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1Meta-analyses on prevalence of selected Parkinson’s nonmotor symptoms before and after diagnosis显示文摘Background:Nonmotor symptoms are common among patients with Parkinson’s disease(PD)and some may precede disease diagnosis.Methods:We conducted a meta-analysis on the prevalence of selected nonmotor symptoms before and after PD diagnosis,using random-effect models.We searched PubMed(1965 through October/November 2012)for the following symptoms:hyposmia,constipation,rapid eye movement sleep behavior disorder,excessive daytime sleepiness,depression,and anxiety.Eligible studies were publications in English with original data on one or more of these symptoms.Results:The search generated 2,373 non-duplicated publications and 332 met the inclusion criteria,mostly(n=320)on symptoms after PD diagnosis.For all symptoms,the prevalence was substantially higher in PD cases than in controls,each affecting over a third of the patients.Hyposmia was the most prevalent(75.5%in cases vs.19.1%in controls),followed by constipation(50%vs.17.7%),anxiety(39.9%vs.19.1%),rapid eye movement sleep behavior disorder(37.0%vs.7.0%),depression(36.6%vs.14.9%),and excessive daytime sleepiness(33.9%vs.10.5%).We observed substantial heterogeneities across studies and meta-regression analyses suggested that several factors might have contributed to this.However,the prevalence estimates were fairly robust in several sensitivity analyses.Only 20 studies had data on any symptoms prior to PD diagnosis,but still the analyses revealed higher prevalence in future PD cases than in controls.Conclusion:These symptoms are common among PD patients both before and after diagnosis.Further studies are needed to understand the natural history of nonmotor symptoms in PD and their etiological and clinical implications.Honglei Chen Edward J Zhao Wen Zhang Yi Lu Rui Liu Xuemei Huang Anna J Ciesielski-Jones Michele A Justice Deborah S Cousins Shyamal Peddada 2015Translational Neurodegeneration2015,4,1:18
2Sympathetic skin response:a new test to diagnose erectile dysfunction显示文摘Electrophysiological monitoring of the activity of the penile sympathetic skin responses (PSSR) in healthy men and patients with erectile dysfunction (ED). Methods: PSSR were recorded from the skin of penis with disk electrodes at the time of electric stimulation of left median nerves. Results: PSSR were recorded from all the healthy men and almost all the patients. In healthy men the latency of P0, the latency of N1, the duration of N1 and the amplitude of N1 were 1249 ± 111 ms, 2239 ± 286 ms, 1832 ± 505 ms and 470 μV (median), respectively. In ED patients the latency of P0, the latency of N1, the duration of N1 and the amplitude of N1 were 1467 ± 183 ms ( P < 0.01), 2561±453 ms (P <0.05), 2560±861 ms (P <0.01) and 91 μV (P <0.01), respectively. The normal latency of P0 was less than 1471 ms. The normal amplitude of N1 was more than 235 μV. According to this normal value, of 20 patients 11 showed longer latency of P0, and 14 showed lower amplitude of N1 as compared with those of normal subjects.Conclusion: PSSR can be used as an electrophysiological method in assisting the diagnosis of ED.Guang-You ZHU Yan SHEN Institute of Forensic Sciences, Ministry of Justice, China, Shanghai 200 063,China. 2001Asian Journal of Andrology2001,3,1:10
