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| 1 | Prognostic value of ^(18)F-FDG PET/CT in liver transplantation for hepatocarcinoma显示文摘AIM:To evaluate the prognostic value of pretreatment F D G p o s i t r o n e m i s s i o n t o m o g ra p h y c o m p u t e d tomography(PET-CT) in patients with hepatocarcinoma treated by liver transplantation(LT).METHODS:The authors retrospectively analyzed the data of 27 patients(mean age 58 ± 9 years) who underwent FDG PET-CT before LT for hepatocarcinoma.Mean follow-up was 26 ± 18 mo.The FDG PET/CT was performed according to a standard clinical protocol:4 MBq FDG/kg body weight,uptake 60 min,low-dose non-enhanced CT.The authors measured the SUVmax and SUVmean of the tumor and the normal liver.The tumor/liver activity ratios(RSUVmax and RSUVmean) were tested as prognostic factors and compared to the following conventional prognostic factors:MILAN,CLIP,OKUDA,TNM stage,alphafoetoprotein level,portal thrombosis,size of the largest nodule,tumor differentiation,microvascular invasion,underlying cirrhosis and liver function.RESULTS:Overall and recurrence free survivals were80.7%and 67.4%at 3 years,and 70.6%and 67.4%at 5 years,respectively.According to a multivariate Cox model,only FDG PET/CT RSUVmax predicted recurrence free survival.Even though the MILAN criteria alone were not predictive,it is worth noting that none of the patients outside the MILAN criteria and with RSUVmax<1.15 relapsed.CONCLUSION:FDG PET/CT with an RSUVmax cutoff value of 1.15 is a strong prognostic factor for recurrence and death in patients with HCC treated by LT in this retrospective series.Further prospectivestudies should test whether this metabolic index should be systematically included in the preoperative assessment. | Olivier Detry Laurence Govaerts Arnaud Deroover Morgan Vandermeulen Nicolas Meurisse Serge Malenga Noella Bletard Charles Mbendi Anne Lamproye Pierre Honoré Paul Meunier Jean Delwaide Roland Hustinx | 2015 | World Journal of Gastroenterology2015，21，10： | 5 |
| 2 | Usefulness of (18 ) F-FDG PET in the post-therapy surveillance of endometrial carcinoma 显示文摘 | Belhocine T De Barsy C Hustinx R | 2002 | Eur J Nucl Med Mol Imaging2002，29，9： | 1 |
| 3 | PET scan imaging in oncology显示文摘 | Jerusalem G Hustinx R Beguin Y | 2003 | Eur J Cancer2003，39，11： | 1 |
| 4 | 18F-FDG PET imaging of rheumatoid knee synovitis correlates with dynamic magnetic resonance and sonographic assessments as well as with the serum level of metalloproteinase-3显示文摘 | Catherine Beckers Xavier Jeukens Clio Ribbens Béatrice André Stefaan Marcelis Philippe Leclercq Marie-Jo?lle Kaiser Jacqueline Foidart Roland Hustinx Michel G. Malaise | 2006 | European Journal of Nuclear Medicine and Molecular Imaging2006，，3： | 1 |
| 5 | Positron emission tomography(PET) for staging low-grade non-Hodgkin's lymphomas (NHL) 显示文摘 | Najjar F Hustinx R Jerusalem G | 2001 | Cancer Biother Radiopharm2001，16，4： | 1 |
| 6 | Dual time point fluorine-18 fluorodeo-xyglucose positron emission tomography:a potential method to differentiate malignancy from inflammation and normal tissue in the head and neck显示文摘 | HUSTINX R SMITH R J BENARD F | 1999 | Eur J Nucl Med1999，26，： | 1 |
| 7 | Differentially expressed genes in pancreatic ductal adenocarcinomas identified through serial analysis of gene expression显示文摘 | Hustinx SR Cao D Maitra A | 2004 | Cancer Biol Ther2004，3，12： | 1 |
