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| 1 | 典型切削机床能耗模型的研究现状及发展趋势显示文摘机床作为机械制造行业的'母机',数量大、能耗高、效率低。近年来,学者们为建立精确的机床能耗模型已做大量工作。针对典型切削机床能耗的建模现状,从切削单元能耗、加工阶段整机能耗、工艺单元能耗三个层次进行综合分析。进而从节能优化、产品绿色性评估、企业资源配置、机床绿色设计四方面对机床能耗模型的应用进行论述。目前,机床能耗的建模逐渐面向高端数控机床,建模的目标性更加明确,与工业应用的结合也使得模型的实用价值不断提升。 | 李涛 孔露露 张洪潮 ASIF Iqbal | 2014 | 机械工程学报2014,50,7: | 40 |
| 2 | 尿钠排泄、血压、心血管病与死亡率的关系:社区前瞻性流行病学队列研究显示文摘WHO建议人群钠摄人<2 g/d作为预防心血管病的措施之一,但这一目标在任何国家都没有实现。该建议主要基于短期血压试验的个体水平数据,没有来自随机试验或观察性研究的关于低钠摄入与降低心血管事件的数据。前瞻性城市农村流行病学研究目前正在21个国家进行。该文对其中18个国家的数据进行分析,其中包含了临床结果数据。 | Mente A O'Donnell M Rangarajan S McQueen M Dagenais G Wielgosz A Lear S Ah STL Wei L Diaz R Avezum A Lopez-Jaramillo P Lanas F Mony P Szuba A Iqbal R Yusuf R Mohammadifard N Khatib R Yusoff K Ismail N Gulec S Rosengren A Yusufali A Kruger L Tsolekile LP Chifamba J Dans A Alhabib KF Yeates K Teo K Yusuf S 刘莉 叶鹏 | 2018 | 中华高血压杂志2018,26,12: | 29 |
| 3 | 高寒湿地和草甸退化及恢复对土壤微生物碳代谢功能多样性的影响显示文摘为研究高寒湿地、草甸的退化及恢复与土壤微生物碳代谢功能多样性的关系,以及影响土壤微生物碳代谢功能多样性的关键因素,利用BIOLOG Eco微平板法,分析了甘肃玛曲地区5类(湿地、沼泽化草甸、高寒草甸、退化草甸、人工恢复草甸) 14个退化与恢复样地的土壤微生物对单一碳源的利用情况。结果表明,从湿地到沙化草地的逐渐退化过程中,草甸的土壤微生物群落代谢活性差异显著;主要是由于在湿地干化过程中,微生物活性逐渐升高,沼泽草甸土壤微生物活性最高;随着草甸不断退化,微生物活性逐渐降低,沙化草地最低;而人工补播恢复使土壤微生物活性有所增加,表明退化对微生物碳代谢功能多样性造成显著影响,人工恢复措施在一定程度上提高了土壤微生物活性。聚合物类(吐温40、吐温80、环状糊精、肝糖)、氨基酸类及碳水化合物类是土壤微生物主要利用的碳源。冗余分析结果显示,土壤的碳氮比、含水量、有机碳、全氮、容重、氮磷比、p H及植被覆盖度是影响土壤微生物碳代谢功能多样性的关键因子。因此,可用土壤碳代谢功能多样性变化评价高寒湿地及草甸的退化和恢复及其变化程度。 | 李飞 刘振恒 贾甜华 李珊珊 白彦福 郭灿灿 王惟惟 孔猛 张涛 Awais Iqbal 周华坤 贾宇 尚占环 | 2018 | 生态学报2018,38,17: | 30 |
| 4 | Phytoremediation of heavy metal polluted soils and water:Progresses and perspectives显示文摘Environmental pollution affects the quality of pedosphere,hydrosphere,atmosphere,lithosphere and biosphere.Great efforts have been made in the last two decades to reduce pollution sources and remedy the polluted soil and water resources.Phytoremediation,being more cost-effective and fewer side effects than physical and chemical approaches,has gained increasing popularity in both academic and practical circles.More than 400 plant species have been identified to have potential for soil and water remediation.Among them,Thlaspi,Brassica,Sedum alfredii H.,and Arabidopsis species have been mostly studied.It is also expected that recent advances in biotechnology will play a promising role in the development of new hyperaccumulators by transferring metal hyperaccumulating genes from low biomass wild species to the higher biomass producing cultivated species in the times to come.This paper attempted to provide a brief review on recent progresses in research and practical applications of phytoremediation for soil and water resources. | Mohammad Iqbal LONE Zhen-li HE Peter J. STOFFELLA Xiao-e YANG | 2008 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2008,9,3: | 27 |
