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| 1 | Association of H.pylori infection with gastric carcinoma:a Meta analysis显示文摘AIM: To follow the principles of evidence based medicine to reach the integrated results of these studies.METHODS: Twenty-one papers of case-control studies were selected, including 11 on gastric cancer, 7 on precancerous lesion of stomach and 3 on lymphoma of stomach: Meta analysis was used to sum up the odds ratios (OR) of these studies.RESULTS: H. Pylori vsgastric cancer (intestinal and diffuse type): the odds ratio from the fixed effect model is 3.0016(95% Cl 2.4197-3.7234, P < 0.001 ). H. Pylori vs precancerous lesion of stomach: a random effect model was used to calculate the summary odds ratio and its value is 2.5635 (95% Cl: 1.8477-3.5566, P < 0.01). H. Pylori vs lymphoma of stomach: though the quantity of literature is too small to make Meta analysis, the data of these 3 studies show that lymphoma of stomach is highly associated with H. Pylori infections.CONCLUSION: Since it had been revealed that H. Pylori infection pre-exists in gastric carcinoma and precancerous lesions, the results of Meta analysis present a strong evidence to support the conclusion that H. Pylori infection is a risk factor for gastric carcinoma. | Fu-Bo Xue~1 Yong-Yong Xu~1 Yi Wan~1 Bo-Rong Pan~2 Jun Ren~2 Dai-Ming Fan~3 1 Department of Health Statistics,Department of2 Oncology3 Gastroenterology of XiJing Hospital,the Fourth Military Medical University,Xi’an 710032,Shaanxi Province,China | 2001 | World Journal of Gastroenterology2001，7，6： | 66 |
| 2 | Interannual variability of Antarctic Oscillation and its influence on East Asian climate during boreal winter and spring显示文摘The interannual variability of Antarctic Oscillation (AAO) and its influence on East Asian climate during both boreal winter and spring are addressed. The results show that the positive AAO anomaly decreases the cold activity over East Asia during both boreal winter and spring. AAO-related barotropic meridional teleconnection from Antarctic to Arctic is found through analysis of mean me- ridional circulations. This meridional teleconnection is remarkable over Eurasia during boreal winter and over the Pacific Ocean during boreal spring. The results also show that zonal mean zonal wind at high latitudes in Southern Hemisphere has well positive correlation with that of Eurasia during boreal winter and has negative correlation with Pacific North American teleconnection (PNA) during boreal spring, which again display the meridional teleconnection. Thus, local meridional teleconnection is a possible linkage for interaction of circulations at mid-high latitudes between both hemispheres. | FAN Ke1,2,3 & WANG Huijun2 1. Nansen-Zhu International Research Center, Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing 100029, China 2. Department of Atmospheric Science, Yunnan University, Kunming 650091, China 3. Graduate University of the Chinese Academy of Sciences, Beijing 100049, China | 2006 | Science China Earth Sciences2006，49，5： | 36 |
| 3 | Antisense to cyclin D1 reverses the transformed phenotype of human gastric cancer cells显示文摘INTRODUCTIONStudiesonthefunctionsofcelularprotooncogenesandtumorsuppresorgenesindicatethatmostofthesegenesmediatesignaltrans... | CHEN Bing 1, ZHANG Xue Yong 2, ZHANG Yu Jing 3, ZHOU Ping 3, GU Yan 4 and FAN Dai Ming 2 | 1999 | World Journal of Gastroenterology1999，5，1： | 23 |
