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	题名	作者	年代	出处	被引量
1	Role of the gut microbiota in inflammatory bowel disease pathogenesis: What have we learnt in the past 10 years?显示文摘Our understanding of the microbial involvement in inflammatory bowel disease(IBD) pathogenesis has increased exponentially over the past decade. The development of newer molecular tools for the global assessment of the gut microbiome and the identification of nucleotide-binding oligomerization domain-containing protein 2 in 2001 and other susceptibility genes for Crohn's disease in particular has led to better understanding of the aetiopathogenesis of IBD. The microbial studies have elaborated the normal composition of the gut microbiome and its perturbations in the setting of IBD. This altered microbiome or 'dysbiosis' is a key player in the protracted course of inflammation in IBD. Numerous genome-wide association studies have identified further genes involved in gastrointestinal innate immunity(including polymorphisms in genes involved in autophagy: ATG16L1 and IGRM), which have helped elucidate the relationship of the local innate immunity with the adjacent luminal bacteria. These developments have also spurred the search for specific pathogens which may have a role in the metamorphosis of the gut microbiome from a symbiotic entity to a putative pathogenic one. Here we review advances in our understanding of microbial involvement in IBD pathogenesis over the past 10 years and offer insight into how this will shape our therapeutic management of the disease in the coming years.	Georgina L Hold Megan Smith Charlie Grange Euan Robert Watt Emad M El-Omar Indrani Mukhopadhya	2014	World Journal of Gastroenterology2014，20，5：	21
2	Transferrin associated with the porcine intestinal mucosa is a receptor specific for K88ab fimbfiae of Escherichia coli显示文摘	Grange P A Mouricout M A	1996	Infect Immu1996，64，：	1
3	A ease of multiple myeloma with multilobulated and convoluted plasma cell muclei 显示文摘	Grange M J Fantin B Carbon C	1992	Nouv Rev Fr Hematol1992，34，：	1
4	Keshin - Beck disease and drinking water in Central Tibet 显示文摘	La Grange M Mathieu F Begaux F	2001	International Orthopaedics2001，25，3：	1
5	Investigation of the promotional effect of V205 on the SCR reaction and its mechanism on hybrid catalysts withV2O5and TiO2-SO42- catalysts 显示文摘	Jung S M Grange P	2002	Applied Catalysis B: Environmental2002，34，3：	1
6	Characterization and reactivity of V2O5-WO3 supported on TiO2-SO42-catalyst for the SCR reaction 显示文摘	Jung S M Grange P	2001	Applied Catalysis B : Environmental2001，32，12：	1
7	Influence of the impregnation order of molybdenum and cobalt in carbon-supported catalysts for hydrodeoxygenation reactions显示文摘	Ferrari M Delmon B Grange P		0，，：	1
8	Transferrin association with the porcine intestinal mucosa is a receptor specific for the F4ab fimbriae of Escherichia coli 显示文摘	GRANGE P A MOURICOUT M A	1996	Infect Immun1996，64，：	1
9	Photocatalytic degradation of phthalic acid on TiO2 nanoparticles显示文摘	JUNG S M DUPONT O GRANGE P	2001	Appi Catal A2001，208，：	1
10	Splicing factor and exon profiling across human tissues显示文摘	DE LA GRANGE P GRATADOU L DELORD M	2010	Nucleic Acids Res2010，38，9：	1
11	Coexpreasion of the Bacillus pumilus β-xylosidase (xynB) gene with the Trichoderma reesei β-xylanase 2 (xyn2) gene in the yeast Saccharomyces cerevisiae显示文摘	Grange D C L Claeyssem M Pretorius I S	2000	Appl Microbiol Biotechnol2000，54，：	1
12	Using a geographical information system to plan amalaria control programme in South Africa显示文摘	Booman M Durrheim DN Grange KL	2000	Bull WHO2000，78，：	1
13	Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche显示文摘	GRANGE C TAPPARO M COLLINO F	2011	Cancer Res2011，71，15：	1
14	Behavior and rupture of hydrided ZIRCALOY-4 tubes and sheets 显示文摘	Prat F Grange M Besson J Andrieu E	1998	Metallurgical and Materials Transactions A1998，29，6：	1
15	Antibacterial Properties of Propolis( bee glue) 显示文摘	Davey R W Grange J M	1990	J R Soc Med1990，83，：	1
16	The investigate of mechanism of SCR reaction on a TiO2-SO42- catalyst by DRIFTS 显示文摘	Jung S M Grange P	2000	Applied Catalysis B : Environmental2000，27，1：	1
17	Kashin-Beck disease anddrinking water in Central Tibet 显示文摘	La Grange M Mathieu F Begaux F	2001	Int Orthop2001，25，3：	1
18	Using a geographical information system to plan a malaria control programmein Soth Africa显示文摘	Booman M Durrheim DN La Grange K	2000	Bull World Health Organ2000，78，12：	1
19	Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatie niche显示文摘	Grange C Tapparo M Collino F	2011	Cancer Res2011，71，15：	1
20	Enantioselectiveα-benzylation of aldehydes via photoredox organocatalysis显示文摘	Shih H W Vander Wal M N Grange R L	2010	J Am Chem Soc2010，132，13：	1

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