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| 1 | Chinese Atherosclerosis Risk Evaluation(CARE II)study:a novel cross-sectional,multicentre study of the prevalence of high-risk atherosclerotic carotid plaque in Chinese patients with ischaemic cerebrovascular events-design and rationale显示文摘Background:Carotid atherosclerotic plaque is identified as one of the main sources of ischaemic stroke.However,the prevalence of carotid high-risk atherosclerotic plaque in Chinese patients with ischaemic cerebrovascular events has been inconsistently reported and needs to be investigated in a large population.Objectives:The primary objective of CARE II study was to determine the prevalence and characteristics of high-risk features of atherosclerotic plaques in the carotid arteries in Chinese patients with recent ischaemic stroke or transient ischaemia attack(TIA).The relationship between carotid plaque features and cerebral infarcts,the differences of carotid plaque patterns among different regions of China and the gender specific characteristics of carotid plaque will be also determined.Study design:The CARE II study will enrol 1000 patients with recent ischaemic stroke or TIA and carotid plaque from 13 hospitals and medical centres across China.In this cross-sectional,non-randomised,observational,multicentre study,all patients will undergo carotid artery MRI of bilateral carotid arteries and routine brain MRI with standardised protocols.The MRI will be interpreted at core reading centres to evaluate the characteristics of morphology and compositions of carotid plaque.Conclusions:This is a cross-sectional,multicentre study to investigate the prevalence and characteristics of high-risk atherosclerotic carotid plaque in Chinese patients with stroke and TIA by using high-resolution MRI of vessel wall.This trial is sufficiently powered to demonstrate the prevalence of carotid high-risk plaque and to explore regional differences in Chinese patients who suffered stroke. | Xihai Zhao Rui Li Daniel S Hippe Thomas S Hatsukami Chun Yuan CARE-II Investigators | 2017 | Stroke & Vascular Neurology2017，2，1： | 21 |
| 2 | The spatial structure of phylogenetic and functional diversity in the United States and Canada: An example using the sedge family (Cyperaceae)显示文摘越过风景的系统地确定的差异是必要的理解 clade 历史和生态的异质怎么贡献生物多样性的起源,分发,和维护。这里,我们在整个 USA 和加拿大在薹家庭(Cyperaceae ) 在所有种类之中制定差异的空间结构。我们首先识别显著种类丰富,种系发生的差异,和功能的特点差异的区域,并且加亮保存优先级的区域。我们然后基于家庭的历史的生物地理学关于这差异的空间结构测试预言。合并发展史,在从联机植物群的功能的特点 mined 的 400000 个腊叶集记录,和一个数据库上,我们发现那种丰富和功能的特点差异在东北美国的山峰,当时沿着墨西哥湾的种系发生的差异山峰。在集合之中的花的周转与距离显著地增加,但是种系发生的周转是两次象纵的坡度同样沿着纬度的坡度快速。这些模式反映 Cyperaceae 的期望的分发,它在热带发源,但是在适度的区域放射了。我们与许多识别集合稀罕, rangerestricted 系,和集合通常从多样的区域缺乏的种类创作了。我们主张这两个度量标准为开发指向的保存策略是有用的。我们使用这里产生建立未来研究优先级的数据,包括测试关于在薹划分的染色体数字,光合的小径,和资源的分发的一系列假设。 | Daniel Spalink Jocelyn Pender Marcial Escudero Andrew L. Hipp Eric H. Roalson Julian R. Starr Marcia J. Waterway Lynn Bohs Kenneth J. Sytsma | 2018 | Journal of Systematics and Evolution2018，56，5： | 10 |
| 3 | Differences in atheroma between Caucasian and Asian subjects with anterior stroke:A vessel wall MRI study显示文摘Background and purpose While extracranial carotid artery stenosis is more common among Caucasians and intracranial artery stenosis is more common among Asians,the differences in atherosclerotic plaque characteristics have not yet been extensively examined.We sought to investigate plaque location and characteristics within extracranial carotid and intracranial arteries in symptomatic Caucasians and Chinese using vessel wall MRI.Methods Subjects with recent anterior circulation ischaemic stroke were recruited and imaged at two sites in the USA and China using similar protocols.Both extracranial carotid and intracranial arteries were reviewed to determine plaque location and characteristics.Results The prevalence of extracranial carotid plaque in Caucasians and Chinese was 73.1%and 49.1%,respectively(p=0.055).Prevalence of intracranial plaque was 38.5%and 69.1%in Caucasians and Chinese,respectively(p=0.02).Furthermore,42% of