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| 1 | Endothelial cell-derived GABA signaling modulates neuronal migration and postnatal behavior显示文摘服的外皮为集成是必要的并且为大多数行为被要求的信息处理。当神经原从室的地区连续地移居联合进特定的外皮的层时,服的外皮的精致地精确的 laminar 组织在胚胎的开发期间产生。当时指南为设计神经原移植责骂的光线的神经胶质行为, pre-formed 脉管的网络为 GABAergic interneuron 移植提供支持和指导暗示。这研究提供新奇概念、机械学的卓见进 vascular-neuronal 相互作用的这个范例,揭示伽马氨基丁酸并且它经由胚胎的前脑 endothelial 房间的调停受体的发信号的新机制。与二个新 endothelial 房间的使用,特定的有条件的老鼠 GABA 小径当模特儿(Gabrb3 Tie2-Cre 和 Vgat 我们显示出的 Tie2-Cre ), 从 endothelial 房间的伽马氨基丁酸版本的那部分或完全的损失在 embryogenesis 期间导致脉管的缺点并且损害长途的移植并且外皮的 interneurons 放。使不安的 endothelial 的下游的效果导出房间的伽马氨基丁酸发信号是批评的,导致上次修改到外皮的电路和坚持的行为的赤字。而且,我们说明在支持他们血大脑障碍性质的迁居, angiogenesis 和获得的前脑 endothelial 房间发信号的伽马氨基丁酸的激活的新机制。我们的调查结果揭开并且阐明在从表明小径的古典 neuronal 伽马氨基丁酸是不同的并且在 neuropsychiatric 疾病的病原学和 pathophysiology 上打开新灯的 CNS 表明小径的新奇 endothelial 伽马氨基丁酸例如孤独性光谱混乱,癫痫,焦虑,消沉和精神分裂症。 | Suyan Li Peeyush Kumar Sampada Joshee Timo Kirschstein Sivan Subburaju Jahan S Khalili Jonas Kloepper Chuang Du Abdallah Elkhal Gabor Szabo Rakesh K Jain Rudiger Kohling Anju Vasudevan | 2018 | Cell Research2018，28，2： | 3 |
| 2 | Plasma vascular endothellal but fibroblast growth factor levels correlate with colorectal liver metastasls vascularlty and volume显示文摘 | Davles M M Jonas S K Kaur S | 2000 | Br J Canoer2000，82，5： | 1 |
| 3 | Twinning and texture development in two Mg alloys subjected to loading along three dif- ferent strain paths显示文摘 | JIANG L JONAS J J MISHRA R K | 2007 | Acta Materialia2007，55，11： | 1 |
| 4 | Diet preference of lambs offered a choice of concentrate di- ets containing different proportions of wheat dried dis- tiller' s grain with solubles 显示文摘 | CHARLES E K R JONAS E CHAVES A V | 2012 | Small Ruminant Re- search2012，108，123： | 1 |
| 5 | Monitoring glaucoma progression with visual evoked potentials of the blue-sensitive pathway显示文摘 | HORN F K JONAS J B BUDDE W M | 2002 | Invest Ophthalmol Vis Sci2002，43，6： | 1 |
| 6 | Cold rolling and annealing textures in low carbon and extra low carbon steels显示文摘 | Jonas J J Hook R K | 1994 | International Materials Reviews1994，39，4： | 1 |
| 7 | Unusual Malignant Coronary Artery Anomaly: Results of Coronary Angiography, MR Imaging, and Multislice CT显示文摘 | Jonas Apitzsch Harald P. Kühl Georg Mühlenbruch Andreas H. Mahnken | 2010 | CardioVascular and Interventional Radiology2010，，： | 1 |
| 8 | Influence of (10-12) extension twinning on the flow behavior of AZ31 Mg alloy 显示文摘 | JIANG L JONAS J J LUO A A SACHDEV A K GODET S | 2007 | Materials Science and Engineering A2007，，： | 1 |
| 9 | Relationship between tumor vascularity and circulating cancer cells in patients with colorectal carcinoma显示文摘 | Mathur P Wharton R Q Jonas S K | 2001 | Eur J Surg Oncol2001，27，35： | 1 |
| 10 | Cold rolling and annealing textures in low carbon and extra low carbon steels显示文摘 | RAY R K JONAS J J HOOK R E | 1994 | International Materials Reviews1994，39，： | 1 |
| 11 | Complex regulatory network encompassing the Csr, c-di-GMP and motility systems of Salmonella Typhimurium显示文摘 | Jonas K Edwards AN Ahmad I | 2010 | Environ Microbiol2010，12，2： | 1 |
| 12 | Effect of manganese on recrystallisation kinetics of niobium microalloyed steel显示文摘 | Cho S H Kang K B Jonas J J | 2002 | Mater Sci Technol2002，18，3： | 1 |
| 13 | Do depression symptoms predict early hypertension incidence in young adults in the CARDIA study显示文摘 | Davidson K Jonas BS Dixon KE | 2000 | Arch Intern Med2000，160，10： | 1 |
| 14 | Pschologic factors as precursors to hypetension显示文摘 | Jonas BS Davidson K | 2001 | Curr Hypertens Rep2001，3，1： | 1 |
| 15 | Trans- formation textures in steels 显示文摘 | RAY R K JONAS J J BUTRON M P | 1994 | ISIJ International1994，34，12： | 1 |
| 16 | Cold roiling and annealing textures in low carbon and extra low carbon steels 显示文摘 | Ray R K Jonas J J Hook R E | 1994 | International Materials Review1994，39，4： | 1 |
| 17 | Transformation Textures in Steels 显示文摘 | Ray R K Jonas J J | 1990 | International Materials Reviews1990，35，1： | 1 |
| 18 | Twinning-induced softening in polycrystalline AM30 Mg alloy at moderate temperatures 显示文摘 | JIANG L JONAS J J LUO A A SACHDEV A K GODET S | 2006 | Scripta Materialia2006，54，： | 1 |
| 19 | Msthematical modeling of the recrystallization kinetics of Nb microaUoyed steels 显示文摘 | Cho S H Kang K B Jonas J J | 2001 | ISIJ International2001，41，7： | 1 |
| 20 | Cold Rolling and Annealing Textures in Low Carbon and Extra Low Carbon Steels显示文摘 | Ray K Jonas J J Hook R E | 1994 | Inter Mater Rev1994，39，4： | 1 |
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