield losses range from 5% to 15% among sensitive plants.There is,how-ever,considerable genetic variability in plant responses to O3.To illustrate this,we show that ambient O3 concentrations in the eastern United States cause substantially different levels of damage to otherwise similar snap bean cultivars.Largely undesirable effects of O3 can also occur in seed and fruit chemistry as well as in forage nutritive value,with consequences for animal production.Ozone may alter herbicide efficacy and foster estab-lishment of some invasive species.We conclude that current and projected levels of O3 in many regions worldwide are toxic to sensitive plants of agricultural and horticultural significance.Plant breeding that incorporates O3 sensitivity into selection strategies will be increasingly necessary to achieve sustainable production with changing atmospheric composition,while reductions in O3 precursor emissions will likely benefit world food pro-duction and reduce atmospheric concentrations of an important greenhouse gas. | Fitzgerald Booker Russell Muntifering Margaret McGrath Kent Burkey Dennis Decoteau Edwin Fiscus William Manning Sagar Krupa Arthur Chappelka David Grantz | 2009 | Journal of Integrative Plant Biology2009，51，4： | 18 |
| 8 | Radioembolization for the treatment of unresectable hepatocellular carcinoma:A clinical review显示文摘Hepatocellular carcinoma(HCC)is the sixth most common cancer in the world.The majority of patients with HCC present with unresectable disease.These patients have historically had limited treatment options secondary to HCC demonstrating chemoresistance to the currently available systemic therapies.Additionally, normal liver parenchyma has shown intolerance to tumoricidal radiation doses,limiting the use of external beam radiation.Because of these limitations,novel percutaneous liver-directed therapies have emerged. The targeted infusion of radioactive microspheres (radioembolization)represents one such therapy. Radioembolization is a minimally invasive transcatheter therapy through which radioactive microspheres are infused into the hepatic arteries that supply tumor. Once infused,these microspheres traverse the hepatic vascular plexus and selectively implant within the tumor arterioles.Embedded within the arterioles, the 90Y impregnated microspheres emit high energy and low penetrating radiation doses selectively to the tumor.Radioembolization has recently shown promise for the treatment of patients with unresectable HCC. The objective of this review article is to highlight twocurrently available radioembolic devices(90Y,188Rh)and provide the reader with a recent review of the literature. | Saad M Ibrahim Robert J Lewandowski Kent T Sato Vanessa L Gates Laura Kulik Mary F Mulcahy Robert K Ryu Reed A Omary Riad Salem | 2008 | World Journal of Gastroenterology2008，14，11： | 14 |
| 9 | 钢中镁铝尖晶石夹杂物研究现状及发展显示文摘钢中MgAl2O4夹杂物熔点高不变形,对高级别钢种质量危害大,是近几年洁净钢领域研究的热点。阐述了MgAl2O4夹杂物产生的背景,总结了钢中MgAl2O4夹杂物研究现状,提出需要对MgAl2O4夹杂物向低熔点四元复合氧化物夹杂转变的动力学作进一步研究。 | 杨树峰 李京社 朱立光 陈永峰 张立峰 Kent Peaslee | 2010 | 炼钢2010，26，1： | 14 |
| 10 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 11 | A great thermal divergence in the mantle beginning 2.5 Ga:Geochemical constraints from greenstone basalts and komatiites显示文摘Greenstone basalts and komatiites provide a means to track both mantle composition and magma generation temperature with time.Four types of mantle are characterized from incompatible element distributions in basalts and komatiites:depleted,hydrated,enriched and mantle from which komatiites are derived.Our most important observation is the recognition for the first time of what we refer to as a Great Thermal Divergence within the mantle beginning near the end of the Archean,which we ascribe to thermal and convective evolution.Prior to 2.5 Ga,depleted and enriched mantle have indistinguishable thermal histories,whereas at 2.5-2.0 Ga a divergence in mantle magma generation temperature