| 5 | Role of a probiotic (Saccharomyces boulardii) in management and prevention of diarrhoea显示文摘瞄准:估计酵母属 boulardii 的功效和安全(S。boulardii ) 在在减少腹泻的事件的频率在的尖锐水的腹泻和它的角色随后二个月。方法:从 2 瞬间的孩子到 12 岁,在 S 根据包括标准和随机的 ised 与尖锐腹泻被选择。boulardii 组(与 ORS,营养的支持和 S 一起对待。boulardii, 250 mg 出价) 并且在控制组(仅仅与 ORS 和营养的支持一起对待) 。直接疗法阶段是 5 d,每个孩子以后被跟随二个月。象药的安全一样的凳子的频率和一致性在每访问上被估计。二个组的比较以痢疾的事件的数字被做在随后二个月。结果:在每个组有五十个病人。象吝啬的年龄和凳子的平均频率那样的基线特征在 S 是可比较的。boulardii 和控制在试用在包括的时候组织。由 d 3 它分别地并且由 d 每 d 归结为 2.7 和 4.2 张凳子 6 它归结为 1.6 (S。boulardii 组) 并且 3.3 (控制组) 。腹泻的持续时间是在 S 的 3.6 d。而它是在控制组的 4.8 d, boulardii 组织(P = 0.001 ) 。在下列二个月内, S。有的 boulardii 组一显著地, 0.54 个事件的低频率作为与在控制的 1.08 个事件相比组织。这药很好被接受并且容忍。在治疗时期期间没有副作用的报告。结论:S。boulardii 显著地减少尖锐腹泻的频率和持续时间。凳子的一致性也改善。这药是容忍得好的。 | AG Billoo MA Memon SA Khaskheli G Murtaza Khalid Iqbal M Saeed Shekhani Ahson Q Siddiqi | 2006 | World Journal of Gastroenterology2006,12,28: | 22 |
| 6 | 青少年性相关知识来源的偏好:中国性教育的启示显示文摘目的:探讨分析15~24岁年龄段青少年性教育来源的偏好。方法:本研究所使用的数据来自于一项由世界卫生组织(WHO)资助的项目(WHO第98200号项目)。此项目是在中国东北某城市实施的基于社区为基础的横断面调查。住户样本的抽取采用按规模大小成比例的概率抽样原则,进行3阶段系统抽样设计。共有1319名15~24岁的青少年接受调查,并在参与调查前签署了知情同意书,参与者被告知自愿参加并有权退出调查和跳过其不愿回答的问题。最终有1227条记录进入分析阶段。运用描述性统计和多元Logistic回归分析方法对青少年获取性相关知识的来源偏好和实际获得知识的来源之间的差异进行分析。结果:青少年在过去实际使用的知识来源和其对来源的偏好方面存在差异。'父母','医生','书籍和报纸'和'电视'未能发挥青少年所预期的作用。青少年倾向于将'医生'作为获得'青春期'、'性知识'及'性传播疾病/艾滋病'等知识的主要渠道,而实际使用与来源偏好方面大概有10.2%~11.0%的差距。实际来自于父母对孩子的性教育则比偏好约低0.1%~2.7%。'书籍和报纸'和'电视'作为获得性相关知识的实际来源比偏好低3.3%~7.5%。多因素Logistic回归分析结果显示,年龄、性别、教育水平、工作经历和有无兄弟姐妹等因素影响青少年对获取性知识来源的偏好。20~24岁的男性更倾向于将'电视'作为其获取青春期知识的首选来源(回归系数=0.408,P<0.05),而女性则不倾向于将'电视'作为其首选来源去获取青春期知识、性知识和性传播疾病/艾滋病知识(回归系数分别为-1.305,-0.989和-0.653,P<0.05或P<0.01)。受过大学或研究生教育的被调查者不倾向将'老师'作为首选来源去获取青春期知识及性知识(回归系数分别为-0.544和-0.638,P<0.05)。相对于没有工作经历的被调查者,有工作经历的被调查者更倾向于将'同伴'作为获取有关'性传播疾病/艾滋病'知识的首选来源(回归系数=0.939,P<0.01)。女性更倾向于将'父母'作为首选知识来源获得青春期知识、性知识及性传播疾病/艾滋病知识(回归系数分别为1.649,1.449和1.110,P<0.01或P<0.05)。结论:现况调查表明中国青少年在实际获取性相关知识(即青春期知识,性知识,以及性传播疾病/艾滋病知识)的主要渠道与自己对获取性相关知识的来源偏好方面存在差异。书籍和报纸是青少年获取性相关知识中更喜欢选择的最主要来源,青少年也更喜欢从医生和父母那里得到性教育。目前研究的结果表明青少年不倾向于选择'老师'作为获取性相关知识来源,这为现在和将来的性教育干预方案提供了一些启示。父母和医生在未成年人和青少年性教育中的角色有待加强。学校课堂中,教师传授的性相关知识的内容及教学方法可能有待改善,而且需要学生们来进行评价。对于性教育中社会方面的积极作用,如媒体的作用不容忽视。综合的全方位的性教育需要进一步发展和强化,以满足青少年性知识和生殖健康方面的需要。 | 张立英 Iqbal H.Shah 李晓铭 尹文强 傅继华 夏志森 Bonita Stanton | 2010 | 国际生殖健康/计划生育杂志2010,29,6: | 22 |
| 7 | Biosorption characteristics of unicellular green alga Chlorella sorokiniana immobilized in loofa sponge for removal of Cr(Ⅲ)显示文摘Loofa sponge(LS)immobilized biomass of Chlorella sorokiniana(LSIBCS),isolated from industrial wastewater,was investigated as a new biosorbent for the removal of Cr(Ⅲ)from aqueous solution.A comparison of the biosorption of Cr(Ⅲ)by LSIBCS and free biomass of C.sorokiniana(FBCS)from 10-300 mg Cr(Ⅲ)/L aqueous solutions showed an increase in uptake of 17.79% when the rnicroalgal biomass was immobilized onto loofa sponge.Maximum biosorption capacity for LSIBCS and FBCS was found to be 69.26 and 58.80 mg Cr(Ⅲ)/g biosorbent,respectively,whereas the amount of Cr(Ⅲ)ions adsorbed onto naked LS was 4.97 mg/g.The kinetics of Cr(Ⅲ)biosorption was extremely rapid and equilibrium was established in about 15 and 20 min by LSIBCS and FBCS, respectively.The biosorption equilibrium was well defined by Langrnuir adsorption isotherm model.The biosorption kinetics followed the pseudo-second order kinetic model.The biosorption was found to be pH dependent and the maximum sorption occurred at the solution pH 4.0.Desorption studies showed that 98% of the adsorbed Cr(Ⅲ)could be desorbed with 0.1 mol/L HNO_3,while other desorbing agents were less effective in the order:EDTA>H_2SO_4>CH_3COOH>HCl.The regenerated LSIBCS retained 92.68% of the initial Cr(Ⅲ)binding capacity up to five cycles of reuse in continuous flow-fixed bed columns.The study revealed that LSIBCS could be used as an effective biosorbent for the removal of Cr(Ⅲ)from wastewater. | AKHTAR Nasreen IQBAL Muhammad ZAFAR Saeed Iqbal IQBAL Javed | 2008 | Journal of Environmental Sciences2008,20,2: | 20 |
