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| 1 | Targeting Tumor-Associated Macrophages by Anti-tumor Chinese Materia Medica显示文摘Tumor-associated macrophages(TAMs) play a key role in all stages of tumorigenesis and tumor progression. TAMs secrete different kinds of cytokines, chemokines, and enzymes to affect the progression, metastasis, and resistance to therapy depending on their state of reprogramming. Therapeutic benefit in targeting TAMs suggests that macrophages are attractive targets for cancer treatment. Chinese materia medica(CMM) is an important approach for treating cancer in China and in the Asian region. According to the theory of Chinese medicine(CM) and its practice, some prescriptions of CM regulate the body's internal environment possibly including the remodeling the tumor microenvironment(TME). Here we briefly summarize the pivotal effects of TAMs in shaping the TME and promoting tumorigenesis, invasion, metastasisand immunosuppression. Furthermore, we illustrate the effects and mechanisms of CMM targeting TAMs in antitumor therapy. Finally, we reveal the CMM's dual-regulatory and multi-targeting functions on regulating TAMs, and hopefully, provide the theoretical basis for CMM clinical practice related to cancer therapy. | PU Wei-ling SUN Li-kang GAO Xiu-mei Curzio Rüegg Muriel Cuendet Micheal O.Hottiger ZHOU Kun MIAO Lin ZHANG Yun-sha Margaret Gebauer | 2017 | Chinese Journal of Integrative Medicine2017，23，10： | 3 |
| 2 | Service devel- opment in traditional product manufacturing companies 显示文摘 | GEBAUER H KREMPL R FLEISCH E | 2008 | European Journal of Innovation Management2008，11，2： | 1 |
| 3 | Neurons and T cells:understanding this interaction for inflammatory neurological diseases显示文摘 | Yshii L Gebauer C Bernard Valnet R | 2015 | Eur J Immunol2015，45，10： | 1 |
| 4 | Interspecific competition and resource pulse utilization in a cold desert community显示文摘 | Gebauer R L E Schwinning S Ehleringer J R | 2002 | Ecology2002，83，9： | 1 |
| 5 | Three pheromone- binding proteins in olfactory sensilla of the two silkmoth species Antheraea polyphemus and Antheraea pernyi显示文摘 | Maida R Krieger J Gebauer T | 2000 | Eur J Biochem2000，267，： | 1 |
| 6 | assemblages in secondary tropical Loss of functional diversity of ant forests 显示文摘 | Bihn J H Gebauer G Brandl R | 2010 | Ecology2010，91，3： | 1 |
| 7 | Late infectious complications after high-dose therapy and autologous blood stem cell transplantation显示文摘 | Gruneisl R Gebauer W | 2002 | Med Klin(Munich)2002，97，11： | 1 |
| 8 | Multiple zircon growth and recrystallization during polyphase Late Carboniferous to Triassic metamorphism in granulites of the lw'ea Zonc ( Southern Alps ) : An ion microprobe ( SHRIMP ) study显示文摘 | Vavra G Gebauer D Schmid R | 1996 | Contributions to Mineralogy and Petrology1996，122，： | 1 |
| 9 | Internal morphology, habit and U-Th-Pb microanalysis of amphibolite-to-granulite facies zircons:geochro- nology of the Ivrea Zone (Southern Alps) 显示文摘 | Vavra G Sehmid R Gebauer D | 1999 | Contributions to Mineralogy and Petrology1999，134，： | 1 |
| 10 | Results of regional chemotherapy using the aortic stop-flow technique in advanced pancreatic carcinoma显示文摘 | Meyer F Gebauer T Grote R | 2006 | Surg Today2006，36，： | 1 |
| 11 | Dating of eclogite-facies zircons:the age of Alpine metamorphism in the Sesia-Lanzo Zone(Western Alps) 显示文摘 | Rubatto D Gebauer G Compagnoni R | 1999 | Earth Planet Sci Lett1999，167，： | 1 |
| 12 | Allometric relations and growth in pinus taeda:the effect of elevated CO2 and changing N availity显示文摘 | Gebauer R L E Reynolds J F Strain B R | 1996 | New Phytol1996，134，： | 1 |
| 13 | Multiple zircon growth and recrystallization during polyphase Late Carboniferous to Triassic metamorphism in granulites of the Ivrea Zone (Southern Alps):an ion microprobe (SHRIMP) study 显示文摘 | Vavra G Gebauer D Schmid R | 1996 | Contribution to Mineralogy and Petrology1996，122，： | 1 |
| 14 | Breakthrough performance of high-capacity membrane adsorbers in protein chromatography显示文摘 | Gebauer K H Thommes J Kula M R | 1996 | Chem Eng Sci1996，52，： | 1 |
| 15 | Feeling torn when everything seems right:Semantic incongruence causes felt ambivalence显示文摘 | Gebauer J E Maio G R and Pakizeh A | 2013 | Personality and Social Psychology Bulletin2013，39，6： | 1 |
| 16 | Multiple Zircon Growth and Recrystallization During Polyphase Late Carboniferous to Triassic Metamorphism in Granulites of the Ivrea Zone (Southern Alps):Anion Microprobe(SHRIMP)Study显示文摘 | Gebauer D Schmid R | 1996 | Contrib Mineral Petrol1996，122，： | 1 |
| 17 | Interspecific com- petition and resource pulse utilization in a cold desert community 显示文摘 | Gebauer R L E Schwinning S Ehleringer J R | 2003 | Ecology2003，83，： | 1 |
| 18 | Imiquimod 5% cream in the treatment of superficial basal cell carcinoma:results of a multicenter 6-week dose-response trial显示文摘 | Marks R Gebauer K Shumack S | 2001 | J Am Acad Dennatol2001，44，： | 1 |
| 19 | Multiple zircon growth and recrystallization during polyphase Late Carboniferous to Triassic metamorphism in granulites of the Ivrea Zone (Southern Alps):An ion microprobe (SHRIMP) study显示文摘 | Vavra G Gebauer D Schmid R | | 0，，： | 1 |
| 20 | Internal morphology,habit and U-Th-Pb microanalysis of amphibole to granulite facies zircon:Geochronology of the Ivrea Zone (Southern Alps)显示文摘 | Vavra G Schmid R Gebauer D | | 0，，： | 1 |
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