|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Phase Ⅱ study of protracted irinotecan infusion and a low-dose cisplatin for metastatic gastric cancer显示文摘AIM: To test protracted irinotecan infusion plus a low-dose cisplatin in this Phase Ⅱ trial to decrease its toxic-ity. METHODS: The eligibility criteria were: (1) histologi-cally proven measurable gastric cancer; (2) performance status of 0 or 1; (3) no prior chemotherapy or comple-tion of prior therapy at least 4 wk before enrollment; (4) adequate function of major organs; (5) no other active malignancy; and (6) written informed consent. The regi-men consisted of irinotecan (60 mg/m2) on d 1 and 15 by 24-h infusion and cisplatin (10 mg/m2) on d 1, 2, 3, 15, 16, and 17. Treatment was repeated every 4 wk. RESULTS: Thirty-one patients were registered between April 2000 and January 2001. The response rate for all 31 patients, 20 patients without prior chemotherapy, and 11 patients with prior chemotherapy was 52% (16/31), 60% (12/20), and 36% (4/11), respectively. The median survival time was 378 d. The median number of courses given to all patients was 2. Grade 4 neutropenia oc-curred in 11 (35%) patients, while grade 3 to 4 diarrhea or nausea occurred in 1 (3%) and 3 (10%) patients, respectively. Fatigue was minimal as grade 1 fatigue was found only in 3 (10%) patients. Other adverse events were mild and no treatment-related deaths occurred.CONCLUSION: This regimen showed a high level of ac-tivity and acceptable toxicity in patients with metastatic gastric cancer. | Hiroshi Imamura Masataka Ikeda Hiroshi Furukawa Toshimasa Tsujinaka Kazumasa Fujitani Kenji Kobayashi Hiroyuki Narahara Michio Kato Haruhiko Imamoto Arimichi Takabayashi Hideaki Tsukuma | 2006 | World Journal of Gastroenterology2006，12，40： | 7 |
| 2 | 单晶Au表面和Au/TiO_2(110)模型催化剂表面CO氧化反应机理和活性位(英文)显示文摘在分子尺度上介绍了Au/TiO_2(110)模型催化剂表面和单晶Au表面CO氧化反应机理和活性位、以及H_2O的作用.在低温(<320 K),H_2O起着促进CO氧化的作用,CO氧化的活性位位于金纳米颗粒与TiO_2载体界面(Au^(δ+)O^(δ–)––Ti)的周边.O_2和H_2O在金纳米颗粒与Ti O_2载体界面边缘处反应形成OOH,而形成的OOH使O–O键活化,随后OOH与CO反应生成CO_2.300K时CO_2的形成速率受限于O_2压力与该反应机理相印证.相反,在高温(>320 K)下,因暴露于CO中而导致催化剂表面重组,在表面形成低配位金原子.低配位的金原子吸附O_2,随后O_2解离,并在金属金表面氧化CO. | Tadahiro Fujitani Isao Nakamura | 2016 | Chinese Journal of Catalysis2016，37，10： | 2 |
| 3 | Bacteriocin production of probiotic Lactobacillus gasseri LA39 isolated from human feces in milk-based media显示文摘 | ARAKAWA K FUJITANI K NISHIMURA J | 2008 | Animal Science Journal2008，79，5： | 1 |
| 4 | RGMa inhibition promotes axonal growth and recovery after spinal cord injury显示文摘 | Hata K Fujitani M Yasuda Y | 2006 | J Cell Biol2006，173，1： | 1 |
| 5 | Diverse functions of the P75 neurotrophin receptor显示文摘 | Yamashita T Fujitani M Hata K et at | 2005 | Anat Sci Int2005，80，1： | 1 |
