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| 1 | Nanoparticle-Mediated Genetic Engineering of Plants显示文摘Genetic engineering of plants is at the core of sustainability efforts,natural product synthesis,and agricultural crop improvement.The past several decades have brought remarkable progress in biotechnology with the improvement of genome editing and sequencing tools,which stand to advance plant synthetic biology and bioengineering.In agriculture,genetic engineering can be employed to create crops that have in creased yields and nu tritio nal value,are resista nt to herbicides,in sects,diseases,and abiotic stresses,in cludi ng drought and heat .In pharmaceuticals and therapeutics,genetically engineered plants can be used to synthesize valuable small-molecule drugs and recombinant proteins. | Jeffrey W.Wang Eduardo G.Grand io Gregory M.Newkirk Gozde S.Demirer Salwan Butrus Juan Pablo Giraldo Markita P.Landry | 2019 | Molecular Plant2019，12，8： | 4 |
| 2 | 缺血期补充硝酸甘油对离体大鼠心脏心肌缺血再灌注损伤的作用显示文摘目的:观察离体大鼠心脏缺血期补充一氧化氮(NO)供体对缺血再灌注损伤的影响。 方法:将26只离体大鼠心脏缺血30分,再灌注60分。分为两组,用药组(15只)及对照组(11 只)。用药组于缺血期给予4.4×10- 3 mm ol/L硝酸甘油(nitroglycerin,NTG,一种NO供体),碳酸氢盐缓冲液灌注。对照组仅给予碳酸氢盐缓冲液灌注。全部心脏均测定NO释放量、肌酸激酶漏出量及(或)心脏功能。 结果:用药组大鼠心脏,使用NTG表现为两种效应。其中部分大鼠心脏(非心室颤动组,n= 7),NTG增加肌酸激酶漏出量,减弱再灌注期心脏功能的恢复,伴随缺血期NO释放量的增加。对另一部分大鼠心脏(心室颤动组,n= 8),NTG减少肌酸激酶的释放,但心脏于再灌注期持续心室颤动,缺血期NO释放量无明显增加。 结论:缺血期给予同一剂量NTG对心肌缺血再灌注损伤产生双重效应,既可增加心肌损伤,又可减轻心肌损伤。 | 刘海波 Takayuki T su ji Fum io Y am amoto Tosh ia Fujisato Hidekazu H irai Fu jio Miyaw aki | 1999 | 中国循环杂志1999，14，4： | 3 |
| 3 | Hematological profile of pregnant women in southwest of Nigeria显示文摘 | IO Osonuga OA Osonuga AA Onadeko A Osonuga AA Osonuga | 2011 | Asian Pacific Journal of Tropical Disease2011，，3： | 2 |
| 4 | Schistosoma mansoni in mice: the pattern of primary cercarial exposure determines whether a secondary infection post-chemotherapy elicits a T helper 1- or a T helper 2-associated immune response显示文摘 | Farah IO Johansson M Lovgren-Bengtson K | | Scand0，，： | 2 |
| 5 | Prevalence of hypoglycemia among severe malaria children in a rural African population显示文摘 | OA Osonuga AA Osonuga IO Osonuga A Osonuga Kwarteng L Derkyi | 2011 | Asian Pacific Journal of Tropical Disease2011，，3： | 2 |
| 6 | Temperature-and thickness-dependence of robust out-of-plane ferroelectricity in CVD grown ultrathin van der Waals a-In2Se3 layers显示文摘Two-dimensional(2D)ferroelectric materials with unique structure and extraordinary optoelectrical properties have attracted intensive research in the field of nanoelectronic and optoelectronic devices,such as optical sensors,transistors,photovoltaics and non-volatile memory devices.However,the transition temperature of the reported ferroelectrics in 2D limit is generally low or slightly above room temperature,hampering their applications in high-temperature electronic devices.Here,we report the robust high-temperature ferroelectricity in 2D a-In2Se3,grown by chemical vapor depostion(CVD),exhibiting an out-of-plane spontaneous polarization reaching above 200℃.The polarization switching and ferroelectric domains are observed in In2Se;nanoflakes in a wide temperature range.The coercive field of the CVD