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1Effect of extracorporeal bioartificial liver support system on fulminant hepatic failure rabbits显示文摘AIM To evaluate the possibility of usingcultured human hepatocytes as a bridge betweenbioartificial liver and liver transplantation.METHODS In this experiment,the efficacy ofextracorporeal bioartificial liver support system(EBLSS)consisting of spheriodal human livercells and cultured hepatocytes supernatant wasassessed in vivo using galactosamine inducedrabbit model of fulminant hepatic failure.RESULTS There was no difference of survivalbetween the two groups of rabbits,but in thesupported rabbits serum alanineaminotransferase,total bilirubin and creatininewere significantly lower and hepatocyte necrosiswas markedly milder than those in controlanimals.In addition,a good viability of humanliver cells was noted after the experiment.CONCLUSION EBLSS plays a biologic role inmaintaining and compensating the function ofthe liver.Wang YJ Li MD Wang YM Chen GZ Lu GD Tan ZX 2000World Journal of Gastroenterology2000,6,2:17
2Orthotopic liver transplantation for fulminant hepatitis B显示文摘INTRODUCTION When fulminant hepatitis progress to deep encephalopathy,with stage Ⅲ or Ⅳ coma,it is commonly irreversible with a high mortality rate(80%-100%).Liver transplantation may beHe XS Huang JF Chen GH Fu Q Zhu XF Lu MQ Wang GD Guan XD 2000World Journal of Gastroenterology2000,6,3:14
3二倍体型及三倍体型卫氏并殖吸虫的DNA重复顺序的比较研究显示文摘从东北地区获得两类型卫氏并殖吸虫,提取其基因组DNA。用5种限制性内切酶消化,琼脂糖凝胶电泳后,观察两类型成虫基因组DNA的酶切片段。又用Southern印渍技术对两类型7种酶消化物的结果做了比较。显示两类型Bam HI、Hind Ⅲ及Eco RI的酶切结果基本相同,但Pst Ⅰ、DdeⅠ、HaeⅢ及HpaⅡ的结果却显示两类型的DNA重复顺序有明显差别。此结果在单个虫体DNA的杂交技术检测中也得到证实。王恩荣 郑韧坚 Cain GD 1991中国寄生虫学与寄生虫病杂志1991,9,1:11
4Tectonic framework of China and its relation with mineral resources——Cognition from geophysical data显示文摘TECTONIC and its evolution are theoretical basis of geology and summation in geosciences from investigation of the earth’s structure, composition, motion and history. Therefore, they are of great importance to the industrial activities. Various geological maps have been compiled in different scales after long-time observation of rock outcrops in mountains and torrents. These tectonic maps, which are obtained based upon the cognition and judgment of tectonic movements in different ages, are summarization regarding the regularity of geological phenomenon in terms of theory, and provide service of exploration and references for environmental protection and prevention and control of disaster.Liu, GD Hao, TY Liu, Y 1997Chinese Science Bulletin1997,42,2:5
5强效血小板P2Y12受体抑制剂治疗老年与非老年急性冠状动脉综合征的有效性和安全性显示文摘本文研究的目的是探讨与以往治疗急性冠脉综合征(ACS)的一线药物clopidogrel相比,强效血小板P2Y12受体抑制剂prasugrel和ticagrelor治疗老年和非老年ACS的有效性和安全性。对象与方法:①有效性分析。受试者为老年患者7387例,其中3657例接受强效P2Y12受体抑制剂治疗,3730例接受clopidogrel治疗;非老年患者36175例.张四维 Tarantini G Ueshima D Amico GD 2018国际老年医学杂志2018,39,2:4
6Iunochemical evidence that cholesteryl ester transfer protein and bactericidal/permeability-increasing protein share a similar tertiary structure 显示文摘Valérie GD Viken T Vinita CH 1999Protein Science1999,8,:3
7Primary pancreatic anaplastic large cell lymphoma, ALK negative: A case report显示文摘We present the fourth case of a primary pancreatic anaplastic large cell lymphoma (ALCL), ALK-. An 80-year-old man was admitted to our clinic for further investigation of a fever of unknown origin. He noted anorexia, weight loss and fatigue. His laboratory tests showed anemia and a great elevation of ESR, LDH, and β2 microglobulin. In CT and MRI scan, a soft tissue mass in the pancreas was observed. A repeated endoscopy after his admission revealed an ulcerated mass-like deformity of the duodenal bulb. Explorative laparotomy confirmed a diffuse spread of an unresectable malignant pancreatic mass extending to the adjacent organs. Duodenal and surgical biopsies identified an ALCL of T-cell lineage, ALK-. The patient died in the Intensive Care Unit due to hemodynamic instability.Our case is the first one indicating that primary pancreatic lymphoma should be suspected in a patient with pancreatic mass and elevated serum LDH and β2 microglobulin.Christos G Savopoulos NE Tsesmeli GD Kaiafa AT Zantidis MT Bobos AI Hatzitolios ST Papavramidis IS Kostopoulos 2005World Journal of Gastroenterology2005,11,39:3
