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| 1 | Annual cost of illness of stomach and esophageal cancer patientsin urban and rural areas in China: A multi-center study显示文摘Objective: Stomach and esophageal cancer are imposing huge threats to the health of Chinese people whereas there were few studies on the financial burden of the two cancers.Methods: Costs per hospitalization of all patients with stomach or esophageal cancer discharged between September 2015 and August 2016 in seven cities/counties in China were collected, together with their demographic information and clinical details. Former patients in the same hospitals were sampled to collect information on annual direct non-medical cost, indirect costs and annual number of hospitalization. Annual direct medical cost was obtained by multiplying cost per hospitalization by annual number of hospitalization. Annual cost of illness(ACI)was obtained by adding the average value of annual direct medical cost, direct non-medical cost and indirect cost,stratified by sex, age, clinical stage, therapy and pathologic type in urban and rural areas. Costs per hospitalization were itemized into eight parts to calculate the proportion of each part. All costs were converted to 2016 US dollars(1 USD=6.6423 RMB).Results: Totally 19,986 cases were included, predominately male. Mean ages of stomach cancer and urban patients were lower than that of esophageal cancer and rural patients. ACI of stomach and esophageal cancer patients were $10,449 and $13,029 in urban areas, and $2,927 and $3,504 in rural areas, respectively. Greater ACI was associated with male, non-elderly patients as well as those who were in stage I and underwent surgeries.Western medicine fee took the largest proportion of cost per hospitalization.Conclusions: The ACI of stomach and esophageal cancer was tremendous and varied substantially among the population in China. Preferential policies of medical insurance should be designed to tackle with this burden and further reduce the health care inequalities. | Zhixun Yang Hongmei Zeng Ruyi Xia Qian Liu Kexin Sun Rongshou Zheng Siwei Zhang Changfa Xia He Li Shuzheng Liu Zhiyi Zhang Yuqin Liu Guizhou Guo Guohui Song Yigong Zhu Xianghong Wu Bingbing Song Xianzhen Liao Yanfang Chen Wenqiang Wei Guihua Zhuang Wanqing Chen | 2018 | Chinese Journal of Cancer Research2018，30，4： | 22 |
| 2 | Colorectal cancer burden and trends:Comparison between China and major burden countries in the world显示文摘Objective:To summarize the colorectal cancer(CRC)burden and trend in the world,and compare the difference of CRC burden between other countries and China.Methods:Incidence and mortality data were extracted from the GLOBOCAN2018 and Cancer Incidence in Five Continents.Age-specific incidence trend was conducted by Joinpoint analysis and average annual percent changes were calculated.Results:About 1.85 million new cases and 0.88 million deaths were expected in 2018 worldwide,including 0.52 million(28.20%)new cases and 0.25 million(28.11%)deaths in China.Hungary had the highest age-standardized incidence and mortality rates in the world,while for China,the incidence and mortality rates were only half of that.CRC incidence and mortality were highly correlated with human development index(HDI).Unlike the rapid increase in Republic of Korea and the downward trend in Canada and Australia,the age-standardized incidence rates by world standard population in China and Norway were rising gradually.The age-specific incidence rate in the age group of 50-59 years in China was increasing rapidly,while in Republic of Korea and Canada,the fastest growing age group was 30-39 years.Conclusions:The variations of CRC burden reflect the difference of risk factors,as well as levels of HDI and screening(early detection activities).The burden of CRC in China is high,and the incidence of CRC continues to increase,which may lead to a sustained increase in the burden of CRC in China in the future.Screening should be expanded to control CRC,and focused on young people in China. | Jiachen Zhou Rongshou Zheng Siwei Zhang Hongmei Zeng Shaoming Wang Ru Chen Kexin Sun Minjuan Li Jianhua Gu Guihua Zhuang Wenqiang Wei | 2021 | Chinese Journal of Cancer Research2021，33，1： | 16 |