| 8 | 山银花化学成分与其生物活性的研究进展(英文)显示文摘山银花作为中国传统中药,在中国有数千年历史。目前,山银花在湖南省有广泛栽培,主要作为清热药和消毒药应用。山银花主要包括咖啡酸衍生物、挥发油、黄酮类化合物、环烯醚萜苷和萜类化合物,主要有抗炎、抗肿瘤、抗氧化、抗过敏、免疫调节及抗菌活性等。本文通过查阅相关文献,对山银花的化学成分及其生物活性进行了全面的系统总结。 | 汤嫣然 曾婷 Salman zafar 袁汉文 李斌 彭彩云 王思成 翦雨青 覃艳 Muhammad Iqbal Choudhary 王炜 | 2018 | Digital Chinese Medicine2018,1,2: | 17 |
| 9 | Crop photosynthetic response to light quality and light intensity显示文摘Under natural conditions, plants constantly encounter various biotic and abiotic factors, which can potentially restrict plant growth and development and even limit crop productivity. Among various abiotic factors affecting plant photosynthesis, light serves as an important factor that drives carbon metabolism in plants and supports life on earth. The two components of light(light quality and light intensity) greatly affect plant photosynthesis and other plant's morphological, physiological and biochemical parameters. The response of plants to different spectral radiations and intensities differs in various species and also depends on growing conditions. To date, much research has been conducted regarding how different spectral radiations of varying intensity can affect plant growth and development. This review is an effort to briefly summarize the available information on the effects of light components on various plant parameters such as stem and leaf morphology and anatomy, stomatal development, photosynthetic apparatus, pigment composition, reactive oxygen species(ROS) production, antioxidants, and hormone production. | Iram SHAFIQ Sajad HUSSAIN Muhammad Ali RAZA Nasir IQBAL Muhammad Ahsan ASGHAR Ali RAZA FAN Yuan-fang Maryam MUMTAZ Muhammad SHOAIB Muhammad ANSAR Abdul MANAF YANG Wen-yu YANG Feng | 2021 | Journal of Integrative Agriculture2021,20,1: | 16 |
| 10 | Landslide susceptibility mapping using an integrated model of information value method and logistic regression in the Bailongjiang watershed,Gansu Province,China显示文摘Bailongjiang watershed in southern Gansu province, China, is one of the most landslide-prone regions in China, characterized by very high frequency of landslide occurrence. In order to predict the landslide occurrence, a comprehensive map of landslide susceptibility is required which may be significantly helpful in reducing loss of property and human life. In this study, an integrated model of information value method and logistic regression is proposed by using their merits at maximum and overcoming their weaknesses, which may enhance precision and accuracy of landslide susceptibility assessment. A detailed and reliable landslide inventory with 1587 landslides was prepared and randomly divided into two groups,(i) training dataset and(ii) testing dataset. Eight distinct landslide conditioning factors including lithology, slope gradient, aspect, elevation, distance to drainages,distance