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| 1 | The liver works as a school to educate regulatory immune cells显示文摘因为它的唯一的血供应,肝维持特殊本地有免疫力的 tolerogenic 微型环境。而且,肝能在另外的机关上给予这有免疫力的 tolerogenic 效果,因此导致全身的有免疫力的忍耐。肝的规章的房间的网络是位于肝忍耐下面的重要机制。肝居民的许多类型介绍抗原的房间(APC ) 有有免疫力的规章的功能,并且更重要地,他们装也导致传播有免疫力的房间的区别进规章的房间进一步扩大全身的忍耐。因此,肝能被看作 ‘ 的一种类型; school’,在肝 APC 作为 ‘ 工作的地方; teachers’并且传播有免疫力的房间作为 ‘ 工作;学生 .’ | Fenglei Li Zhigang Tian | 2013 | Cellular & Molecular Immunology2013，10，4： | 15 |
| 2 | Investigating the dynamic mechanical behaviors of polyurea through experimentation and modeling显示文摘Polyurea is widely employed as a protective coating in many fields because of its superior ability to improve the anti-blast and anti-impact capability of structures.In this study,the mechanical properties of polyurea XS-350 were investigated via systematic experimentation over a wide range of strain rates(0.001-7000 s^-1)by using an MTS,Instron VHS,and split-Hopkinson bars.The stress-strain behavior of polyurea was obtained for various strain rates,and the effects of strain rate on the primary mechanical properties were analyzed.Additionally,a modified rate-dependent constitutive model is proposed based on the nine-parameter Mooney-Rivlin model.The results show that the stress-strain curves can be divided into three distinct regions:the linear-elastic stage,the highly elastic stage,and an approximate linear region terminating in fracture.The mechanical properties of the polyurea material were found to be highly dependent on the strain rate.Furthermore,a comparison between model predictions and the experimental stress-strain curves demonstrated that the proposed model can characterize the mechanical properties of polyurea over a wide range of strain rates. | Hao Wang Ximin Deng Haijun Wu Aiguo Pi Jinzhu Li Fenglei Huang | 2019 | Defence Technology(防务技术)2019，15，6： | 13 |
| 3 | Water droplet impact on superhydrophobic surfaces with microstructures and hierarchical roughness显示文摘Quantitative correlation between the critical impact velocity of droplet and geometry of superhydrophobic surfaces with microstructures is systematically studied.Experimental data shows that the critical impact velocity induced wetting transition of droplet on the superhydrophobic surfaces is strongly determined by the perimeter of single micropillar,the space between the repeat pillars and the advancing contact angle of the sidewall of the micropillars.The proposed model agrees well with the experimental results,and clarifies that the underlying mechanism which is responsible for the superhydrophobic surface with hierarchical roughness could sustain a higher liquid pressure than the surfaces with microstructures. | HAO PengFei LV CunJing NIU FengLei YU Yu | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，7： | 11 |
| 4 | Methods of rapid orbit forecasting after maneuvers for geostationary satellites显示文摘A geostationary(GEO) satellite may serve as a navigation satellite,but there is a problem that maneuvers frequently occur and the forces are difficult to model.Based on the technique of determining satellite orbits by transfer,a predicted orbit with high accuracy may be achieved by the method of statis-tical orbit determination in case of no maneuver force.The predicted orbit will soon be invalid after the maneuver starts,and it takes a long time to get a valid orbit after the maneuver ends.In order to improve ephemeris usability,the method of rapid orbit forecasting after maneuvers is studied.First,GEO satellite movement is analyzed in case of maneuvers based on the observation from the orbit meas-urement system by transfer.Then when a GEO satellite is in the free status just after maneuvers,the short arc observation is used to forecast the orbit.It is assumed that the common system bias and biases of each station are constant,which can be obtained from orbit determination with long arc observations.In this way,only 6 orbit elements would be solved by the method of statistical orbit determination,and the ephemeris with high accuracy may be soon obtained.Actual orbit forecasting with short arc observation for SINOSAT-1 satellite shows that,with the tracking network available,the precision of the predicted orbit(RMS of O-C) can reach about 5 m with 15 min arc observation,and about 3 m with 30 min arc observation. | YANG XuHai LI ZhiGang FENG ChuGang GUO Ji SHI HuLi AI GuoXiang WU FengLei QIAO RongChuan | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，3： | 10 |