| 3 | An integrated quantum secure communication system显示文摘In this paper, we investigate experimentally an integrated quantum secure communication system using weak coherent state. Two modules are involved in the presented system. One is used for generating the secret key which is obtained using continuous variable quantum key distribution scheme, and the other serves to encrypt and decrypt the real-time private data using a pure quantum cryptographic algorithm. The sifted key rate with reverse reconciliation is 8.6 and 3.9 kb/s in the quantum key distribution scheme under the individual attack and the collective attack, respectively. The system uses an all-fiber dual unbalance beam Mach-Zehnder interferometer, and is implemented with a 500 kb/s modulation rate over 27.2 km of optical fiber. | DAI WenChao LU Yuan ZHU Jun ZENG GuiHua | 2011 | Science China(Information Sciences)2011，54，12： | 11 |
| 4 | Evaluating efficacy of screening for upper gastrointestinal cancer in China:a study protocol for a randomized controlled trial显示文摘Objective: To evaluate the efficacy and feasibility of screening procedure for upper gastrointestinal cancer in both high-risk and non-high-risk areas in China.Setting: Seven cities/counties, representing three economical-geographical regions(Eastern, Central and Western) in China, were selected as screening centers: three in high-risk areas and four in non-high-risk areas.Participants: Villages/communities in these seven centers regarded as clusters were randomly assigned to either intervention group(screening by endoscopic examination) or control group(with normal community care) in a 1:1ratio stratified by each center. Eligible participants are local residents aged 40–69 years in the selected villages/communities with no history of cancer or endoscopic examination in the latest 3 years who are mentally and physically competent. Those who are not willing to take endoscopic examination or are unwilling to sign the consent form are excluded from the study. Totally 140,000 participants will be enrolled.Interventions: In high-risk areas of upper gastrointestinal cancer, all subjects in screening group will be screened by endoscopy. In non-high-risk areas, 30% of the subjects in screening group, identified through a survey,will be screened by endoscopy.Primary and secondary outcome measures: The primary outcome is the mortality caused by upper gastrointestinal cancer. The secondary outcomes include detection rate, incidence rate, survival rate, and clinical stage distribution. Additional data on quality of life and cost-effectiveness will also be collected to answer important questions regarding screening effects.Conclusions: Screening strategy evaluated in those areas with positive findings may be promoted nationally and applied to the majority of Chinese people. On the other hand, negative findings will provide scientific evidence for abandoning a test and shifting resources elsewhere.Trial registration: The study has been registered with the Protocol Registration System in Chinese Clinical Trial Registry. | wanqing chen hongmei zeng ru chen ruyi xia zhixun yang changfa xia rongshou zheng wenqiang wei guihua zhuang xueqin yu jie he | 2017 | Chinese Journal of Cancer Research2017，29，4： | 11 |