Caucasians and 16%of Chinese had high-risk plaque(HRP)features(intraplaque haemorrhage,luminal surface disruption)in the extracranial carotid artery(p=0.03).The prevalence of HRP features in intracranial arteries was not significantly different between the two cohorts(4%vs 11%;p=0.42).Conclusions Differences in the location and characteristics of cerebrovascular atherosclerosis were identified by vessel wall MRI in US Caucasian and Chinese subjects with recent anterior circulation ischaemic stroke.Extracranial carotid plaques with HRP features were more common in Caucasians.Intracranial plaques were more common in Chinese subjects,but no significant difference between the two cohorts in intracranial HRP prevalence was found.Larger studies using vessel wall imaging to investigate racial differences in cerebrovascular disease may inform underlying mechanisms of HRP development and may ultimately help guide appropriate therapy. | Hiroko Watase Mi Shen Binbin Sui Peiyi Gao Dong Zhang Jie Sun Niranjan Balu Daniel S Hippe Gail P Jarvik Xihai Zhao Rui Li Shuo Chen Chun Yuan Thomas S Hatsukami | 2021 | Stroke & Vascular Neurology2021，6，1： | 4 |
| 4 | Cytotoxic T cell immunity against telomerase reverse transcriptase in humans显示文摘 | MINEV B HIPP J FIRAT H | | 0，，： | 2 |
| 5 | Tissue engineering,stem cells,cloning, and parthenogenesis:new paradigms for therapy 显示文摘 | Hipp J Atala A | 2004 | J Exp Clin Assist Reprod2004，1，1： | 1 |
| 6 | Dynamicmeasuring of frequency and frequency oscillations in multiphase power systems显示文摘 | Eckhardt V Hippe P Hosemann G | 1989 | IEEE Trans PD1989，4，4： | 1 |
| 7 | Coracoclavicular ligament reconstruction using the lateral half of the conjoined tendon 显示文摘 | Sloan SM Budoff JE Hipp JA | 2004 | J Shoulder Elbow Surg2004，13，2： | 1 |
| 8 | Cytotoxic T-cell immunity against telomerase reverse transcriptase in humans 显示文摘 | Minev B Hipp J Firat H | 2000 | Proc Natl Acad Sci USA2000，97，9： | 1 |
| 9 | Asymptotics of ruin probabilities for controlled risk processes in the small claims case 显示文摘 | Hipp C Schmidli H | 2004 | Stand Actuarial J2004，，5： | 1 |
| 10 | Digital Tomosynthesis to Evaluate Fracture Healing: Prospective Comparison With Radiography and CT 显示文摘 | Ha AS Lee AY Hippe DS | 2015 | AJR Am J Roentgenol2015，205，1： | 1 |
| 11 | New clinical aspects of whole body hyperthermia显示文摘 | Eisler K Hipp R Gogler S | 1990 | Adv Exp Med Biol1990，267，： | 1 |
| 12 | Comparison of predicted and measured contact pressures in normal and dysplastic hips显示文摘 | Michaeli DA Murphy SB Hipp JA | 1997 | Med Eng phys1997，19，2： | 1 |
| 13 | Vesiculo-vacuolar organelles and the regulation of venule permeability to macromolecules by vascular permeability factor,histamine,and serotonin显示文摘 | Feng D Nagy AJ Hipp J | 1996 | J Exp Med1996，183，： | 1 |
| 14 | Algorithms for association rule mining:A general survey and comparison显示文摘 | Hipp J | 2000 | ACM SIGKDD Explorations2000，2，1： | 1 |
| 15 | A lower solubility recommends the use of desflurane more than isoflurane,halothane and enflurane under low flow condition显示文摘 | Hargasser S Hipp R Breinbener B | 1995 | J Clin Anesth1995，7，： | 1 |
| 16 | Proton magnetic resonance spectroscopy predicts survival in children with diffuse intrinsic pontine glioma 显示文摘 | Steffen-Smith EA Shih JH Hipp S J et O1 | 2011 | J Neurooncol2011，105，2： | 1 |
| 17 | Sustained Acceleration in arotid Atherosclerotic Plaque Progression With Intraplaque Hemorrhage显示文摘 | Sun J Underhill HR Hippe DS | 2012 | JACC Cardiovasc Imaging2012，5，8： | 1 |
| 18 | On the time to ruin for Erlang(2)risk process显示文摘 | Dickson D C M Hipp C | | 0，，： | 1 |
| 19 | C1 lateral mass screw placement via the posterior arch:a technique comparison and anatomic analysis显示文摘 | Lin JM Hipp JA Reitman CA | 2013 | Spine J2013，13，11： | 1 |
| 20 | Use of percutaneous transpedicular external fixation pins to measure intervertebral motion显示文摘 | Sahni IK Hipp JA Kirking BC | 1999 | Spine (Phila Pa 1976)1999，24，18： | 1 |
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