to faults, distance to roads and vegetation coverage were selected for landslide susceptibility mapping. The produced landslide susceptibility maps were validated by the success rate and prediction rate curves. The validation results show that the success rate and the prediction rate of the integrated model are 81.7 % and 84.6 %, respectively, which indicate that the proposed integrated method is reliable to produce an accurate landslide susceptibility map and the results may be used for landslides management and mitigation. | DU Guo-liang ZHANG Yong-shuang IQBAL Javed YANG Zhi-hua YAO Xin | 2017 | Journal of Mountain Science2017,14,2: | 16 |
| 11 | 趋化性细胞因子受体CXCR4在大肠癌的表达及其临床意义显示文摘目的:探讨趋化性细胞因子受体CXCR4在大肠癌中的表达及其与预后的关系.方法:收集67例大肠癌患者手术标本,采用免疫组织化学方法检测肿瘤组织中CXCR4蛋白的表达和微血管密度,分析CXCR4的表达水平与临床病理特征和生存的关系.结果:大肠癌组织中CXCR4蛋白表达阳性率为56.7%(38/67),与患者的性别、年龄、肿瘤部位、T分期和病理类型无相关性(P>0.05),与淋巴结转移、临床分期、微血管密及生存相关.N0,N1和N2期CXCR4的阳性率分别为40.6%,68.2%,76.9%(P<0.05);Ⅰ+Ⅱ期和Ⅲ期CXCR4的阳性率分别为39.4%,73.5%(P<0.05).低MVD组CXCR4的阳性率显著低于高MVD组(36.4%vs74.3%,P<0.01);CXCR4阳性组较CXCR4阴性组有较高的复发/转移率(47.4%vs24.1%,P<0.05)和较低的3a无病生存率(32.6%vs71.3%,P<0.05).结论:CXCR4可能促进大肠癌的侵袭和转移以及血管生成并影响其预后. | 张孟贤 Kashif Iqbal 于世英 | 2007 | 世界华人消化杂志2007,15,7: | 13 |
| 12 | Survey of intrusion detection systems:techniques,datasets and challenges显示文摘Cyber-attacks are becoming more sophisticated and thereby presenting increasing challenges in accurately detecting intrusions.Failure to prevent the intrusions could degrade the credibility of security services,e.g.data confidentiality,integrity,and availability.Numerous intrusion detection methods have been proposed in the literature to tackle computer security threats,which can be broadly classified into Signature-based Intrusion Detection Systems(SIDS)and Anomaly-based Intrusion Detection Systems(AIDS).This survey paper presents a taxonomy of contemporary IDS,a comprehensive review of notable recent works,and an overview of the datasets commonly used for evaluation purposes.It also presents evasion techniques used by attackers to avoid detection and discusses future research challenges to counter such techniques so as to make computer systems more secure. | Ansam Khraisat Iqbal Gondal Peter Vamplew Joarder Kamruzzaman | 2019 | Cybersecurity2019,2,1: | 13 |
| 13 | Increased hepcidin expression in colorectal carcinogenesis显示文摘AIM:To investigate whether the iron stores regulator hepcidin is implicated in colon cancer-associated anae- mia and whether it might have a role in colorectal car- cinogenesis. METHODS: Mass spectrometry (MALDI-TOF MS and SELDI-TOF MS) was employed to measure hepcidin in urine collected from 56 patients with colorectal cancer. Quantitative Real Time RT-PCR was utilised to determine hepcidin mRNA expression in colorectal cancer tissue. Hepcidin cellular localisation was determined using im- munohistochemistry. RESULTS: We demonstrate that whilst urinary hepcidin expression was not correlated with anaemia it was posi- tively associated with increasing T-stage of colorectal cancer (P < 0.05). Furthermore, we report that hepcidin mRNA is expressed in 34% of colorectal cancer tissue specimens and was correlated with ferroportin repres- sion. This