|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Eosinophilic gastroenteritis:An unusual type of gastroenteritis显示文摘Eosinophilic gastroenteritis(EGE) is a rare disorder characterized by eosinophilic infiltration of the bowel wall with various gastrointestinal manifestations.Till date only 280 cases have been described in the literature.A high index of suspicion,by excluding other causes of peripheral eosinophilia,is a pre requisite for accurate diagnosis.EGE is an uncommon gastrointestinal disease affecting both children and adults.It was first described by Kaijser in 1937.Presentation may vary depending on location as well as depth and extent of bowel wall involvement and usually runs a chronic relapsing course.This condition can respond to low dose steroid therapy,thereby preventing grave complications like ascites and intestinal obstruction that might need surgical intervention.The natural history of EGE has not been well documented.Eosinophilic gastroenteritis is a chronic,waxing and waning condition.Mild and sporadic symptoms can be managed with reassurance and observation,whereas disabling gastrointestinal(GI) symptom flare-ups can often be controlled with oral corticosteroids.When the disease manifests in infancy and specific food sensitization can be identified,the likelihood of disease remission by late childhood is high.GI obstruction is the most common complication.Fatal outcomes are rare. | Sachin B Ingle Chitra R Hinge(Ingle) | 2013 | World Journal of Gastroenterology2013，19，31： | 47 |
| 2 | Primary intestinal lymphangiectasia: Minireview显示文摘Primary idiopathic intestinal lymphangiectasia is an unusual disease featured by the presence of dilated lymphatic channels which are located in the mucosa, submucosa or subserosa leading to protein loosing enteropathy.Most often affected were children and generally diagnosed before third year of life but may be rarely seen in adults too. Bilateral pitting oedema of lower limb is the main clinical manifestation mimicking the systemic disease and posing a real diagnostic dilemma to the clinicians to differentiate it from other common systemic diseases like Congestive cardiac failure, Nephrotic Syndrome, Protein Energy Malnutrition, etc. Diagnosis can be made on capsule endoscopy which can localise the lesion but unable to take biopsy samples. Thus, recently double-balloon enteroscopy and biopsy in combination can be used as an effective diagnostic tool to hit the correct diagnosis. Patients respond dramatically to diet constituting low long chain triglycerides and high protein content with supplements of medium chain triglyceride. So early diagnosis is important to prevent untoward complications related to disease or treatment for the sake of accurate pathological diagnosis. | Sachin B Ingle Chitra R Hinge(Ingle) | 2014 | World Journal of Clinical Cases2014，2，10： | 8 |
| 3 | Epithelial cysts of the spleen:A minireview显示文摘Primary splenic epithelial cyst is an unusual event in everyday surgical practice with about 800 cases reported until date in the English literature. Splenic cysts may be parasitic or non-parasitic in origin. Nonparasitic cysts are either primary or secondary. Primary cysts are also called true,congenital,epidermoid or epithelial cysts. Primary splenic cysts account for 10% of all benign non-parasitic splenic cysts and are the most frequent type of splenic cysts in children. Usually,splenic cysts are asymptomatic and can be found incidentally during imaging techniques or on laprotomy. The symptoms are related to the size of cysts. When they assume large sizes,they may present with fullness in the left abdomen,local or referred pain,symptoms due to compression of adjacent structures(like nausea,vomiting,flatulence,diarrhoea) or rarely thrombocytopenia,and occasionally complications such as infection,rupture and/or haemorrhage. The preoperative diagnosis of primary splenic cysts can be ascertained by ultrasonography(USG),computed tomography or magnetic resonance imaging,although the wide use of USG today has led to an increase in the incidence of splenic cysts by 1%. However,careful histopathological evaluation along with immunostaining for presence of epithelial lining is mandatory to arrive at the diagnosis. The treatment has changed drastically from total splenectomy in the past to splenic preservation methods recently. | Sachin B Ingle Chitra R Hinge (Ingle) Swapna Patrike | 2014 | World Journal of Gastroenterology2014，20，38： | 6 |
