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| 1 | How significant is the association between metabolic syndrome and prevalence of colorectal neoplasia?显示文摘The incidence and prevalence of metabolic syndrome(MS) and colorectal cancer(CRC) has been rising in developed countries. The association between these two diseases has been widely studied and reported. Less evidence is available about the relationship between MS and CRC precancerous lesions(adenomatous polyps, adenomas). The aim of this paper is to present an overview of our scientific understanding of that topic and its implication in clinical practice. One of the principal goals of current CRC secondary prevention efforts is to detect and remove the precancerous lesions in individuals with an average CRC risk to prevent the development of invasive cancer. MS is not currently considered a high-risk CRC factor and is therefore not included in the guidelines of organized screening programs. However, in light of growing scientific evidence, the approach to patients with MS should be changed. Metabolic risk factors for the development of adenomas and cancers are the same- obesity, impaired glucose tolerance, dyslipidemia, hypertension, cardiovascular diseases and diabetes mellitus type 2. Therefore, the key issue in the near future is the development of a simple scoring system, easy to use in clinical practice, which would identify individuals with high metabolic risk of colorectal neoplasia and would be used for individual CRC secondary prevention strategies. Currently, such scoring systems have been published based on Asian(Asia-Pacific Colorectal Screening Score; APCS) and Polish populations. | Stepan Suchanek Tomas Grega Ondrej Ngo Gabriela Vojtechova Ondrej Majek Petra Minarikova Nagyija Brogyuk Bohus Bunganic Bohumil Seifert Ladislav Dusek Miroslav Zavoral | 2016 | World Journal of Gastroenterology2016，22，36： | 10 |
| 2 | Brain perfu- sion in asphyxiated newborn8 treated with therapeutic hypothermia 显示文摘 | Wintermark P Hansen A Gregas M C | 2011 | AJNR Am J Neuroradiol2011，32，11： | 1 |
| 3 | Watershed strokes after cardiac surgery : diagnosis, etiology, and outcome 显示文摘 | Gottesman RF Sherman PM Grega MA | 2006 | Stroke2006，37，9： | 1 |
| 4 | Is there cognitive decline 1 year after CA BG? Comparison with surgical and nonsurgical controls 显示文摘 | McKhann GM Grega MA Borowicz LM | 2005 | Neurology2005，65，5： | 1 |
| 5 | Elevated cerebral pressure passivity is associated with prematurity-related intracranial hemorrhage显示文摘 | O'Leary H Gregas M C Limperopoulos C | 2009 | Pediatrics2009，124，1： | 1 |
| 6 | SERS-based plasmonic nanobiosensing in single living cells 显示文摘 | SCAFFIDI J P GREGAS M K SEEWALDT V | 2009 | AnalBioanal Chem2009，393，19： | 1 |
| 7 | Apoferritin protein cages: A novel drug nanocarrier for photodynamie therapy 显示文摘 | Yah Fei Zhang Zhang Gregas Molly | 2008 | Chemical Communications2008，38，： | 1 |
| 8 | Cognitive changes 5 years after coronary artery bypass grafting:is there evidence of late decline?显示文摘 | Selnes OA Royall RM Grega MA | 2001 | Archives of Neurology2001，58，4： | 1 |
| 9 | Stroke and encephalopathy after cardiac surgery:an update显示文摘 | Grega MA Borowicz LM Jr | 2006 | Stroke2006，37，2： | 1 |
| 10 | Association between hypotersion,low ejection fraction and cognitive performance in cardiac patients显示文摘 | Gottesman RF Grega MA Bailey MM | 2010 | Behav Neurol2010，22，12： | 1 |
| 11 | Circuit breaker model for digital simulation based on Mayr's and Cassie' s differential arc equations 显示文摘 | Grega Bizjak Peter Zunko Dusan Povh | 1995 | IEEE Transactions on Power Delivery1995，10，3： | 1 |
| 12 | Elevated cerebral pressure passivity is associated with prematurity- related intracranial hemorrhage 显示文摘 | O'Leary H Gregas MC Limperopoulos C | 2009 | Pediatrics2009，124，1： | 1 |
| 13 | Association between hypotension,low ejection fraction and cognitive performance in cardiac patients显示文摘 | Gottesman RF Grega MA Bailey MM | 2010 | Behav Neurol2010，22，： | 1 |
| 14 | Watershed strokes after cardiac surgery:diagnosis,etiology,and outcome显示文摘 | Sherman PM Grega MA | 2006 | Strokem2006，37，9： | 1 |
| 15 | Surlaee-enhanced Raman scattering detection and tracking of nanoprobes: enhanced uptake and nuclear targeting in single eells 显示文摘 | GREGAS M K SCAFF1DI J P LAULY B | 2010 | Appl Spectrosc2010，64，8： | 1 |
| 16 | Watershed strokesafter cardiac surgery : diagnosis, etiology,and outcome 显示文摘 | Gottesman RF Sherman PM Grega MA | 2006 | Stroke2006，37，9： | 1 |
| 17 | Encephalopathy and stroke after coronary artery bypass grafting: incidence, consequences, and prediction 显示文摘 | McKhann GM Grega MA Borowicz LM Jr | 2002 | Arch Neuro2002，59，： | 1 |
| 18 | Encephalopathy and stroke after coronary artery bypass grafting:incidence,consequences,and prediction显示文摘 | Grega MA Borowicz LM | 2002 | Arch Neurol2002，59，9： | 1 |
| 19 | Digital Control of a tank system显示文摘 | Grega W A Maciejczyk | 1994 | IEEE Transactions on Education1994，37，3： | 1 |
| 20 | Cognitive changes with coronary artery disease: a prospective study of coronary artery bypass graft patients and nonsurgical controls显示文摘 | SELNES O A GREGA M A BOROWICZ L M Jr | 2003 | Ann Thorac Surg2003，75，5： | 1 |
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