was supported by hepcidin immunoreactivity in colorectal cancer tissue. CONCLUSION: We demonstrate that systemic hepcidin expression is unlikely to be the cause of the systemic anaemia associated with colorectal cancer. However, we demonstrate for the first time that hepcidin is expressed by colorectal cancer tissue and that this may represent a novel oncogenic signalling mechanism. | Douglas G Ward Keith Roberts Matthew J Brookes Howard Joy Ashley Martin Tariq Ismail Robert Spychal Tariq Iqbal Chris Tselepis | 2008 | World Journal of Gastroenterology2008,14,9: | 12 |
| 14 | Methane hydrate formation and dissociation in synthetic seawater显示文摘The formation and dissociation of methane gas hydrate at an interface between synthetic seawater (SSW) and methane gas have been experimentally investigated in the present work. The amount of gas consumed during hydrate formation has been calculated using the real gas equation. Induction time for the formation of hydrate is found to depend on the degree of subcooling. All the experiments were conducted in quiescent system with initial cell pressure of 11.14 MPa. Salinity effects on the onset pressure and temperature of hydrate formation are also observed. The dissociation enthalpies of methane hydrate in synthetic seawater were determined by Clausius-Clapeyron equation based on the measured phase equilibrium data. The dissociation data have been analyzed by existing models and compared with the reported data. | Vikash Kumar Saw Iqbal Ahmad Ajay Mandal G.Udayabhanu Sukumar Laik | 2012 | Journal of Natural Gas Chemistry2012,21,6: | 12 |
| 15 | Impact of on-range choice feeding with black soldier fly larvae(Hermetia illucens)on flock performance,egg quality,and range use of free-range laying hens显示文摘Semi-intensive free-range farm systems are common in Australia, and these systems frequently practise on-range feeding. The objective of this study was to investigate the benefit of on-range choice feeding on flock performance, egg quality, and range use of free-range laying hens using black soldier fly larvae(Hermetia illucens, BSF). A total of 160 mature ISA brown laying hens, previously determined to range daily, were allocated to a control group(control) or a treatment group(BSF) with various replicates depending on the parameter investigated. All hens were fed ad libitum indoors with a wheat-soy based diet formulated according to breed requirements. Black soldier fly hens were offered dried BSF larvae ad libitum on the range. Body weight, feed intake, BSF intake, egg production, feed conversion ratio, internal and external egg quality parameters, and individual range use using radio-frequency identification(RFID)technology was evaluated. Black soldier fly hens consumed on average 15 ± 1.7 g BSF larvae/hen per day.There were no differences between BSF and control hens for any of the performance parameters obtained(P > 0.05). Egg weight, shell weight, and shell thickness of eggs from BSF hens were significantly lower(P = 0.003, P = 0.001, and P = 0.004, respectively) than those of eggs from control hens. Egg yolk colour was significantly paler in eggs from BSF hens(P < 0.001). No significant ranging