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| 1 | Impact of osteoporosis in dental implants:A systematic review显示文摘AIM: To assess the failure and bone-to-implant contact rate of dental implants placed on osteoporotic subjects. METHODS: Extensive examination strategies were created to classify studies for this systematic review. MEDLINE(via Pub Med) and EMBASE database were examined for studies in English up to and including May 2014. The examination presented a combination of the MeS H words described as follow: 'osteoporosis' or 'osteopenia' or 'estrogen deficiency' AND 'implant' or 'dental implant' or 'osseointegration'. Assessment of clinical and/or histological peri-implant conditions in osteoporosis subjects treated with titanium dental implants. The examination included a combination of the MeS H terms described as follow: 'osteoporosis' or 'osteopenia' or 'estrogen deficiency' AND 'implant' or 'dental implant' or 'osseointegration'.RESULTS: Of 943 potentially eligible articles, 12 were included in the study. A total of 133 subjects with osteoporosis, 73 subjects diagnosed with osteopenia and 708 healthy subjects were assessed in this systematic review. In these subjects were installed 367, 205, 2981 dental implants in osteoporotic, osteopenic and healthy subjects, respectively. The failure rate of dental implant was 10.9% in osteoporotic subjects, 8.29% in osteopenic and 11.43% in healthy ones. Bone-to-implant contact obtained from retrieved implants ranged between 49.96% to 47.84%, for osteoporosis and non-osteoporotic subjects. CONCLUSION: Osteoporotic subjects presented higher rates of implant loss, however, there is a lower evidence to strengthen or refute the hypothesis that osteoporosis may have detrimental effects on bone healing. Consequently, final conclusions regarding the effect of osteoporosis in dental implant therapy cannot be made at this time. There are no randomized clinical trial accessible for evaluation and the retrospectivenature of the evaluated studies shall be taken in account when interpreting this study. | Gabriela Giro Leandro Chambrone Abrao Goldstein Jose Augusto Rodrigues Elton Zenóbio Magda Feres Luciene Cristina Figueiredo Alessandra Cassoni Jamil Awad Shibli | 2015 | World Journal of Orthopedics2015，6，2： | 11 |
| 2 | Nteropathogenic Escherichia coli mediate adherence to epithelial cells 显示文摘 | Giro'n JA AG Torres E Freer | 2002 | Mol Microbiol2002，44，： | 1 |
| 3 | Interrelationships among chromosome aneuploidy, promoter hypermethylation, and protein expression of the CDKN2A gene in individuals from northern Brazil with gastric adenocarcinoma显示文摘 | Lima EM Khayat AS Giro MH | 2007 | Cancer Genet Cytogenet2007，179，1： | 1 |
| 4 | Effect of 17 beta - estra- diol and alendronate on the removal torque of osseointegrated tita- nium implants in ovariectomized rats 显示文摘 | Giro G Sakakura CE Gongalves D | 2007 | J Pefodantol2007，78，7： | 1 |
| 5 | Flagellin of enteropathogenic Escherichia coli stimulates interleukin- 8 production in T84 cells 显示文摘 | Zhou X JA Giro'n AG Torres | 2003 | Infect Immun2003，71，： | 1 |
| 6 | Bacteria-derived hydrogen sulfide promotes IL-8 production from epithelial ceUs显示文摘 | Chen W Kajiya M Giro G | 2010 | Biochem Biophys Res Commun2010，391，1： | 1 |
| 7 | Human pulp response after an adhesive system application in deep cavities显示文摘 | Hebling J Giro EM Costa CA | 1999 | J Dent1999，27，8： | 1 |
| 8 | Molecular characterization of the dopamine transporter显示文摘 | Giros B Caron M G | 1993 | Trends Pharmacol Sci1993，14，2： | 1 |
| 9 | Biocompatibility of an ad-hesive system applied to exposed human dental pulp 显示文摘 | Hebling J Giro EM Costa CA | 1999 | J Endod1999，25，10： | 1 |
| 10 | The third dopamine receptor (D3) as a novel target for antipsychotics显示文摘 | Sokoloff P Martres MP Giros B | 1992 | Biochem Pharmacol1992，43，4： | 1 |
| 11 | The effect of implant design on insertion torque and immediate micromotion显示文摘 | Freitas AC Jr Bonfante EA Giro G | 2012 | Clin Oral Implants Res2012，23，1： | 1 |
| 12 | hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter显示文摘 | Giros B Jaber M Jones SR | 1996 | Nature1996，379，6566： | 1 |
| 13 | Human pulp response after an adhesive system application in deep cavities显示文摘 | Hebling J Giro EM Costa CA | 1999 | J Dent1999，27，8： | 1 |
| 14 | Molecular characterization of the dopamine transporter显示文摘 | Giros B Caron MG | 1993 | Trends in Pharmoco Sci1993，14，2： | 1 |
| 15 | The dopamine transporter:Acrucial component regulating dopamine transmission显示文摘 | Jaber M Jones S Giros B | 1997 | MovementDisord1997，12，： | 1 |
| 16 | The dopamine transporter: a cru- cial component regulating dopamine transmission 显示文摘 | Jaber M Jones S Giros B | 2004 | Mov Disord2004，12，： | 1 |
| 17 | Influence of estrogen deficiency and its treatment with alendronate and estrogen on bone density around osseointegrated implants: radiographic study in female rats 显示文摘 | Giro G Goncalves D Sakakura CE | 2008 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod2008，105，2： | 1 |
| 18 | Influence of es- trogen deficiency and its treatment with alendronate and estrogen on bone density around osseointegrated implants: Radiographic study in female rats显示文摘 | Giro G Gonqalves D Sakakura CE | 2008 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod2008，105，2： | 1 |
| 19 | Automated maneuvering decisions for air-to-air combat显示文摘 | GIRO CARBONE | 1987 | AIAA-87-23931987，，： | 1 |
| 20 | A three dimensional tire model for steady-state simulations of vehicles 显示文摘 | Giro G Nikravesh P E | 1993 | SAE1993，102，2： | 1 |
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