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| 1 | Interaction of hepatitis C virus envelope glycoprotein E2 with the large extracellular loop of tupaia CD81显示文摘AIM: To further analyze the interaction of tupaia CD81 with hepatitis C virus (HCV) envelope protein E2. METHODS: A tupaia CD81 large extracellular loop (CD81 LEL), which binds to HCV E2 protein, was cloned and expressed as a GST-fusion protein, and interaction of HCV E2 protein with a tupaia CD81 LEL was evaluated by enzyme-linked immunosorbent assay (EIA). RESULTS: Although tupaia and human CD81 LEL differed in 6 amino acid changes, tupaia CD81 LEL was strongly recognized by anti-CD81 antibodies against human CD81 LEL conformation-dependent epitopes. Investigating LEL CD81-E2 interactions by EIA, we demonstrated that binding of tupaia CD81 LEL GST fusion protein to recombinant HCV E2 protein was markedly reduced compared to binding of human CD81 LEL GST fusion protein to recombinant HCV E2 protein. CONCLUSION: These data suggest that the structural differences in-between the tupaia and human CD81 may alter the interaction of the large extracellular loop with HCV envelope glycoprotein E2. These findings may be important for the understanding of the mechanisms of binding and entry of HCV to PTHs. | Zhan-Fei Tian Hong Shen Xi-Hua Fu Yi-Chun Chen Hubert E Blum Thomas F Baumert Xi-Ping Zhao | 2009 | World Journal of Gastroenterology2009，15，2： | 16 |
| 2 | The Erythropoietin Receptor: Dimerization and Intracellular Signal Transduction显示文摘Erythropoietin (EPO), a 34 kD glycopro-tein, is the principal growth factor regulating theproduction of circulating erythrocytes; EPO isessential for committed CFU - E erythroid pro-genitors to divide several times and then to dif-ferentiate into erythrocytes. Like most receptorsfor hematopoietic growth factors, the erythro-poietin receptor (EPO - R) is a type I trans-membrane protein and a member of the cytokinereceptor superfamily. These receptors containfour conserved cysteines and a Trp - Ser - X - | WU Hong Harvey F Lodish(Whitehead Institute for Biomedical Research, Nine Cambridge Center Cambridge MA 02142 USA) (Department of Biology, Massachusetts Institute of Technology Cambridge MA 02139 USA) | 1996 | 中国实验血液学杂志1996，4，3： | 4 |
| 3 | Notes on power LCM matrices显示文摘 | Hong S F | 2004 | Acta Arithmetica2004，111，： | 2 |
| 4 | On the factorization of LCM matrices on gcd-closed sets显示文摘 | Hong S F | 2002 | Linear Algebra Appl2002，345，： | 2 |
| 5 | Development of the High Concentration Ⅲ-Ⅴ Photovoltaic System at INER, Taiwan 显示文摘 | Kuo C T Shin H Y Hong H F | 2009 | Renewable Energy2009，34，8： | 1 |
| 6 | Load Factor Calibration for the Proposed 2005 Edition of the National Building Code for Canada: Companion-action Load Combinations 显示文摘 | Bartlett F M Hong H P Zhou W | 2003 | Canadian Journal of Civil Engineering2003，，30： | 1 |
| 7 | Physical and chemical properties of a new root - end filling material 显示文摘 | Torabinejad M Hong CU McDonald F | 1995 | J Endod1995，21，7： | 1 |
| 8 | Determination methods of Rehmanniae Radix by HPLC 显示文摘 | Zhu M F Hong Seon-Pyo Kim Chungsook | 2003 | Korea J Herbology2003，18，3： | 1 |
| 9 | Electric signal detection at the early stage of laser ablation in air显示文摘 | Lu Y F Hong M H | 1999 | J Appl Phys1999，86，5： | 1 |
| 10 | Forecasting regional electricity load based on recurrent support vector machines with genetic algorithms 显示文摘 | Pal P F Hong W C | 2005 | Electric Power Systems Research2005，74，3： | 1 |
| 11 | BnC15 and BnATA20,the different putative components,control anther development in Brassica napus 显示文摘 | Wan L L Hu Q Hong D F | 2012 | Gene2012，507，1： | 1 |
| 12 | Physiological and biochemical effects of Allelo-chemical ethyl 2-methyl acetoacetate (EMA) on cyanobacterium Microcystis aeruginosa 显示文摘 | Hong Y Hu H Y Li F M | 2008 | Ecotoxicology and Environmental Safety2008，71，2： | 1 |
| 13 | Tumor-associated macrophages predict inferior outcomes in classic Hodgkin lymphoma: a correla- tive study from the E2496 Intergroup trial显示文摘 | Tan KL Scott DW Hong F | 2012 | Blood2012，120，16： | 1 |
| 14 | Plasma treatments of indium tin oxide anodes in carbon tetrafluorinde( CF4 )/oxygen( 02 )to im- prove the performance of organic light-emitting diodes显示文摘 | CHAN I M HONG F C | 2003 | Thin Solid Films2003，444，： | 1 |
| 15 | Characterization and properties of a novel organic inorganic hybrid based on hyperbranched aliphatie polyester prepared via sol-gel process显示文摘 | ZOU J H SHI W F HONG X Y | 2005 | Composites: Part A2005，36，： | 1 |
| 16 | Cooperative communications in resource-constrained wireless networks 显示文摘 | HONG Y W I-tUANG W J CHIU F H | 2007 | IEEE Signal Processing Magazine2007，24，3： | 1 |
| 17 | A modified cellular automaton model for the simulation of dendritic growth in solidification of alloys 显示文摘 | ZHU M F Hong C P | 2001 | ISIJ International2001，41，5： | 1 |
| 18 | A Modified Cellular Automaton Model for the Simulation of Dendritic Growth in Solidification of Alloy 显示文摘 | M F Zhu J M Kim C P Hong | 2001 | ISIJ2001，41，： | 1 |
| 19 | Analysis of beta- lactamase in mult-resistant Pseudomonas aeruginosa 显示文摘 | JIANG X F HONG X H SUN JY | 2002 | Chin J Microbiol Immunol2002，22，： | 1 |
| 20 | Capacity Evaluation of Statnamic Tested Long Piles 显示文摘 | LIN S S HONG J L LEE W F | 2004 | Soil Dynamics and Earthquake Engineering2004，24，11： | 1 |
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