|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Biofilm three-dimensional architecture influences in situ pH distribution pattern on the human enamel surface显示文摘To investigate how the biofilm three-dimensional(3D) architecture influences in situ pH distribution patterns on the enamel surface. Biofilms were formed on human tooth enamel in the presence of 1% sucrose or 0.5% glucose plus 0.5% fructose. At specific time points, biofilms were exposed to a neutral pH buffer to mimic the buffering of saliva and subsequently pulsed with 1% glucose to induce re-acidification. Simultaneous 3D pH mapping and architecture of intact biofilms was performed using two-photon confocal microscopy. The enamel surface and mineral content characteristics were examined successively via optical profilometry and microradiography analyses. Sucrose-mediated biofilm formation created spatial heterogeneities manifested by complex networks of bacterial clusters(microcolonies). Acidic regions(pH<5.5) were found only in the interior of microcolonies,which impedes rapid neutralization(taking more than 120 min for neutralization). Glucose exposure rapidly re-created the acidic niches, indicating formation of diffusion barriers associated with microcolonies structure. Enamel demineralization(white spots),rougher surface, deeper lesion and more mineral loss appeared to be associated with the localization of these bacterial clusters at the biofilm-enamel interface. Similar 3D architecture was observed in plaque-biofilms formed in vivo in the presence of sucrose. The formation of complex 3D architectures creates spatially heterogeneous acidic microenvironments in close proximity of enamel surface, which might correlate with the localized pattern of the onset of carious lesions(white spot like) on teeth. | Jin Xiao Anderson T Hara Dongyeop Kim Domenick T Zero Hyun Koo Geelsu Hwang | 2017 | International Journal of Oral Science2017，9，2： | 4 |
| 2 | Cryptanalysis of enhancement for simple authentication key agreement algorithm显示文摘 | Hsieh B T Sun H M Hwang T | 2002 | Electronics Letters2002，38，1： | 2 |
| 3 | Multicenter evaluation of recurrence in endoscopic submucosal dissection and endoscopic mucosal resection in the colon:A Western perspective显示文摘BACKGROUND While colon endoscopic mucosal resection(EMR)is an effective technique,removal of larger polyps often requires piecemeal resection,which can increase recurrence rates.Endoscopic submucosal dissection(ESD)in the colon offers the ability for en bloc resection and is well-described in Asia,but there are limited studies comparing ESD vs EMR in the West.AIM To evaluate different techniques in endoscopic resection of large polyps in the colon and to identify factors for recurrence.METHODS The study is a retrospective comparison of ESD,EMR and knife-assisted endoscopic resection performed at Stanford University Medical Center and Veterans Affairs Palo Alto Health Care System between 2016 and 2020.Knife-assisted endoscopic resection was defined as use of electrosurgical knife to facilitate snare resection,such as for circumferential incision.Patients≥18 years of age undergoing colonoscopy with removal of polyp(s)≥20 mm were included.The primary outcome was recurrence on follow-up.RESULTS A total of 376 patients and 428 polyps were included.Mean polyp size was greatest in the ESD group(35.8 mm),followed by knife-assisted endoscopic resection(33.3 mm)and EMR(30.5 mm)(P<0.001).ESD achieved highest en bloc resection(90.4%)followed by knife-assisted endoscopic resection(31.1%)and EMR(20.2%)(P<0.001).A total of 287 polyps had follow-up(67.1%).On follow-up analysis,recurrence rate was lowest in knife-assisted endoscopic resection(0.0%)and ESD(1.3%)and highest in EMR(12.9%)(P=0.0017).En bloc polyp resection had significantly lower rate of recurrence(1.9%)compared to non-en bloc(12.0%,P=0.003).On multivariate analysis,ESD(in