| 8 | Expression and prognostic significance of 14-3-3sigma and ERM family protein expression in periampullary neoplasms显示文摘 | Hustinx SR Fukushima N Zahurak ML | 2005 | Cancer Biol Ther2005，4，： | 1 |
| 9 | Novel alleles at the Jk blood group locus explain the absence of the erythrocyte urea transporter in European families显示文摘 | Irshaid NM Eicher NI Hustinx H | 2002 | Br J Haematol2002，116，2： | 1 |
| 10 | Pancreatic carcinogenesis显示文摘 | Koorstra JB Hustinx SR Offerhaus GJ | 2008 | Pancreatology2008，8，2： | 1 |
| 11 | Imaging gliomas with positron emission tomography and single-photon emission computed tomography显示文摘 | Benard F Romsa J Hustinx R | 2003 | Semin Nucl Med2003，33，2： | 1 |
| 12 | Measuring the effect of amantadine in chronic anoxic vegetative state显示文摘 | Schnakers C Hustinx R Vandewalle G | 2008 | J Neurol Neurosurg Psychiatry2008，79，2： | 1 |
| 13 | 早期将抗生素由静脉转为口服治疗严重社区获得性肺炎:多中心随机试验显示文摘目的比较早期由静脉转换成口服抗生素与常规静脉使用7天抗生素治疗严重社区获得性肺炎(CAP)的疗效。设计多中心随机对照试验。地点荷兰5家教学医院和2所大学的医学中心。参加者非 ICU 住院的严重 CAP 患者302例,其中265例满足研究要求。干预静脉抗生素治疗3天,病情稳定后换成口服抗生素,或静脉使用抗生素治疗7天。主要评价结果临床治愈和住院天数。结果 302例患者被随机分组(平均年龄69.5岁,标准差14.0),肺炎严重度评分平均112.7(26.0)。37例患者因为提前3天退出而未纳入分析,对其余265例患者进行分析研究。第28天的死亡率在干预组是4%,对照组是6%(平均差2%,95%可信区间-3%~8%)。临床治愈率在干预组是83%,对照组是85%(2%;-7%~10%)。与对照组相比,干预组患者静脉治疗时间为3.4天[3.6(1.5)比7.0(2.0)天;2.8~3.9],患者住院天数减少1.9天[9.6(5.0)比11.5(4.9)天;0.6~3.2]。结论早期将抗生素由静脉应用转换成口服治疗严重 CAP 是安全的,并且可以减少住院时间2天。试验注册号临床试验 NCT00273676。 | Jan Jelrik Oosterheert Marc J M Bonten Margriet M E Schneider Erik Buskens Jan-Willem J Lammers Willem M N Hustinx Mark H H Kramer Jan M Prins Peter H Th J Slee Karin Kaasjager Andy I M Hoepelman 王伟巍(译) 童朝辉(校) | 2007 | 英国医学杂志中文版2007，10，2： | 1 |
| 14 | Heat-Induced Hydrolysis of Sodium Caseinate 显示文摘 | HUSTINX J C A SINGH T K FOX P F | 1997 | International Dairy Journal1997，7，4： | 1 |
| 15 | PET scan imaging in oncology显示文摘 | JERUSALEM G HUSTINX R BEGUIN Y | 2003 | Eur J Cancer2003，39，11： | 1 |
| 16 | 18-Fluoro-deoxyglucose uptake in inflammatory hepatic adenoma:A case report显示文摘Positron emission tomography computed tomography(PET-CT) using ^(18)-Fluoro-deoxyglucose(^(18)FDG) is an imaging modality that reflects cellular glucose metabolism. Most cancers show an uptake of ^(18)FDG and benign tumors do not usually behave in such a way. The authors report herein the case of a 38-year-old female patient with a past medical history of cervical intraepithelial neoplasia and pheochromocytoma, in whom a liver lesion had been detected with PET-CT. The tumor was laparoscopically resected and the diagnosis of inflammatory hepatic adenoma was confirmed. This is the first description of an inflammatory hepatic adenoma with an ^(18)FDG up-take. | Willy Liu Jean Delwaide Noella Bletard Philippe Delvenne Paul Meunier Roland Hustinx Olivier Detry | 2017 | World Journal of Hepatology2017，9，11： | 1 |
| 17 | Dual time point fluorine-18 fluorodeoxyglucose positron emission tomography: a potential method to differentiate malignancy from inflammation and normal tissue in the head and neck 显示文摘 | Hustinx R Smith RJ Benard F | 1999 | Eur J Nucl Med1999，26，10： | 1 |
| 18 | Evaluation of therapy for lymphoma 显示文摘 | Jerusalem G Hustinx R Beguin Y | 2005 | Semin Nucl Med2005，35，3： | 1 |
| 19 | Evaluation of therapy for lymphoma显示文摘 | Jerusalem G Hustinx R Beguin Y | 2005 | Semin Nuel Med2005，35，3： | 1 |
| 20 | Whole-body positron emission tomography using Fluorodeoxyglucose in patients with metastases of unknown primary tumours (CPU syndrome) 显示文摘 | Belhocine T Hustinx R | 2003 | Nucl Med Commun2003，24，10： | 1 |
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