| 5 | Effect of temperature on anoxic metabolism of nitrites to nitrous oxide by polyphosphate accumulating organisms显示文摘Temperature is an important physical factor, which strongly influences biomass and metabolic activity. In this study, the effects of temperature on the anoxic metabolism of nitrite(NO-2) to nitrous oxide(N2O) by polyphosphate accumulating organisms, and the process of the accumulation of N2O(during nitrite reduction), which acts as an electron acceptor, were investigated using 91% ± 4% Candidatus Accumulibacter phosphatis sludge. The results showed that N2O is accumulated when Accumulibacter first utilize nitrite instead of oxygen as the sole electron acceptor during the denitrifying phosphorus removal process. Properties such as nitrite reduction rate, phosphorus uptake rate, N2O reduction rate, and polyhydroxyalkanoate degradation rate were all influenced by temperature variation(over the range from 10 to 30°C reaching maximum values at 25°C). The reduction rate of N2O by N2O reductase was more sensitive to temperature when N2O was utilized as the sole electron acceptor instead of NO2, and the N2O reduction rates, ranging from 0.48 to 3.53 N2O-N/(hr·g VSS), increased to 1.45 to 8.60 mg N2O-N/(hr·g VSS). The kinetics processes for temperature variation of 10 to 30°C were(θ1 = 1.140–1.216 and θ2= 1.139–1.167). In the range of 10°C to 30°C, almost all of the anoxic stoichiometry was sensitive to temperature changes. In addition, a rise in N2O reduction activity leading to a decrease in N2O accumulation in long term operations at the optimal temperature(27°C calculated by the Arrhenius model). | Zhijia Miao Wei Zeng Shuying Wang Yongzhen Peng Guihua Cao Dongchen Weng Guisong Xue Qing Yang | 2014 | Journal of Environmental Sciences2014，26，2： | 7 |
| 6 | Downregulation of cyclooxygenase-1 is involved in gastric mucosal apoptosis via death signaling in portal hypertensive rats显示文摘门高血压(PHT ) gastropathy 是肝肝硬化的经常的复杂并发症,带之一从肝硬化死亡引起。Apoptosis 广泛地被认为从坏死的房间死亡是房间死亡和一个不同实体的一个活跃精力依赖者模式。胃的 mucosal apoptosis 是否涉及 PHT gastropathy,是不清楚的。通过 cyclooxygenase (艇长) 生产的前列腺素(PG ) 被认为从损害和 apoptosis 在胃肠的 mucosa 的保护起一个关键作用。然而,在 PHT gastropathy 的艇长的角色仍然不清楚地被理解。这研究的目的是调查(1 ) 胃的 mucosal apoptosis 是否涉及 PHT gastropathy,(2 ) 艇长的 downregulation 贡献这 apoptosis。在这研究,当 mucosal 增长在 PHT 老鼠被禁止时,我们证明胃的 mucosal apoptosis 显著地被增加。胃的 mucosal COX-1 显著地在 mRNA 和蛋白质层次被压制,并且 PGE2 在 PHT 老鼠被减少。进一步, PGE2 处理在 PHT 老鼠压制了胃的 mucosal apoptosis。然而,胃的 mucosal COX-2 层次没在假冒操作老鼠和 PHT 老鼠之间不同。肿瘤坏死因素的胃的 mucosal 层次 --(TNF-) 并且船边交货 ligand,然而并非 TNF 相关的导致 apoptosis ligand,被增加,并且激活的 caspase-8 和 caspase-3 层次是在 PHT 老鼠的 upregulated。到 cytosol 的从线粒体的细胞色素 c 的版本没在 PHT 老鼠被观察。我们的数据显示 COX-1 的 downregulation 经由死亡涉及胃的 mucosal apoptosis 调停信号的类型 -- 我在 PHT 老鼠的房间死亡。 | Bin Wu Lixian Zeng Ying Lin Zhuofu Wen Guihua Chen Ryuichi Iwakiri Kazuma Fujimoto | 2009 | Cell Research2009，19，11： | 6 |
| 7 | Hybrid quantum private communication with continuous-variable and discrete-variable signals显示文摘The quantum key distribution(QKD) has been entering the practical application era. Subsequently, hybrid quantum private communication with discrete-variable signals, continuous-variable signals, and classic optical signals becomes inevitable in the practical scenario. In this paper, we experimentally investigated the mutual effects between the discrete-variable QKD(DVQKD) and the continuous-variable QKD(CVQKD) via a fiber channel. The experimental results show that the DVQKD will be influenced by the continuous-variable quantum signals and classic optical signals, while the CVQKD is not sensitive to the discrete-variable quantum signals. | LIU WeiQi PENG JinYe WANG Chao CAO ZhengWen HUANG Duan LIN DaKai HUANG Peng ZENG GuiHua | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，2： | 4 |
| 8 | Enhanced NTRU cryptosystem eliminating decryption failures显示文摘An enhaned NTRU cryptosystem eliminating decryption failures is proposed without using padding schemes and can resist the oracle model andchosen-ciphertext attacks. Because lattice reduction is the main threat to lattice-based cryptosystems, lattice reductionalgorithms are analyzed to evaluate the security of this scheme. Furthermore, the new scheme remains the advantage of high efficiency of original NTRU. | Yao Jun Zeng Guihua | 2006 | Journal of Systems Engineering and Electronics2006，17，4： | 3 |
