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| 1 | Adjuvant dendritic cell-based tumour vaccination for children with malignant brain tumours显示文摘 | Ardon H De Vleeschouwer S Van Calenbergh F Claes L Kramm CM Rutkowski S Wolff JE Van Gool SW. | 2010 | 中国神经肿瘤杂志2010，8，1： | 3 |
| 2 | CD28/CTLA-4/B7 and CD40/CD40L costimulation and activation of regulatory T cells显示文摘Costimulatory signals are crucial for T cell activation. Attempts to block costimulatory pathways have been effective in preventing unwanted immune reactions. In particular, blocking the CD28/cytotoxic T lymphocyte antigen(CTLA)-4/B7 interaction(using CTLA-4Ig) and the CD40/CD40 L interaction(using anti-CD40 L antibodies) prevents T cell mediated autoimmune diseases, transplant rejection and graft vs host disease in experimental models. Moreover, CTLA-4Ig is in clinical use to treat rheumatoid arthritis(abatacept) and to prevent rejection of renal transplants(belatacept). Under certain experimental conditions, this treatment can even result in tolerance. Surprisingly, the underlying mechanisms of immune modulation are still not completely understood. We here discuss the evidence that costimulation blockade differentially affects effector T cells(Teff) and regulatory T cells(Treg). The latter are required to control inappropriate and unwanted immune responses, and their activity often contributes to tolerance induction and maintenance. Unfortunately, our knowledge on the costimulatory requirements of Treg cells is very limited. We therefore summarize the current understanding ofthe costimulatory requirements of Treg cells, and elaborate on the effect of anti-CD40 L antibody and CTLA-4Ig treatment on Treg cell activity. In this context, we point out that the outcome of a treatment aiming at blocking the CD28/CTLA-4/B7 costimulatory interaction can vary with dosing, timing and underlying immunopathology. | Isabel T Vogel Stefaan W Van Gool Jan L Ceuppens | 2014 | World Journal of Immunology2014，4，2： | 3 |
| 3 | An adaptive color-based particle filter显示文摘 | Nummiaro K Koller-Meier E Van Gool L | 2003 | hnage Vision Comput2003，21，1： | 1 |
| 4 | Matching widely separated views based on affine invariant regions 显示文摘 | TUYTELAARS T Van GOOL L | 2004 | International Journal on Computer Vision2004，59，1： | 1 |
| 5 | Fast prism: branch and bound hough transform for object class detection显示文摘 | Lehmann A Leibe B and Gool L | 2011 | International Journal of Computer Vision2011，94，2： | 1 |
| 6 | SURF: Speeded up robust features显示文摘 | BAY H TUYTELAARS T GOOL L | 2008 | Computer Vision and Image Understanding2008，110，3： | 1 |
| 7 | Speeded-up robust features (SURF)显示文摘 | Bay H Ess A Tuvtellars T Gool L V | 2008 | Computer Vision and Image Understanding2008，110，： | 1 |
| 8 | An adaptive color based particle filter 显示文摘 | K Nummiaro E Koller-Meier L Van Gool | 2003 | Image and Vision Computing (S0262-8856)2003，21，1： | 1 |
| 9 | The pascal visual object classes (VOC) challenge显示文摘 | Everingham M Van Gool L Williams C | 2009 | International Journal of Com- puter Vision2009，88，2： | 1 |
| 10 | An adaptive color-based particle fitter显示文摘 | Nummiaro K Koller-Meier E Van Gool L | 2003 | Image and Vision Computing2003，21，1： | 1 |
| 11 | An Adaptive Color-based Particle Filter显示文摘 | Nummiaro K Koller-Meier E Gool L V | 2003 | Image and Vision Computing2003，21，1： | 1 |
| 12 | An adaptive color-based particle filter显示文摘 | Nummiaro K Roller-Meier E Van Gool L | 2003 | Image and Vision Computing2003，21，1： | 1 |
| 13 | Speeded-up robust features (SURF)显示文摘 | Bay H Tuytelaars T Van Gool L | 2008 | Computer Vision and Image Understanding2008，110，3： | 1 |
| 14 | Matching widely separated views based on affinely invariant neighbourhoods显示文摘 | TUYTELAARS T VAN GOOL L | 2004 | International Journal of Computer Vision2004，59，1： | 1 |
| 15 | Matching widely separated views based on affine invariant regions显示文摘 | Tuytelaars T Gool L V | 2004 | International Journal of Computer Vision2004，59，1： | 1 |
| 16 | An Adaptive Color-based Particle Filter显示文摘 | Nummiaro K Meier E K Gool L V | 2003 | Image and Vision Computing2003，21，1： | 1 |
| 17 | Matching widely separated views based on affine invariant regions 显示文摘 | Tuytelaars T Gool L V | 2004 | International Journal of Computer Vision(S0920-5691)2004，59，1： | 1 |
| 18 | An Aadaptive Color-based Particle Filter显示文摘 | Nummiaro K Koller-Meier E Van Gool L | 2003 | Image and Vision Computing2003，，1： | 1 |
| 19 | Smart particle filtering for high-dimensional tracking 显示文摘 | Bray M Koller-Meier E Gool L V | 2007 | Computer Vision and Image Understanding2007，106，1： | 1 |
| 20 | Self-calibration and metric reconstruction in spite of varying and unknown internal camera parameters 显示文摘 | Pollefeys M Koch R van Gool L | 1999 | International Journal of Computer Vision1999，32，1： | 1 |
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