begins between these two types of mantle.Major and incompatible element distributions and calculated magma generation temperatures suggest that Archean enriched mantle did not come from mantle plumes,but was part of an undifferentiated or well-mixed mantle similar in composition to calculated primitive mantle.During this time,however,high-temperature mantle plumes from dominantly depleted sources gave rise to komatiites and associated basalts.Recycling of oceanic crust into the deep mantle after the Archean may have contributed to enrichment of Ti,Al,Ca and Na in basalts derived from enriched mantle sources.After 2.5 Ga,increases in Mg~# in basalts from depleted mantle and decreases in Fe and Mn reflect some combination of growing depletion and cooling of depleted mantle with time.A delay in cooling of depleted mantle until after the Archean probably reflects a combination of greater radiogenic heat sources in the Archean mantle and the propagation of plate tectonics after 3 Ga. | Kent C.Condie Richard C.Aster Jeroen van Hunen | 2016 | Geoscience Frontiers2016，7，4： | 11 |
| 12 | Medaka fish stem cells and their applications显示文摘Stem cells are present in developing embryos and adult tissues of multicellular organisms. Owing to their unique features, stem cells provide excellent opportunities for experimental analyses of basic developmental processes such as pluripotency control and cell fate decision and for regenerative medicine by stem cell-based therapy. Stem cell cultures have been best studied in 3 vertebrate organisms. These are the mouse, human and a small laboratory fish called medaka. Specifically, medaka has given rise to the first embryonic stem (ES) cells besides the mouse, the first adult testis-derived male stem cells spermatogonia capable of test-tube sperm production, and most recently, even haploid ES cells capable of producing Holly, a semi-cloned fertile female medaka from a mosaic oocyte created by microinjecting a haploid ES cell nucleus directly into a normal oocyte. These breakthroughs make medaka a favoring vertebrate model for stem cell research, the topic of this review. | YI MeiSheng1, HONG Ni1, LI ZhenDong1, YAN Yan1,2, WANG DanKe1, ZHAO HaoBin1,3 & HONG YunHan1,4* 1Department of Biological Sciences, National University of Singapore, 10 Kent Ridge Crescent, Singapore 119260, Singapore 2Division of Bioengineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore 637457, Singapore 3Hubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Huazhong Normal University, Wuhan 430079, China 4State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China | 2010 | Science China(Life Sciences)2010，53，4： | 10 |
| 13 | An epigenomic approach to therapy for tamoxifen-resistant breast cancer显示文摘Tamoxifen 是为雌激素受体 alpha 的前线治疗(ERα) 在绝经前的女人的积极的胸肿瘤。然而,到 tamoxifen 的抵抗发生在许多病人。嗯仍然与获得的 tamoxifen 抵抗在乳癌房间的生长起一个关键作用,建议那 ERα为治疗仍然是一个有效目标 tamoxifen 抵抗(Tam-R ) 乳癌。以识别 ERα 的新奇管理者;发信号,通过对 histone 甲基修饰词的一幅小规模的 siRNA 屏幕,我们发现了 WHSC1, histone H3K36 methyltransferase, ERα 的一个积极管理者;在乳癌房间发信号。我们证明 WHSC1 被招募到 ERα由 BET 蛋白质 BRD3/4 的基因,并且便于 ERα基因表示。小分子的赌注蛋白质禁止者 JQ1 potently 压制了经典 ERα发信号的小径和在文化的 Tam-R 乳癌房间的生长。用一个 Tam-R 乳癌异种皮移植老鼠模型,我们与 JQ1 和 ER degrader fulvestrant 由 JQ1 和联合治疗的强壮的长持续的效果在 vivo 反胸癌症活动示威了。一起拿,我们提供 epigenomic 蛋白质 BRD3/4 和 WHSC1 是雌激素受体发信号的必要管理者并且是为 Tam-R 乳癌的治疗的新奇治疗学的目标的证据。 | Qin Feng Zheng Zhang Martin J Shea Chad J Creighton Cristian Coarfa Susan G Hilsenbeck Rainer Lanz Bin He Lei Wang Xiaoyong Fu Agostina Nardone Yongcheng Song James Bradner Nicholas Mitsiades Constantine S Mitsiades C Kent Osborne Rachel Schiff Bert W O'Malley | 2014 | Cell Research2014，24，7： | 10 |