3基于高通量测序技术分析2种菌草根际土壤真菌群落多样性显示文摘为了解福州菌草基地巨菌草和绿洲一号2种菌草的根际土壤真菌群落多样性,采用Illumina Miseq高通量测序技术和生物信息学方法,对菌草根际土真菌的多样性及群落结构进行分析。结果表明:从3份土壤样本中获得525 292条ITS序列,在97%序列相似性基础上可划分为7267个可操作分类单元(OTU)。真菌群落的丰富度指数(ACE)以菌草非根际土最低,绿洲一号根际土略高于巨菌草根际土;而多样性指数(Shannon-Wiener和Simpson)菌草根际土高于非根际土,绿洲一号根际土略高于巨菌草根际土。3份样品的优势菌门为子囊菌门(Ascomycota)、担子菌门(Basidiomycota)、接合菌门(Zygomycota)、壶菌门(Chytridiomycota)、球囊菌门(Glomeromycota);优势菌纲为散囊菌纲(Eurotiomycetes)、粪壳菌纲(Sordariomycetes)、座囊菌纲(Dothideomycetes)、伞菌纲(Agaricomycetes)、锤舌菌纲(Leotiomycetes)、圆盘菌纲(Orbiliomycetes)、银耳纲(Tremellomycetes)、粘膜菌纲(Wallemiomycetes);优势菌属为篮状菌属(Talaromyces)、深黄伞形霉属(Umbelopsis)、枝孢菌属(Cladosporium)、暗双孢菌属(Cordana)、镰刀菌属(Fusarium)、隐球菌属(Cryptococcus)、淡紫紫霉属(Purpureocillium)、赤霉菌属(Gibberella)、灵芝属(Ganoderma)。研究结果表明,菌草根际土真菌群落多样性高于非根际土,为进一步更好地利用菌草提供理论参考依据。叶文雨 谢序泽 许钰滢 倪明月 胡红莉 余文英 Norvienyeku Justice 鲁国东 2020热带作物学报2020,41,3:9
4Application of pudendal evoked potentials in diagnosis of erectile dysfunction显示文摘Aim: Extensive neurophysiological investigations were carried out in I00 healthy subjects and 84, patients with penile erectile dysfunction.Guang-You ZHU Yan SHEN Institute of Forensic Sciences, Ministry of Justice, Shanghai 200063, China 1999Asian Journal of Andrology1999,1,3:6
5农村法律援助工作调研报告显示文摘Legal Aid Center of the Ministry of Justice 2007中国司法2007,,12:5
6PacBio Sequencing Reveals Transposable Elements as a Key Contributor to Genomic Plasticity and Virulence Variation in Magnaporthe oryzae显示文摘Jiandong Bao Meilian Chen Zhenhui Zhong Wei Tang Lianyu Lin Xingtan Zhang Haolang Jiang Deyu Zhang Chenyong Miao Haibao Tang Jisen Zhang Guodong Lu Ray Ming Justice Norvienyeku Baohua Wang Zonghua Wang 2017Molecular Plant2017,10,11:5
7Regional fire monitoring and NASA MODIS fire products characterization using global in dry lands of Central Asia显示文摘Tatiana V. LOBODA Louis GIGLIO Luigi BOSCHETTI Christopher O. JUSTICE 2012Frontiers of Earth Science2012,6,2:5
8关于进一步做好戒毒康复工作的调研报告显示文摘Bureau of Reform-through-labour, Ministry of Justice 2009中国司法2009,,1:4
9全国法律援助“规范与质量”情况调研报告显示文摘The Legal Aid Centre of the Ministry of Justice 2007中国司法2007,,4:2
10Gq signaling is required for allergen-induced pulmonary eosinophilia显示文摘Borchers M T Justice P J Ansay T 2002J Immunol2002,168,7:2
11Bwta2 - microglobulin clearance in neonates: Index of tubular maturation显示文摘Assadi FK John EG Justice JP 1985Kidney Int1985,28,4:2
12微胶囊饲料一些理化指标的测定与评价显示文摘[目的]研究微胶囊饲料的理化性质。[方法]以大黄鱼仔稚鱼微胶囊饲料为研究对象,测定了微胶囊饲料的一些理化指标。[结果]1号饲料的平均粒径为(27.77±1.18)μm,颗粒呈圆形或椭圆形,分布均匀;2号饲料的平均粒径为(34.73±1.76)μm,颗粒呈不规则形,大小分布不均匀。微胶囊饲料粒径在20~40μm;微胶囊饲料的悬浮率和溶解率均偏低。在海水中浸泡2 h后,微胶囊饲料1号浸泡液的pH为(6.800±0.056),氨氮浓度为(0.052±0.003)mg/L,亚硝酸盐浓度为(0.412±0.006)mg/L;微胶囊饲料2号浸泡液的pH为(6.683±0.031),氨氮浓度为(0.047±0.005)mg/L,亚硝酸盐浓度为(0.493±0.026)mg/L。微胶囊饲料对水体有一定的影响,浸泡液偏酸性,但对水体中氨氮和亚硝酸盐浓度的影响不大。[结论]试验所用微胶囊饲料基本满足大黄鱼苗开口时期的摄食要求,但其加工工艺有待进一步完善。梁萍 严美姣 林建斌 朱庆国 邱曼丽 IJEOMA CHRIS JUSTICE 2018安徽农业科学2018,46,9:2
13Metamaterial Electromagnetic Cloak at Microwave Frequencies 显示文摘Schurig D Mock J J Justice B J 2006Science2006,314,5801:1
14Nutrient changes in the Mississippi River and system responses on the adjacent continental shelf显示文摘RABALAIS N N WISEMAN W J Jr JUSTIC D 1996Estuaries1996,19,:1
15Metameterial elec- tromagnetic cloak at microwave frequencies 显示文摘Schurig D Mock J J Justice B J 2006Science2006,314,:1
16Variations on the Notch pathway in neu- ral development显示文摘Justice N J Jan YN 2002Curr Opin Neurobiol2002,12,:1
17Accuracy of ultrasonography for the diagnosis of intussusception in infants in Vietnam显示文摘Justice FA De Campo M Liem NT 2007Pediatr Radiol2007,37,2:1
18Management of incidental pituitary microadenomas: a cost-effectiveness analysis显示文摘King JT Jr Justice AC Aron DC 1997J Clin Endocrinol Metabol1997,82,11:1
19The ica operon and biofilm prodution in coagulase negative staphylococci associated with carriage and disease in a neonatal intensive care unit显示文摘de SILVA G D KANTZANOU M JUSTICE A 2002J Clin Microbiol2002,40,:1
20Does ' ICU psychosis' really exist? 显示文摘Justic M 2000Crit Care Nurse2000,20,3:1
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