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| 1 | 推荐以“EBV相关肺癌”术语替代和扩展肺淋巴上皮瘤样癌的组织学谱系显示文摘肺淋巴上皮瘤样癌(LELC)是一种罕见的EBV相关性癌,其组织学特征为癌细胞呈合体细胞样生长,伴显著的淋巴细胞浸润,组织学上与未分化型鼻咽癌难以区分。研究发现LELC亦可显示非经典组织学形态且缺乏显著的淋巴细胞浸润。作者选取61例肺LELC病例进行全面临床病理分析,并使用免疫组化分析软件对浸润淋巴细胞进行自动定量分析,发现肺LELC形态学上存在连续性谱系,呈现从富于淋巴细胞浸润的经典型未分化LELC至极少淋巴细胞浸润的非经典型组织学形态。 | Yeh Y C Kao H L Lee K L | 2019 | 临床与实验病理学杂志2019，35，5： | 12 |
| 2 | Microscopic colitis:A large retrospective analysis from a health maintenance organization experience显示文摘AIM:To examine the demographic data on a large multi-ethnic population of patients with microscopic colitis (MC) in Southern California and to determine the association of MC with inflammatory bowel disease (IBD) and colorectal cancer.METHODS: All patients diagnosed with MC by colonic biopsy from 1996-2005 were identified utilizing a pathology database. All biopsies were reviewed by experienced pathologists utilizing standard histologic criteria. Patients' medical records were reviewed and data regarding patient age, co-morbidities, sex, ethnicity, and medications were analyzed. An age-and sexmatched standard control group was also generated. Chi-square test was used to evaluate the associations of co-morbidities between lymphocytic colitis (LC), collagenous colitis (CC) and the control group.RESULTS: A total of 547 cases of MC were identif ied,376 patients with LC and 171 patients with CC. The female/male ratio was 3:1 in CC and 2.7:1 in LC patients. Celiac disease (P<0.001), irritable bowel syndrome (IBS) (P<0.001), and thyroid diseases (P<0.001) were found to have a higher occurrence in MC compared to the control group. No statistical differences in the occurrence of colorectal cancer, diabetes and IBD were found between the MC group and the control group.CONCLUSION: This is the largest group of patients with MC known to the authors that has been studied to date. Conditions such as celiac disease, IBS, and thyroid diseases were found to be related to MC. Furthermore, neither an increased risk of colorectal cancer nor IBD was associated with MC in this study. | Kevin T Kao Benito A Pedraza Amy C McClune David A Rios Yi-Qiong Mao Robert H Zuch Michael H Kanter Sony Wirio Chris N Conteas | 2009 | World Journal of Gastroenterology2009，15，25： | 5 |
| 3 | 肾脏恶性孤立性纤维性肿瘤过表达BCOR:模拟肾脏透明细胞肉瘤显示文摘BCOR是诊断肾脏透明细胞肉瘤(CCSK)的一种敏感且高度特异的标志物。然而,过表达BCOR的成人肾脏肉瘤中有一部分BCOR基因遗传学改变(包括BCOR基因融合或BCOR内部串联重复)却呈阴性,因此被归为不能分类的肾脏肉瘤。作者报道了5例肾脏/肾周未分化肉瘤,鉴于其形态学特征和高表达BCOR,提示需与CCSK进行鉴别,但经过RNA测序证实为恶性孤立性纤维性肿瘤(SFTs)。发病年龄30~62岁,女性3例,男性2例。4例为原发性肾脏肿瘤,1例为肾周肿瘤。5例肿瘤均为富于细胞性、非多形性的未分化肉瘤,具有毛细血管分支,由圆形至卵圆形肿瘤细胞组成,胞质稀少,核规则,染色质均匀分布。5例中均未出现SFTs的典型特征,如浓染的梭形核、明显的胶原沉积或血管外皮瘤样结构。5例BCOR均强阳性。3例CD34阴性,2例CD34仅局灶阳性。随后免疫组化结果发现,5例STAT6均阳性。 | 魏建国(摘译) 方三高(审校) Argani P Kao Y C Zhang L | 2019 | 临床与实验病理学杂志2019，35，8： | 3 |