differences between the BSF and control hens were observed(P > 0.05) except for BSF hens showing longer total maximum time for a single visit to the range(P = 0.011). In conclusion, the average intake of BSF larvae indicated a good level of acceptance. Feed formulation should be adjusted for the intake of the choice fed source. The impact of choice-feeding on range use was minor. | Isabelle Ruhnke Camille Normant Dana L.M.Campbell Zafar Iqbal Caroline Lee Geoff N.Hinch Julie Roberts | 2018 | Animal Nutrition2018,,4: | 12 |
| 16 | Comparative analysis of the complete chloroplast genome among Prunus mume,P.armeniaca,and P.salicina显示文摘Prunus mume Sieb.et Zucc.,P.armeniaca L.,and P.salicina L.are economically important fruit trees in temperate regions.These species are taxonomically perplexing because of shared interspecific morphological traits and variation,which are mainly attributed to hybridization.The chloroplast is cytoplasmically inherited and often used for evolutionary studies.We sequenced the complete chloroplast genomes of P.mume,P.armeniaca,and P.salicina using Illumina sequencing followed by de novo assembly.The three chloroplast genomes exhibit a typical quadripartite structure with conserved genome arrangement,structure,and moderate divergence.The lengths of the genomes are 157,815,157,797,and 157,916 bp,respectively.The length of the large single-copy region(LSC)region is 86,113,86,283,and 86,122 bp,and the length of the SSC region is 18,916,18,734,and 19,028 bp;the IR region is 26,393,26,390,and 26,383 bp,respectively.Each of the three chloroplast genomes encodes 133 genes,including 94 protein-coding,31 tRNA,and eight rRNA genes.Differential gene analysis for the three species revealed that trnY-ATA is a unique gene in P.armeniaca;in contrast,the gene trnI-TAT is only present in P.mume and P.salicina,though the position of the gene in these chloroplast genomes differs.Further comparative analysis of the complete chloroplast genome sequences revealed that the ORF genes and the sequences of linked regions rps16 and atpA,atpH and atpI,trnc-GCA and psbD,ycf3 and atpB,and rpL32 and ndhD are significantly different and may be used as molecular markers in taxonomic studies.Phylogenetic evolution analysis of the three species suggests that P.mume has a closer genetic relationship to P.armeniaca than to P.salicina. | Song Xue Ting Shi Wenjie Luo Xiaopeng Ni Shahid Iqbal Zhaojun Ni Xiao Huang Dan Yao Zhijun Shen Zhihong Gao | 2019 | Horticulture Research2019,6,1: | 10 |
| 17 | Long-term Activity of Earthquake-induced Landslides: A Case Study from Qionghai Lake basin, Southwest of China显示文摘Earthquake-triggered landslides are a major geological hazard in the eastern Tibetan Plateau, and have prolonged impact on earth surface processes and fluvial system. To determine how long co-seismic landslides affect basins, a massive number of landslides existing in Qionghai Lake Basin were investigated for landslide distribution characteristics and geomorphological evidences, with further comparison and analysis using historic seismic analog method. The landslides found in Qionghai Lake Basin showed clear features of seismic triggering