comparison to EMR)adjusted for polyp size was found to significantly reduce risk of recurrence[adjusted hazard ratio 0.06(95%CI:0.01-0.57,P=0.014)].CONCLUSION In our study,EMR had significantly higher recurrence compared to ESD and knife-assisted endoscopic resection.We found factors including resection by ESD,en bloc removal,and use of circumferential incision were associated with significantly decreased recurrence.While further studies are needed,we have demonstrated the efficacy of ESD in a Western population. | Mike T Wei Margaret J Zhou Andrew A Li Andrew Ofosu Joo Ha Hwang Shai Friedland | 2023 | World Journal of Gastrointestinal Endoscopy2023，15，6： | 2 |
| 4 | Electrical properties of the 85% Bi2 Te3 - 15% Bi2 Se3 thermoelectric material doped with SbI3 and CuBr显示文摘 | Hyun D B Hwang J S Oh T S | 1998 | J Phys Chem Solids1998，59，67： | 2 |
| 5 | Improvements in sintered density and dimensional stability of powder injection-molded 316L compacts by adjusting the alloying compositions显示文摘 | Shu G J Hwang K S Pan Y T | 2006 | Acta Materialia2006，54，2006： | 1 |
| 6 | Denaturation and change in SH group of antomyosin from milkfish during frozen storage at-20℃显示文摘 | Jang S T Hwang D C Chen C S | 1988 | Journal of Agriculture and Food Chemistry1988，36，： | 1 |
| 7 | Improved set estimators for a multivariate normal mean显示文摘 | Casella G | 1984 | Statistics & Decisions Supplement Issue1984，，1： | 1 |
| 8 | Grinding mechanism and energy balance for ceramics 显示文摘 | T W Hwang S Malkin | 1999 | Journal of Manufacturing Science and Engineering1999，121，4： | 1 |
| 9 | Factors predictive of liver cirrhosis in patients with chronic hepatitis B:a multivariate analysis in a longitudinal study显示文摘 | Huo T Wu JC Hwang SJ | 2000 | Eur J Gastroenterol Hepatol2000，12，6： | 1 |
| 10 | Comparison of ecotourism policies and implications for China's ecotourism development 显示文摘 | Wang S Heo J Yamada N Hwang S T | 2009 | Journal of China Tourism Research2009，5，3： | 1 |
| 11 | Water-soluble characteristics of chlorine in char derived from municipal solid wastes显示文摘 | Hwang I H Matsuto T Tanaka N | 2006 | Waste Management2006，26，6： | 1 |
| 12 | Design of integrated chassis control logics for AFS and ESP显示文摘 | Hwang T H Park K Heo S J | 2008 | International Journal of Automotive Technology2008，9，1： | 1 |
| 13 | Predictive and prognostic impact of epidermal growth factor receptor mutation in non-small-cell lung cancer patients treated with Gefitinib显示文摘 | HAN S W KIM T Y HWANG P G | 2005 | J Clin Oncol2005，23，11： | 1 |
| 14 | Blockade of the epidermal growth factor receptor tyrosine kinase activity by quercetin and luteolin leads to growth inhibition and apoptosis of pancreatic tumor cells 显示文摘 | Lee L T Huang YT Hwang J J | 2002 | Anticancer Res2002，22，3： | 1 |
| 15 | Vibrio alginolyticus, a tetrodotoxin-producing bacterium, in the intestines of the fish Fugu vermicularis vermicularis 显示文摘 | Noguchi T Hwang D F Arakawa O | 1987 | Marine Biology1987，94，： | 1 |
| 16 | Bias enhanced nucleation and bias textured growth of diamond on Si (100) in hot filament chemical vapor deposition显示文摘 | Huang J T Yeh W Y Hwang J | 1995 | Thin Solid Film1995，，315： | 1 |
| 17 | Stand-ardization of ^152Eu and ^88Y显示文摘 | PARK T S LEE J M HWANG H Y | 2002 | Applied Radiation and Isotopes2002，56，： | 1 |
| 18 | Induced growth ofBG-1 ovarian cancer cells by 17(3-estradiol or various endocrinedisrupting chemicals was reversed by resveratrol viadownregulation of cell cycle progression显示文摘 | Kang N H Hwang K A Kim T H | 2012 | Mol Med Report2012，6，1： | 1 |
| 19 | Three-axis machining of compound surfaces using flat and filleted end mills显示文摘 | HWANG J S CHANG T C | 1998 | CAD1998，30，8： | 1 |
| 20 | Synthesis of poly?aniline/Tit), hybrid nanoplates via a sol-gel chemical method显示文摘 | Katoch A Burkhart M Hwang T et a1 | 2012 | Chern Eng J2012，192，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员