| 5 | Jet formation and penetration mechanism of W typed shaped charge显示文摘Existing classical shaped charges are well knownfor their longer jets capable of achieving large hole depth tohole diameter ratios in metallic targets.However,in some sit-uations,there arises demand to obtain 1:1 ratio for hole depthto hole diameter which is beyond normal shaped chargescapability.A new variant of shape charge,named W typedshape charge(WSC),is proposed in this paper,which canmeet the demand of 1:1 ratio,and is based on the geometrythat can produce annular jets upon proper initiation scheme.In this paper,we present formation and penetration resultsof WSC based on three different schemes.We also showthat not all WSC designs can form annular jets,only annu-larly initiated WSC,which also fulfils the 'Internal-ExternalLiners Equal-Impulse' criterion,has the capability to formannular jet.The experimental and numerical results show thatwhen the ratio between annular initiation ring diameter andthe charge diameter is 0.75,an annular jet is formed,whichwas also supported by high speed photographs performedin vacuum.2D numerical simulations are performed withindigenously developed simulation software,where Eulerianapproach with multi-material interface tracking algorithm isutilized,to find various mechanisms involved during jet for-mation process.The calculation results are found in goodagreement with the experimental results,indicating that theinterface treatment algorithm proposed in this paper can notonly deal with large deformation problem,but also depictclearly the variation of materials interface.It is especially suitable for simulation of the process from liner collapse toformation of shaped charge jet. | Cheng Wang Fenglei Huang Jianguo Ning State Key Laboratory of Explosion Science and Technology,Beijing Institute of Technology, 100081 Beijing, China | 2009 | Acta Mechanica Sinica2009，25，1： | 7 |
| 6 | Quasi-static tensile deformation and fracture behavior of a highly particle-filled composite using digital image correlation method显示文摘Polymer bonded explosives (PBXs) are highly particle-filled composite materials.This paper experimentally studies the tensile deformation and fracture behavior of a PBX simulation by using the semi-circular bending (SCB) test.The deformation and fracture process of a pre-notched SCB sample with a random speckle pattern is recorded by a charge coupled device camera.The displacement and strain fields on the observed surface during the loading process are obtained by using the digital image correlation method.The crack opening displacement is calculated from the displacement fields,the initiation and propagation of the crack are analyzed.In addition,the damage evolution and fracture mechanisms of the SCB sample are analyzed according to the strain fields and the correlation coefficient fields at different loading steps. | Zhongbin Zhou,Pengwan Chen,Baoqiao Guo,Zhuoping Duan,and Fenglei Huang State Key Laboratory of Explosion Science and Technology,Beijing Institute of Technology,Beijing 100081,China | 2011 | Theoretical & Applied Mechanics Letters2011，1，5： | 5 |
| 7 | Impervious surface extraction based on different methods from multiple spatial resolution images:a comprehensive comparison显示文摘Many efforts have been devoted to extracting impervious surfaces based on different methods from multiple spatial resolution images.Differences in extraction methods and spatial resolutions are significant and have led to discrepant performances in terms of the impervious surface extraction accuracy.However,which extraction method is more suitable for which kind of spatial resolution image in practice is poorly understood.This study systematically compared the performances of 12 methods of impervious surface extraction for four spatial resolution images(i.e.Landsat 8[30 m],Sentinel-2A[20 m],Sentinel-2A[10 m],and Gaofen-2[4 m])in three testing areas.The results indicated that for the mediumspatial resolutions of 30 and 20 m,the support vector machine(SVM)method was considered as the optimal classification method with the highest accuracy of impervious surface extraction.For the high-spatial resolutions of 10 and 4 m,the object based image analysis(OBIA)method obtained the highest accuracy of the impervious surface distribution.Furthermore,the perpendicular impervious surface index(PISI)outperformed the other indices in obtaining the impervious surface distribution,with the highest accuracy for four spatial resolution images.These comprehensive assessments can provide a valuable guidance for future impervious surface extraction from different spatial resolutions. | Shanshan Feng Fenglei Fan | 2021 | International Journal of Digital Earth2021，14，9： | 4 |
