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    题名 作者 年代 出处 被引量
1Semiconductor metal oxide compounds based gas sensors: A literature review显示文摘Sunil Jagannath PATIL Arun Vithal PATIL Chandrakant Govindrao DIGHAVKAR Kashinath Shravan THAKARE Ratan Yadav BORASE Sachin Jayaram NANDRE Nishad Gopal DESHPANDE Rajendra Ramdas AHIRE 2015Frontiers of Materials Science2015,9,1:5
2Expression of human FUS/TLS in yeast leads to protein aggregation and cytotoxicity,recapitulating key features of FUS proteinopathy显示文摘Mutations in the fused in sarcoma/translocated in liposarcoma(FUS/TLS)gene have been associated with amyotrophic lateral sclerosis(ALS).FUS-positive neuropathology is reported in a range of neurodegenerative diseases,including ALS and fronto-temporal lobar degeneration with ubiquitin-positive pathology(FTLDU).To examine protein aggregation and cytotoxicity,we expressed human FUS protein in yeast.Expression of either wild type or ALS-associated R524S or P525L mutant FUS in yeast cells led to formation of aggregates and cytotoxicity,with the two ALS mutants showing increased cytotoxicity.Therefore,yeast cells expressing human FUS protein recapitulate key features of FUSpositive neurodegenerative diseases.Interestingly,a significant fraction of FUS expressing yeast cells stained by propidium iodide were without detectable protein aggregates,suggesting that membrane impairment and cellular damage caused by FUS expression may occur before protein aggregates become microscopically detectable and that aggregate formation might protect cells from FUS-mediated cytotoxicity.The N-terminus of FUS,containing the QGSY and G rich regions,is sufficient for the formation of aggregates but not cytotoxicity.The C-terminal domain,which contains a cluster of mutations,did not show aggregation or cytotoxicity.Similar to TDP-43 when expressed in yeast,FUS protein has the intrinsic property of forming aggregates in the absence of other human proteins.On the other hand,the aggregates formed by FUS are thioflavin T-positive and resistant to 0.5%sarkosyl,unlike TDP-43 when expressed in yeast cells.Furthermore,TDP-43 and FUS display distinct domain requirements in aggregate formation and cytotoxicity.Kazuo Fushimi Charles Long Neha Jayaram Xiaoping Chen Liming Li Jane Y.Wu 2011Protein & Cell2011,2,2:4
3Supply chain integration with third-party logistics providers显示文摘Jayanth Jayaram Keah-Choon Tan 2010International Journal of Production Economics2010,,2:2
4Taxonomic status of the Chinese catfish famiiiy Cranoglanididae Myers 显示文摘Jayaram K C 1955Proc Nat Inst Sei India1955,1,6:1
5Steroid nave eosinophilie asthma: anti - inflammatory effects of fluticamne and montelukast 显示文摘JAYARAM L PIZZICHINI E LEMIIERE C 2005Thorax2005,60,2:1
6Virtual assembly using virtual reality techniques 显示文摘Jayaram S Connacher H I Lyons K W 1997Computer-Aided Design1997,29,8:1
7Virtual Assembly Using Virtual Reality Techniques显示文摘Jayaram S Connacher H Lyons K 1997Computer-Aided Design1997,29,8:1
8The effects of internal ver- sus external integration practices on time-based perfor- mance and overall firm performance 显示文摘Droge C Jayaram J Vickery S K 2004Journal of Opera- tions Management2004,22,6:1
9Fabrication and mechanisms of densification of ZrB2-based ultra high tempera- ture ceramics by reactive hot pressing显示文摘RANGARAJ L DIVAKAR C JAYARAM V 2010Journal of the Europe- an Ceramic Society2010,30,:1
10Pregnancy complicated by aortic dissection: caesarean delivery during extradural anaesthesia显示文摘Jayaram A Carp HM Davis L 1995Br J Anaesth1995,75,3:1
11Internal and external integration for product development: The contingency effects of uncertainty, equivocality, and platform strategy显示文摘Koufteros X Vonderembse M and Jayaram J 2005Decision Sciences2005,36,1:1
12Azithromycin for prevention of exacerbations in non-cystic fibrosis bronchiectasis(EMBRACE):a randomised,double-blind,placebo-controlled trial显示文摘Wong C Jayaram L Karalus N 2012Lancet2012,380,9842:1
13VADE: a virtual assembly design environment 显示文摘Jayaram S Jayaram U Wang Y 1999IEEE Computer Graphics and Applications1999,19,6:1
14Internal and exter- nal integration for product development: The contingency ef- fects of uncertainty, equivocality, and platform strategy 显示文摘Koufteros X Vonderembse M Jayaram J 2005Decision Sciences2005,36,1:1
15Measurement issues in the sonographic assessment of tennis elbow显示文摘Poltawski L Jayaram V Watson T 2010J Clin Ultrasound2010,38,4:1
16Capacitor placement in distribution systems using heuristic search'strategies 显示文摘M Chis M M A Salama S Jayaram 1997IEE Proceed- ings - Generation Transmission and Distribution1997,144,3:1
17Managing innovation in an emerging sector: the case of marine-based nutraceuticals 显示文摘Jayaram K Sankaran V Suchitra Mouly 2007R&D Management2007,37,4:1
18Steroid na? ve ec, sinophilie asthma: anti - inflanmaatory effects of fluticas- one and montelukast显示文摘Jayaram L Pizzichini E Lemiiere C 2005Thorax2005,60,2:1
19Causal linkages in supply chain management : an exploratory study of North American manufacturing firms 显示文摘Narasimhan R Jayaram J 1998Decision Sciences1998,29,3:1
20Internal and ex- ternal integration for product development: The contingency effects of uncertainty, equivocality, and platform strategy显示文摘Koufteros X Vonderembse M Jayaram J 2005Decision Sciences2005,36,1:1
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