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| 1 | Comparison of perceived pain and patients’ satisfaction with traditional local anesthesia and single tooth anesthesia: A randomized clinical trial显示文摘BACKGROUND Contemporary innovations in the area of local anesthesia have attempted to provide an absolutely pain free experience for patients.Since the introduction of Computer-Controlled Local Anesthetic Delivery Systems to dentistry,many studies have compared its efficacy and safety to conventional anesthesia.However,very few studies have compared single tooth anesthesia(STA)and traditional local anesthesia.AIM To compare pain rating,changes in blood pressure,and heart rate during the local anesthetic injection.The secondary objectives were to measure the patients’level of satisfaction and the differences in anesthetic efficiency between the STA system and traditional local infiltration.METHODS A randomized controlled trial was conducted and a total of 80 patients with dental restorative needs were enrolled for the study.The patients were evaluated for their general physical status and oral clinical findings before enrollment.Information regarding perceived pain,changes in heart rate and blood pressure,and patients’satisfaction was collected using an electronic data form and was analyzed using paired and unpaired t-tests.RESULTS No significant difference was noted in perceived pain(P=0.59)and systolic blood pressure(P=0.09)during anesthetic injection using both traditional and STA techniques.STA patients had a significantly higher heart rate during anesthesia,although a statistically significant difference was noted among the traditional anesthesia and the STA groups even before anesthesia.During the restorative procedure,less pain was perceived by STA patients on the Wong-Baker FACES pain scale,which was statistically significant(P<0.001).Analyses of post-procedure patient responses showed that STA patients had a significantly better treatment experience and preferred to have the same method of injection in the future(P=0.04).CONCLUSION STA system can provide less painful and more comfortable restorative treatment procedures in comparison to the traditional infiltration technique. | Mohammad I Al-Obaida Mehdiya Haider Rawan Hashim Wafa AlGheriri Sree Lalita Celur Samar A Al-Saleh Ebtissam M Al-Madi | 2019 | World Journal of Clinical Cases2019，7，19： | 8 |
| 2 | Ascites and alpha-fetoprotein improve prognostic performance of Barcelona Clinic Liver Cancer staging显示文摘AIM: To assess how ascites and alpha-fetoprotein(AFP) added to the Barcelona Clinic Liver Cancer(BCLC) staging predict hepatocellular carcinoma survival.METHODS: The presence of underlying cirrhosis, ascites and encephalopathy, Child-Turcotte-Pugh(CTP) score, the number of nodules, and the maximum diameter of the largest nodule were determined at diagnosis for 1060 patients with hepatocellular carcinoma at a tertiary referral center for liver disease in Egypt. Demographic information, etiology of liver disease, and biochemical data(including serum bilirubin, albumin, international normalized ratio, alanine and aspartate aminotransferases, and AFP) were evaluated. Staging of the tumor was determined at the time of diagnosis using the BCLC staging system; 496 patients were stage A and 564 patients were stage B. Patients with mild ascites on initial ultrasound, computed tomography, or clinical examination, and who had a CTP score ≤ 9 were included in this analysis. All patients received therapy according to the recommended treatment based on the BCLC stage, and were monitored from the time of diagnosis to the date of death or date of data collection. The effect of the presence of ascites and AFP level on survival was analyzed.RESULTS:At the time the data were censored,123/496(24.8%)and 218/564(38.6%)patients with BCLC stages A and B,respectively,had died.Overall mean survival of the BCLC A and B patients during a three-year follow-up period was 31 mo[95%confidence interval(95%CI):29.7-32.3]and 22.7mo(95%CI:20.7-24.8),respectively.The presenceof ascites,multiple focal lesions,large tumor size,AFP level and CTP score were independent predictors of survival for the included patients on multivariate analysis(P<0.001).Among stage A patients,18%had ascites,33%had AFP≥200 ng/m L,and 8%had both.Their median survival in the presence of ascites was shorter if AFP was≥200 ng/m L(19 mo vs 24 mo),and in the absence of ascites,patients with AFP≥200 ng/m L had a shorter survival(28mo vs 39 mo).For stage B patients,survival for the corresponding groups was 12,18,19 and 22 mo.The one-,two-,and three-year survival rates for stage A patients without ascites and AFP<200 ng/m L were94%,77%,and 71%,respectively,and for patients with ascites and AFP≥200 ng/m L were 83%,24%,and 22%,respectively(P<0.001).Adding ascites and AFP≥200 ng/m L improved the discriminatory ability for predicting prognosis(area under the curve,0.618vs 0.579 for BCLC,P<0.001).CONCLUSION:Adding AFP and ascites to the BCLC staging classification can improve prognosis prediction for early and intermediate stages of hepatocellular carcinoma. | Asmaa I Gomaa Alzhraa Al-Khatib Wael Abdel-Razek Mohammed Saad Hashim Imam Waked | 2015 | World Journal of Gastroenterology2015，21，18： | 3 |