| 14 | Prevention and management of hepatitis B virus reactivation in patients with hematological malignancies treated with anticancer therapy显示文摘Hepatitis due to hepatitis B virus(HBV) reactivation can be severe and potentially fatal, but is preventable. HBV reactivation is most commonly reported in patients receiving cancer chemotherapy, especially rituximabcontaining therapy for hematological malignancies and those receiving stem cell transplantation. All patients with hematological malignancies receiving anticancer therapy should be screened for active or resolved HBV infection by blood tests for hepatitis B surface antigen(HBs Ag) and antibody to hepatitis B core antigen(antiHBc). Patients found to be positive for HBs Ag should be given prophylactic antiviral therapy to prevent HBV reactivation. For patients with resolved HBV infection, no standard strategy has yet been established to prevent HBV reactivation. There are usually two options. One is pre-emptive therapy guided by serial HBV DNA monitoring, whereby antiviral therapy is given as soon as HBV DNA becomes detectable. However, there is little evidence regarding the optimal interval and period of monitoring. An alternative approach is prophylactic antiviral therapy, especially for patients receiving highrisk therapy such as rituximab, newer generation of anti-CD20 monoclonal antibody, obinutuzumab or hematopoietic stem cell transplantation. This strategy may effectively prevent HBV reactivation and avoid the inconvenience of repeated HBV DNA monitoring. Entecavir or tenofovir are preferred over lamivudine as prophylactic therapy. Although there is no well-defined guideline on the optimal duration of prophylactic therapy, there is growing evidence to recommend continuing prophylactic antiviral therapy for at least 12 mo after cessation of chemotherapy, and even longer for those who receive rituximab or who had high serum HBV DNA levels before the start of immunosuppressive therapy. Many novel agents have recently become available for the treatment of hematological malignancies, and these agents may be associated with HBV reactivation. Although there is currently limited evidence to guide the optimal preventive measures, we recommend antiviral prophylaxis in HBs Ag-positive patients receiving novel treatments, especially the Bruton tyrosine kinase inhibitors and the phosphatidylinositol 3-kinase inhibitors, which are B-cell receptor signaling modulators and reduce proliferation of malignant B-cells. Further studies are needed to clarify the risk of HBV reactivation with these agents and the best prophylactic strategy in the era of targeted therapy for hematological malignancies. | Man Fai Law Rita Ho Carmen KM Cheung Lydia HP Tam Karen Ma Kent CY So Bonaventure Ip Jacqueline So Jennifer Lai Joyce Ng Tommy HC Tam | 2016 | World Journal of Gastroenterology2016，22，28： | 10 |
| 15 | 从加拿大医学生外科实习谈加强对医学生临床实践能力的培养显示文摘医学教育国际化教学改革新形势下,如何加强医学生临床实践能力的培养是我们亟待思考和解决的问题。本文介绍了加拿大麦吉尔大学医学生外科实习情况,并与国内医学生临床实习情况的异同进行了比较,对加强医学生临床实践能力培养的新举措进行了探讨。 | 袁时芳 Kent Mackenzie | 2011 | 西北医学教育2011，19，3： | 9 |
| 16 | 影响丙烯酸类紫外光固化涂料消光的参数显示文摘在紫外光固化涂料中,要得到好的0消光效果,涂料的配方和消光剂都很重要。本文叙述了影响丙烯酸类紫外光固化涂料消光性能的主要参数,包括消光剂的孔体积、粒径、表面处理,以及光引发剂/光引发协同剂的性能对消光的重要影响。 | D.J . Kent et al | 1996 | 涂料工业1996，26，6： | 7 |
| 17 | A THIRD-ORDER BOUSSINESQ MODEL APPLIED TO NONLINEAR EVOLUTION OF SHALLOW-WATER WAVES显示文摘The conventional Boussinesq model is extended to the third order in dispersion and nonlinearity. The new equations are shown to possess better linear dispersion characteristics. For the evolution of periodic waves over a constant depth, the computed wave envelops are spatially aperiodic and skew. The model is then applied to the study of wave focusing by a topographical lens and the results are compared with Whalin′s (1971) experimental data as well as some previous results from the conventional Boussinesq model. Encouragingly, improved agreement with Whalin′s experimental data is found. [WT5”HZ] | Zhang Ying long CCM MINDEF, Department of Mech. and Prod. Eng., National University of Singapore, 10 Kent Ridge Crescent, Singapore 119260 Zhu Song ping Department of Mathematics, the University of Wollongong, Wollongong, NSW 2522, Australia | 2000 | Journal of Hydrodynamics2000，12，2： | 7 |
