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| 1 | Is rectal indomethacin effective in preventing of post-endoscopic retrograde cholangiopancreatography pancreatitis?显示文摘AIM:To investigate the effectiveness of rectally administered indomethacin in the prophylaxis of post-endoscopic retrograde cholangiopancreatography(ERCP)pancreatitis and hyperamylasaemia in a multicentre study.METHODS:A prospective,randomised,placebocontrolled multicentre study in five endoscopic units was conducted on 686 patients randomised to receive a suppository containing 100 mg indomethacin,or an inert placebo,10-15 min before ERCP.Post-ERCP pancreatitis and hyperamylasaemia were evaluated 24 h following the procedure on the basis of clinical signs and laboratory parameters,and computed tomography/magnetic resonance imaging findings if required.RESULTS:Twenty-one patients were excluded because of incompleteness of their data or because of protocol violation.The results of 665 investigations were evaluated:347 in the indomethacin group and 318 in the placebo group.The distributions of the risk factors in the two groups did not differ significantly.Pancreatitis developed in 42 patients(6.3%):it was mild in34(5.1%)and severe in eight(1.2%)cases.Hyperamylaesemia occurred in 160 patients(24.1%).There was no significant difference between the indomethacin and placebo groups in the incidence of either postERCP pancreatitis(5.8%vs 6.9%)or hyperamylasaemia(23.3%vs 24.8%).Similarly,subgroup analysis did not reveal any significant differences between the two groups.CONCLUSION:100 mg rectal indomethacin administered before ERCP did not prove effective in preventing post-ERCP pancreatitis. | Zoltán Dbrnte Zoltán Szepes Ferenc Izbéki Judit Gervain László Lakatos Gyula Pécsi Miklós Ihász Lilla Lakner Erzsébet Toldy László Czakó | 2014 | World Journal of Gastroenterology2014，20，29： | 16 |
| 2 | 25-羟维生素D和甲状旁腺激素与高血压的相关性显示文摘有研究证实,维生素D缺乏和甲状旁腺激素(PTH)过高与高血压的发生密切相关。维生素D缺乏不仅可以影响肾素血管紧张素系统及PTH水平,而且可以直接参与血管炎性反应,影响高血压的发生发展。PTH可以通过促进血管炎性反应及血管钙化等参与高血压的进展。目前还没有前瞻性研究同时评估维生素D和PTH水平与高血压发病的关系。该研究分析多民族动脉粥样硬化研究的前瞻性数据,发现低水平25羟维生素D[25(OH)D]和高水平PTH与高血压发病相关,特别是在肥胖人群中。但在校正混杂因素后,25(OH)D水平与高血压发病的相关性无统计学意义,而PTH水平与高血压发病仍然相关。鉴于维生素D缺乏和PTH过量在人群中是普遍现象,该研究对于更好地了解高血压发病机制,在人群中开展高血压预防工作有重要意义。 | van Ballegooijen AJ Kestenbaum B Sachs MC de Boer IH Siscovick DS Hoofnagle AN Ix JH Visser M Brouwer IA 练桂丽 叶鹏 | 2014 | 中华高血压杂志2014，22，6： | 10 |
| 3 | 高分辨力CT在间质性肺疾病诊断中的作用显示文摘重点论述高分辨力 CT 在诊断弥漫性肺疾病尤其是轻微病变中的价值,指出高分辨力 CT 对弥漫性肺疾病的特异性诊断优于胸片及其它影象学技术。 | Hansell DW Kerr IH 尉迟以浩 王彤 | 1992 | 国外医学(呼吸系统分册)1992，12，1： | 3 |
| 4 | Expression of matrix metalloproteinases and their inhibitors in human trabecular meshwork ceils 显示文摘 | Pang IH Hellberg PE Fleenor DL | 2003 | Invest Ophthalmol Vis Sci2003，44，8： | 1 |
| 5 | Human neural stern cells over-expressing VEGF provide neuroprotection, angiogenesis and functional recovery in mouse stroke model显示文摘 | Lee HJ Kim KS Park IH | 2007 | PLoS ONE2007，2，1： | 1 |
| 6 | Colorectal cancer: diagnostic potential of CT measurements of hepatic perfusion and implications for contrast enhancement protocols 显示文摘 | Kelley BB Bunce IH | 1997 | Radiology1997，205，3： | 1 |
| 7 | Application of NONMEM to routine bioavailability data显示文摘 | Chang IH | 1990 | J Pharmacokin Biopharm1990，18，2： | 1 |
| 8 | Problem_based learning:future challenges for educational practice and research显示文摘 | De Grave W Wolfhagen IH | 2005 | Med Educ2005，39，7： | 1 |
| 9 | Initial outcomc and efficacy of'kyphoplasty'in the trement of painful osteopolotic vertebral compression fractures显示文摘 | Dudeney S Reinhardt MK | 2001 | Spine2001，26，14： | 1 |
| 10 | Stem cell property of postmigratory cranial neural crest cells and their utility in alveolar bone regeneration and tooth development显示文摘 | Chung IH Yamaza T Zhao H | 2009 | Stem Cells2009，27，4： | 1 |
| 11 | Bright light treatment has limited effect in subjects over 55 years with mild early morning awakening显示文摘 | Pallesen S Nordhus IH Skelton SH | 2005 | Percept Mot Skills2005，101，3： | 1 |
| 12 | IL-23R polymorphisms in patients with ankylosing spondylitis in Korea显示文摘 | Sung IH Kim TH Bang SY | 2009 | J Rheumatol2009，36，5： | 1 |
| 13 | An evaluation of the quick inventory of depressive symptomatology and the hamilton rating scale for depression:a sequenced treatment alternatives to relieve depression trial report显示文摘 | Rush A J Bernstein IH Trivedi MH | 2006 | Biol Psychiatry2006，59，6： | 1 |
| 14 | Towards a physiological approach to breast cancer prevention 显示文摘 | Russo J Russo IH | 1994 | Cancer Epidemiot Biomarkers Prev1994，3，7： | 1 |
| 15 | hemodynamic conse-quences of rapid changes in posture in humans显示文摘 | Sheriff DD Ndland IH Toska K | 2007 | J ApplPhysiol2007，103，8： | 1 |
| 16 | Renoprotection by statins is linked to a decrease in renal oxidative stress, TGF-beta, and fibronectin with concomitant increase in nitric oxide bioavailability 显示文摘 | ZHOU MS SCHUMAN IH JAIMES EA | 2008 | Am J Physiol Renal Physiol2008，295，： | 1 |
| 17 | Radiological evaluation of benign breast disorders显示文摘 | Gravelle IH Yons K | 1989 | World J Surg1989，13，： | 1 |
| 18 | Quantitative relationship of the circulating tumor burden assessed by reverse transcriptionpolymerase chain reaction for cytokeratin 19 mRNA in peripheral blood of colorectal cancer patients with Dukes' stage, serum carcinoembryonic antigen level and tumor progression显示文摘 | Wong IH Yeo W Chan AT | 2001 | Cancer Lett2001，162，1： | 1 |
| 19 | B7-H4,a molecule of the B7 family, negatively regulates T cell immunity显示文摘 | Sica GL Choi IH Zhu G | 2003 | Immunity2003，18，6： | 1 |
| 20 | High - resolution CT of the pterygopalation fossa and its communications显示文摘 | Kim HS Kim DI Chung IH | 1996 | Neuroradiology1996，38，1： | 1 |
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