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| 1 | LINEAR SEARCH FOR A BROWNIAN TARGET MOTION显示文摘A target is assumed to move according to a Brownian motion on the real line.The searcher starts from the origin and moves in the two directions from the starting point.The object is to detect the target.The purpose of this paper is to find the conditions under which the expected value of the first meeting time of the searcher and the target is finite,and to show the existence of a search plan which made this expected value minimum. | A.B.El-Rayes AbdEl-MoneimA.Mohamed Hamdy M.Abou Gabal | 2003 | Acta Mathematica Scientia2003，23，3： | 3 |
| 2 | Low-density lipoprotein receptor genetic polymorphism in chronic hepatitis C virus Egyptian patients affects treatment response显示文摘AIM: To correlate a genetic polymorphism of the low-density lipoprotein(LDL) receptor with antiviral responses in Egyptian chronic hepatitis C virus(HCV) patients.METHODS: Our study included 657 HCV-infected patients with genotype 4 who received interferonbased combination therapy. Patients were divided into two groups based on their response to therapy: 356 were responders, and 301 were non-responders. Patients were compared to 160 healthy controls. All patients and controls underwent a thorough physical examination, measurement of body mass index(BMI) and the following laboratory tests: serum alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, albumin, total bilirubin, direct bilirubin, prothrombin time, prothrombin concentration, INR, complete blood count, serum creatinine, fasting blood sugar, HCV antibody, and hepatitis B surface antigen. All HCV patients were further subjected to the following laboratory tests: HCV-RNA using quantitative polymerase chain reaction(PCR), antinuclear antibodies, thyroid-stimulating hormone, an LDL receptor(LDLR) genotype study of LDLR exon8 c.1171G>A and exon-10 c.1413G>A using real-time PCR-based assays, abdominal ultrasonography, ultrasonographic-guided liver biopsy, and histopathological examination of liver biopsies. Correlations of LDL receptor polymorphisms with HAI, METAVIR score, presence of steatosis, and BMI were performed in all cases.RESULTS: There were no statistically significant differences in response rates between the different types of interferon used or LDLR exon10 c.1413G>A. However, there was a significant difference in the frequency of the LDL receptor exon8 c.1171G>A genotype between cases(AA: 25.9%, GA: 22.2%, GG: 51.9%) and controls(AA: 3.8%, GA: 53.1% and GG: 43.1%)(P < 0.001). There was a statistically significant difference in the frequency of the LDLR exon 8C:1171 G>A polymorphism between responders(AA: 3.6%, GA: 15.2%, GG: 81.2%) and nonresponders(AA: 52.2%, GA: 30.6%, GG: 17.2%)(P < 0.001). The G allele of LDL receptor exon8 c.1171G>A predominated in cases and controls over the A allele, and a statistically significant association with response to interferon was observed. The frequency of the LDLR exon8 c.1171G>A allele in non-responders was: A: 67.4% and G: 32.6 vs A: 11.2% and G: 88.8% in responders(P < 0.001). Therefore, carriers of the A allele exhibited a 16.4 times greater risk for nonresponse. There was a significant association between LDL receptors exon8 c.1171G>A and HAI(P < 0.011). There was a significant association between LDL receptors exon8 c.1171G>A and BMI. The mean BMI level was highest in patients carrying the AA genotype(28.7 ± 4.7 kg/m2) followed by the GA genotype(28.1 ± 4.8 kg/m2). The lowest BMI was the GG genotype(26.6 ± 4.3 kg/m2)(P < 0.001). The only significant associations were found between LDL receptors exon8 c.1171G>A and METAVIR score or steatosis(P < 0.001).CONCLUSION: LDL receptor gene polymorphisms play a role in the treatment response of HCV and the modulation of disease progression in Egyptiansinfected with chronic HCV. | Mazen Naga Mona Amin Dina Algendy Ahmed Elbadry May Fawzi Ayman Foda Serag Esmat Dina Sabry Laila Rashed Samia Gabal Manal Kamal | 2015 | World Journal of Gastroenterology2015，21，39： | 2 |
| 3 | Nonisothermal Decomposition of CdC2O4-FeC2 O4 Mixtures in Air 显示文摘 | Diefallah E H M Gabal M A Bellihi E A A | 2001 | Thermochimica Acta2001，376，： | 1 |
| 4 | Kinetics of the Thermal Decomposition of CuC2O4-ZnC2 O4 Mixture in Air显示文摘 | Gabal M A | 2003 | Thermochimica Acta2003，402，： | 1 |
| 5 | Isolation and mapping of microsatellite markers specific for the D genome of bread wheat显示文摘 | Pestsova E Gabal M W R6der M S | 2000 | Genome2000，43，4： | 1 |
| 6 | Secretory carcinoma of male breast:case report and review of the literature显示文摘 | Gabal S Talaat S | 2011 | Int J Breast Cancer2011，2011，70： | 1 |
| 7 | Effect of Calcination Temperature on Co (Ⅱ) Oxalate Dihydrate-Iron (Ⅱ) Oxalate Dihydrate Mixture:DTA-TG,XRD,M(o)ssbauer,FT-IR and SEM Studies (Part Ⅱ)显示文摘 | Gabal M A EI-Bellihi A A Ata-Allah S S | 2003 | Materials Chemistry and Physics2003，81，1： | 1 |
| 8 | The intelligent design of high strength,creep-resistance aluminum alloys 显示文摘 | Zhu A W Gabal B M Shiflet G J | 2002 | Materials Science Forum2002，，： | 1 |
| 9 | Safety of perioperative aspirin therapy in pancreatic operations显示文摘 | Wolf AM Pucci M J Gabale SD | 2014 | Surgery2014，155，1： | 1 |
| 10 | Kinetics of the thermal decomposition of CuC2O4-ZnC2O4 mixture in air 显示文摘 | Gabal M A | 2003 | Thermochimica Acta2003，402，12： | 1 |
| 11 | The role of urinary polassium in the pathogenesis and diagnosis显示文摘 | Parsons CL Greenberger M Gabal L | 1998 | J Urol1998，159，： | 1 |
| 12 | Secretory carcinoma of male breast: case report and review of the literature 显示文摘 | Gabal S Talaat S | 2011 | Int J Breast Cancer2011，2011，70： | 1 |
| 13 | Kinetics of the Thermal Decomposition of CuC2O4-ZnC2O4 Mixture in Air显示文摘 | Gabal M A | 2003 | Thermochimica Acta2003，402，： | 1 |
| 14 | Non-Isothermal Studies for the Decomposition Course of CdC2O4-ZnC2O4 Mixture in Air显示文摘 | Gabal M A | 2004 | Thermochimica Acta2004，412，12： | 1 |
| 15 | Secretory carcinoma of male breast: case report and review of the literature 显示文摘 | GABAL S TALAAT S | 2011 | Int J Breast Cancer2011，2011，70： | 1 |
| 16 | Kinetics of the thermal decomposition of CuC2O4·ZnC2O4 mixture in air显示文摘 | Gabal M A | 2003 | Thermochim Acta2003，402，12： | 1 |
| 17 | Concerning the Cation Distribution in MnFe2O4 Synthesized through the Thermal Decomposition of Oxalates显示文摘 | Gabal M A Ata-Allah S S | 2004 | J Phys Chem Solids2004，65，： | 1 |
| 18 | Secretory carcinoma of male breast: case report and review of the literature 显示文摘 | Gabal S Talaat S | 2011 | Int J Breast Cancer2011，，70： | 1 |
| 19 | Effect of aflatoxin-contaminated feed on morbidity and residues in walleye fish显示文摘 | Hussain M Gabal M A Wilton T | 1993 | Vet Hum Toxicol1993，35，： | 1 |
| 20 | Minimally invasive bioabsorbable bone plates for rigid internal fixation of mandible fractures显示文摘 | Gaball C Lovald S Baack B | 2011 | Arch Facial Plast Surg2011，13，1： | 1 |
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