|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Role of polyethylene particles in peri-prosthetic osteolysis:A review显示文摘There is convincing evidence that particles produced by the wear of joint prostheses are causal in the periprosthetic loss of bone,or osteolysis,which,if it progresses,leads to the phenomenon of aseptic loosening.It is important to fully understand the biology of this bone loss because it threatens prosthesis survival,and loosened implants can result in peri-prosthetic fracture,which is disastrous for the patient and presents a difficult surgical scenario.The focus of this review is the bioactivity of polyethylene(PE)particles,since there is evidence that these are major players in the development and progression of osteolysis around prostheses which use PE as the bearing surface.The review describes the biological consequences of interaction of PE particles with macrophages,osteoclasts and cells of the osteoblast lineage,including osteocytes.It explores the possible cellular mechanisms of action of PE and seeks to use the findings to date to propose potential nonsurgical treatments for osteolysis.In particular,a nonsurgical approach is likely to be applicable to implants containing newer,highly cross-linked PEs(HXLPEs),for which osteolysis seems to occur with much reduced PE wear compared with conventional PEs.The caveat here is that we know little as yet about the bioactivity of HXLPE particles and addressing this constitutes our next challenge. | Gerald J Atkins David R Haynes Donald W Howie David M Findlay | 2011 | World Journal of Orthopedics2011，2，10： | 11 |
| 2 | Edge termination for very high voltage IGBT devices显示文摘 | Coulbeck L | 1997 | IPEMC''971997，1，： | 1 |
| 3 | Quantification of class1 integron abundance in natural environments using real time quantitative PCR显示文摘 | Hardwick S A Stokes H W Findlay S etal | 2008 | J FEMS Microbiol Lett2008，278，2： | 1 |
| 4 | Soil and phosphorus loss in conservation and conventional tillage in eom production显示文摘 | Adelaide-Gaynor L D Findlay W L | 1995 | Journal Environment Quality1995，24，： | 1 |
| 5 | Familial adrenocorticotropin-independent Cushing's syndrome with bilateral macronodular adrenal hyperplasia显示文摘 | Findlay J C Sheeler L R Engeland W C | 1993 | J Clin Endocrinol Metab1993，76，： | 1 |
| 6 | Relationships a- mong photosynthetic rate, bean yield and other character sing field - grown cuhivars of soybean 显示文摘 | Buttery B R Buzzell R I Findlay W I | 1980 | Can J Plant Sci1980，61，： | 1 |
| 7 | Target recognition by calmodulin : Dissecting the kinetics and affinity of interaction using short peptide sequences 显示文摘 | P M Bayley W A Findlay S R Martin | 1996 | Protein Science1996，5，： | 1 |
| 8 | Thermomechanical properties of beef muscle 显示文摘 | C J Findlay D W Stanley E A Gullett | 1986 | Meat Science1986，16，： | 1 |
| 9 | Eutroph- ication oflakes cannot be controlled by reducing nitrogen input: Results of a 37 -year whole-ecosystem experiment 显示文摘 | SCHINDLER D W HECKY R E FINDLAY D L | 2008 | Proceedings of the National Academy of Sciences of the United States of America2008，105，11： | 1 |
| 10 | Eutrophication of lakes cannot be controlled by reducing nitrogen input:Results of a 37-year whole-ecosystem experiment显示文摘 | Schindler D W Hecky R E Findlay D L | | 0，，： | 1 |
| 11 | The proliferation and phenotypic expression of human osteoblasts on tantalum metal显示文摘 | David M Findlay Katie Welldon Gerald J Atkins Donald W Howie Andrew C.W Zannettino Dennis Bobyn | 2003 | Biomaterials2003，，12： | 1 |
| 12 | Bioanalytical method validation a revisit with a decade of progress 显示文摘 | SHAH V P MIDHA K K FINDLAY J W A | 2000 | Pharmaceutical Research2000，17，12： | 1 |
| 13 | Eutrophication of lakes cannot be controlled by reducing nitrogen input:Results of a 37-year whole-ecosystem experiment显示文摘 | Schindler D W Hecky R E Findlay D L | | 0，，： | 1 |
| 14 | Interferometric observations on far infra-red stimulated emissioin sources显示文摘 | GEBBIE H A STONE N W B FINDLAY F D | 1964 | Nature1964，202，： | 1 |
| 15 | Enhanced transdermal delivery of testosterone across nonscrotal skin produces physiological concentrations of testosterone and its metabolites in hypogonadal men显示文摘 | Meikle A W Findlay J C Korenman S G | 1991 | J Clin Endocrinol Metab1991，74，1： | 1 |
| 16 | Bioanalytical method validation-A revisit with a decade of progress 显示文摘 | SHAH V P MIDHA K K FINDLAY J W | 2000 | Pharm Res2000，17，2： | 1 |
| 17 | Eutrophi-cation of lakes cannot be controlled by reducing nitrogen input: Results of a 37-year whole-ecosystem experiment 显示文摘 | Schindler D W Hecky R E Findlay D L | 2008 | Proceedings of the National Academy of Sciences2008，105，11： | 1 |
| 18 | Approaches to water-soluble aliphatic hyperbranched polyamides显示文摘 | Feast W J Findlay A P | 2001 | Polymeric Mater- ials: Science and Engineering2001，84，： | 1 |
| 19 | Microbial Bio- mass and Soil Structure Associated with Corn, Gras- ses, and Legumes显示文摘 | F Drury C A Stone J I Findlay W | 1991 | Soil Science Society of America Journal1991，，3： | 1 |
| 20 | Soil and phosphorus loss from conservation and conventional tillage in corn production显示文摘 | GAYNOR J D FINDLAY W I | 1995 | Environmental Quality1995，24，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员