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39篇 您的检索式:作者名="Hudmon"
    题名 作者 年代 出处 被引量
1CaMKII in cerebral ischemia显示文摘神经原上的 Ischemic 侮辱触发引起 Ca 导致 neuronal 房间死亡(excitotoxicity ) 的 2+ 超载的过多的、病理学的 glutamate 版本。Ca 2+/calmodulin (凸轮) 依赖者蛋白质 kinase II (CaMKII ) 是位于 neuronal 粘性下面并且学习的生理的有刺激性的 glutamate 信号的一个主要调停人。Glutamate 刺激在 T286 触发 CaMKII 的 autophosphorylation,使 kinase 成为 “ 的一个过程; autonomous”(从 Ca 2+ 刺激的部分活跃的独立人士) 并且那为 synaptic 的形式被要求粘性。最近的研究为侮辱以后的 neuroprotection 作为潜在的药目标也建议了自治 CaMKII 活动,在在 neuronal 文化的 glutamate 侮辱以后并且在在 vivo 的焦点的服的局部缺血以后。然而, CaMKII 和凸轮 kinase 家庭的另外的成员在 neuronal 死亡和幸存的规定被含有。这里,我们在 excitotoxicity 和服的局部缺血讨论过去的调查结果和凸轮 kinase 功能的可能的机制,与 CaMKII 和它的规定的一个焦点。Steven J COULTRAP Rebekah S VEST Nicole M ASHPOLE Andy HUDMON K Ulrich BAYEF 2011Acta Pharmacologica Sinica2011,32,7:6
2Molecular basis of calmodulin tethering and Ca2+-dependent inactivation of L-type Ca2+ channels显示文摘Pitt GS Zuhlke RD Hudmon A 2001J Biol Chem2001,276,30:1
3The pharmacist's role in smoking cessation counseling:perceptions of users of nonprescription nicotine replacement therapy显示文摘HUDMON K S HEMBERGER K K CORELLI R L 2003J Am Pharm Assoc2003,43,5:1
4Structure-function of the multifunc- tional Ca2 +/calmodulin显示文摘Hudmon A Schulman H 2002Biochem J2002,364,3:1
5A mechanism for Ca2+/calmodulin-dependent proteinkinaseⅡclustering at synaptic and nonsynaptic sites based onself-association显示文摘Hudmon A Lebel E Roy H Sik A Schulman H Waxham MN 2005J Neurosci2005,25,:1
6A train the-trai- ner approach to a shared pharmacogenomics curriculum for US colleges and schools of pharmacy显示文摘Lee K C Ma J D Hudmon K S 2012Am J Pharm Educ2012,76,10:1
7Current approaches to pharmacotherapy for smoking cessation显示文摘Hudmon KS Corelli RL Prokhorov AV 2010Ther Adv Respir Dis2010,4,1:1
8Tobacco con- trol in state comprehensive cancer control plans: op- portunities for decreasing tobacco-related disease 显示文摘Kilfoy B A Hudmon K S Mande J R 2007Prey Chronic Dis2007,4,3:1
9Neuronal Ca^2 + /calmodulin-dependent protein kinase II: the role of structure and autoregulation in cellular function显示文摘Hudmon A Schulman H 2002Annu RevBiochem2002,71,:1
10Molecular basis of calmodulin tethering and Ca2+-dependent inactivation of L-type Ca2+channels显示文摘Pitt GS Zuhlke RD Hudmon A 2001J Biol Chem2001,276,30:1
11Ca MKⅡtethers to L-type Ca2+channels,establishing a local and dedicated integrator of Ca2+signals for facilitation显示文摘Hudmon A Schulman H Kim J 2005J cell boil2005,171,:1
12Structure-function of the muhifunetional Ca^2+/calmodulin-dependent protein kinase Ⅱ 显示文摘Hudmon A Sehulman H 2002Biochem J2002,364,3:1
13Molecular character- ization of calmodulin trapping by calcium/calmodulin-dependent protein kinaseⅡ 显示文摘Singla S I Hudmon A Goldberg J M 2001J Biol Chem2001,276,29:1
14Structure-function of the multifunctional Ca^2+/calmodulin-dependent protein kinaseⅡ显示文摘Hudmon A Schulman H 2002Biochem J2002,364,3:1
15Mitochondrial Ca2~ uniporter and CaMKII in heart 显示文摘Fieni F Johnson DE Hudmon A 2014Nature2014,513,7519:1
16Structure-function of the multifunctional Ca2 +/calmodulin-dependent protein kinase Ⅱ显示文摘Hudmon A Schulman H 2002Biochem J2002,364,3:1
17Structure - function of the muhifunctional Ca^2+/calmodulin-dependent protein kinase Ⅱ 显示文摘Hudmon A Schulman H 2002Biochem J2002,364,3:1
18Structure-function of the multifunctional Ca2+/calmodulin-dependent protein kinase Ⅱ显示文摘Hudmon A Schulman H 2002Biochem J2002,364,:1
19Structure-function of the multifunctional Ca2+/calmodulin-dependent protein kinase Ⅱ 显示文摘Hudmon A Schulman H 2002Biochem J2002,364,3:1
20Medications for smoking cessation显示文摘Corelli RL Hudmon KS 2002West J Med2002,176,2:1
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