| 6 | Effect of acid etching on the dental pulp in adhesive composite restorations显示文摘 | Fujitani M Inokoshi S Hosoda H | 1992 | Int Dent J1992，42，1： | 1 |
| 7 | Development of anactive Ga2O3 supported palladium catalyst for the synthesis of methanol from carbon dioxide and hydrogen显示文摘 | Fujitani T Satio M Kanai Y | 1995 | Appl Catal1995，125，2： | 1 |
| 8 | Several Recent Circuits in the Small Power UPS System 显示文摘 | Nakamura M Fujitani Y Kawauchi S | 1995 | National Convention Record1995，2，122： | 1 |
| 9 | Endothelin receptor antagonists inhibit antigen-induced lung inflammation in mice 显示文摘 | Fujitani Y Trifilieff A Tsuyuki S | 1997 | Am J Respir Crit Care Med1997，155，6： | 1 |
| 10 | Performance of an exterior metal curtain wall inseismic responses of a high-rise building显示文摘 | Nagae Takuya Fujitani Hideo Fukuyama Kunio KidoShirou | 2010 | AIJ Journalof Technology and Design2010，16，33： | 1 |
| 11 | Zonal and vertical distribution of radiolarians in the western and central Equatorial Pacific in January 1999显示文摘 | YAMASHITA H TAKAHASHI K FUJITANI N | 2002 | Deep Sea Res Ⅱ2002，，： | 1 |
| 12 | Leucine promotes glucose uptake in skeletal muscles of rats显示文摘 | NISHITANI S MATSUMURA T FUJITANI S | 2002 | Biochem Biophys Res Commun2002，299，： | 1 |
| 13 | Adsorption behavior of dispersing agent to pigment surface显示文摘 | Noboru Nakai Atsunao Hiwara Toshihide Fujitani | 2001 | Studies in surface science and catalysis2001，132，： | 1 |
| 14 | Glycotentacles:synthesis of cyclic glycopeptides,toward a tailored blocker of influenza virus hemagglutinin显示文摘 | Ohta T Miura N Fujitani N | 2003 | Angew Chem Int Ed2003，42，： | 1 |
| 15 | Flame retardant tetrabromobisphenol A induced hepatic changes in ICR male mice显示文摘 | Yukie Tada Tomoko Fujitani Akio Ogata | 2007 | Environmental Toxicology and Pharmacology2007，23，： | 1 |
| 16 | Discovery of Atg5/Atg7-independent alternative macroautophagy显示文摘 | Nishida Y Arakawa S Fujitani K | 2009 | Nat2009，461，7264： | 1 |
| 17 | 胃切除术联合化疗与单纯化疗在具有一种单一不可治愈因素的进展期胃癌患者中的疗效对比研究(REGATTA):一项Ⅲ期随机对照研究显示文摘【摘要】背景和目的化疗是不可治愈进展期胃癌的标准治疗方案。对于具有一个单一不可治愈因素的进展期胃癌患者,姑息性胃切除术后加化疗能否提高此类患者的生存尚存争议。本研究目的是探讨姑息性胃切除术后化疗能否比单纯化疗在提高此类患者总体生存上更有优势。方法本研究是一项多中心、开放、随机、对照、Ⅲ期临床研究,包括日本、韩国、新加坡44个研究中心。患者是年龄20~75岁的具有一个单一不可治愈因素的进展期胃癌患者,这些不可治愈因素包括有局限于肝(H1)、腹膜(P1)、或腹主动脉旁淋巴结(16a1/b2)的转移。 | Fujitani K Yang HK Mizusawa J 戴伟钢 蔡世荣 | 2016 | 消化肿瘤杂志(电子版)2016，8，3： | 1 |
| 18 | P311 accelerates nerveregeneration of the axotomized facial nerve显示文摘 | FUJITANI M YAMAGISHI S CHE YH | 2004 | Neurochem2004，91，3： | 1 |
| 19 | A reevaluation of intra-arterial thrombolytic therapy for actue lower extremity ischemia显示文摘 | DeMaioribus CA Mills JL Fujitani RM | 1993 | J Vasc Surg1993，17，5： | 1 |
| 20 | Effect of support on methanol synthesis over Cu catalyst显示文摘 | Fujitani T Saito M Kanai Y | 1994 | Chem Lett1994，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员