| 8 | A thermal-mechanical constitutive model for b-HMX single crystal and cohesive interface under dynamic high pressure loading显示文摘Due to the significant thermal-mechanical effects during hot spot formation in PBX explosives,a thermodynamic constitutive model has been constructed for HMX anisotropic single crystal subjected to dynamic impact loading. The crystal plasticity model based on dislocation dynamics theory was employed to describe the anisotropic plastic behavior along the preferential slip systems. A modified equation of state (EOS) was introduced into the constitutive equations through the decomposing stress tensor and the nonlinear elasticity for materials was taken into account. The one-dimensional strain impact simulations for HMX single crystal and quasi-bicrystal were performed respectively,in which the cohesive elements were inserted over the interface areas for the latter. The predicted particle velocities for the single crystal sample agreed well with the experimental results in the literature. Furthermore,the effects of crystal orientations,interface,misorientations on localized strain,stress and temperature distributions were predicted and discussed. | WU YanQing & HUANG FengLei State Key Laboratory of Explosion Science and Technology,Beijing Institute of Technology,Beijing 100081,China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，2： | 4 |
| 9 | Porous Pt nanoframes decorated with Bi(OH)3 as highly efficient and stable electrocatalyst for ethanol oxidation reaction显示文摘High-quality Pt-based catalysts are highly desirable for ethanol oxidation reaction(EOR),which is of critical importance for the commercial applications of direct ethanol fuel cells(DEFCs).However,most of the Pt-based catalysts have suffered from high cost and low operation durability.Herein a two-step method has been developed to synthesize porous Pt nanoframes decorated with Bi(OH)3,which show excellent catalytic activity and operation durability in both alkaline and acidic media.For example,the nanoframes show a mass activity of 6.87 A·mgPt−1 in alkaline media,which is 13.5-fold higher than that of commercial Pt/C.More importantly,the catalyst can be reactivated simply,which shows negligible activity loss after running for 180,000 s.Further in situ attenuated total reflection-infrared(ATR-IR)absorption spectroscopy and CO-stripping experiments indicate that surface Bi(OH)3 species can greatly facilitate the formation of adsorbed OH species and subsequently remove carbonaceous poison,resulting in a significantly enhanced stability towards EOR.This work may favor the tailoring of desired electrocatalysts with high activity and durability for future commercial application of DEFCs. | Xiaolei Yuan Bei Jiang Muhan Cao Congyang Zhang Xiaozhi Liu Qinghua Zhang Fenglei Lyu Lin Gu Qiao Zhang | 2020 | Nano Research2020，13，1： | 3 |
| 10 | Health-related quality of life among rural residents aged 45-69 years in Hua County, Henan Province, China: Results of ESECC Trial for esophageal cancer screening with endoscopy显示文摘Objective: There have been few population-based studies evaluating health related quality of life(HRQOL) in rural populations in China, and this study aimed to assess the current status of and risk factors for HRQOL in a general rural population in high risk region of esophageal cancer in China.Methods: From November 2015 to September 2016, 12,085 permanent residents aged 45–69 years from 257 villages in the Endoscopic Screening for Esophageal Cancer in China(ESECC) trial(Clinical Trials.gov:NCT01688908) randomly selected from Hua County, Henan Province, China were interviewed. The EQ-5 D-3 L,a generic measure of HRQOL, and a questionnaire were used to assess their HRQOL and potential risk factors.Results: Among all the participants, 30.62% of the participants reported problems in at least one EQ-5 D dimension. Pain/discomfort(25.52%) was the most frequently reported problem followed by