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| 1 | Increased incidence of chemoport-related thrombosis in patients with colorectal cancer receiving bevacizumab: A single-institutional experience显示文摘Objective: Chemoport-related thrombosis(CRT) is a serious complication that causes morbidities and interrupts administration of intravenous cancer therapy. We investigated the incidence and risk of CRT in colorectal cancer(CRC) patients treated with bevacizumab(BEV).Methods: We retrospectively reviewed 1,534 CRC patients who received chemotherapy with or without BEV using a chemoport between 2014 and 2016.Results: The participants had a median age of 58(18-85) years, and 60.3% were male. All participants were stratified into three groups: adjuvant chemotherapy(AC)(n=670), palliative chemotherapy(PC) without BEV(n=356), and PC with BEV(n=508). The median follow-up was 20.19(interquartile range, 14.07-27.19) months.CRT occurred in 3.8% of all patients; incidence of symptomatic and asymptomatic CRT was 2.9% and 0.9%,respectively. CRT occurred more in patients with BEV(5.7%) than in patients without BEV(2.9%, P=0.008). The cumulative incidence of CRT in patients administered PC with BEV was significantly higher than that in those administered AC(P=0.011) and there was a trend toward increased CRT in patients administered PC with BEV compared with those administered PC without BEV(P=0.044). Multivariate analysis found that BEV treatment was the only variable that was significantly associated with CRT(hazard ratio, 2.06; 95% confidence interval, 1.24-3.43;P=0.006).Conclusions: BEV treatment was significantly associated with increased incidence of CRT in CRC patients. | Jwa Hoon Kim Jeong Eun Kim Yong Sang Hong Sun Young Kim Kyu-pyo Kim Ki Eun Choi Ji Hoon Shin Tae Won Kim | 2018 | Chinese Journal of Cancer Research2018，30，4： | 2 |
| 2 | Effects of Methylpredniaolone Pulse Therapy on Refractory Myeoplasma pneumoniae Pneumonia in Children显示文摘 | You SY Jwa H J Yang EA | 2014 | Allergy Asthma Immunol Res2014，6，1： | 1 |
| 3 | Enterovirus sequences resembling coxsackievirus A2 detected in stool and spleen from a girl with fatal myocarditis显示文摘 | Bendig JWA O'Brien PS Muir P | 2001 | J Med Virol2001，64，4： | 1 |
| 4 | Diagnosis and treatment of portal vein thrombosis following splenectomy 显示文摘 | Riet MV Burger JWA Muiswinkel JMV | 2000 | Br J Surg2000，87，： | 1 |
| 5 | Myocardial steatosis is an independent predictor of diastolic dysfunction in type 2 diabetes mellitus 显示文摘 | Rijzewijk LJ van der Meer RW Smit JWA | 2008 | J Am Coil Cardiol2008，52，22： | 1 |
| 6 | Quantitative study of cell death in the substantia nigra following a mechanical lesion of the medical forebrain bundle 显示文摘 | Brecknell JE Dunnett SB Fawcett JWA | 1995 | Neuroscience1995，64，： | 1 |
| 7 | The role of hipp-ocampal sclerosis in topiramate-related depression and cognitive deficits in people with epilepsy显示文摘 | Mula M Trimble MR Sander JWAS | 2003 | Epilepsia2003，44，2： | 1 |
| 8 | Diagnosis and treatment of portal vein thrombosis following splenectomy显示文摘 | Van't Riet M Burger JWA Van Muiswinkel JM | 2000 | Br J Surg2000，87，： | 1 |
| 9 | Molecular cloning and mRNA expression analysis of the first rice jasmonate biosynthetic pathway gene allene oxide synthase显示文摘 | Agrawal G K Rawal R Jwa N S | 2002 | Plant Physiology and Biochemistry2002，40，： | 1 |
| 10 | Bioanalytical method validation-a revisit with a decade of progress显示文摘 | Shah VP Midha KK Findlay JWA | 2000 | Pharma Res2000，17，12： | 1 |
| 11 | Stress signaling molecules involved in defense and protein phosphatase 2A inhibitors modulate OsCATC expression in rice(Oryza sativa) seedlings显示文摘 | Agrawal G K Rakwal R Jwa N S | 2011 | J Plant Physiol2011，58，： | 1 |
| 12 | Natural history and prognosis of cervical spondylosis显示文摘 | Lees F Turner JWA | 1963 | Br Med J1963，2，： | 1 |
| 13 | Effects of Methylprednisolone Pulse Therapy on Refractory Mycoplasma pneumoniae Pneumonia in Children显示文摘 | You SY Jwa HJ Yang EA | 2014 | Allergy Asthma Immunol Res2014，6，1： | 1 |
| 14 | Bioanalytical method validation- arevisit with a decade of progress 显示文摘 | Shah VP Midha KK Findlay JWA | 2000 | Pharm Res2000，17，12： | 1 |
| 15 | Diagnostic value of serum thyroglobulin measurements in the follow-up of differentiated thyroid carcinoma,a structured meta-analysis显示文摘 | Eustatia-Rutten CFA Smit JWA Romijn JA | 2004 | Clin Endocrinol2004，61，1： | 1 |
| 16 | Four DAZ genes in two clusters found in the AZFc region of the human Y chromosome 显示文摘 | Saxena R de Vries JWA Repping S | 2000 | Genomics2000，67，3： | 1 |
| 17 | Oryza sativa proteinase inhibitor gene,OsPIN,whose mRNA specifically accumulates in a compatible host-blast pathogen interaction显示文摘 | Agrawal G K Rakwal R Jwa N S | 2002 | Plant Physiology and Biochemistry2002，40，： | 1 |
| 18 | Importance of acer- bate peroxides OsAPX1 and OsAPX2 in the rice pathogen re- sponse pathways and growth and reproduction revealed by their transcriptional profiling显示文摘 | Agrawal G K Jwa N S Iwahashi H etal | 2003 | Gene2003，322，： | 1 |
| 19 | Changes in enzymeactivities and microbial biomass of tall grass prairie soilas related to burning and nitrogen fertilization显示文摘 | A jwa H A Dell C J Rice C W | 1999 | SoilBiology B - iochemistry1999，31，5： | 1 |
| 20 | Effects of Methylprednisolone Pulse Therapy on Refractory Mycoplasma pneumoniae Pneumonia in Children显示文摘 | You SY Jwa HJ Yang EA | 2014 | Allergy Asthma Immunol Res2014，6，1： | 1 |
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