| 9 | Realization of error correction and reconciliation of continuous quantum key distribution in detail显示文摘The efficiency of reconciliation in the continuous key distribution is the main factor which limits the ratio of secret key distribution. However,the efficiency depends on the computational complexity of the algorithm. This paper optimizes the two main aspects of the reconciliation process of the continuous key distribution:the partition of interval and the estimation of bit. We use Gaussian approximation to effectively speed up the convergence of algorithm. We design the estimation function as the estimator of the SEC(sliced error correction) algorithm. Therefore,we lower the computational complexity and simplify the core problem of the reconciliation algorithm. Thus we increase the efficiency of the reconciliation process in the continuous key distribution and then the ratio of the secret key distribution is also increased. | QIAN XuDong HE GuangQiang ZENG GuiHua | 2009 | Science in China(Series F)2009，52，9： | 3 |
| 10 | A generalized reverse block Jacket transform显示文摘 | Zeng Guihua Lee M H | 2008 | IEEE Transactions on Circuits and Systems2008，55，6： | 1 |
| 11 | A new shape descriptor based on centroid-radii model and wavelet transform显示文摘 | Kong Xiaodong Luo Qingshan Zeng Guihua | 2007 | Optics Communications2007，273，2： | 1 |
| 12 | One-pot synthesis of 2,5-bis(hydroxymethyl)furan from biomass derived 5-(chloromethyl)furfural in high yield显示文摘5-(Chloromethyl)furfural(CMF),as a new platform molecular,has become a hot topic in the field of biorefinery.Herein,the one-pot conversion of CMF to 2,5-bis(hydroxymethyl)furan(BHMF)in the water phase was demonstrated for the first time.A 91%BHMF yield was obtained over Ru/Cu Oxcatalyst,and BHMF was mainly produced by the consecutive hydrolysis and hydrogenation of CMF with 5-hydroxymethylfurfural(HMF)as an intermediate.Kinetic studies revealed that the conversion of HMF to BHMF was the rate-determining step.Remarkably,the characterizations and density functional theory(DFT)calculations further revealed the lower electron density of Ru NPs in Ru/Cu Oxcatalyst,resulting in a larger adsorption energy and a smaller free energy difference for the formation of alcohols.The present findings offered a new pathway for biomass-derived diol production through CMF as a potential source. | Binglin Chen Yunchao Feng Sen Ma Weizhen Xie Guihua Yan Zheng Li Jonathan Sperry Shuliang Yang Xing Tang Yong Sun Lu Lin Xianhai Zeng | 2023 | Journal of Energy Chemistry2023，，1： | 1 |
| 13 | Microwave catalytic desulfurization and denitrification simultaneously on Fe/Ca-5A zeolite catalyst显示文摘 | Wei Zaishan Zeng Guihua Xie Zhirong | 2009 | Energy&Fuel2009，23，： | 1 |
| 14 | Message Authentication Scheme Based on Quantum Error-correction Codes显示文摘 | Ying Guo Guihua Zeng Yun Mao | 2006 | 通讯和计算机(中英文版)2006，3，7： | 1 |
| 15 | Joint remote state preparation of arbitrary two-and three-qubit states显示文摘 | Xiao Xiaoqi Liu Jinming Zeng Guihua | 2011 | Journal of Physics B:Atomic Molecular and Optical Physics2011，44，07： | 1 |
| 16 | Quantum secure communication using continuous variable Einstein-Podolsky-Rosen correlations显示文摘 | He Guangqiang Zhu Jun Zeng Guihua | | 0，，： | 1 |
| 17 | Arbitrated quantumsignature scheme 显示文摘 | Zeng Guihua Keitel Christoph H K | 2002 | Physics Review A2002，，： | 1 |
| 18 | Identity verification in quantum key distribution显示文摘 | Zeng Guihua Zhang Weiping | 2000 | Phys Rev A2000，61，： | 1 |
| 19 | Continuous variable quantum signature algorithm显示文摘 | Zeng Guihua Lee M Guo Ying | 2007 | International Journal of Quantum Information2007，5，3： | 1 |
| 20 | Propagation properties of Hermite-Cosine-Gaussian beams through a paraxial optical ABCD system with hard-edge aperture 显示文摘 | Zhou Nanrun Zeng Guihua | 2004 | Opt Commun2004，232，16： | 1 |
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