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| 1 | Fecal microbes, short chain fatty acids, and colorectal cancer across racial/ethnic groups显示文摘AIM:To investigate differences in microbes and short chain fatty acid(SCFA) levels in stool samples from Hispanic and non-Hispanic African American,American Indian,and White participants.METHODS:Stool samples from twenty participants were subjected to analysis for relative levels of viable bacteria and for SCFA levels.Additionally,the samples were subjected to 16 S r RNA gene pyrosequencing for identification of bacteria present in the stool.We used a metagenome functional prediction technique to analyze genome copy numbers and estimate the abundance of butyrate kinase in all samples.RESULTS:We found that African Americans had significantly lower levels of acetate,butyrate,and total SCFAs than all other racial/ethnic groups.We also found that participant microbial profiles differed by racial/ethnic group.African Americans had significantly more Firmicutes than Whites,with enriched Ruminococcaceae.The Firmicutes /Bacteroidetes ratio was also significantly higher for African Americans than for Whites(P =0.049).We found Clostridium levels to be significantly and inversely related to total SCFA levels(P =0.019) and we found Bacteroides to be positively associated(P =0.027) and Clostridium to be negatively associated(P =0.012) with levels of butyrate.We also identified a correlation between copy number for a butyrate kinase predicted from 16 S r RNA gene abundance and levels of butyrate in stool.CONCLUSION:The identified differences in gut flora and SCFA levels may relate to colorectal cancer mortality differentials and may be useful as targets for future clinical and behavioral interventions. | Christina M Hester Venkatakrishna R Jala Morgan GI Langille Shahid Umar K Allen Greiner Bodduluri Haribabu | 2015 | World Journal of Gastroenterology2015，21，9： | 2 |
| 2 | Bone marrow as a home of heterogenous populations of nonhematopoietic stem cell显示文摘 | Kucia M RecaR Jala VR | 2005 | Leukmia2005，19，7： | 1 |
| 3 | Fly ash as a soil ameliorant for improving crop production-a review显示文摘 | Jala S Goyal D | 2006 | Bioresource Technology2006，97，9： | 1 |
| 4 | Mutations in COQ4,an essential component of coenzyme Q biosynthesis,cause lethal neonatal mitochondrial encephalomyopathy显示文摘 | Chung WK Martin K Jalas C Braddock SR Juusola J Monaghan KG | 2015 | J Med Genet2015，52，： | 1 |
| 5 | Energy intensive lifestyles:Time use,the activity patterns of consumers,and related energy demands in Finland显示文摘 | Jalas M Juntunen J K | 2015 | Ecological Economics2015，113，： | 1 |
| 6 | 显示文摘 | Jala S Goyal D | 2006 | Bioresource Technol2006，97，9： | 1 |
| 7 | Serum transferring receptor and its ratio to serum ferritin in the diagnosis of iron deficiency 显示文摘 | Punnonen K Ir jala K Ra jamaki A | 1997 | Blood1997，89，3： | 1 |
| 8 | Bone marrow as a home of heterogenous populations of nonhematopoietic stem cells 显示文摘 | Kucia M Reca R Jala VR | 2005 | Leukemia2005，19，7： | 1 |
| 9 | Fly ash as a soil ameliorant for impro- ving crop production 显示文摘 | Sudha Jala Dinesh Goyal | 2006 | Industrial Crops and Products2006，，3： | 1 |
| 10 | Fly ash as a soil ameliorant for improving crop production-a review显示文摘 | JALA S GOYAL D | 2006 | Bioresource Technology2006，97，9： | 1 |
| 11 | Pseudomarginati in the Himalayas and adjoining western mountain ranges, and in Caucasia显示文摘 | Jalas J Thymus subsect | 1973 | Annales Botanici Fenniei1973，10，： | 1 |
| 12 | Genetic loss of SH2B3 in acute lymphoblastic leukemia显示文摘 | Arianne Perez-Garcia Alberto Ambesi-Impiombato Michael Hadler Isaura Rigo Charles A. LeDuc Kara Kelly Chaim Jalas Elisabeth Paietta Janis Racevskis Jacob M. Rowe Martin S. Tallman Maddalena Paganin Giuseppe Basso Wei Tong Wendy K. Chung Adolfo A. Ferrando | 2013 | Blood2013，，14： | 1 |
| 13 | Role of leukotriene B4 receptors in the development of atherosclerosis:potential mechanisms显示文摘 | Subbarao K Jala VR Mathis Suttles J Zacharias W Ahamed J | 2004 | Arterioscler Thromb Vasc Biol2004，24，2： | 1 |
| 14 | Evaluation of economic value of Pilikula lake u sing travel cost and contingent valuation methods显示文摘 | JALA N L | 2015 | Aquatic Procedia2015，4，： | 1 |
| 15 | Enhanced expression of G-protein coupled estrogen receptor(GPER/GPR30)in lung cancer显示文摘 | Jala VR Radde BN Haribabu B | 2012 | BMC Cancer2012，12，： | 1 |
| 16 | Bone marrow as a home of heterogenous populations of nonhematopoietic stem cells 显示文摘 | Kucia M Reca R Jala VR | 2005 | Leukemia2005，19，7： | 1 |
| 17 | Multidrug resistance problems targeting piglets and environmental health by Escherichia coli in intensive swine farms显示文摘Multidrug resistance(MDR)problems become critical concerns in animal production through food chains and the environment.Thus,the cross-sectional study of E.coli in swine feces,drinking water,and wastewater collected on four medium and four large swine farms in Thailand was studied.The orders of antibiotics used were AMX-COL-GM-TIL and AMX-COL-GM-CER on medium-sized and large swine farms,respectively.Hemolytic E.coli(HEC)was more frequently isolated from all samples than Non-hemolytic E.coli(NHEC).The medium-sized farms were resistant to AMP,AMX,TE,and C,while large farms were resistant to AMP,AMX,TE,and PIP.Only two sensitive antibiotics,namely AK and TE,were available on both farms,whereas,banned NT was still detected in the sludge.The MDR of E.coli isolates was 95.7%and 87.7%on medium-sized and large swine farms,while the highest resistance found was 15 drugs used for NHEC on medium-sized swine farms.The PFGE molecular typing revealed the largest cluster containing five isolations,correlated with drinking water,sow,and fattening isolates;however,the phenotypic and genotypic were not in a similar pattern.The most seriously MDR related to HEC was found in the piglets,effluent,and sludge.Thus,the AMR and MDR of E.coli existence in medium-sized and large swine farms in this study.MDR of E.coli was substantially found in the environmental,including effluent and sludge.Therefore,it inevitably operates the long-term monitoring of AMR,especially targeted piglets and its environment as the main focus of critical antibiotics use in swine farms. | Atchara Dawangpa Preeda Lertwatcharasarakul Alongkot Boonsoongnern Nattavut Ratanavanichrojn Arsooth Sanguankiat Nayika Pinniam Siriluk Jala Sudtisa Laopiem Phitsanu Tulayakul | 2022 | Emerging Contaminants2022，8，1： | 1 |
| 18 | Leukotrienes and atherosclerosis:new roles for old mediators显示文摘 | Jala V R Haribabu B | 2004 | Trends in Immunology2004，25，6： | 1 |
| 19 | Heat shock protein 27 regulars neutrophil ehemotaxis and exoeytosis through two independent mechanisms显示文摘 | Jog NR Jala VR Ward RA | 2007 | J Immunol2007，178，4： | 1 |
| 20 | Hemerokorit ja hemerobit显示文摘 | | 1953 | Luonnon Tutkija1953，57，： | 1 |
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