|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Clinical and epidemiological characteristics of norovirus gastroenteritis among hospitalized children in Lebanon显示文摘AIM To assess the burden of norovirus(No V) and to determine the diversity of circulating strains among hospitalized children in Lebanon. METHODS Stool samples were collected from children presenting with acute gastroenteritis to six major hospitals in Lebanon. A total of 739 eligible stool samples, testing negative for diarrhea caused by rotavirus as a possible viral pathogen, were collected between January 2011 and June 2013. A standardized questionnaire including demographic, epidemiological and clinical observations was used at the time of hospitalization of children presenting with diarrhea. Viral RNA was extracted from stool samples followed by reverse transcription polymerase chain reaction and nucleotide sequencing of a fragment of the viral protein 1 capsid gene. Multiple sequence alignments were carried out and phylogenetic trees were constructed using the MEGA 6 software.RESULTS Overall, 11.2% of stool samples collected from children aged < 5 years tested positive for No V genogroups Ⅰ(GⅠ) and Ⅱ(GⅡ). GⅡ accounted for 10.6% of the gastroenteritis cases with only five samples being positive for GⅠ(0.7%). The majority of hospitalized children showed symptoms of diarrhea, dehydration, vomiting and fever. Upon sequencing of positive samples and based on their clustering in the phylogenetic tree, 4/5 of GⅠ gastroenteritis cases were designated GⅠ.3 and one case as GⅠ.4. GⅡ.4 was predominantly detected in stool of our study participants(68%). We report a JB-15/KOR/2008 GⅡ.4 Apeldoorn 2008-like variant strain circulating in 2011; this strain was replaced between 2012 and 2013 by a variant sharing homology with the Sydney/NSW0514/2012/AUS GⅡ.4 Sydney 2012 and Sydney 2012/FRA GⅡ.4 strains. We also report the co-circulation of non-GⅡ.4 genotypes among hospitalized children. Our data show that No V gastroenteritis can occur throughout the year with the highest number of cases detected during the hot months.CONCLUSION The majority of No V-associated viral gastroenteritis cases among our participants are attributable to GⅡ.4, which is compatible with results reported worldwide. | Nada M Melhem Hassan Zaraket Khalil Kreidieh Zeinab Ali Moza Hammadi Soha Ghanem Farah Hajar Amjad Haidar Adlette Inati Mariam Rajab Hassan Fakhouri Bassam Ghanem Ghassan Baasiri Ghassan Dbaibo | 2016 | World Journal of Gastroenterology2016，22，48： | 3 |
| 2 | Hydro gels o{ starch-g-(tert-butylacrylate) and starch-g- (n-bu tylacrylate) copolymers 显示文摘 | Fares M M El-faqeeh A S Ghanem H | 2010 | Journal of Thermal Analy sis and Calorimetry2010，99，2： | 1 |
| 3 | 显示文摘 | GHANEM R BELLO M A CALLEJON M | 1996 | J Pharm Biomed Anal1996，15，3： | 1 |
| 4 | Electrochemi- cal syntheses of highly ordered macroporous conducting po- lymers using self-assembled colloidal templates 显示文摘 | Bartlett P N Birkin P R Ghanem M A | 2001 | Chem2001，11，： | 1 |
| 5 | Complex vertebral malformation in Holstein cows in Japan and its inheritance to crossbred F1 generation显示文摘 | Ghanem ME Akita M Suzuki T | 2008 | Anim Reprod Sci2008，103，： | 1 |
| 6 | 查看详情显示文摘 | Naulin C Costes M Moudden Z Ghanem N Dorthe G | | 0，，： | 1 |
| 7 | MRI and discography in traumatic intervertebral disc lesions显示文摘 | Ghanem N Uhl M Muller C | 2006 | Eur Radiol2006，16，11： | 1 |
| 8 | Stochastic finite-element analysis of seismic soil-structure interaction 显示文摘 | Ghiocel D M Ghanem R G | 2002 | Journal of Engineer- ing Mechanics2002，128，1： | 1 |
| 9 | Gas permeation parameters and other physieochemical proper- ties of a polymer of intrinsic microporosity: Polybenzodioxane PIM-1显示文摘 | BUDD P M MCKEOWNB N B GHANEM B S | 2008 | J Membr Sci2008，325，2： | 1 |
| 10 | Defi-ciency of uridine monophosphate synthase(DUMPS)and X-chromosome deletion in fetal mummification in cattle显示文摘 | GHANEM M E NAKAO T NISHIBORI M | 2006 | Anim Reprod Sci2006，91，： | 1 |
| 11 | Neospora eaninum and com- plex vertebral malformation as possible causes of bovine fetal mum- mification 显示文摘 | Ghanem ME Suzuki T Akita M | 2009 | Can Vet J2009，50，4： | 1 |
| 12 | Bioequivalence assessment of azomycin (Julphar, UAE) as compared to zithromax ( Pfizer, USA) -two brands of azithromycin in healthy human volunteers 显示文摘 | NAJIB N M IDKAIDEK N GHANEM I E | 2001 | Biopharm Drug Dispos2001，22，1： | 1 |
| 13 | A Grid Infra- structure for Mixed Bioinformatics Data and Text Mining显示文摘 | GHANEM M CHORTARAS A GUO Y | 2005 | Computer Systems and Applications2005，34，1： | 1 |
| 14 | Factor XI mutation in a Holstein cow with repeat breeding in Japan 显示文摘 | Ghanem ME Nishibori M Nakao T | 2005 | Vet Med Sci2005，67，7： | 1 |
| 15 | Clomiphene citrate co-treatment with low dose urinary FSH versus urinary FSH for clomiphene resistant PCOS : randomized controlled trial 显示文摘 | Ghanem ME Elboghdady LA Hassan M | 2013 | J Assist Reprod Genet2013，30，11： | 1 |
| 16 | Microporous polymeric materials显示文摘 | Budd P M Makhseed S M Ghanem B S | 2004 | Mater Today2004，139，： | 1 |
| 17 | Factor XI muta- tion in a Hostein cow with repeat breeding in Japan 显示文摘 | GHANEM M E NISHIBORI M NAKAO T | 2005 | Vet Med Sci2005，67，7： | 1 |
| 18 | Polymorphism of MHC class Ⅲ genes : definition of restriction fragment linkagegroups and evidence for frequent deletions and duplications 显示文摘 | Ghanem N Uring-Lambert B Abbal M | 1988 | Hum Genet1988，79，3： | 1 |
| 19 | The value of penile duplex in the prediction of intracavernous drug-induced priapism显示文摘 | Shamloul R Ghanem H M Salem A | 2004 | Int J Impot Res2004，16，： | 1 |
| 20 | Egyptian artichoke volatile compounds protect against lead-induced hepatic and renal toxicity in male rats显示文摘 | Ghanem K Z Ramadan M M Farrag A R H | | 0，，02： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员