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| 1 | Hydrophobic protein in colorectal cancer in relation to tumor stages and grades显示文摘AIM: To identify differentially expressed hydrophobic proteins in colorectal cancer. METHODS: Eighteen pairs of colorectal cancerous tissues in addition to tissues from normal mucosa were analysed. Hydrophobic proteins were extracted from the tissues, separated using 2-D gel electrophoresis and analysed using Liquid Chromatography Tandem Mass Spectrometry (LC/MS/MS). Statistical analysis of the proteins was carried out in order to determine the significance of each protein to colorectal cancer (CRC) and also their relation to CRC stages, grades and patients’ gender. RESULTS: Thirteen differentially expressed proteins which were expressed abundantly in either cancerous or normal tissues were identified. A number of these proteins were found to relate strongly with a particular stage or grade of CRC. In addition, the association of these proteins with patient gender also appeared to be significant.CONCLUSION: Stomatin-like protein 2 was found to be a promising biomarker for CRC, especially in female patients. The differentially expressed proteins identified were associated with CRC and may act as drug target candidates. | Lay-Chin Yeoh Chee-Keat Loh Boon-Hui Gooi Manjit Singh Lay-Harn Gam | 2010 | World Journal of Gastroenterology2010，16，22： | 3 |
| 2 | Discrete-Time Chaotic Systems Synchronization Based on Vector Norms Approach显示文摘Suitable stabilization conditions obtained for continuous chaotic systems are generalized to discrete-time chaotic systems. The proposed approach, leading to these conditions for complete synchronization is based on the use of state feedback and aggregation techniques for stability studies associated with the arrow form matrix for system description. The results are successfully applied for two identical discrete-time hyper chaotic Henon maps with different orders and also for non-identical discrete-time chaotic systems with same order namely the Lozi and the Ushio maps. | GAM Rihab SAKLY Anis | 2017 | Journal of Systems Science & Complexity2017，30，5： | 2 |
| 3 | Serum uric acid in relation to age and physique in health and in coronary heart disease显示文摘 | Gertler MM Gam SM Levine SM | 1951 | Ann Intern Med1951，34，： | 1 |
| 4 | Laparoscopic pyeloplasty:comparison between retroperitoneoscop-ic and transperitoneal approach显示文摘 | Abuanz S Gamé X Roche J B | 2010 | Urology2010，76，4： | 1 |
| 5 | An nexin V for flow cytometric detection of phosphatidylserine ex pression on B cells undergoing apoptosis显示文摘 | Koopman G Reutelingsperger CPM Kuijten GAM | 1994 | Blood1994，8414，： | 1 |
| 6 | Photoconductivity:a probe of defect states in carbon in carbon aerogels 显示文摘 | REYNOLDS GAM WANG ZH DRESSELHAUS M S | 1994 | Phys Rev B1994，49，15： | 1 |
| 7 | Delayed administration of dexrazoxane provides cardioprotection for patients with advanced breast cancer treated with doxorubicin - containing therapy 显示文摘 | Swain SM Whaley FS Gerber MC Ewer MS Bianchine JR Gams RA | 1997 | J Clin Oncol1997，15，4： | 1 |
| 8 | Home-based health monitoring of the elderly through gait recognition显示文摘 | Bogdan Pogorelc MatjaGams | 2012 | Journal of Ambient Intelligence and Smart Environments2012，4，5： | 1 |
| 9 | Rapid and sensitive assay method for simultaneous quantification of urinary nicotine and cotinine using gas chromatography-mass spectrometry显示文摘 | MAN C N GAM L H ISMAIL S | 2006 | Journal of Chromatography B2006，844，： | 1 |
| 10 | Joint procurement and demand-side bidding strategies under price volatility显示文摘 | Nie X Boyac T Gam/is M | 2015 | Annals of Operations Research2015，，25： | 1 |
| 11 | Inhibition of HIV budding by a genetically selected cyclic peptide targeting the Gag-TSG101 interaction显示文摘 | Tavassoli A Lu Q Gam J | 2008 | ACS Chem Biol2008，3，12： | 1 |
| 12 | Serum uric acid in relation to age and physique in health and in coronary heart disease显示文摘 | Gam SM Levine SA | 1951 | Ann Intern Med1951，34，： | 1 |
| 13 | New method for the synthetic preparation of isoquinoline bases 显示文摘 | Pictet A Gams A | 1909 | Ber Dtsch Chem Ges1909，42，： | 1 |
| 14 | A 14-bit intrinsic accuracy C1 random walk CMOS DAC 显示文摘 | Plas GAM Vandenbussche J Sansen W | 1999 | IEEE Journal of Solid State Circuits1999，34，12： | 1 |
| 15 | Context-based ensemble method for man energy expenditure estimation显示文摘 | Hristijan Gjoreski Bostjan Kaluza Matjaz Gams Radoje Milic Mitja Lustrek | 2015 | Applied Soft Computing2015，13，： | 1 |
| 16 | Annexin-V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis 显示文摘 | Koopman G Reutelingsperger CPM Kuihten GAM | 1994 | Blood1994，84，5： | 1 |
| 17 | Significance of the subvalvular apparatus for left ventricular dimensions and systolic function:experimental replacement of the mitralvalve显示文摘 | GAMS E HAGL S SCHAD H | 1991 | Thorac Cardiovas Surg1991，39，1： | 1 |
| 18 | Effects of short chain fatty acids on growth and differentiation of the human colon cancer cell line HT29显示文摘 | Gam Daviaud D Denis-Pouxviel C | | 0，，： | 1 |
| 19 | Chemometrics of differentially expressed proteins from colorectal cancer patients显示文摘AIM:To evaluate the usefulness of differentially expressed proteins from colorectal cancer (CRC) tissues for differentiating cancer and normal tissues.METHODS:A Proteomic approach was used to identify the differentially expressed proteins between CRC and normal tissues.The proteins were extracted using Tris buffer and thiourea lysis buffer (TLB) for extraction of aqueous soluble and membrane-associated proteins,respectively.Chemometrics,namely principal component analysis (PCA) and linear discriminant analysis (LDA),were used to assess the usefulness of these proteins for identifying the cancerous state of tissues.RESULTS:Differentially expressed proteins identified were 37 aqueous soluble proteins in Tris extracts and 24 membrane-associated proteins in TLB extracts.Based on the protein spots intensity on 2D-gel images,PCA by applying an eigenvalue > 1 was successfully used to reduce the number of principal components (PCs) into 12 and seven PCs for Tris and TLB extracts,respectively,and subsequently six PCs,respectively from both the extracts were used for LDA.The LDA classification for Tris extract showed 82.7% of original samples were correctly classified,whereas 82.7% were correctly classified for the cross-validated samples.The LDA for TLB extract showed that 78.8% of original samples and 71.2% of the cross-validated samples were correctly classified.CONCLUSION:The classification of CRC tissues by PCA and LDA provided a promising distinction between normal and cancer types.These methods can possibly be used for identification of potential biomarkers among the differentially expressed proteins identified. | Lay-Chin Yeoh Saravanan Dharmaraj Boon-Hui Gooi Manjit Singh Lay-Harn Gam | 2011 | World Journal of Gastroenterology2011，17，16： | 1 |
| 20 | What exactly is Trichoderma harzinum?显示文摘 | Meyer W | 1998 | Mycologia1998，90，5： | 1 |
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