anxiety/depression(7.97%), mobility(5.82%), usual activities(2.61%) and self-care(1%). These rural residents had a mean EQ-5 D index score of 0.948, and lower EQ-5 D index scores were associated with older age, female gender, lower levels of household annual per capita income, living alone, using shallow wells as main source of drinking water, exposure to family members smoking, testiness, unhealthy dietary habits, overweight or obesity, upper gastrointestinal cancer related symptoms and chronic diseases.Conclusions: Rural residents in China have a relatively low quality of life. Health promotion programs in this population should focus on the elderly, especially elderly women and the elderly living alone. Improving basic living circumstances and primary medical care services should be priorities. Results of this study will also serve as the basis for the cost-utility evaluation in our ESECC screening trial. | Hui Wang Yaqi Pan Chuanhai Guo Fenglei Li Ruiping Xu Mengfei Liu Zhen Liu Fangfang Liu Hong Cai Yang Ke Zhonghu He | 2018 | Chinese Journal of Cancer Research2018，30，2： | 3 |
| 11 | Oral microbiome and risk of malignant esophageal lesions in a high-risk area of China:A nested case-control study显示文摘Objective:We aimed to prospectively evaluate the association of oral microbiome with malignant esophageal lesions and its predictive potential as a biomarker of risk.Methods:We conducted a case-control study nested within a population-based cohort with up to 8 visits of oral swab collection for each subject over an 11-year period in a high-risk area for esophageal cancer in China.The oral microbiome was evaluated with 16 S ribosomal RNA(rRNA)gene sequencing in 428 pre-diagnostic oral specimens from 84 cases with esophageal lesions of severe squamous dysplasia and above(SDA)and 168 matched healthy controls.DESeq analysis was performed to identify taxa of differential abundance.Differential oral species together with subject characteristics were evaluated for their potential in predicting SDA risk by constructing conditional logistic regression models.Results:A total of 125 taxa including 37 named species showed significantly different abundance between SDA cases and controls(all P<0.05&false discovery rate-adjusted Q<0.10).A multivariate logistic model including 11 SDA lesion-related species and family history of esophageal cancer provided an area under the receiver operating characteristic curve(AUC)of 0.89(95%CI,0.84-0.93).Cross-validation and sensitivity analysis,excluding cases diagnosed within 1 year of collection of the baseline specimen and their matched controls,or restriction to screenendoscopic-detected or clinically diagnosed case-control triads,or using only bacterial data measured at the baseline,yielded AUCs>0.84.Conclusions:The oral microbiome may play an etiological and predictive role in esophageal cancer,and it holds promise as a non-invasive early warning biomarker for risk stratification for esophageal cancer screening programs. | Fangfang Liu Mengfei Liu Ying Liu Chuanhai Guo Yunlai Zhou Fenglei Li Ruiping Xu Zhen Liu Qiuju Deng Xiang Li Chaoting Zhang Yaqi Pan Tao Ning Xiao Dong Zhe Hu Huanyu Bao Hong Cai Isabel Dos Santos Silva Zhonghu He Yang Ke | 2020 | Chinese Journal of Cancer Research2020，32，6： | 3 |
| 12 | Interaction of Caffeine with Bovine Serum Albumin: Determination of Binding Constants and the Binding Site by Spectroscopic Methods显示文摘 | Wu, Qiong Jiang, Fenglei Li, Chaohong Hu, Yanjun Liu, Yi | 2011 | Chinese Journal of Chemistry2011，29，3： | 3 |
| 13 | A novel random phase-shifting digital holographic microscopy method显示文摘This paper proposes a new method that reconstructs the information of specimen by using random phase shift step in digital holographic microscopy (DHM). The principles of the method are described and discussed in detail. In practical experiment, because the phase shifter is neither perfectly linear nor calibrated, digital holograms with inaccurate phase shift step are recorded by the charge-coupled device (CCD). The phase could be accurately reconstructed from the recorded digital holograms by using the random phase-shifting algorithm, which makes up for reconstructed phase error caused by ordinary phase-shifting algorithm. The phase aberration compensation is also discussed. In order to verify the flexibility of the proposed method, numerical simulation of random phase-shifting DHM was carried out. The simulation results illustrated that the presented method is effective when the phase shift step is unknown or random in DHM. | HuiMin Xie ZhenXing Hu FuLong Dai YanJie Li PengWan Chen QingMing Zhang FengLei Huang | 2009 | Science China(Technological Sciences)2009，52，7： | 3 |
