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| 1 | 曲马多治疗糖尿病性神经疼痛的双盲随机试验显示文摘目的 :本研究旨在评价曲马多治疗糖尿病性神经痛的有效性和安全性。背景 :糖尿病性神经痛是糖尿病患者的主要症状 ,其治疗和其他的末梢神经病变一样 ,不能令人满意。曲马多是作用于中枢的镇痛剂 ,用于治疗中到重度疼痛。方法 :多中心、门诊病例、随机、双盲、安慰剂做对照、设置平行组的研究 ,包括清洗期 (在此期间停用所有镇痛剂 )和一个为期 42天的双盲治疗期。总共有 1 31名患糖尿病性神经痛的患者按每日 4次接受了曲马多 (n =65)或看上去与曲马多相同的安慰剂胶囊治疗 (n =66)。 42天的治疗结束后或治疗中断后比较曲马多组和安慰剂组平均疼痛强度评分作出主要有效性分析 ;次要有效性分析为疼痛缓解率评分和根据日常活动和睡眠状况作出的对生活质量的评估。结果 :曲马多平均剂量为 2 1 0mg/天 ,治疗糖尿病性神经痛较安慰剂有显著疗效 (P≤ 0 .0 0 1 )。曲马多组患者生理(P =0 .0 2 )和社会功能 (P =0 .0 4 )的评分显著优于安慰剂组。未发现对睡眠有显著治疗作用。曲马多最常见的不良反应是恶心 ,便秘 ,头疼和嗜睡。结论 | Harati Y Gooch C Swenson M Green D Raskin P Donofrio P Cornblath D Sachdeo R Siu CO Kamin M | 2001 | 中国疼痛医学杂志2001，7，1： | 2 |
| 2 | Tramadol allows reduction of noproxen dose among patients with naproxerr responsive osteoarthritis pain:a randomized,double- blind,placebo, controlled study显示文摘 | Schnitzer TJ Kamin M Olson WH | 1999 | Arthritis Rheum1999，42，7： | 1 |
| 3 | Research joint ventures and R&D cartels显示文摘 | Kamin M I Muller E Zang 1 | 1992 | American Economic Review1992，，82： | 1 |
| 4 | A model for conduction in polycrystalline silicon-part Ⅰ: Theory 显示文摘 | Mandurah M M Saraswat K C Kamins T I | 1981 | IEEE Trans Electron Devices1981，，28： | 1 |
| 5 | The use of nonablative radiofrequency technology to tighten the lower face and neck显示文摘 | HSU T S KAMINER M S | 2003 | Semin Cutan Med Surg2003，22，2： | 1 |
| 6 | Research Joint Venture and R&D Cartds显示文摘 | KAMIN M I MULLER E ZHANG I | 1992 | American Economic Review1992，82，： | 1 |
| 7 | Suitable blending method of lipiodol-cisplatin in transcatheter arterial embolization for hepatocellular carcinoma:evaluation of sustained release and accumulation nature显示文摘 | Takaki Y Kaminou T Shabana M | 2008 | Hepatogastroenterology2008，55，81： | 1 |
| 8 | 查看详情显示文摘 | Kaminer I Segev M Christodoulides D N | | 0，，： | 1 |
| 9 | Rumor has it:The moderating effect of identification on rumor impact and the effectiveness of rumor refutation显示文摘 | E1NWILLER S A KAMINS M A | 2008 | Journal of Applied Social Psychology2008，38，9： | 1 |
| 10 | Influence of ethanol- induced pulmonary embolism on hemodynamics in pigs 显示文摘 | Yata S Hashimoto M Kaminou T | 2013 | Ann Card Anaesth2013，16，4： | 1 |
| 11 | Rumor has it: The moderating effect of identification on rumor impact and the effectiveness of rumor refutation 显示文摘 | EINWILLER S A KAMINS M A | 2008 | Journal of Applied Social Psychology2008，38，9： | 1 |
| 12 | Causality effects on accelerating light pulses显示文摘 | Kaminer I Lumer Y Segev M | 2011 | Optics Express2011，19，23： | 1 |
| 13 | Research Joint Venture and R&D Cartels显示文摘 | Kamin M L Muller E Zhang I | 1992 | American Economic Review1992，82，6： | 1 |
| 14 | On secret sharing systems 显示文摘 | Kamin E D Greene J W Hellman M E | 1983 | IEEE Transations on Information Theory1983，29，： | 1 |
| 15 | An investigation into the match-up-hypothesis in celebrity advertising: When beauty be only skin deep显示文摘 | Kamins M A | 1990 | Journal of Advertising1990，19，1： | 1 |
| 16 | Congruence between spokesperson and product type: A matchup hypothesis perspective显示文摘 | Kamins M A Gupta K | 1994 | Psychology and Marketing1994，11，6： | 1 |
| 17 | Examining the Roles of Job Involvement and Work Centrality in Predicting Organizational Citizenship Behaviors and Job Performance显示文摘 | Diefendorff M Brown DJ Kamin AM | 2002 | Journal of Organizational Behavior2002，23，1： | 1 |
| 18 | Effects of informationabout firms,ethical and unethical on consumers,attitudes 显示文摘 | Folkers V S- Kamins M A | 1999 | Joural of Consumer Psychology1999，12，8： | 1 |
| 19 | Person versus process praise and criticism: Implications for contingent self-worth and coping 显示文摘 | KAMINS M L DWECK C S | 1999 | Developmental Psychology1999，，35： | 1 |
| 20 | Topiramate titration to response: analysis of individualized therapy study (TRAITS)显示文摘 | Dodson WE Kamin M Kraut L | 2003 | Ann Pharmacother2003，37，5： | 1 |
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