| 4 | Congenital pulmonary airway malformation: A report of two cases显示文摘Congenital pulmonary airway malformation(CPAM), previously known as congenital cystic adenomatoid malformation is a congenital disorder of the lung similar to bronchopulmonary sequestration. In CPAM, usually an entire lobe of lung is replaced by a non-working cystic piece of abnormal lung tissue. This abnormal tissue will never function as normal lung tissue. The underlying cause for CPAM is not known. It occurs in approximately 1 in every 30000 pregnancies. The association between CPAM and malignancy has been well documented. There is a small risk(0.7%) of malignant transformation within the cyst. So early diagnosis and surgical resection is important to prevent the grave complications. Herein, we are reporting two interesting cases of CPAM and one belonged to Type Ⅱ and other belonged to Type Ⅲ of Stocker's classification. | Saroj Bolde Smita Pudale Gopal Pandit Kirti Ruikar Sachin B Ingle | 2015 | World Journal of Clinical Cases2015，3，5： | 5 |
| 5 | Crohn's disease with gastroduodenal involvement: Diagnostic approach显示文摘Crohn's disease(CD) is a chronic idiopathic inflammatory disease of gastrointestinal tract characterizedby segmental and transmural involvement of gastrointestinal tract. Ileocolonic and colonic/anorectal is a most common and account for 40% of cases and involvement of small intestine is about 30%. Isolated involvement of stomach is an extremely unusual presentation of the disease accounting for less than 0.07% of all gastrointestinal CD. To date there are only a few documented case reports of adults with isolated gastric CD and no reports in the pediatric population. The diagnosis is difficult to establish in such cases with atypical presentation. In the absence of any other source of disease and in the presence of nonspecific upper gastrointestinal endoscopy and histological findings, serological testing can play a vital role in the diagnosis of atypical CD. Recent studies have suggested that perinuclear anti-neutrophil cytoplasmic antibody and anti-Saccharomycescervisia antibody may be used as additional diagnostic tools. The effectiveness of infliximab in isolated gastric CD is limited to only a few case reports of adult patients and the long-term outcome is unknown. | Sachin B Ingle Baban D Adgaonkar Nawab P Jamadar Saleha Siddiqui Chitra R Hinge | 2015 | World Journal of Clinical Cases2015，3，6： | 5 |
| 6 | Management of pregnancy in Crigler Najjar syndrome type 2显示文摘Crigler Najjar syndrome is associated with indirect hyperbilirubinemia due to a deficiency of enzyme Uridine Di Phospho Glucoronosyl Transferase(UDPGT).Presented here is a case of a female in the first trimester of pregnancy,who was diagnosed to have type 2 Crigler Najjar syndrome.We also discuss the management of this rare disease especially in pregnancy.Unconjugated bilirubin can cross the placental barrier causing neuro-logical damage in the newborn.Patient was carefully monitored during pregnancy and treatment with pheno-barbitone in low doses was adjusted such that the serum bilirubin levels were below 10 mg/d L.Crigler Najjar syndrome being rare needs to be diagnosed early in pregnancy to avoid adverse fetal outcomes.Phenobarbitone being an inducer of enzyme UDPGT is used as the first line of treatment and is not teratogenic in the low doses used.Treatment protocol followed was on the basis of previous reported cases and successful perinatal outcome was achieved. | Alisha Nitin Chaubal Ruchir Patel Dhaval Choksi Kaivan Shah Meghraj Ingle Prabha Sawant | 2016 | World Journal of Hepatology2016，8，11： | 4 |
