维普中文期刊产品整合服务
160篇 您的检索式:作者名="Igor S"
    题名 作者 年代 出处 被引量
1Effectiveness of repeated transplantations of hematopoietic stem cells in spinal cord injury显示文摘AIM: To evaluate the short and long-term effects of the complex cell therapy of 202 cases of spinal cord injury(SCI).METHODS: The main arm included 202 cases of SCI and the control arm included 20 SCI cases. For the therapy the hematopoietic stem cells(HSCs) and progenitor cells(PCs) were mobilized to peripheral blood by 8 subcutaneous injections of granulocyte colonystimulating factor(G-CSF) for 4 d and are harvested at day 5. The cells were administered to the main arm intrathecally every 3 mo for a long term(3-5 years) according to the internal research protocol international medical institute of tissue engineering. Magnetic resonance imaging of the site of injury and urodyna-mic tests were performed every 6 mo. Motor evoked potentials(MEP), somatosensory evoked potentials(SSEP) were evaluated every 3 mo. The patients were evaluated with american spianl injury association(ASIA) index, functional independence measure index, the Medical Research Council Scale, the International Standards for Neurological Classification of Spinal Cord Injury(ISCSCI-92) and specifically developed scales. The function of bladder was evaluated by a specifically developed clinical scale. The long-term clinical outcomes were assessed for the SCI patients who received no less than 20 intrathecal transplantations of HSCs and hematopoietic precursors(HPs).RESULTS: The restoration of neurologic deficit after HSCs and HPs transplantations was proved stable and evident in 57.4% of the cases. In 42.6% cases no neurologic improvement has been observed. In 50% of the cases the motor restoration began after the first transplantation, which is confirmed in average by 9.9 points improvement in neurologic impairment as compared to the baseline(P < 0.05). Repair of the urinary system was observed in 47.7% of the cases. The sensitivity improved from baseline 124.3 points to 138.4 after the first and to 153.5 points after the second transplantations of HSCs and HPs(P < 0.05, between the stages of research). The evaluation with ASIA index demonstrated regress of neurologic symptoms in 23 cases. Motor progress was also assessed with the ISCISCI-92 motor and sensory scores, and the data coincided with those received with the specifically developed scale. The number of the patients with the signs of locomotive repair was 56.9%. No life threatening complications or adverse effects have been observed.CONCLUSION: The method is safe, effective and considerably improves the life quality of SCI patients. The therapy is approved for clinical use as the treatment of choice.Andrey S Bryukhovetskiy Igor S Bryukhovetskiy 2015World Journal of Transplantation2015,5,3:4
2Biliary-colonic fistula caused by cholecystectomy bile duct injury显示文摘Biliary-colonic fistula is a rare complication after laparoscopic cholecystectomy. We present a case of post-cholecystectomy iatrogenic biliary injury that resulted in a fistula between the common hepatic duct and large bowel. Magnetic resonance cholangiopancreatography provided good visualization of injury even with concurrent normal level of alkaline phosphatase. Radiologic findings and surgical management of this condition are discussed in detail.Francisco Igor B Macedo Victor J Casillas James S Davis Joe U Levi Danny Sleeman 2013Hepatobiliary & Pancreatic Diseases International2013,12,4:2
3Simulation approach to decision assessment in enterprise 显示文摘Miroljub K Igor B Andrei S 2000Simulation2000,75,4:1
4Synthesis of glyeyrrhetinic acid deriva- tives for the treatment of metabolic diseases 显示文摘Igor B Laszlo C Priti S 2010Bioorg Med Chem2010,18,1:1
5Oral arginine reduces gut mucosal injury caused by lipopolysaccharide endotoxemia in rat 显示文摘IGOR S JORGE M 2004Journal of Surgical Research2004,122,2:1
6Botanical polysaccharides: Macrophage immunomedulation and therapeutic potential 显示文摘IGOR A S MARK T Q 2006Interna- tional Immunopharmacelogy2006,6,1:1
7Tracking-error model-based predictive control for mobile robots in real time 显示文摘GREGOR K IGOR S 2007Robotics and Autonomous System2007,55,6:1
8Comprehensive decision tree models in bioinformatics显示文摘Gregor S Simon K Igor P 2012PLoS One2012,7,3:1
9Nitrogen regulation of root branching显示文摘Pia W L Igor I Ivanov S F 2006Annals of Botany2006,97,5:1
10Measurement of Plasma and Intracellular S - Adenosylmethionine and S - Adenosylhomocysteine Utilizing Coulometric Electrochemical Detection: Alterations with Plasma Homocysteine and Pyridoxal 5'- Phosphate Concentrations 显示文摘Melnyk S Pogribna M Igor P 2000Clin Chem2000,46,:1
11Osmium isotope and highly siderophile element systematics of lunar impact melt breccias:Implications for the late accretion history of the Moon and Earth显示文摘Igor S Puchtel Richard Walker Odette B James Darid A Kring 2008Geochimica et Cosmochimica Acta2008,72,:1
12Stick-slip dynamics of a granular layer under shear显示文摘Volfson D Tsimring Lev S Aranson Igor S 2004Phys Rev E2004,69,:1
13Multiplex PCR for simultaneous detection of 677C→T and 1298A→C polymorphisms in methylenetetrahydrofolate reductase gene for population studies of cancer risk 显示文摘Ping Yi Igor P Pogribny S 2002Cancer letter2002,181,2:1
14Improving centrifugal pump efficiency by impeller trimming显示文摘Mario (S) Hrvoje K Igor S 0,,02:1
15Multivariable predictive functional control of an autoclave 显示文摘ALEKSANDER P IGOR S SASO B 2013Mechanical Engineering2013,59,2:1
16Halogenation of ketones with N- halosuecinimides under solvent-free reaction conditions显示文摘Igor P Marko Z Stojan S 2008Tetrahedron2008,64,:1
17Antibiofic resistance of en- terococciand related bacteria in an urban wastewater treat- ment plant显示文摘Miguel F S Igor T Anto' nio V 2006FEMS Microbiol Ecol2006,55,:1
18The effect of magnetic field on ion hydration and sulfate scale formation显示文摘Igor B Silva Joao C Queiroz Neto Denise F S Petri 2015Col- loids and Surfaces A: Physicochemical and Engineering Aspects2015,465,1:1
19A new strategy for the functiona- ization of aminofurazans: The synthesis of 3-R-furazan-4-yl) dichloroimines显示文摘Sheremetev Aleksei B Aleksandrova Natal'ya S irudin Igor L 2003Mendeleev 2ommun2003,13,:1
20Pathway redundancy and protein essentiality revealed in the Saccharomyces cerevisiae interaction networks显示文摘Igor U Ron S 2005Molecular Systems Biology2005,3,:1
返回顶部 每页显示:
共8页 首页 上一页 第1页 下一页 末页 /8 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费