|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Role of endoscopic therapy in early esophageal cancer显示文摘Esophageal carcinoma is a highly lethal cancer associated with high morbidity and mortality. Esophageal squamous cell carcinoma and esophageal adenocarcinoma are the two distinct histological types. There has been significant progress in endoscopic diagnosis and treatment of early stages of cancer using resection and ablation techniques, as shown in several trials in the recent past. Earlier detection of esophageal cancer and advances in treatment modalities have lead to improvement in the 5-year survival from 5% to about 20% in the past decade. Endoscopic eradication therapy is the preferred modality of treatment in cancer limited to mucosal layer of the esophagus as there is very low risk of lymph node metastasis, leading to high cure rates, low risk of recurrence and with few adverse effects. The most common adverse events seen are strictures, bleeding and rarely perforation which can be endoscopically managed. In patients with recurrent advanced disease or invasive tumor, esophagectomy with lymph node dissection remains the mainstay of treatment. There is debate on post-endoscopic surveillance with some studies suggesting closer follow up with upper endoscopy every 6 mo for the first 1-2 years and then annually for the 3 years while others recommending the appropriate action only if symptoms or other abnormalities develop. Overall, the field of endoscopic therapy is still evolving and focus should be placed on careful patient selection using a multidisciplinary approach. | Sonika Malik Gautam Sharma Madhusudhan R Sanaka Prashanthi N Thota | 2018 | World Journal of Gastroenterology2018，24，35： | 10 |
| 2 | Fhyroid hormone controls the gene expression of HSV-1 .AT and ICPO in neuronal cells显示文摘 | Gautam R Bedadala Rajeswara C Pirmoji Jayavardhana R Palem1, Shao-Chung V Hsia Shao-Chung V Hsia Jayavardhana R Palem | 2010 | Cell Research2010，20，5： | 6 |
| 3 | L3T4 CD4+ cells that mediate contact sensitivity to trinitrochlorobenzene express I-A determinants显示文摘 | Gautam SC Matriano JA Chikkala NF Edinger MG Tubbs R | 1991 | Cell Immunol1991，135，1： | 2 |
| 4 | Bewarel Fungal urosepsis may follow endoscopic intervention for prolonged indwelling ureteral stent显示文摘 | Gautam G Singh A K Kumar R | 2006 | J Endourol2006，20，7： | 1 |
| 5 | Maxillary protraction with and without maxillary expansion: A finite element analysis of sutural stresses显示文摘 | Gautam P Valiathan A Adhikari R | 2009 | Am J Orthod Dentofacial Orthop2009，136，3： | 1 |
| 6 | Anti-inflammatory, cy- elooxygenase (COX)-2, COX-1 inhibitory, and free radical scaven- ging effects of Rumex nepalensis 显示文摘 | Gautam R Karkhile KV Bhutani KK | 2010 | Planta Med2010，76，14： | 1 |
| 7 | Electrical,mechanical,and thermal properties of exfoliated graphite/phenolic resin composite bipolar plate for polymer electrolyte membrane fuel cell显示文摘 | Sykam N Gautam R K Kar K K | 2015 | Polymer Engineering&Science2015，55，4： | 1 |
| 8 | Gamma irradiation of municipal sludge for safe disposal and agricultural use显示文摘 | GAUTAM S SHAH M R SABHARWAL S | 2005 | Water Environment Research2005，77，5： | 1 |
| 9 | Nutrients, microbial community structure and functional gene abundanceof rhizosphere and bulk soils of halophytes显示文摘 | CHAUDHARY D R GAUTAM R K YOUSUF B | 2015 | Applied Soil Ecology2015，91，： | 1 |
| 10 | Drug therapy for idio-pathic male infertility:rationale versus evidence显示文摘 | Kumar R Gautam G Gupta NP | 2006 | J Urol2006，176，4： | 1 |
| 11 | Early Growth Response gene 1 (Egr-1) regulates HSV-1 ICP4 and ICP22 gene expression显示文摘调停的分子的机制疱疹 simplex 病毒类型 1 (HSV-1 ) 基因 silencing 不在潜伏性感染期间是清楚的。早生长反应基因 1 的五个拷贝(Egr-1 ) 有约束力的元素在 HSV-1 ICP22 (感染的细胞蛋白质号码 22 ) 的 intron 被识别基因,导致 Egr-1 绑在病毒的染色体并且调整的假设病毒的基因表示。短暂 co-transfection 试金显示 Egr-1 否定地调整了全身、移开 intron 的 ICP22 倡导者的抄写。一样的试金也揭示了那 Egr-1 镇压 ICP4 (感染的房间蛋白质号码 4 ) 以一种剂量依赖者方式的倡导者活动但是看了更少的抑制 intron 什么时候被移开。组蛋白 deacetylation 不后来涉及这条规定嘘一 deacetylase 禁止者 trichostatin A 没展出任何效果 onEgr-1-mediated 压抑。染色质免疫降水试金证明 Egr-1 把 Sp1 的绑定归结为倡导者并且合作抑压者 Nab2 (NGFI-A/EGR1-binding 蛋白质) 面对 Egr-1 被招募到 ICP4 的最近。这些结果建议多功能的抄写因素 Egr-1 能镇压 HSV-1 立即早通过合作抑压者 Nab2 的招募和 Sp1 占有的减小的基因表示,并且可以因此在潜伏期间在 HSV-1 基因 silencing 起一个关键作用。 | Gautam R Bedadala Rajeswara C Pinnoji Shao-Chung V Hsia | 2007 | Cell Research2007，17，6： | 1 |
| 12 | Drug therapy for idiopathic maleinfertility:rationale versus evidence显示文摘 | Kumar R Gautam G Gupta NP | 2006 | The Journal of Urology2006，，41： | 1 |
| 13 | Beware!Fungal urosepsis may follow endoscopic intervention for prolonged indwelling ureteral stent显示文摘 | Gautam G Singh AK Kumar R | 2006 | J Endoruol2006，20，7： | 1 |
| 14 | Renal tumor quantification and classification in contrast-enhanced abdominal CT显示文摘 | Linguraru MG Yao J Gautam R | 2009 | Patt Recog2009，42，6： | 1 |
| 15 | 显示文摘 | Rao C N R Deepak F L Gautam G | 2003 | Prog Solid State Chem2003，31，1： | 1 |
| 16 | Interest- based personalized search 显示文摘 | Zhongming Ma Gautam Pant Olivia R Liu Sheng | 2007 | ACM Transactions on Information Systems (TOIS)2007，25，1： | 1 |
| 17 | RRM1-induced metastasis suppression through PTEN-regulated pathways显示文摘 | Gautam A Li Z R Bepler G | | 0，，14： | 1 |
| 18 | Atomic-level dynamic behavior of a diffuse interphase boundary in an Au-Cu alloy 显示文摘 | Howe J M Gautam A R S Chatterjee K | 2007 | Acta Materialia2007，55，： | 1 |
| 19 | A solvothermal route to CdS nanocrystals显示文摘 | Gautam U K $eshadr R Rao C N R | 2003 | Chem Phys Lett2003，375，5： | 1 |
| 20 | Preparation of PbS and PbSe nanocrys- tals by a new solvothermal route 显示文摘 | Gautam U K Seshadri R | 2004 | Materials Research Bulletin2004，39，45： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员