with strongly controlled by Zemuhe fault. These landslides are still active at present. Some new slides generally occur in ancient slope failure zones causing serious secondary hazards in recent years. In this study we strengthen the idea that the landslides triggered by the 1850 Xichang earthquake(MS7.5) have long term activity and prolonged impact on the mountain disasters with a period of more than 160 years. Our results support growing evidence that co-seismic landslides have a prolonged effect on secondary disasters in a basin, and invite more careful consideration of the relationship between current basin condition and landslide history for a longer period. | WEI Xue-li CHEN Ning-sheng CHENG Qian-gong HE Na DENG Ming-feng TANOLI Javed Iqbal | 2014 | Journal of Mountain Science2014,11,3: | 9 |
| 18 | In vitro total phenolics,flavonoids contents and antioxidant activity of essential oil,various organic extracts from the leaves of tropical medicinal plant Tetrastigma from Sabah显示文摘Objective:To detect the in vitro total phenolics,flavonoids contents and antioxidant activity of essential oil,various organic extracts from the leaves of tropical medicinal plant Tetrastigma from Sabah.Methods:The dry powder leaves of Tetrastigma were extracted with different organic solvent such as hexane.ethyl acetate,chloroform,butanol and aqueous methanol.The total phenolic and total flavonoids contents of the essential oil and various organic extracts such as hexane,ethyl acetate,chloroform,butanol and aqueous ethanol were determined by Folin-Ciocalteu method and the assayed antioxidant activity was determined in vitro models such as antioxidant capacity by radical scavenging activity usingα,α-diphenyl-β-picrylhydrazyl (DPPH) method.Results:The total phenolic contents of the essential oil and different extracts as gallic acid equivalents were found to be highest in methanol extract(386.22 mg/g) followed by ethyl acetate(190.89 mg/g).chloroform(175.89 mg/g).hexane(173.44 mg/g).and Imtanol extract (131.72 mg/g) and the phenolic contents not detected in essential oil.The antioxidant capacity of the essential oil and different extracts as ascorbic acid standard was in the order of methanol extract>ethyl acetate extract>chloroform>butanol>hexane extract also the antioxidant activity was not detected in essential oil.Conclusions:The findings show that the extent of antioxidant activity of the essential oil and all extracts are in accordance with the amount of phenolics present in that extract.Leaves of Tetrastigma being rich in phenolics may provide a good source of antioxidant. | M Amzad Hossain Muhammad Dawood Shah Charles Gnanaraj Muhammad Iqbal | 2011 | Asian Pacific Journal of Tropical Medicine2011,4,9: | 9 |