| 14 | Identification of cancer patients using claims data from health insurance systems: A real-world comparative study显示文摘Objective: To evaluate the accuracy of identifying cancer patients by use of medical claims data in a health insurance system in China, and provide the basis for establishing the claims-based cancer surveillance system in China.Methods: We chose Hua County, Henan Province as the study site, and randomly selected 300 and 1,200 qualified inpatient electronic medical records(EMRs) as well as the New Rural Cooperative Medical Scheme(NCMS) claims records for cancer patients in Hua County People’s Hospital(HCPH) and Anyang Cancer Hospital(ACH) in 2017. Diagnostic information for NCMS claims was evaluated on an individual level, and sensitivity and positive predictive value(PPV) were calculated taking the EMRs as the gold standard.Results: The sensitivity of NCMS was 95.2%(93.8%-96.3%) and 92.0%(88.3%-94.8%) in ACH and HCPH,respectively. The PPV of the NCMS was 97.8%(96.7%-98.5%) in ACH and 89.0%(84.9%-92.3%) in HCPH.Overall, the weighted and combined sensitivity and PPV of NCMS in Hua County was 93.1% and 92.1%,respectively. Significantly higher sensitivity and PPV in identifying patients with common cancers than noncommon cancers were detected in HCPH and ACH separately(P<0.01).Conclusions: Identification of cancer patients by use of the NCMS is accurate on individual level, and it is therefore feasible to conduct claims-based cancer surveillance in areas not covered by cancer registries in China. | Hongrui Tian Ruiping Xu Fenglei Li Chuanhai Guo Lixin Zhang Zhen Liu Mengfei Liu Yaqi Pan Zhonghu He Yang Ke | 2019 | Chinese Journal of Cancer Research2019，31，4： | 3 |
| 15 | Preparation of Diamond-like Carbon Films on the Surface of Ti Alloy by Electro-deposition显示文摘In this paper, diamond-like carbon (DLC) fi[ms were deposited on Ti alloy by electro-deposition. DLC films were brown and composed of the compact grains whose diameter was about 400 nm. Examined by XPS, the main composition of the films was carbon. In the Raman spectrum, there were a broad peak at 1350 cm-1 and a broad peak at 1600 cm-1, which indicated that the films were DLC films. | Fenglei SHEN Hongwei WANG Dijiang WEN School of Materials Engineering,Suzhou University,Suzhou 215021,China | 2004 | Journal of Materials Science & Technology2004，20，3： | 3 |
| 16 | Biophysical studies of the interaction between a triazole derivative and bovine serum albumin by multi-spectroscopic and molecular modeling methods显示文摘The interaction between 3-thiol-4-(2,4-dichlorobenzylideneamino)-5-methyl-4H-1,2,4-triazole (CBTZ) and bovine serum albumin (BSA) under physiological conditions was investigated by fluorescence,UV-vis absorption and circular dichroism (CD) spectroscopy as well as molecular modeling methods. The result of fluorescence experiment indicates the static quenching as a result of the formation of the CBTZ-BSA complex. The binding constants (Ka) at different temperatures were calculated according to the modified Stern-Volmer equation. The enthalpy change (-H) and entropy change (-S) were determined based on the van′t Hoff equation. Both negative-H and-S indicated that van der Waals and hydrogen-bonding forces were the dominant intermolecular forces to stabilize the CBTZ-BSA complex. Site marker competitive replacement experiments demonstrated that binding of CBTZ to BSA primarily took place in sub-domain IIA (Sudlow's site I). The binding distance (r = 7.2 nm) between CBTZ and the tryptophan residue of BSA was estimated according to the theory of fluorescence resonance energy transfer (FRET). The conformational studies by circular dichroism (CD) and three-dimensional fluorescence spectroscopy showed that the presence of CBTZ induced minor changes of the secondary structure of BSA. Molecular modeling study further confirmed the binding mode obtained experimentally. | FU JiaXin WANG KaiWei GE YuShu JIANG FengLei SUN XiaoHong LIU Yang LIU Yi | 2011 | Science China Chemistry2011，54，5： | 2 |
