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| 1 | Role of wireless capsule endoscopy in the follow-up of inflammatory bowel disease显示文摘The introduction of wireless capsule endoscopy in 2000 has revolutionized our ability to visualize parts of the small bowel mucosa classically unreached by the conventional endoscope, and since the recent introduction of colon capsule endoscopy, a promising alternative method has been available for the evaluation of large bowel mucosa. The advantages of wireless capsule endoscopy include its non-invasive character and its ability to visualize proximal and distal parts of the intestine, while important disadvantages include the procedure's inability of tissue sampling and significant incompletion rate. Its greatest limitation is the prohibited use in cases of known or suspected stenosis of the intestinal lumen due to high risk of retention. Wireless capsule endoscopy plays an important role in the early recognition of recurrence, on Crohn's disease patients who have undergone ileocolonic resection for the treatment of Crohn's disease complications, and in patients' management and therapeutic strategy planning, before obvious clinical and laboratory relapse. Although capsule endoscopy cannot replace traditional endoscopy, it offers valuable information on the evaluation of intestinal disease and has a significant impact on disease reclassification of patients with a previous diagnosis of ulcerative colitis or inflammatory bowel disease unclassified/indeterminate colitis. Moreover, it may serve as an effective alternative where colonoscopy is contraindicated and in cases with incomplete colonoscopy studies. The use of patency capsule maximizes safety and is advocated in cases of suspected small or large bowel stenosis. | Ioannis V Mitselos Dimitrios K Christodoulou Konstantinos H Katsanos Epameinondas V Tsianos | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，6： | 4 |
| 2 | Circulating autoantibodies to endogenous erythropoietin are associated with chronic hepatitis C virus infection-related anemia显示文摘BACKGROUND: Chronic hepatitis C virus(HCV) infection is associated with autoimmune phenomena and is often complicated by anemia. Circulating autoantibodies to endogenous erythropoietin(anti-EPO) have been detected in patients with chronic viral infections and were correlated to anemia. The present study aimed to determine anti-EPO prevalence in patients with chronic HCV infection and investigate its possible association with anemia.METHODS: Ninety-three consecutive patients(62 males and 31 females) with chronic HCV infection, who had never received antiviral therapy or recombinant EPO, were enrolled in the study. Circulating anti-EPO were detected in the serum by using an ELISA assay. Quantitative determination of serum EPO levels was done by radioimmunoassay. HCV RNA viral load measurement and genotype sequencing were also performed.RESULTS: Circulating anti-EPO were detected in 10.8% of HCV-infected patients and the prevalence of anti-EPO was significantly higher in patients with anemia(19.4% vs 5.3%, P=0.040) compared to that in those without anemia. Compared to anti-EPO negative cases, anti-EPO positive patients had higher frequency of anemia(70.0% vs 34.9%, P=0.030), lower EPO concentrations(median 16.35 vs 30.65 m U/m L, P=0.005), and higher HCV RNA viral load(median 891.5×103 vs 367.5×103 IU/m L, P=0.016). In multivariate regression analysis the presence of anti-EPO remained an independent predictor of anemia(adjusted OR: 14.303, 95% CI: 1.417-36.580, P=0.024). EPO response to anemia was less prominent among anti-EPO positive patients(P=0.001).CONCLUSIONS: Circulating anti-EPO are detected in a significant proportion of treatment-na?ve HCV-infected patients and are independently associated with anemia, suggesting a further implication of autoimmunity in the pathophysiology of HCV-related anemia. | Aristotelis Tsiakalos Theoharis Voumvas Alexandros Psarris Christina K Oikonomou Dimitrios C Ziogas Ioannis Ketikoglou Grigorios Hatzis Nikolaos V Sipsas | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，3： | 4 |
| 3 | Restless legs syndrome is contributing to fatigue and low quality of life levels in hemodialysis patients显示文摘AIM To examine whether hemodialysis(HD) patients with restless legs syndrome(RLS) are subjects of greater fatigue and impaired quality of life(QoL) compared to HD patients without RLS.METHODS Eighty five stable HD patients participated in this study. According to their RLS status, the patients were dividedinto the RLS group(n = 23) and the non-RLS group(n = 62). QoL, fatigue, sleep quality, daily sleepiness and depression symptoms were assessed by using various questionnaires. Finally, biochemical parameters including iron, ferritin, hemoglobin, hematocrit and parathormone were assessed. RESULTS The HD patients with RLS scored worse in all the questionnaires used in the study(P < 0.05). The patients with RLS were more likely to receive the HD therapy on the morning shift, whilst 43.5% of the RLS patients reported to experience the RLS symptoms also during HD. The severity of RLS was correlated with fatigue, depression score and sleep quality(P < 0.05). CONCLUSION HD patients with RLS are subject to lower QoL related parameters and greater fatigue compared to HD patients without RLS. RLS should be successfully managed in order to improve the QoL of the sufferers. | Christoforos D Giannaki Michael Hadjigavriel Akis Lazarou Aristos Michael Loukas Damianou Efthimios Atmatzidis Ioannis Stefanidis Georgios M Hadjigeorgiou Giorgos K Sakkas Marios Pantzaris | 2017 | World Journal of Nephrology2017，6，5： | 3 |