| 4 | Forecasting the summer rainfall in North China using the year-to-year increment approach显示文摘A new approach to forecasting the year-to-year increment of rainfall in North China in July-August (JA) is proposed. DY is defined as the difference of a variable between the current year and the preceding year (year-to-year increment). NR denotes the seasonal mean precipitation rate over North China in JA. After analyzing the atmospheric circulation anomalies associated with the DY of NR, five key predictors for the DY of NR have been identified. The prediction model for the DY of NR is established by using multi-linear regression method and the NR is obtained (the current forecasted DY of NR added to the preceding observed NR). The prediction model shows a high correlation coefficient (0.8) between the simulated and the observed DY of NR throughout period 1965-1999, with an average relative root mean square error of 19% for the percentage of precipitation rate anomaly over North China. The prediction model makes a hindcast for 2000-2007, with an average relative root mean square error of 21% for the percentage of precipitation rate anomaly over North China. The model reproduces the downward trend of the percentage of precipitation rate anomaly over North China during 1965-2006. Because the current operational prediction models of the summer precipitation have average forecast scores of 60%-70%, it has been more difficult to forecast the summer rainfall over North China. Thus this new approach for predicting the year-to-year increment of the summer precipitation (and hence the summer precipitation itself) has the potential to significantly improve operational forecasting skill for summer precipitation. | FAN Ke1, LIN MeiJing1,2 & GAO YuZhong3 1 Nansen-Zhu International Research Center, Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing 100029, China 2 Graduate University of the Chinese Academy of Sciences, Beijing 100049, China 3 Heilongjiang Meteorological Administration, Harbin 150030, China | 2009 | Science China Earth Sciences2009，52，4： | 18 |
| 5 | Hierarchy modeling of subsurface palaeochannel reservoir architecture显示文摘The studies on fluvial reservoir architecture are mainly aimed at outcrop and modern deposition,but rarely at the subsurface reservoir,so there are few effective methods to predict the distribution of subsurface reservoir architectures. In this paper,taking the meandering river reservoir of Guantao formation Gudao Oilfield,Jiyang depression,Baohai Gulf Basin,East China as an example,the archi-tectural modeling method of complex meandering belt reservoir is proposed,that is hierarchy con-straint,pattern fitting and multi-dimensional interaction. Architectures of meandering river reservoir can be divided into three hierarchies: meandering channel sandbody,point bar and lateral accretion body. Different hierarchies of the quantitative architecture pattern are fitted to subsurface well data (including dynamic monitoring data) in different hierarchies through one-dimensional hole,2D profiles and plane and 3D space,which are verified by each other. And then 3D model in different hierarchies is established. At the same time,the quantificational relationship between width of active river and the scale of point bar is set up,and the scale of lateral accretion sand body and shale beddings is con-firmed with horizontal well data. The study not only has significant meaning on the development of geology,but also can improve the oilfield exploitation greatly. | WU ShengHe1,YUE DaLi1,LIU JianMin2,SHU QingLin2,FAN Zheng1,3 & LI YuPeng1 1 Earth Sciences and Geoinformatics School,China University of Petroleum,Beijing 102249,China 2 SINOPEC Shengli Oilfield Co. Ltd.,Dongying 257000,China 3 Beijing Telon High-tech Corporation,Beijing 100085,China | 2008 | Science China Earth Sciences2008，51，S2： | 15 |