| 17 | High-efficiency acetaldehyde removal during solid-state polycondensation of poly(ethylene terephthalate) assisted by supercritical carbon dioxide显示文摘The concentration of acetaldehyde(AA) is the main quality index of poly(ethylene terephthalate)(PET) used in food and drink packaging.A new method for AA removal has been developed by using supercritical carbon dioxide(sc CO2) during the solid-state polycondensation of PET.The influence factors of AA removal including the temperature,pressure,reaction time and the size of pre-polymer particles are systematically studied in this work.The results indicate that it is a highly efficient way to obtain high molecular weight PET with relative low concentration of AA.Correspondingly,the polymerization degree of PET could increase from 27.9 to 85.6 while the concentration of AA reduces from 0.229 × 10^(-6) to 0.055 × 10^(-6) under the optimal operation conditions of 230 °C,8 MPa and size of 0.30–0.45 mm.Thermodynamic performance tests show the increasing extent of PET crystallinity due to the fact that the plasticization of sc CO_2 is not obvious with extended reaction time,therefore the increasing crystallinity has no significant influence on AA removal.SEM observations reveal that the effects of sc CO_(2-) induced plasticization and swelling on PET increase significantly with the decrease of prepolymer size,and the surface of PET becomes more loose and porous in favor of the AA removal. | Zhenhao Xi Tian Liu Wei Si Fenglei Bi Zhimei Xu Ling Zhao | 2018 | Chinese Journal of Chemical Engineering2018，26，6： | 2 |
| 18 | Self-templated formation of cobalt-embedded hollow N-doped carbon spheres for efficient oxygen reduction显示文摘The slow kinetics at the cathode of oxygen reduction reaction(ORR)seriously limits the efficiencies of fuel cells and metal-air batteries.Pt,the state-of-the-art ORR electrocatalyst,suffers from high cost,low earth abundance,and poor stability.Here a self-templated strategy based on metal-organic frameworks(MOFs)is proposed for the fabrication of hollow nitrogen-doped carbon spheres that are embedded with cobalt nanoparticles(Co/HNC).The Co/HNC manifests better ORR activities,methanol tolerance,and stability than commercial Pt/C.The high ORR performance of Co/NHC can be attributed to the hollow structure which provides enlarged electrochemically active surface area,the formation of more Co-N species,and the introduction of defects.This work highlights the significance of rational engineering of MOFs for enhanced ORR activity and stability and offers new routes to the design and synthesis of high-performance electrocatalysts. | Ayaz Mahsud Jianian Chen Xiaolei Yuan Fenglei Lyu Qixuan Zhong Jinxing Chen Yadong Yin Qiao Zhang | 2021 | Nano Research2021，14，8： | 2 |
| 19 | Failure wave motion of 3D-C/SiC composites subjected to shock compression显示文摘The response and failure behavior of 3D-C/S軨 composites subjected to shock compression have been experimentally studied. With the help of a one-stage light gas gun, the 3D-C/SiC composite samples, which are subjected to the plane shock compression by LY-12 aluminum flyer sheets with different speeds become available. Based on the analysis of observation for the curve of pressure vs time, which has been measured from the tests as well as from the samples, it is found that when the shock speed is larger than a critical value, the material of 3D-C/SIC will be comminuted and the failure surface will move from the shock plane to its inward direction in the waveform. | Qingming Zhang Fenglei Huang Liming Han | 2000 | Chinese Science Bulletin2000，45，5： | 2 |
| 20 | PLASTIC BEHAVIOR AND CONSTITUTIVE MODELING OF ARMOR STEEL OVER WIDE TEMPERATURE AND STRAIN RATE RANGES显示文摘Plastic behavior of 603 armor steel is studied at strain rates ranging from 0.001 s-1 to 4500 s-1 , and temperature from 288 K to 873 K. Emphasis is placed on the effects of temperature, strain rate, and plastic strain on flow stress. Based on experimental results, the JC and the KHL models are used to simulate flow stress of this material. By comparing the model prediction and the experimental results of strain rate jump tests, the KHL model is shown to have a better prediction of plastic behavior under complex loading conditions for this material, especially in the dynamic region. | Zejian Xu Fenglei Huang | 2012 | Acta Mechanica Solida Sinica2012，25，6： | 2 |
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