| 3 | Impact and risk factors of post-stroke bone fracture显示文摘Bone fracture occurs in stroke patients at different times during the recovery phase, prolonging recovery time and increasing medical costs. In this review, we discuss the potential risk factors for post-stroke bone fracture and preventive methods. Most post-stroke bone fractures occur in the lower extremities, indicating fragile bones are a risk factor. Motor changes, including posture, mobility, and balance post-stroke contribute to bone loss and thus increase risk of bone fracture. Bone mineral density is a useful indicator for bone resorption, useful to identify patients at risk of post-stroke bone fracture. Calcium supplementation was previously regarded as a useful treatment during physical rehabilitation. However, recent data suggests calcium supplementation has a negative impact on atherosclerotic conditions. Vitamin D intake may prevent osteoporosis and fractures in patients with stroke. Although drugs such as teriparatide show some benefits in preventing osteoporosis, additional clinical trials are needed to determine the most effective conditions for post-stroke applications. | Kang Huo Syed I Hashim Kimberley LY Yong Hua Su Qiu-Min Qu | 2016 | World Journal of Experimental Medicine2016，6，1： | 2 |
| 4 | Local stability of period two cycles of second order rational difference equation 显示文摘 | S Atawna R Abu-Saris I Hashim | 2012 | Discrete Dynamics in Nature and Society2012，，： | 1 |
| 5 | Inhibitory effects of olive oil phenolics on invasion in human colon adenocarcinoma cells in vitro显示文摘 | Hashim Z H Rowland I R Mcglynn H | 2008 | Int J Cancer2008，122，3： | 1 |
| 6 | Effect of heat treatment on the drilling performance of aluminium/SiC MMC 显示文摘 | Barnes S Pashby I R Hashim A B | 1999 | Applied Composite Materials1999，6，： | 1 |
| 7 | Direct FAME synthesis for rapid total lipid analysis from fish oil and cod liver oil显示文摘 | INDARTI E MAJID M I HASHIM R | 2005 | J Food Compost Anal2005，18，： | 1 |
| 8 | Comparison of homotopy analysis method and homotopyperturbation method for purely nonlinear fin-type problems显示文摘 | Chowdhury M S H Hashim I Abdulaziz O | 2009 | Comm in Nonlinear Sci and Numer Sim2009，14，2： | 1 |
| 9 | On a new reliable modification of homotopy analysis method 显示文摘 | Bataineh A S Noorani M S M Hashim I | 2009 | Comm in Nonlinear Sci and Numer Sim2009，14，2： | 1 |
| 10 | Assessment of dry matter and protein digestibilities of selected raw ingredients by discus fish (Symphysondon acquifasciate) using in vivo and in vitro methods 显示文摘 | Chong R Hashim I M | 2002 | Aqua Nutr2002，8，： | 1 |
| 11 | Modified homotopy analysis method for solving systems of second-order BVPs显示文摘 | Bataineh A S Noorani M S M Hashim I | 2009 | Comm in Nonlinear Sci and Numer Sim2009，14，2： | 1 |
| 12 | Solving systems of ODEs by homotopy analysis method显示文摘 | Bataineh A S Noorani M S M Hashim I | 2008 | Comm in Nonlinear Sci and Numer Sim2008，13，10： | 1 |
| 13 | Adaptive pseudospectral methods for solving constrained linear and nonlinear time-delay optimal control problems 显示文摘 | Maleki M Hashim I | 2014 | Journal of the Franklin Institute2014，351，2： | 1 |
| 14 | Inhibitory effects of olive oil phenolics on invasion in human colon adenocarcinoma cells in vitro显示文摘 | Hashim Y Z Rowland I R Mc Glynn H | 2008 | Int J Cancer2008，122，3： | 1 |
| 15 | Lard detection based on fatty acids profile using comprehensive gas chromatography hyphenated with time-of-flight mass spectrometry显示文摘 | DIAS I MUSTAFA Y B M HASHIM D M | 2010 | Food Chemistry2010，122，4： | 1 |
| 16 | Insulin and ketone responses to ingestion of medium and longchain triglycerides in man显示文摘 | Pi-Sunyer F X Hashim S A Van I T B | 1969 | Diabetes1969，18，： | 1 |
| 17 | Series solution of flow over nonlinearly stretching sheet with chemical reactionand magnetic field显示文摘 | Kechil S A Hashim I | 2008 | Physics Letters A2008，372，13： | 1 |
| 18 | Application of ho- motopy-perturbation method to fractional IVPs显示文摘 | Abdulaziz O Hashim I Momani S | 2008 | Jour- nal of Computational & Applied Mathematics2008，216，2： | 1 |
| 19 | Homotopy analysis method for fractional IVPs显示文摘 | Hashim I Abdulaziz O Momani S | 2009 | Communications in Non- linear Science & Numerical Simulation2009，14，3： | 1 |
| 20 | Techniques for vibration control of a flexible robot manipulator显示文摘 | Mohamed Z Chee A K Mohd Hashim A W I | 2006 | Robotica2006，24，： | 1 |
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