| 6 | Ectopic expression of a hyacinth AGL6 homolog caused earlier flowering and homeotic conversion in Arabidopsis显示文摘MADS-box genes are involved in floral organ development. Here we report that an AGL6(Agamous-like 6)-like MADS-box gene, HoAGL6, was isolated from Hyacinthus orientalis L. Expression pattern analy-sis demonstrated that HoAGL6 transcript was detected in inflorescence buds, tepals, carpels and ovules, but not in stamina, leaves or scales. Transgenic Arabidopsis plants ectopically expressing HoAGL6 exhibited novel phenotypes of significantly reduced plant size, extremely early flowering, and losing inflorescence indeterminacy. In addition, wide homeotic conversion of sepals, petals, and leaves into carpel-like or ovary structures, and disappearance or number reduction of stamens in 35S::HoAGL6 Arabidopsis plants were also observed. RT-PCR analysis indicated that the expressions of flowering time gene SOC1 and flower meristem identity gene LFY were significantly up-regulated in 35S::HoAGL6 transgenic Arabidopsis plants, and the expression levels of floral organ identity genes AG and SEP1 in leaves were also elevated. These results indicated that HoAGL6 was involved in the regulation of flower transition and flower organ formation. | FAN JinHui1, LI WenQing2, DONG XiuChun1, GUO Wei1 & SHU HuaiRui3 1 College of Forestry, Shandong Agricultural University, Taian 271018, China 2 College of Biological Science, China Agricultural University, Beijing 100094, China 3 College of Horticulture Science and Engineering, Shandong Agricultural University, Taian 271018, China | 2007 | Science China(Life Sciences)2007，50，5： | 12 |
| 7 | Genome size and sequence composition of moso bamboo: A comparative study显示文摘Moso bamboo (Phyllostachys pubescens) is one of the world's most important bamboo species. It has the largest area of all planted bamboo―over two-thirds of the total bamboo forest area―and the highest economic value in China. Moso bamboo is a tetraploid (4x=48) and a special member of the grasses family. Although several genomes have been sequenced or are being sequenced in the grasses family, we know little about the genome of the bambusoids (bamboos). In this study, the moso bamboo genome size was estimated to be about 2034 Mb by flow cytometry (FCM), using maize (cv. B73) and rice (cv. Nipponbare) as internal references. The rice genome has been sequenced and the maize genome is being sequenced. We found that the size of the moso bamboo genome was similar to that of maize but significantly larger than that of rice. To determine whether the bamboo genome had a high proportion of repeat elements, similar to that of the maize genome, approximately 1000 genome survey sequences (GSS) were generated. Sequence analysis showed that the proportion of repeat elements was 23.3% for the bamboo genome, which is significantly lower than that of the maize ge-nome (65.7%). The bamboo repeat elements were mainly Gypsy/DIRS1 and Ty1/Copia LTR retrotrans-posons (14.7%), with a few DNA transposons. However, more genomic sequences are needed to con-firm the above results due to several factors, such as the limitation of our GSS data. This study is the first to investigate sequence composition of the bamboo genome. Our results are valuable for future genome research of moso and other bamboos. | GUI YiJie1, WANG Sheng1, QUAN LiYan1, ZHOU ChangPing2, LONG ShiBao2, ZHENG HuaJun3, JIN Liang1, ZHANG XianYin 1, MA NaiXun 4 & FAN LongJiang1 1 Institute of Crop Science/Institute of Bioinformatics, Zhejiang University, Hangzhou 310029, China 2 Zhejiang Anji Bamboo Exposition Garden, Anji 313300, China 3 Chinese National Human Genome Center at Shanghai, Shanghai 201203, China 4 The Research Institute of Subtropical Forestry, Chinese Academy of Forestry, Fuyang 311400, China | 2007 | Science China(Life Sciences)2007，50，5： | 10 |
| 8 | Proteomic analysis of mitochondria reveals a metabolic switch from fatty acid oxidation to glycolysis in the failing heart显示文摘This work characterizes the mitochondrial proteomic profile in the failing heart and elucidates the molecular basis of mitochondria in heart failure. Heart failure was induced in rats by myocardial infarction, and mitochondria were isolated from hearts by differential centrifugation. Using two-dimensional gel electrophoresis and matrix-assisted laser desorption/ionization-time of flight mass spectrometry, a system biology approach was employed to investigate differences in mitochondrial proteins between