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| 1 | B lymphocytes regulate airway granulocytic inflammation and cytokine production in a murine model of fungal allergic asthma显示文摘到真菌的促进感受性经常导致是特别地困难的临床上设法的气喘的一种严重形式,导致在这些病人的增加的病态和住院。尽管 B 淋巴细胞可能通过 IgE 的生产加重气喘症状,这些房间可能也在对吸入的真菌的保护的反应是重要的。通过 cytokine 版本和 T 房间相互作用,这些淋巴细胞可能也影响航线墙纤维变性的发展和维护。J H −/− 老鼠为抗体的重链部件缺乏 JH 基因,它为 B 房间功能和幸存是批评的。这些动物在很多有免疫力的回答便于 B 淋巴细胞的角色的说明;然而, J H −/− 老鼠没被用来学习真菌的过敏症。在这研究,我们用曲霉属菌 fumigatus 检验了 B 淋巴细胞的角色模仿被环境真菌的暴露触发的人的航线疾病的鼠科的真菌的高空过敏症模型。我们在敏化的野类型的 BALB/c 和 J 暴露于的 H −/− 老鼠重复了真菌的暴露并且没在大航线附近在航线 hyperresponsiveness,全面肺的发炎或骨胶原免职发现差别。然而, Th2 类型 cytokines IL-4 和 IL-13 的层次显著地在 J 相对 BALB/c 控制的 H −/− 鼠标。由对比,煽动性的 cytokines IL-17A 和 IL-6 的层次显著地在 J H −/− 动物,并且有显著地更柔韧的航线嗜曙红血球过多和 neutrophilia 比在控制动物。一起拿,这些调查结果表明淋巴细胞帮助在肺的分隔空间调整 granulocytic 回答到真菌的暴露的那 B。 | Sumit Ghosh Scott A Hoselton Scott V Asbach Breanne N Steffan Steve B Wanjara Glenn P Dorsam Jane M Schuh | 2015 | Cellular & Molecular Immunology2015，12，2： | 2 |
| 2 | Insular biogeography of mammals in Ca-nadian parks显示文摘 | Glenn S M Nudds T D | 1989 | Journal of Biogeography1989，16，3： | 1 |
| 3 | Multiple paternity and mating patterns in the American alligator,Alligator mississippiensis显示文摘 | Davis L M Glenn T C Elsey R M | 2001 | Molecular Ecology2001，10，： | 1 |
| 4 | Purification and characteriza-tion of an extracellular Mn(Ⅱ)-dependenperoxidasefrom the lignindegading basidiomycetes,Phancero-chaete chrysosporium显示文摘 | Glenn J K Gold M N | 1985 | Aich biochembiophys1985，242，： | 1 |
| 5 | Accuracy of sleep perceptions among insomnia sufferers and normal sleepers 显示文摘 | MEANS M K EDINGER J D GLENN D M | 2003 | Sleep Med2003，4，4： | 1 |
| 6 | Diverticulitis in California from 1995 to 2006: Increased Rates of Treatment for Younger Patients显示文摘 | Etzioni David A Cannom Rebecca R Ault Glenn T Beart Robert W Kaiser Andreas M | 2009 | The American Surgeon2009，，10： | 1 |
| 7 | Self-reported data from patients with bipolar disorder: frequency of brief depression 显示文摘 | Bauer M Glenn T Grof P | 2007 | J Affect Disord2007，101，13： | 1 |
| 8 | Acousto-Optic Tunable Flters: Fundamentals and Applications as Applied to Chemical Analysis Techniques显示文摘 | Ling B Glenn I D Heather M M | 2004 | Progress in Quantum Electronics2004，，28： | 1 |
| 9 | Fate of water soluble azo dyes in the activated sludge process显示文摘 | SHAUL Glenn M THOMAS J Holdsworth CLYDE R Dempsey Dostal KA | 1991 | Chemosphere1991，22，12： | 1 |
| 10 | Self-reported data from patients with bipolar disorder: frequency of brief depression显示文摘 | Bauer M Glenn T Grof P | 2007 | J Affect Disord2007，101，123： | 1 |
| 11 | Daytime testing after laboratory of home-base polysomnograply comparisons of middle-aged insomnia sufferers and normal sleepers显示文摘 | Edinger J O Glenn D M Bastian L A | 2003 | J sleep Res2003，12，1： | 1 |
| 12 | Sulfurcoated fertilizers for controlled release: pilot plant production 显示文摘 | Glenn M B Donald W R Oscar E M | 1971 | Agric Food Chem1971，19，5： | 1 |
| 13 | Templating Organic Semi- conductors via Self-assembly of Polymer Colloids显示文摘 | Raffaele M Janne R Glenn H | 2003 | Sci- ence2003，299，： | 1 |
| 14 | Halo- phytes for the treatment of saline aquaculture efflu- ent显示文摘 | Brown J Glenn E P Fitzsimmons K M | 1999 | Aquaculture1999，175，3： | 1 |
| 15 | Effect of sample size on ductility in electromagnetic expansion 显示文摘 | Tamhane Amit Altynova Marina M Daehn Glenn S | 1996 | Scripta Materialia1996，34，8： | 1 |
| 16 | The evolution of clinical significance显示文摘 | William C Follette Glenn M Callaghan | 2001 | Clinical psycholology:Science and Practice2001，8，4： | 1 |
| 17 | Changes in the risk of fine-root mortality with age:a case study in peach,Prunus persica(Rosaceae)显示文摘 | Wells C E Glenn D M Eissenstat D M | 2002 | American Journal of Botany2002，89，1： | 1 |
| 18 | Financing Constraints and Corporate Investment 显示文摘 | Fazzari Steven M R Glenn Hubbard Bruce C Petersen | 1988 | Brookings Paper on Economic Activity1988，19，1： | 1 |
| 19 | Von Hippel-Lindau disease显示文摘 | Lonser RR Glenn GM Walther M | 2003 | Lancet2003，361，9374： | 1 |
| 20 | Purification and Characterization of an Extra Cellular Mn(II)-dependent Peroxidase from the Lignin-degrading Basidiomycete 显示文摘 | Glenn J K Gold M H | 1985 | Archives of Biochemistry and Biophysics1985，242，2： | 1 |
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