| 18 | Motility-based label-free detection of parasites in bodily fluids using holographic speckle analysis and deep learning显示文摘Parasitic infections constitute a major global public health issue.Existing screening methods that are based on manual microscopic examination often struggle to provide sufficient volumetric throughput and sensitivity to facilitate early diagnosis.Here,we demonstrate a motility-based label-free computational imaging platform to rapidly detect motile parasites in optically dense bodily fluids by utilizing the locomotion of the parasites as a specific biomarker and endogenous contrast mechanism.Based on this principle,a cost-effective and mobile instrument,which rapidly screens~3.2 mL of fluid sample in three dimensions,was built to automatically detect and count motile microorganisms using their holographic time-lapse speckle patterns.We demonstrate the capabilities of our platform by detecting trypanosomes,which are motile protozoan parasites,with various species that cause deadly diseases affecting millions of people worldwide.Using a holographic speckle analysis algorithm combined with deep learningbased classification,we demonstrate sensitive and label-free detection of trypanosomes within spiked whole blood and artificial cerebrospinal fluid(CSF)samples,achieving a limit of detection of ten trypanosomes per mL of whole blood(~five-fold better than the current state-of-the-art parasitological method)and three trypanosomes per mL of CSF.We further demonstrate that this platform can be applied to detect other motile parasites by imaging Trichomonas vaginalis,the causative agent of trichomoniasis,which affects 275 million people worldwide.With its costeffective,portable design and rapid screening time,this unique platform has the potential to be applied for sensitive and timely diagnosis of neglected tropical diseases caused by motile parasites and other parasitic infections in resource-limited regions. | Yibo Zhang Hatice Ceylan Koydemir Michelle M.Shimogawa Sener Yalcin Alexander Guziak Tairan Liu Ilker Oguz Yujia Huang Bijie Bai Yilin Luo Yi Luo Zhensong Wei Hongda Wang Vittorio Bianco Bohan Zhang Rohan Nadkarni Kent Hill Aydogan Ozcan | 2018 | Light(Science & Applications)2018，7，1： | 6 |
| 19 | Behavior of MgO·Al_2O_3 Based Inclusions in Alloy Steel During Refining Process显示文摘The transformation of MgO·Al2O3 based inclusions in alloy steel during refining has been studied by industrial trials.Besides Factsage software is used to study the formation and modification of spinel inclusions in alloy steel using calcium treatment during refining process.The results show that the transformation sequence of inclusions is:MgO·Al2O3→CaO-Al2O3-MgO complex inclusions→MgO·Al2O3,and under present experimental condition,in order to avoid forming MgO·Al2O3 inclusions the content of dissolved Ca in the molten steel has to reach 1×10-6.Also the results show that when more calcium was added to molten steel,the content of Al2O3 and MgO will be lower.Besides,increasing the content of CaO in the inclusions will increase even if the content of SiO2 changes little. | YANG Shu-feng LI Jing-she ZHANG Li-feng Kent Peaslee WANG Zai-fei | 2010 | Journal of Iron and Steel Research(International)2010，17，7： | 5 |
| 20 | 卒中治疗专业学术圆桌会议临床前推荐更新版显示文摘首份卒中治疗专业学术圆桌会议(Stroke Yherapy Academic Industry Roundtable,STAIR)推荐于1999年出版,旨在提高潜在的急性卒中治疗方法的临床前研究质量。虽然这些推荐意见被认为是合理的,但并未得到严格的遵循和验证。为了更好地向临床转化,有关候选急性卒中疗法的临床前试验的质量和广度已取得实质性进展。更新后的STAIR临床前推荐进一步强调了最初提出的建议,即通过适当的生理学监测在多种动物物种中采用组织学和功能结局来确定可重复的剂量反应和时间窗。更新后的STAIR推荐意见包括:高质量科学研究的基本原则应消除随机和评价偏倚,预先确定纳入和排除标准,计算合适的效能和样本量,并公开潜在的利益冲突。应在年轻的健康雄性动物中进行初步评价之后,在雌性、高龄动物和伴有合并症(如高血压、糖尿病和高胆固醇血症)的动物中做进一步研究。此外还要在动物实验中应用临床相关生物学标志物。尽管只有通过临床试验产生基于此的有效疗法之后才能证实该推荐意见的有效性,但遵循这些推荐有望提高成功的机会。 | Marc Fisher Giora Feuerstein David W. Howells Patricia D. Hum Thomas A. Kent Sean I. Savitz Eng H. Lo 吕志宿(译) 罗本燕(译) | 2009 | 国际脑血管病杂志2009，17，8： | 5 |
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