| 19 | Plant-derived anticancer agents: A green anticancer approach显示文摘Cancer is a frightful disease and represents one of the biggest health-care issues for the human race and demands a proactive strategy for cure. Plants are reservoirs for novel chemical entities and provide a promising line for research on cancer. Hitherto, being effective, chemotherapy is accompanied by certain unbearable side effects. Nevertheless,plants and plant derived products is a revolutionizing field as these are Simple, safer, ecofriendly, low-cost, fast, and less toxic as compared with conventional treatment methods.Phytochemicals are selective in their functions and acts specifically on tumor cells without affecting normal cells. Carcinogenesis is complex phenomena that involves many signaling cascades. Phytochemicals are considered suitable candidates for anticancer drug development due to their pleiotropic actions on target events with multiple manners. The research is in progress for developing potential candidates(those can block or slow down the growth of cancer cells without any side effects) from these phytochemicals. Many phytochemicals and their derived analogs have been identified as potential candidates for anticancer therapy. Effort has been made through this comprehensive review to highlight the recent developments and milestones achieved in cancer therapies using phytomolecules with their mechanism of action on nuclear and cellular factors. Furthermore, drugs for cancer treatment and their limitations have also been discussed. | Javed Iqbal Banzeer Ahsan Abbasi Tariq Mahmood Sobia Kanwal Barkat Ali Sayed Afzal Shah Ali Talha Khalil | 2017 | Asian Pacific Journal of Tropical Biomedicine2017,7,12: | 8 |
| 20 | Photosynthesis, Growth and Antioxidant Metabolism in Mustard (Brassica juncea L.) Cultivars Differing in Cadmium Tolerance显示文摘Two mustard (Brassica juncea L. Czern and Coss.) cultivars, Pusa Jai Kisan and SS2 differing in cadmium (Cd) tolerance were treated with 0, 25 and 50 μmol L-1 Cd to study the physiological basis of difference in Cd tolerance. Cultivar SS2 (Cd sensitive) accumulated greater Cd in leaves than Pusa Jai Kisan (Cd tolerant). Further, SS2 also exhibited higher contents of thiobarbituric acid reactive substances (TBARS) and H2O2 and electrolyte leakage. However, the activities of antioxidant enzymes, catalase (CAT), ascorbate peroxidase (APX), dehydroascorbate reductase (DHAR), and glutathione reductase (GR) were higher in Pusa Jai Kisan than those in SS2. Contrarily, the activity of superoxide dismutase (SOD) was higher in SS2 than that in Pusa Jai Kisan and was the greatest at 25 μmol L-1 Cd. Treatment of 25 μmol L-1 Cd induced the maximum activity of enzymes. However, the activity of GR increased up to 50 μmol L-1 Cd in both the cultivars. The non-enzymatic antioxidants ascorbate (AsA) and glutathione (GSH) were higher in Pusa Jai Kisan than that in SS2, whereas dehydroascorbate (DHA) and oxidized glutathione (GSSG) were higher in SS2. Photosynthesis and growth were adversely and maximally decreased by 50 μmol L-1 Cd treatment in both the cultivars, but SS2 exhibited greater reductions. The protection of photosynthesis and growth and lesser reduction in Pusa Jai Kisan were associated with its capacity to restrict accumulation of Cd in leaves resulting in lower level of TBARS and H2O2 and electrolyte leakage. Moreover, Pusa Jai Kisan exhibited efficient antioxidant metabolism for removal of Cd-induced reactive oxygen species. | Noushina Iqbal Asim Masood Rahat Nazar Shabina Syeed Nafees A Khan | 2010 | Agricultural Sciences in China2010,9,4: | 8 |