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| 1 | Sperm retrieval success and testicular histopathology in idiopathic nonobstructive azoospermia显示文摘Prior studies have investigated sperm retrieval rates in men with non obstructive azoospermia(NOA)secondary to specific etiologies,yet most cases of NOA are idiopathic.We compared sperm retrieval rates and testicular histopathology in idiopathic NOA(iNOA)and nonidiopathic NOA(niNOA).We performed a retrospective review of men with NOA who underwent microdissection testicular sperm extraction(microTESE)between 2000 and 2016.Men with no history of malignancy or cryptorchidism and negative genetic evaluation were considered idiopathic.Multivariable regression determined the association between idiopathic etiology and primary outcomes of sperm retrieval and active spermatogenesis on histopathology.Among 224 men,86(38.4%)were idiopathic,75(33.5%)were nonidiopathic,and 63(28.1%)did not undergo genetic testing.Median age and serum testosterone were higher among iNOA or no testing versus niNOA.Median follicle-stimulating hormone(FSH)was lower among iNOA or no testing versus niNOA.A higher proportion of iNOA or no testing versus niNOA had a clinical varicocele.Sperm retrieval rates were similar between iNOA,niNOA,and no testing(41.8%vs 48.0%vs 55.6%,respectively;P=0.255).Active spermatogenesis was seen in a higher proportion of iNOA or no testing versus niNOA(31.4%and 27.0%vs 16.0%,P=0.073).On multivariable analysis,iNOA was not associated with sperm retrieval or spermatogenesis(P=0.430 and P=0.078,respectively).Rates of sperm retrieval and spermatogenesis on testis pathology were similar in men with iNOA and niNOA.These data will be useful to clinicians in preoperative counseling for men with NOA and negative genetic evaluation. | Arighno Das Joshua A Halpern Annie L Darves-Bornoz Mehul Patel James Wren Mary Kate Keeter Robert E Brannigan | 2020 | Asian Journal of Andrology2020，22，6： | 3 |
| 2 | Liver X receptor (LXR)-beta regulation in LXR alpha-deficient mice: implications for therapeutic targeting显示文摘 | Quinet E M Savio D A Halpern A R | 2006 | Mol Pharmacol2006，70，4： | 1 |
| 3 | Lactobacillus GG bacteria ame- liorate arthritis in Lewis rats显示文摘 | Baharav E Mor F Halpern M | 2004 | The Journal of nutrition2004，134，8： | 1 |
| 4 | Accuracy of MDCT in as- sessing the degree of stenosis caused by calcified coronary artery plaques显示文摘 | Zhang S Levin D C Halpern E J | 2008 | AJR2008，191，6： | 1 |
| 5 | Contrast enhanced transrectal ultrasound for the detection of prostate cancer: a ran- domized, double-blind trial of dutasteride pretreatment 显示文摘 | Halpern E J Gomella LG Forberg F | 2012 | J Urol2012，188，： | 1 |
| 6 | Inflammatory low back pain: high negative predictive value of contrastenhanced color Doppler ultrasound in the detection of inflamed sacroiliac joints显示文摘 | Klauser A Halpern E J Frauscher F | 2005 | Arthritis Care and Research2005，53，3： | 1 |
| 7 | 'Sometimes' and 'not never' revisited:on branching versus linear time temporal logic显示文摘 | E A Emerson J Y Halpern | 1986 | Journal of the ACM1986，33，1： | 1 |
| 8 | Initial experience with contrast-enhanced sonography of the prostate显示文摘 | Halpern E J Verkh L Forsberg F | 2000 | AJR Am J Roentgenol2000，174，： | 1 |
| 9 | Inferior vena caval filters: review of a 26- year single center clinical experience 显示文摘 | ATHANASOULIS C A KAUFMAN J A HALPERN E F | 2000 | Radiology2000，216，1： | 1 |
| 10 | Potential response of pacific northwestern forests to climate change :effects of stand age and initial composition 显示文摘 | Urban D L Harmon M E Halpern C B | 1993 | Climatic Change1993，23，： | 1 |
| 11 | The dog genome:survey sequencing and comparative analysis显示文摘 | Kirkness E F Bafna V Halpern A L | 2003 | Science2003，301，5641： | 1 |
| 12 | Inferior vena eava filters : review of a 26-year single-center clinical experience显示文摘 | ATHANASOULIS C A KAUFMAN J A HALPERN E F | 2000 | Radiology2000，216，1： | 1 |
| 13 | Using gray-scale and color and power Doppler sonography to detect prostate cancer 显示文摘 | Halpern E J Strup SE | 2000 | A JR Am J Roentgenol2000，174，： | 1 |
| 14 | Contrast-enhanced ultrasound imaging of prostate cancer显示文摘 | Halpern E J | 2006 | Rev Urol2006，81，： | 1 |
| 15 | Normal renal artery spectral Doppler waveform: a closer look显示文摘 | Halpern E J Deane CR Needleman L | 1995 | Radiology1995，196，3： | 1 |
| 16 | A simple route to sterically pure diketopiperazines显示文摘 | Nitecki D E Halpern B Huffman J C | 1968 | J Org Chem1968，33，2： | 1 |
| 17 | Sarcoma-like mural nodules with foci of anaplastic carcinomas tumor:Clinical histological and immunohistochemical study of a case review of the literature显示文摘 | Kessler E Halpern M Koren R | 1990 | Surg Pathol1990，32，： | 1 |
| 18 | Quantitave,high resolustion measurement of cerebralvascular physiology with slip-ring CT显示文摘 | Hamberg L M Hunter G J Halpern E F | 1996 | AJNR1996，17，4： | 1 |
| 19 | Imaging of fallopian tube tumors显示文摘 | Slanetz P J Whitman G J Halpern E F | 1997 | AJR1997，169，5： | 1 |
| 20 | Hyperglycemia is associated with intracranial injury in children younger than 3 years of age显示文摘 | Babbitt CJ Halpern R Liao E | | 0，，03： | 1 |
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