| 4 | TiO 2 -assisted photocatalytic degradation of azo dyes in aqueous solution: kinetic and mechanistic investigations显示文摘 | Ioannis K Konstantinou Triantafyllos A Albanis | 2003 | Applied Catalysis B, Environmental2003，，1： | 2 |
| 5 | COVID-19 and liver injury: An ongoing challenge显示文摘The new coronavirus severe acute respiratory syndrome coronavirus 2(SARSCoV-2)was identified in December 2019,in Wuhan,China.The virus was rapidly spread worldwide,causing coronavirus disease 2019(COVID-19)pandemic.Although COVID-19 is presented,usually,with typical respiratory symptoms(i.e.,dyspnea,cough)and fever,extrapulmonary manifestations are also encountered.Liver injury is a common feature in patients with COVID-19 and ranges from mild and temporary elevation of liver enzymes to severe liver injury and,even,acute liver failure.The pathogenesis of liver damage is not clearly defined;multiple mechanisms contribute to liver disorder,including direct cytopathic viral effect,cytokine storm and immune-mediated hepatitis,hypoxic injury,and druginduced liver toxicity.Patients with underlying chronic liver disease(i.e.,cirrhosis,non-alcoholic fatty liver disease,alcohol-related liver disease,hepatocellular carcinoma,etc.)may have greater risk to develop both severe COVID-19 and further liver deterioration,and,as a consequence,certain issues should be considered during disease management.The aim of this review is to present the prevalence,clinical manifestation and pathophysiological mechanisms of liver injury in patients with SARS-CoV-2 infection.Moreover,we overview the association between chronic liver disease and SARS-CoV-2 infection and we briefly discuss the management of liver injury during COVID-19. | Ioanna Papagiouvanni Serafeim-Chrysovalantis Kotoulas Athanasia Pataka Dionisios G Spyratos Konstantinos Porpodis Afroditi K Boutou Georgios Papagiouvannis Ioanna Grigoriou Christos Vettas Ioannis Goulis | 2023 | World Journal of Gastroenterology2023，29，2： | 2 |
| 6 | Pore-network study of the characteristic periods in the drying of porous materials显示文摘 | Yiotis Andreas G Tsimpanogiannis Ioannis N Stubos A K | | 0，，02： | 1 |
| 7 | Photodegradation of selected herbicides in various natural waters and soils under environmental conditions显示文摘 | Ioannis K K Antonios K Z Triantafyllos A A | 2001 | Journal of Environmental Quality2001，30，： | 1 |
| 8 | Rapid synthesis of 2, 3-disubstituted-quinazolin-4-ones enhanced by micro- wave-assisted decomposition of formamide 显示文摘 | Ioannis K Abdelhakim E Elisabeth S | 2007 | Tetrahedron Lett2007，48，： | 1 |
| 9 | Evolutionary Al- gorithm Based Offline/Online Path Planner for UAV Navigation显示文摘 | Ioannis K Nikolos Kimon P Valavanis | 2003 | IEEE TRANSACTIONS ON SYSTEMS MAN AND CYBERNETICS-PART B: CYBERNETICS2003，33，6： | 1 |
| 10 | Spontaneous perirenal hemorrhage: A 10-year experience at our institution显示文摘 | GEORGE D I OANNIS K IOANNIS H | 2004 | International Urology and Nephrolagy2004，36，： | 1 |
| 11 | Convergence Rates for Inexact Newton - like Methods at Singular Points and Applications显示文摘 | ARGYROS Ioannis K | 1999 | Applied Mathematics and Computation1999，102，： | 1 |
| 12 | Photocatalytic transformation of pesticides in aqueous titanium dioxide suspensions using ar- tificial and solar light: intermediates and degradation path- ways 显示文摘 | Ioannis K Triantaf~cllos A | 2003 | Applied Catalysis2003，42，5： | 1 |
| 13 | The expression of vascular endothelial growth factor-C correlates with lymphatic micmvessel density and lymph node metastasis in prostate carcinoma: An im- munohistochemical study显示文摘 | Kestis G Ioannis L Helen K | 2014 | Uml Ann2014，6，3： | 1 |
| 14 | Conjugated estrogen administration improves common carotid artery elastic properties in normotensive postmenopausal women 显示文摘 | Ioannis K Costas T Panaglotis Z | 2002 | Clinical Cardiology2002，25，： | 1 |
| 15 | Use of treated municipal wastewater in irrigated agriculture-Review of some prac- tices in Spain and Greece 显示文摘 | Francisco P Ioannis K | 2010 | Agricultural Water Manage- ment2010，97，9： | 1 |
| 16 | Dermatomyositis as an early manifesta- tion and a significant clinical precursor of lung cancer:report of a rare case and review of the current literature显示文摘 | Nikolaos T Maria T Ioannis K D | 2013 | Int J Clin Exp Med2013，6，2： | 1 |
| 17 | Does ischemic preconditioning reduce spinal cord injury because of descending thoracic aortic occlusion显示文摘 | Ioannis K Constantine E | 2003 | J Vase Surg2003，37，2： | 1 |
| 18 | Systematic design of adaptive controllers for feedback linearizable system 显示文摘 | Ioannis K | 1991 | IEEE Trans on Automatic Control1991，36，11： | 1 |
| 19 | Exposure to major volatile organic compounds and carbonyls in European indoor environments and associated health risk 显示文摘 | DIMOSTHENIS A S SPYROS P K ALBERTO G IOANNIS L L ATHANASIOS K | 2011 | Environment International2011，37，4： | 1 |
| 20 | IL-10 producing regulatory B cells (B10 cells) in autoimmune disease 显示文摘 | Ioannis K Ayumi Y Thomas FT | 2013 | Arthritis R & T2013，15，1： | 1 |
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