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174篇 您的检索式:作者名="Horsten"
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1Extracellular quality control in the epididymis显示文摘因为发生在它的范围以内的活跃精子成熟过程,附睾腔代表唯一的细胞外的环境。尽管大部分集中在腔放在和精子的附睾的能分泌的蛋白质的相互作用上的过时的人或物,很,很少关于整个的复杂附睾周围怎么被维持被知道,包括阻止或控制不能呆在他们合拢的土著人的蛋白质州的列在后面的机制分泌物。因为一些错误褶层蛋白质能形成作为淀粉知道的细胞毒素的总数结构,控制 / 监视机制在附睾以内存在免于这进程并且允许精子成熟发生,是可能的。学习蛋白质聚集并且在附睾识别细胞外的质量控制机制,因为两蛋白质有固有的性质聚集并且形成 amyloid,我们把半胱氨酸朊酶禁止者,包括的 cystatin 相关的附睾精子发生的和 cystatin C 的 cystatin 家庭用作分子的模型。在这章,我们在场由淀粉的小径的蛋白质聚集的一篇简短摘要基于从另外的机关系统被知道并且描述细胞内部地存在到的质量控制机制的控制蛋白质错误褶层和聚集。我们然后介绍我们的研究的一篇摘要在附睾腔以内的 ofcystatin 相关的附睾精子发生的(CRES ) oligomerization,包括建议那 transglutaminase cross-linking 的研究可以是在附睾以内的细胞外的质量控制的一机制。Gail A. Cornwall H. Henning von Horsten Douglas Swartz Seethal Johnson Kim Chau Sandra Whelly 2007Asian Journal of Andrology2007,9,4:3
2Novel antimicrobial peptide of human epididymal duct origin 显示文摘von Horsten HH Derr P Kirchhoff C 2002Biol Reprod2002,67,3:1
3Human epididy- mis protein 4 ( HE4 ) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carci- nomas 显示文摘Drapkin R von Horsten HH Lin Y 2005Cancer Res2005,65,6:1
4Human epididymis protein 4(HE4) is a secreted glycoprotein that is overexpressed by serous andendometrioil ovarian carcinomas 显示文摘Drapkin R Von Horsten HH Lin Y 2005Cancer Res2005,65,6:1
5Human epidid- ymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carci- nomas显示文摘Drapkin R von Horsten H H Lin Y 2005Cancer Res2005,65,6:1
6Human epididymis pro- tein 4 (HE 4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carei-nomas显示文摘Drapkin R Von Horsten H H Lin Y 2005Cancer Res2005,65,6:1
7Five years' results from a long-term field experiment on carbendazim resistance of Pseudocercosporella herpotrichoides ( Fron ) Deighton 显示文摘FEHRMANN H HORSTEN J SIEBRASSE G 1982Crop Protection1982,1,2:1
8Human epididymis protein 4 (HFA) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas 显示文摘Drapkin R yon Horsten H H Lin Y 2005Cancer Res2005,65,6:1
9Human epididy- mis protein4 (HE4) is asecreted glycoproterin that is overexpressed by serous and endometrioid ovarian carcino- mas显示文摘Drapkin R Von Horsten H Lin Y 2005Cancer Res2005,65,6:1
10Depressive symptoms and lack of social integration in relation to prognosis of CHD in middle - aged women显示文摘Horsten M Mittleman MA Wamala SP 2000Eur Heart J2000,21,13:1
11Curcacycline A-a novel cyclic octapeptide isolated from the latex of dcaropha curcas Linn显示文摘Van A Horsten S Kettenes J 1995FEBS Letters1995,358,3:1
12Human epididymis protein 4(HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas显示文摘Drapkin R Horsten HH Lin Y 2005Cancer Res2005,65,:1
13Marital stess worsens prognosis in women with coronary heart disease:the stockholm female coronary risk stady显示文摘Orth-Gomer K Wamala SP Horsten M 2000JAMA2000,284,23:1
14Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas 显示文摘Drapkin R von Horsten HH Lin Y 2005Cancer Res2005,65,6:1
15Human epididymis protein 4(HFA)is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas显示文摘Drapkin R von Horsten HH Lin Y 2005Cancer Res2005,65,6:1
16Human epididymis protein 4 (HE4)is a secreted glycoprotein that is overex- pressed by serous and endometrioid ovarian carcinomas显示文摘Drapkin R van Horsten HH Lin Y 2005Cancer Res2005,65,6:1
17Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas显示文摘Drapkin R Von Horsten HH Lin YF 2005Cancer Res2005,65,6:1
18Human eipididy misprotein 4(HE4)is a secreted glycoprotein that is ove-expressed by serous and endometrioid ovarian carcinomas 显示文摘Drapkin R Horsten HH Lin Y 2005Cancer Res2005,65,6:1
19Automated Behavioral Phenotyping Reveals Presymptomatic Alterations in a SCA3 Genetrap Mouse Model显示文摘neurodegenerative 混乱的疾病模型的描述以一种高度标准化的方式要求系统、全面的 phenotyping。因此,自动化了象基于的 LabMaster 系统具有特别兴趣的 homecage 那样的高分辨率的行为测试系统。我们由发现一个最近描绘的 atxn3 异种老鼠模型的以前未被认出的特征表明自动化 LabMaster 系统的力量。这个模型在 12 个月岁时包括步法混乱,震颤,重量损失和早熟的死亡提供了神经病学的症状通常可检测就在老鼠前的 2 个星期死了。而且,用 LabMaster 系统,我们能在黑暗以及轻的阶段在 presymptomatic 异种老鼠检测 hypoactivity。另外,我们分析了发炎,免疫学的和 hematological 参数,它在 phenotypic 鼠标显示了减少的有免疫力的防卫。这里,我们证明甚至通常没在 SCA3 被影响的机关系统的详细描述为致病的进一步的研究是重要的并且为现出症状之前的潜的治疗学的研究要求。Jeannette Hübener Nicolas Casadei Peter Teismann Mathias W. Seeliger Maria Bjrkqvist Stephan von Horsten Olaf Riess Huu Phuc Nguyen 2012Journal of Genetics and Genomics2012,39,6:1
20Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas 显示文摘Drapkin R Horsten HH LinY 2005Cancer Res2005,65,:1
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