| 7 | Splenic lymphoma with massive splenomegaly: Case report with review of literature显示文摘As per strict criteria of Das Gupta et al, primary splenic lymphoma is very rare. Herein, we are reporting an unusual case of primary large cell splenic lymphoma of B lineage in a middle aged female presenting with massive splenomegaly(3.8 kg) and hypersplenism. After performing therapeutic splenectomy for hypersplenism, a precise diagnosis of diffuse large B cell lymphoma was made on histopathology and confirmed by immunohistochemistry. The patient responded well to standard(Cyclophosphamide, Hydroxydaunorubicin, Oncovin(vincristine), Prednisone or prednisolone) regimen last year and is now in full remission. The splenectomy thereby has prevented the potential grave complications related to hypersplenism and splenic rupture. Our aim behind highlighting the topic is to specify that emergency splenectomy followed by anticoagulation therapy is an effective plan of management to prevent untoward complications related to disease and treatment. | Sachin B Ingle Chitra R Hinge Ingle | 2014 | World Journal of Clinical Cases2014，2，9： | 3 |
| 8 | Primary splenic lymphoma:Current diagnostic trends显示文摘The primary splenic lymphoma is extremely uncommon, can present with grave complications like hypersplenismand splenic rupture. In view of vague clinical presentation, it is difficult to arrive at the diagnosis. In such circumstances, histopathological diagnosis is very important. A precise diagnosis can only be made on histopathology and confirmed on immunohistochemistry.Emergency splenectomy is preferred as an effective therapeutic and diagnostic tool in cases with giant splenomegaly. Core biopsy is usually not advised due to a high risk of post-core biopsy complications in view of its high vascularity and fragility. Aim behind highlighting the topic is to specify that core biopsy/ fine needle aspiration cytology can be used as an effective diagnostic tool to arrive at correct diagnosis to prevent untoward complications related to disease and treatment. Anticoagulation therapy is vital after splenectomy to avoid portal splenic vein thrombosis. | Sachin B Ingle Chitra R Hinge(Ingle) | 2016 | World Journal of Clinical Cases2016，4，12： | 3 |
| 9 | Papillary carcinoma of breast: Minireview显示文摘The term 'intracystic papillary ductal carcinoma in situ ' constitutes only 0.5% to 1% of all breast cancers.It is usually seen in postmenopausal age group.Herein,we are presenting a minireview about this unusual breast malignancy usually difficult to diagnose on clinical grounds and highlighting modalities of diagnosis and management. | Sachin B Ingle Hemant G Murdeshwar Saleha Siddiqui | 2016 | World Journal of Clinical Cases2016，4，1： | 2 |
| 10 | Microscopic colitis: Common cause of unexplained nonbloody diarrhea显示文摘Microscopic colitis(MC) is characterized by chronic, watery, secretory diarrhea, with a normal or near normal gross appearance of the colonic mucosa. Biopsy is diagnostic and usually reveals either lymphocytic colitis or collagenous colitis. The symptoms of collagenous colitis appear most commonly in the sixth decade. Patients report watery, nonbloody diarrhea of a chronic, intermittent or chronic recurrent course. With collagenous colitis, the major microscopic characteristic is a thickened collagen layer beneath the colonic mucosa, and with lymphocytic colitis, an increased number of intraepithelial lymphocytes. Histological workup can confirm a diagnosis of MC and distinguish the two distinct histological forms, namely, collagenous and lymphocytic colitis. Presently, both forms are diagnosed and treated in the same way; thus, the description of the two forms is not of clinical value although this may change in the future. Since microscopic colitis was first described in 1976 and only recently recognized as a common cause of diarrhea, many practicing physicians may not be aware of this entity. In this review, we outline the epidemiology, risk factors associated with MC, its etiopathogenesis, the approach to diagnosis and the management of these individuals. | Sachin B Ingle Baban D Adgaonkar Chitra R Hinge(Ingle) | 2014 | World Journal of Gastrointestinal Pathophysiology2014，5，1： | 2 |