grown ferroelectric layers ilustrates a room-temperature thickness dependency and increases drastically when the film thickness decreases;whereas there is no large variance in the coercive field at dfterent termperature from the samples with identical thickness.The results show the stable ferroelectricit of In2Se3 nanoflakes maintained at high temperature and open up the opportunities of 2D materials for novel applications in high-temperature nanoelectronic devices. | Weng Fu Io Shuoguo Yuan Sin Yi Pang Lok Wing Wong Jiong Zhao Jianhua Hao | 2020 | Nano Research2020，13，7： | 2 |
| 7 | channel biology:p64 and the CLIC family of putative intracellular anion channel proteins (review) 显示文摘 | Ashley RH: Challenging accepted io | 2003 | Mol Membr Biol2003，20，： | 1 |
| 8 | Hepatectomy for hepatocellular carcinoma:The surgeon,s role in long-term survival显示文摘 | Fan ST Ng IO Poon RT | 1999 | Arch Surg1999，134，10： | 1 |
| 9 | Meningioangiomatosis:MR imaging and pathological correlation in two cases显示文摘 | Kim WY Kim IO Kim WS Cheon JE Yeon KM | 2002 | Pediatr Radiol2002，32，： | 1 |
| 10 | Serum vascular endothelial growth factor predicts venous invasion in hepatocellular carcinoma: a prospective study显示文摘 | Ng IO Lau C | 2001 | Ann Surg2001，233，2： | 1 |
| 11 | The effects of psychosocial services in substance abuse treatment 显示文摘 | McLellan AT Amdt IO Metzger DS | 1993 | JAMA1993，269，15： | 1 |
| 12 | Helicobacter pylori CagA phosphorylation status determines the gp130-activated SHP2/ERK and JAK/STAT signal transduction pathways in gastric epithelial cells显示文摘 | Lee IO Kim JH | 2010 | J Biol Chem2010，285，16： | 1 |
| 13 | Impact of basal-like breast carcinoma determination for a more specific therapy显示文摘 | Rakha EA Reis-Filho JS Ellis IO | 2008 | Pathobiology2008，75，2： | 1 |
| 14 | Cisplatin plus gemcitabine versus a cisplatin based triplet versus nonplatinum sequential doublets in advanced non-small cell lung cancer: a Spanish Lung Cancer Group phase Ⅲ randomized trial显示文摘 | ALBEROLA V CAMPS C PROVENC IO M | 2003 | J Clin Oncol2003，21，17： | 1 |
| 15 | Radiological features of focal nodular hyp erplasia of the liver in children显示文摘 | Cheon JE Kim WS Kim IO | 1998 | Pediatr Radiol1998，28，11： | 1 |
| 16 | Hospitalizations for bacterial pneumonia after renal transplantation in the United States显示文摘 | Tveit DJ Hypolite IO Poropatich RK | 2002 | Journal of Nephrology2002，15，3： | 1 |
| 17 | High-throughput tissue microarray analysis of c-myc activation in chronic liver diseases and hepatocellular carcinoma显示文摘 | Chan KL Guan XY Ng IO | 2004 | Hum Pathol2004，35，11： | 1 |
| 18 | Impact of a national external quality assessment scheme for breast pathology in the UK显示文摘 | Ellis IO Coleman D Wells C | 2006 | Clin Pathol2006，59，2： | 1 |
| 19 | Prediction of the response to citalopram and reboxetine in post - stroke de- pressed patients 显示文摘 | Rampello L Chiech io S Nicoletti G | 2004 | Psychopharmacology2004，173，12： | 1 |
| 20 | Breast tumor resembling the tall cell variant of papillary thyroid carcinoma: report of 5 cases 显示文摘 | Eusebi V Damiani S Ellis IO | 2003 | Am J Surg pathol2003，27，8： | 1 |
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