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| 1 | National trends in resection of the distal pancreas显示文摘AIM:To investigate national trends in distal pancreatectomy(DP) through query of three national patient care databases.METHODS:From the Nationwide Inpatient Sample(NIS,2003-2009),the National Surgical Quality Improvement Project(NSQIP,2005-2010),and the Surveillance Epidemiology and End Results(SEER,2003-2009) databases using appropriate diagnostic and procedural codes we identified all patients with a diagnosis of a benign or malignant lesion of the body and/or tail of the pancreas that had undergone a partial or distal pancreatectomy.Utilization of laparoscopy was defined in NIS by the International Classification of Diseases,Ninth Revision correspondent procedure code;and in NSQIP by the exploratory laparoscopy or unlisted procedure current procedural terminology codes.In SEER,patients were identified by the International Classification of Diseases for Oncology,Third Edition diagnosis codes and the SEER Program Code Manual,third edition procedure codes.We analyzed the databases with respect to trends of inpatient outcome metrics,oncologic outcomes,and hospital volumes in patients with lesions of the neck and body of the pancreas that underwent operative resection.RESULTS:NIS,NSQIP and SEER identified 4242,2681 and 11 082 DP resections,respectively.Overall,laparoscopy was utilized in 15%(NIS) and 27%(NSQIP).No significant increase was seen over the course of the study.Resection was performed for malignancy in 59%(NIS) and 66%(NSQIP).Neither patient Body mass index nor comorbidities were associated with operative approach(P = 0.95 and P = 0.96,respectively).Mortality(3% vs 2%,P = 0.05) and reoperation(4% vs 4%,P = 1.0) was not different between laparoscopy and open groups.Overall complications(10% vs 15%,P < 0.001),hospital costs [44 741 dollars,interquartile range(IQR) 28 347-74 114 dollars vs 49 792 dollars,IQR 13 299-73 463,P = 0.02] and hospital length of stay(7 d,IQR 4-11 d vs 7 d,IQR 6-10,P < 0.001) were less when laparoscopy was utilized.One and two year survival after resection for malignancy were unchanged over the course of the study(ductal adenocarinoma 1-year 63.6% and 2-year 35.1%,P = 0.53;intraductal papillary mucinous neoplasm and nueroendocrine 1-year 90% and 2-year 84%,P = 0.25).The majority of resections were performed in teaching hospitals(77% NIS and 85% NSQIP),but minimally invasive surgery(MIS) was not more likely to be used in teaching hospitals(15% vs 14%,P = 0.26).Hospitals in the top decile for volume were more likely to be teaching hospitals than lower volume deciles(88% vs 43%,P < 0.001),but were no more likely to utilize MIS at resection.Complication rate in teaching and the top decile hospitals was not significantly decreased when compared to non-teaching(15% vs 14%,P = 0.72) and lower volume hospitals(14% vs 15%,P = 0.99).No difference was seen in the median number of lymph nodes and lymph node ratio in N1 disease when compared by year(P = 0.17 and P = 0.96,respectively).CONCLUSION:There appears to be an overall underutilization of laparoscopy for DP.Centralization does not appear to be occurring.Survival and lymph node harvest have not changed. | Armando Rosales-Velderrain Steven P Bowers Ross F Goldberg Tatyan M Clarke Mauricia A Buchanan John A Stauffer Horacio J Asbun | 2012 | World Journal of Gastroenterology2012，18，32： | 8 |
| 2 | The role of matrix metalloproteinases (MMPs) in human caries显示文摘 | Chaussain-Miller C Fioretti F Goldberg M | 2006 | J Dent Res2006，85，1： | 1 |