| 11 | Polymeric black tea polyphenols inhibit 1,2-dimethylhydrazine induced colorectal carcinogenesis by inhibiting cell proliferation via Wnt/β-catenin pathway显示文摘 | Rachana Patel Arvind Ingle Girish B. Maru | 2007 | Toxicology and Applied Pharmacology2007，，1： | 2 |
| 12 | Primary signet ring cell carcinoma of the appendix: A rare case report显示文摘Primary adenocarcinoma of the appendix is a rare malignancythat constitutes < 0.5% of all gastroin-testinalneoplasms. Moreover, primary signet ring cell carcinomaof the appendix is an exceedingly rare entity. In the present report, we describe a rare case of primary signet ring cell carcinoma of the appendix with ovarian metastasesand unresectable peritoneal dissemination occurring in a 45-year-old female patient. She was clinically misdiagnosed as torsion of ovarian cyst. She underwent appendicectomy and unilateral salpingooophorectomy.Histopathology revealed signet ring cell carcinoma and a right hemicolectomy was done. She then received palliative systemic chemotherapy with 12 cycles of oxaliplatin, 5-fluorouracil, and leucovorin(FOLFOX-4). The patient is doing well till today on follow up without progression of disease 10 mo after beginning chemotherapy. | Ram V Kulkarni Sachin B Ingle Saleha Siddiqui | 2015 | World Journal of Clinical Cases2015，3，6： | 2 |
| 13 | Extremely unusual case of gastrointestinal trichobezoar显示文摘Trichobezoars(hair ball) are usually located in the stomach, but may extend through the pylorus into the duodenum and small bowel(Rapunzel syndrome). Rapunzel syndrome remains uncommon; with fewer than 40 cases reported. To the best of our knowledge, this case may be the first well-documented case with a length of 75 cm. They are almost always associated with trichotillomania and trichophagia or other psychiatric disorders. In the literature several treatment options are proposed, including removal by conventional laparotomy, laparoscopy and endoscopy. Herein, we are reporting an interesting case of an 18-year mentally retarded girl with history of trichotillomania and trichophagia who presented to our emergency department with a history of central abdominal pain associated with vomiting and constipation for five days. An examination showed a trichobezoar requiring emergent surgical intervention, and indicating the need for psychiatric treatment. The trichobezoar was treated successfully by laparoscopy. | Sopan N Jatal Nawab P Jamadar Bhagwat Jadhav Saleha Siddiqui Sachin B Ingle | 2015 | World Journal of Clinical Cases2015，3，5： | 2 |
| 14 | 北阿拉伯海的光纤海洋观测网络:成功、挑战和机遇显示文摘2005年夏,一个先进的海洋观测网络——包括实时的光纤海洋观测系统和内部存储的自动化观测系统——被投放在了阿曼海和北阿拉伯海并运行至今。在2010年初,其中的自动化观测系统被升级到了新的深水光纤观测系统。这个海洋观测网络是在阿曼农业和渔业部的资助下,由美国的Lighthouse R&D公司设计、开发、安装和维护的。这2个观测系统作为一个整体已经连续工作了7年多的时间。所采集数据包括海流、温度、盐度、压力、溶解氧和浊度等。该海区是一个多水团的汇合区,波斯湾的高盐水和阿拉伯海的低盐水在这里汇合并蔓延南下到印度洋。对采集的数据研究表明,这一观测网络对研究该区域的物理和生物过程具有重要价值。在此,将系统介绍整个观测网络,并简要阐述已经完成和接近完成的4个研究主题:①对阿拉伯海有记载以来最强热带气旋'古怒'的海洋响应的研究;②阿曼海北部的季节性缺氧现象的季节及年际变化和成因分析;③深海声散射层的时空演变;④阿曼海和北阿拉伯海的高温高盐现象的成因。该观测网络采集的长期、连续的时间序列对这一地区的海洋动力研究、水文的季节性变化,以及气候的长期变化等研究都有很大帮助。此外,如果观测网络可以完成25年的设定观测目标,这将对验证和改进海洋环流模式和海气耦合模式具有重要意义。 | 王展坤 Steven DiMarco Stephanie Ingle Leila Belabbassi | 2013 | 地球科学进展2013，28，5： | 2 |
| 15 | Chilli Incidence and Effect on Seed Germ Ination 显示文摘 | ASALMOL M N KALE V P INGLE S T | 2001 | Seed Research2001，29，1： | 1 |
| 16 | Threshold for therapies: highlights of the Sankt Gallen international expert consensus on the primary therapy of early breast cancer 显示文摘 | Goldhirsch A Ingle JN Gelber RD | 2009 | Ann 0ncol2009，20，8： | 1 |
| 17 | Exemestane for breast-cancer prevention in postmenopausal women显示文摘 | Goss PE Ingle JN Ales-Martlnez JE | 2011 | N En- gl J Med2011，364，25： | 1 |
| 18 | Polyadenylation helps regulate mRNA decay in Escherichia coli 显示文摘 | O′Hara EB Chekanova JA Ingle CA | 1995 | Proc Natl Acad Sci USA1995，92，： | 1 |
| 19 | A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer 显示文摘 | Goss PE Ingle JN Martino S | 2003 | N Engl J Med2003，349，19： | 1 |
| 20 | Modem non-tropical mixed carbonate-siliciclastic sediments and environments of the southwestern Gulf of California, Mexico 显示文摘 | Halfar J Ingle J C Godinez-Orta L | 2004 | Sedimetary Geology2004，165，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员