8Phase Ⅲ randomized,intergroup trial assessing imatinib mesylate at two dose levels in patients with unresectable or metastatic gastrointestinal stromal tumors expressing the kit receptor tyrosine kinase:S0033显示文摘Blanke CD Rankin C Demetri GD 0,,04:3
9Long-term results from a randomized phase Ⅱ trial of standard-versus higher-dose imatinib mesylate for patients with unresectable or metastatic gastrointestinal stromal tumors expressing KIT显示文摘Blanke CD Demetri GD yon Mehren M 0,,04:3
10电沉积Ag/Sn偶界面反应及其动力学显示文摘采用扫描电子显微镜(SEM)、电子能谱仪(EDS)、X射线衍射仪(XRD)对室温时效及125-225℃热处理的电沉积Ag/Sn偶反应区结构及相组成进行分析,研究Ag/Sn界面固相反应的动力学过程。研究表明:在刚电沉积的Ag/Sn偶中发生Ag/Sn界面固相反应,形成Ag3Sn;在室温时效过程中Ag3Sn层生长缓慢,但随着热处理温度的提高(125~200℃),Ag3Sn层生长速率显著提高;Ag/Sn界面固相反应为-扩散控制的反应过程,反应的激活能为70.0kJ/mol。汤文明 HE An-qiang LIU Qi IVEY GD 2009中国有色金属学报2009,19,5:3
11固氮酶铁钼辅基理化特性的研究显示文摘在紫外可见光谱区内,固氮酶铁钼辅基〔(Mo_2Fe_(12)S_(12))4-〕均无特征吸收峰,不含高柠檬酸盐。含双钼的铁硫簇〔(Mo_2Fe_(6~12)S_(6~12))^(1~4)-〕的电荷数、颜色与该金属簇中的亚铁量成对应关系,并都有较高的生物重组活性.黄河清 Watt,GD 1995生物化学杂志1995,11,4:3
12Prevention of spinal cord ischaemia during descending thoracic and thoracoabdominal aortic surgery显示文摘Wan IY Angelini GD Bryan AJ Ryder I Underwood MJ 2001Eur J Cardiothorac Surg2001,19,2:2
13Use of polymerase chain reaction and rabbit infectivity testing to detect Treponema pallidum in amniotic fluid显示文摘Grimprel E Sanchez PJ Wendel GD 1991J Clin Microbiol1991,29,:2
14NIDDM as a disease of the innate immune system association of acute-phase reactants and interleukin-6 with metabolic syndrome-X显示文摘Dickup JC Mattock MB Chusney GD 1997Diabetologia1997,40,11:2
15Preliminary studies on the ionic pulse of snowmelt runoff in the Urumqi River, Xinjiang, Northwest China显示文摘IONIC pulse of snowmelt and its runoff in seasonally snow-covered alpine catchments was de-fined by Johannessen et al. When a snowpack begins melting, the first meltwater drainingthrough the pack carries a large fraction of the soluble ions with it, an ionic pulse. 10% of thefirst meltwater may drain 80% of the soluble contents out of the snowpack within severalhours or days. In other words, an ionic pulse designates a peak in ionic concentration duringthe initial melting process of a snowpack. The peak has been proved by a plot test 10 timesLiu, FJ Williams, M Cheng, GD Yang, DQ 1997Chinese Science Bulletin1997,42,19:2
16Bcl-2 and bak may play a pivotal role in sodium butyrate-induced apoptosis in colonic epithelial cells;however overexpression of bcl-2 does not protect against bak-mediated apoptosis 显示文摘Hague A Diaz GD Hicks DJ 1997Int J Cancer1997,72,5:2
17Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors显示文摘Demetri GD von Mehren M Blanke CD 0,,:2
18阿利吉仑对2型糖尿病合并高血压患者循环内皮祖细胞和血管功能的影响显示文摘该研究旨在探讨阿利吉仑对2型糖尿病合并高血压患者循环内皮祖细胞(endothelial progenitor cells,EPC)和血管功能的影响。方法:研究纳入血糖控制稳定、首次诊断为轻度原发性高血压〉50岁的2型糖尿病患者。在A阶段(n=20),患者接受150-300mg/d阿利吉仑治疗3月。Raptis AE Markakis KP Mazioti MC Ikonomidis I Maratou EP Vlahakos DV Kotsifaki EE Voumvourakis AN Tsiro- gianni AG Lambadiari VA Lekakis JP Raptis SA Dimitria- dis GD 练桂丽 叶鹏 2015中华高血压杂志2015,23,7:2
19Mechanisms of acetaldehyde mediated growth inhibition: delayed cell cycle progression and induction of apoptosis显示文摘Zimmerman BT Crawford GD Dahl R 1995Alcohol-clin-exp-res1995,19,2:2
20Simultaneous determination of phenytoin,carbamazepine, and 10, 11 -carbamazepine epoxide in human plasma by high-performance liquid chromatography with ultraviolet detection显示文摘Bhatti MM Hanson GD Schultz L 1998J Pharm Biomed Anal1998,16,:2
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