| 4 | MUC4阴性的硬化性上皮样纤维肉瘤亚型可检出伴高频性YAP1和KMT2A基因重排显示文摘硬化性上皮样纤维肉瘤是一种侵袭性软组织肉瘤,其组织学特征为在致密硬化的胶原间质内散在上皮样细胞,免疫组化标志物MUC4常阳性,通常存在包括EWSR1在内的基因融合。由于与低度恶性纤维黏液样肉瘤在组织形态和遗传学特征方面有一些重叠,推测两者发病机制可能存在关联。实验显示有一小部分硬化性上皮样纤维肉瘤免疫组化MUC4阴性,且缺乏典型EWSR1/FUS基因重排。作者最初发现3例为MUC4阴性及EWSR1/FUS基因重排阴性的硬化性上皮样纤维肉瘤,经靶向RNA测序检测发现存在YAP1-KMT2A融合。 | Kao Y C Lee J C Zhang L 王婷(摘译) 余英豪(审校) | 2020 | 临床与实验病理学杂志2020，36，8： | 2 |
| 5 | Endometriosis显示文摘 | Linda C Giudice Lee C Kao | 2004 | 2004 (9447)2004，，9447： | 2 |
| 6 | Perioperative glycemic control and the risk of infectious complications in a cohort of adults with diabetes显示文摘 | Peart-Vigilance C Kao WHL | 1999 | Diabetes Care1999，22，9： | 1 |
| 7 | Lax-Friedrichs sweeping scheme for static Hamihon-Jacobi equations 显示文摘 | C Y Kao S Osher J Qian | 2004 | Journal of Computational Physics2004，196，1： | 1 |
| 8 | Evaluation on the wear,tension and fatigue behavior of various PVD coated materials显示文摘 | SU Y L WU C T KAO W H | 1998 | Materials Letters1998，35，34： | 1 |
| 9 | Incidental placental choriocarcinoma in a term pregnancy:a case report显示文摘 | Chung C Kao MS Gersell D | 2008 | J Med Case Reports2008，16，2： | 1 |
| 10 | Accurate image reconstruction from few views and limited angle data in divergent beam CTc显示文摘 | Emil Y S Kao C Pan X | 2006 | Jr*urna! o/X- Ray Seiezzce and Teehnology2006，14，2： | 1 |
| 11 | Dpurious Regression and Residual - based Tests for Cointegra- tion in Panel Data 显示文摘 | Kao C | 1999 | Journal of Econometrics1999，，90： | 1 |
| 12 | Cellular eardiomyoplasty:Myocardial regeneration with satellite cell implantation显示文摘 | Chiu R C J Zibaitis A Kao R L | 1995 | Ann Thorac Surg1995，60，： | 1 |
| 13 | RNA motifs that determine specificity between a viral replicase and its promoter显示文摘 | Kim C Kao C C Tinoco I | 2000 | Nat Struct Biol2000，7，： | 1 |
| 14 | Early activation of transcription factor NF-κB during ischemia in perfused rat heart 显示文摘 | Li C Browder W Kao R | 1999 | Am J Physiol1999，276，2： | 1 |
| 15 | low-dose intraoperative mitomycin cas chemoadjuvent for pteryium surgery 显示文摘 | Cheng H C Tseng S H Kao P L | 2001 | Cornea2001，20，1： | 1 |
| 16 | BACE1 suppression by RNA interference in primary cortical meurons显示文摘 | Kao S C Krichevsky A M Kosik K S | 2004 | Biol Chem2004，279，3： | 1 |
| 17 | Influence of thermal effect on output power optimization in fiber-coupled laser- diode end-pumped lasers 显示文摘 | Chert Y F Huang T M Kao C F | 1997 | IEEE J Quantum Electron1997，3，1： | 1 |
| 18 | Retrieval of surface parameters u- sing dynamic learning neutral network 显示文摘 | Chen K S Kao W L Tzeng Y C | 1995 | International Journal of Remote Sensing1995，16，5： | 1 |
| 19 | Reimplantation of a contaminated and de'Atal- ized bone fragment after autoclaving in an open fracture显示文摘 | Kao JT Comstock C | 1995 | J Orthop Trauma1995，9，： | 1 |
| 20 | Accumulation of ammonium in rice leaves in response to excess cadmium显示文摘 | CHIEN H F KAO C H | 2000 | Plant Science2000，156，： | 1 |
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