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| 1 | Serum leptin levels and insulin resistance are associated with gallstone disease in overweight subjects显示文摘AIM: To establish an association between the serum leptin levels and the development of gallstone disease (GD).METHODS: We carried out a non-matched case-controlled study in a university hospital in Mexico City. Two hundred and eighty-seven subjects were included: 97 cases with gallstones and 190 controls. Body mass index (BMI), fasting plasma leptin, insulin, serum lipid, and lipoprotein levels were measured. Insulin resistance was calculated by homeostasis model assessment (HOMA-IR). Unconditional logistic regression analysis (univariate and multivariate)stratified by BMI was used to calculate the risk of GD.RESULTS: The multivariate conditional regression analysis revealed a model for those patients with BMI <30. The selected variables in the model were HOMA-IR index with OR = 1.31, P= 0.02 and leptin higher than median with OR = 2.11, P= 0.05. In the stratum of BMI ≥30, we did not find a useful model.CONCLUSION: We concluded that insulin resistance and the development of GD appears to be associated with serum leptin levels in subjects with overweight, but not in obese subjects with similar metabolic profiles. | Nahum Méndez-Sánchez Luisa B Bermejo-Martínez Yolanda Vi(n|~)als Norberto C Chavez-Tapia Irina Vander Graff Guadalupe Ponciano-Rodríguez Martha H Ramos Misael Uribe | 2005 | World Journal of Gastroenterology2005，11，39： | 11 |
| 2 | Vitamin D and macular thickness in the elderly:an optical coherence tomography study显示文摘 | Graffe A Beauchet O Fantino B | 2014 | Invest Oph- thalmol Vis Sci2014，55，8： | 1 |
| 3 | Structural effects in the indanedione skeleton for the design of low intensity 300-500 nm light sensitive initiators 显示文摘 | XIAO P DUMUR F GRAFF B | 2014 | Macromolecules2014，47，： | 1 |
| 4 | Blue light sensitive dyes for various photopolymerization reactions:naphthalim- ide and naphthalic anhydride derivatives 显示文摘 | XIAO P DUMUR F GRAFF B | 2014 | Macromole- cules2014，47，： | 1 |
| 5 | Measurements of diagnostic examination performance and correlation analysis using microvascular leakage, cerebral blood volume, and blood flow derived from 3T dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging in glial tumor grading显示文摘 | Server A Graff B A Orheim T E | 2011 | Neuroradiology2011，53，6： | 1 |
| 6 | eIF4E activation is commonly elevated in advanced human prostate cancers and signifi- cantly related to reduced patient survival显示文摘 | Graff J R Konicek B W Lynch R L | 2009 | Cancer Res2009，69，9： | 1 |
| 7 | Alterations in DNA methylation:A fundamental aspect of neoplasia显示文摘 | BAYLIN S B HERMAN J G GRAFF J R | 1998 | Adv Cancer Res1998，72，1： | 1 |
| 8 | The gouging phenomenon betweenmetal surfaces at very high sliding speeds 显示文摘 | Graff K F Dettloff B 13 | 1969 | Wear1969，14，： | 1 |
| 9 | Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands 显示文摘 | Herman J G Graff J R Myohanen S Nelkin B D Baylin S B | 1996 | Proc Natl Acad Sci USA1996，93，： | 1 |
| 10 | Targeting the eukaryotic traslation initiation factor 4E for cancer thera- py 显示文摘 | Graff J R Konicek B W Carter J H | 2008 | Cancer Res2008，68，3： | 1 |
| 11 | Targeting the eukaryotic translation initiation factor 4E for cancer therapy显示文摘 | GRAFF J R KONICEK B W CARTER J H | 2008 | Cancer Res2008，68，3： | 1 |
| 12 | Development of a digital array radar (DAR)显示文摘 | CANTRELL B GRAFF J D WILLWERTH F | 2002 | IEEE AESS System Magazine2002，17，3： | 1 |
| 13 | Integrin-linked kinase expression increases with increases with prostate tumor grade显示文摘 | Graff J R Deddens J A Konicek B W | 2001 | ClinCancerRes2001，7，7： | 1 |
| 14 | Materials for multifunctional balloon catheters with capabilities in cardiac electrophysiological mapping and ablation therapy显示文摘 | Kim D H Lu N Ghaffari R Kim Y S Lee S P Xu L Wu J Kim R H Song J Liu Z Viventi J Graff B D Elolampi B Mansour M Slepian M J Hwang S Moss J D Won S M Huang Y Rogers J A | 2011 | Nature Materials2011，10，4： | 1 |
| 15 | Alterations in DNA methylation: A fundamental aspect of neoplasia 显示文摘 | BAYLIN S B HERMAN J G GRAFF J R | 1998 | Adv Cancer Res1998，72，1： | 1 |
| 16 | Iron repressible outer membrane proteins of Helicobacter pylori involved in heme uptake显示文摘 | WORST D J OTTO B R de GRAFF J | 1995 | Infect Immune1995，63，： | 1 |
| 17 | ll,K as a potential marker gene to ascertain specific adenoearcinoma cell mRNA isolation from frozen prostate biopsy tissue section显示文摘 | GRAFF J R DEDDENS J A KONICEK B W | 2005 | International Journal of Oncology2005，26，6： | 1 |
| 18 | Integrin-linked kinase expression increases with prostate tumor grade显示文摘 | GRAFF J R DEDDENS J A KONICEK B W | 2001 | Clin Cancer Res2001，7，7： | 1 |
| 19 | The gouging phenomenon betweenmetal surface at very high sliding speeds 显示文摘 | Graff K F Dettloff B B | 1969 | Wear1969，14，2： | 1 |
| 20 | Influence of the 5`-noncoding region of hepatitis A virus strain GBM on its growth in different cell lines显示文摘 | Graff J Norman A Flehmig B | 1997 | J Gen Virol1997，78，： | 1 |
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