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93篇 您的检索式:作者名="Giacca"
    题名 作者 年代 出处 被引量
1Different mechanisms for cellular internalization of the ttlV - 1 Tat - derived cell peptide and recombinant proteins fused to Tat显示文摘Silhol M Tyagi M Giacca M 2002Eur J Biochem2002,269,2:1
2HIV Tat, its TARgets and the control of viral gene expression显示文摘Brigati C Giacca M Noonan DM 2003FEMS Microbiol Lett2003,220,1:1
3Differential effects of IGF-1 and insulin on glucoregulation and fat metabolism in depancreatized dogs显示文摘Giacca A Gupta R Efendic S 1990Diabetes1990,39,:1
4Lipid-induced pancreatic β-cell dysfunction: focus on in vivo studies 显示文摘Giacca A Xiao C Oprescu AI 2011Am J rhysiol Endocrinol Metab2011,300,2:1
5VEGF gene therapy: therapeutic angiogenesis in the clinic and beyond显示文摘Giacca M Zacchigna S 2012Gene Ther2012,19,6:1
6The HIV-1 Tat protein: a multifaceted target for novel therapeutic opportunities 显示文摘GIACCA M 2004Curr Drug Targets Immune Endocr Metabol Disord2004,4,4:1
7The HIV-1 Tat protein:a multifaceted target for novel therapeutic opportunities显示文摘Giacca M 2004Curr Drug Targets Immune Endocr Metabol Disord2004,4,:1
8Reversible acetylation regulates vascular endothelial growth factor receptor-2 activity显示文摘酷氨酸 kinase 受体(VEGFR2 ) 脉管的 endothelial 生长因素受体 2 是 angiogenesis 的一个关键管理者。VEGFR2 在在 kinaseinsert 领域形成稠密的簇的四离氨酸残余两个都是在 endothelial 房间的 acetylated,在一个单身者,离氨酸在受体激活环定位的 Herewe 表演。这些修正在动态 controlof 下面是 acetyltransferase p300 和二 deacetylases HDAC5 和 HDAC6。我们实质上表明那 VEGFR2 acetylation regulatesreceptor phosphorylation。特别地, VEGFR2 acetylation 显著地改变受体 phosphorylationafter ligand 绑定的动力学,允许受体 phosphorylation 并且在在激活循环的离氨酸的那 acetylation 贡献的有模拟显示的 VEGF.Molecular 动力学的延长刺激之上的细胞内部的发信号 transitionto 一个开的活跃状态,在哪个酷氨酸 phosphorylation 被 kinase 目标残余的更好的暴露赞成。Thesefindings 显示由 acetylation 的那 translational 以后修正是直接影响 VEGFR2function 的批评机制。Annalisa Zecchin Lucia Pattarini Maria Ines Gutierrez Miguel Mano Antonello Mai Sergio Valente Mike P. Myers Sergio Pantano Mauro Giacca 2014Journal of Molecular Cell Biology2014,8,2:1
9Hypoxie gene expression and metastasis显示文摘LE QT DENKO NC GIACCA AJ 2004Cancer Metastasis Rev2004,23,:1
10The HIV-1 Tat protein: a multifaceted target for novel therapeutic opportunities显示文摘Giacca M 2004Curr Drug Targets Immune Endocr Metabol Disord2004,4,4:1
11Increased responses of glucagon and glucose production to hypoglycemia with intraperitoneal versus subcutaneous insulin treatment显示文摘Wan CK Giacca A Matsuhisa M 2000Metabolism2000,49,8:1
12Transcellular trausfer of active HSV-1 thymidine kinase mediated by an 11-amino-acid peptide from HIV-1 Tat显示文摘Tasciotti E Zoppe M Giacca M 2003Cancer Gene Ther2003,10,1:1
13Effects of insulin on the vasculature显示文摘Breen DM Giacca A 2011Curr Vase Pharmacol2011,9,3:1
14Transcellular transfer of active HSV - 1 thymidine kinase mediated by an 11 - amino - acid peptide from HIV- 1 Tat显示文摘Tasciotti E Zoppe M Giacca M 2003Cancer Gene Ther2003,10,1:1
15The HIV-1 Tat protein: a multifaceted target for novel therapeutic opportunities 显示文摘Giacca M 2004Curr Drug Targets Immune Endocr Metabol Disord2004,4,:1
16Different mechanisms for cellular internalization of the HIV-1 Tat-derived cell penetrating peptide and recombinant proteins fused to Tat 显示文摘Silhol M Tyagi M Giacca M 2002Eur J Biochem2002,269,2:1
17Increased responses of glucagon and glucose production to hypoglycemia with intraperitoneal versus subcutaneous insulin treatment显示文摘Wan CK Giacca A Matsuhisa M 2000Metabolism2000,49,8:1
18Amino acid modification in the HIV- 1 Tat basic domain: insights from molecular dynamics and in vivo functional studies显示文摘 Tyagi M Giacca M 2002J Mol Biol2002,318,5:1
19Increased responses of glucagon and glucose production to hypoglycemia with intraperitoneal versus subcutaneous insulin treatment显示文摘Wan CK Giacca A Matsuhisa M 2000Metabolism2000,49,8:1
20Different mechanisms for cellular internalization of the HIV-1 TAT-derived cell penetrating peptide and recombinant proteins fused to TAT显示文摘Silhol M Tyagi M Giacca M 2002Eur J Biochem2002,269,2:1
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