| 3 | A survey of optimization by building and using probabilistic models 显示文摘 | Pelikan M Goldberg D E and Lobo F G | 2002 | Computational Optimization and Applications2002，21，1： | 1 |
| 4 | Informal Caregiving and Self-reported Mental and Physical Health:Results from the Gazel Cohort Study 显示文摘 | Buyck J F Bonnaud S Boumendil A Andrieu S Bonenfant S Goldberg M Zins M and Ankri J | 2011 | American Journal of Public Health2011，101，： | 1 |
| 5 | Low-temperature wafer-scale productionof Zno nanowire aITays显示文摘 | Greene L E Law M Goldberger J Kim F Johnson J C Zhang Y F Saykally R J.Yang P D | | 0，，26： | 1 |
| 6 | Assessment of parasympathetic reactivation after exercise显示文摘 | Goldberger J J Le F K I ahiri M | 2006 | American Journal of Physiology- Heart and Circulatory Physiology2006，290，6： | 1 |
| 7 | A randomizedcontrolled trial of fluorouracil plus leucovorin,irinotecan,andoxaliplatin combinations in patients with previously untreatedmetastatic colorectal cancer显示文摘 | Goldberg R M Srgent DJ Mor ton R F | 2004 | J Clin Oncol2004，22，1： | 1 |
| 8 | The role of matrix metalloproteinases (MMPs) in human caries 显示文摘 | Chaussain-Miller C Fioretti F Goldberg M | 2006 | J Dent Res2006，85，： | 1 |
| 9 | Reinforcing effect of a resin glass ionomer in the restoration of immature roots in vitro显示文摘 | Goldberg F Kaplan A Roitmon M | 2002 | Dent Traumatc L2002，18，2： | 1 |
| 10 | A ran- domized controlled trial of fiuorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer 显示文摘 | Goldberg R M Sargent D J Morton R F | 2004 | J Clin Oncol2004，22，1： | 1 |
| 11 | Total-elbow arthroplasty显示文摘 | Goldberg V M Harry E F Cleveland O | 1988 | J Bone Joint Surg (Am)1988，70，： | 1 |
| 12 | The role of matrix metalloproteinases (MMPs) in human caries 显示文摘 | Chaussain Miller C Fioretti F Goldberg M | 2006 | J Dent Res2006，85，1： | 1 |
| 13 | Sequendng Medicagotruncatula expressed sequenced tag using 454 life sciences technology显示文摘 | Cheung F Haas B J Goldberg S M | 2006 | BMC Genomics2006，7，： | 1 |
| 14 | Colonic perforation and abscess following radiofreguency ablation treatment of hepatoma显示文摘 | Meloni M F Goldberg S N Moser V | 2002 | Eur J Ultrasound2002，15，12： | 1 |
| 15 | A randomized controlled trial of fluorouracil plus leucovorin,irinotecan,and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer显示文摘 | GOLDBERG R M SARGENT D J MORTON R F | 2004 | J Clin Oncol2004，22，1： | 1 |
| 16 | An investigation of student understanding of the real image formed converging lens or concave mirror显示文摘 | GOLDBERG F M McDERMOTT L C | 1987 | American Journal of Physics1987，55，2： | 1 |
| 17 | Hyperglycemia-induced mitochondrlal superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Splglycosylation显示文摘 | Du XL Edelstein D Rossetti L Fantus IG Goldberg H ziyadeh F Wu J Brownlee M | 2000 | Proc Natl Acad2000，97，12： | 1 |
| 18 | A survey of optimization by building and using probabilistic models显示文摘 | Pelikan M Goldberg D E Lobo F | 2002 | Computational Optimization and Apphcations2002，21，1： | 1 |
| 19 | A randomizedcontrolled trial of fluorouracil plus leuco-vorin, irinoteean, and oxaliplatin combi- nations in patients with previously un- treated metastatic colorectal cancer 显示文摘 | GOLDBERG R M SARGENT D J MORTON R F | 2004 | J Ctin Oncol2004，22，1： | 1 |
| 20 | Resistive training can reduce coronary risk factor swithout altering VO2max or percent body fat显示文摘 | Hurley B F Hagberg J M Goldberg A P | 1988 | Med Sci Sports Exerc1988，20，： | 1 |
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