normal and failing hearts. Mass spectrometry identified 27 proteins differentially expressed that involved in energy metabolism. Among those, the up-regulated proteins included tricarboxylic acid cycle enzymes and pyruvate dehydrogenase complex subunits while the down-regulated proteins were involved in fatty acid oxidation and the OXPHOS complex. These results suggest a substantial metabolic switch from free fatty acid oxidation to glycolysis in heart failure and provide molecular evidence for alterations in the structural and functional parameters of mitochondria that may contribute to cardiac dysfunction during ischemic injury. | WANG Jun1,2, BAI Ling1,2, LI Jing3, SUN ChaoFeng1,2, ZHAO Jin1, CUI ChangCong1,2, HAN Ke1,2, LIU Yu1,2, ZHUO XiaoZhen1,2, WANG TingZhong1,2, LIU Ping1,2, FAN FenLing1,2, GUAN YouFei3 & MA AiQun1,2 1 Department of Cardiology, First affiliated hospital of medical college of Xi’an Jiaotong University, Xi’an 710061, China 2 Ion Channel Disease Laboratory, Key Laboratory of Environment and Genes Related to Diseases of Education Ministry, Xi’an 710061, China 3 Department of Physiology and Pathophysiology Key Laboratory of Molecular Cardiovascular Sciences of the Ministry of Education, Peking University Health Science Center, Beijing 100083, China | 2009 | Science China(Life Sciences)2009，52，11： | 10 |
| 9 | Suppression of Type 1 Insulin-like Growth Factor Receptor Expression by Small Interfering RNA Inhibits A549 Human Lung Cancer Cell Invasion in vitro and Metastasis in Xenograft Nude Mice显示文摘癌症侵略和转移,包含许多病理学的过程和 cytophysiological 变化,贡献肺癌症的高死亡。类型 1insulin-like 生长因素受体(IGF-1R ) ,把前进和侵略与癌症联系了,是在肺癌症的一个潜在的反侵略和反转移目标。禁止肺癌症房间的侵略性质,我们在由小介入 RNA ( siRNA )技术的 A549 人的肺癌症房间的成功地下面调整的 IGF-1R 基因表达,并且评估了它的效果oninvasion相关的基因表达,在 vitro 侵略的肿瘤房间,并且在有为 IGF-1R 表示发卡 siRNA 的一个原生质标志的异种皮移植 nudemice.A549 房间 transfected 的转移在 mRNA 水平以及蛋白质 level.Inbiological 试金显示出一个显著地减少的 IGF-1R 表达式, transfected A549 房间显示出 cell-matrixadhesion ,移植和侵略的重要减小。与这些结果一致,我们发现那条下面规定大减小附随地在侵略相关的基因表达伴随的 ofIGR-1R , includingMMP-2 , MMP-9 , u-PA ,并且为 IGF-1R 的 plasmidexpressing 发卡 siRNA 的 IGF-1R 特定的下游的 p-Akt.Direct 尾巴静脉注射显著地在结果显示出的 nudemice.Our 禁止了肺转移的形成是的 siRNA 的治疗学的潜力为在禁止肺癌症侵略和转移的基因治疗的一个方法。 | Jianfang QIAN~1 Aiqiang DONG~1 Minjian KONG~1 Zhiyuan MA~2 Junqiang FAN~1 and Guanyu JIANG~3 ~1Department of Cardiothoracic Surgery,Second Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou 310009,China ~2Department of Cardiovascular Surgery,Shanghai Jiaotong University Affiliated First People’s Hospital,Shanghai 200080,China ~3Department of Emergency,Second Affiliated Hospital School of Medicine,Zhejiang University,Hangzhou 310009,China | 2007 | Acta Biochimica et Biophysica Sinica2007，39，2： | 9 |
| 10 | STAT1 Antisense Oligonucleotides Attenuate the Proinflammatory Cytokine Release of Alveolar Macrophages in Bleomycin-Induced Fibrosis显示文摘To investigate the effect of signal transducers and activators of transcription 1 (STAT1) antisense oligonucleotides (ASON) on concentrations of TNF-α, IL-8, NO secreted by alveolar macrophages (AMs) in bleomycin-induced rat pulmonary fibrosis, five adult female Wistar rats were intratracheally instilled with bleomycin. After 7 days, the rats were killed by right ventricle of heart exsanguinations under ketamine anaesthesia and bronchoalveolar lavage (BAL) was performed to obtain AMs. AMs were divided into four groups, treated with STAT1 ASON, STAT1 sense oligonucleotides (SON), dexamethasone (DEX) and medium alone (control), respectively. AMs and media were collected after culture for 36 h. The mRNA and protein expressions of STAT1 and ICAM-1 in AMs were detected by RT-PCR and ELISA, respectively. The concentrations of TNF-α, IL-8, NO in cultured medium were detected.The STAT1 mRNA expression by AMs in the STAT1 ASON group was lower than those of AMs in the STAT1 SON group, the DEX group and the control group (p < 0.05). Moreover, the STAT1 mRNA expression by AMs in the DEX group was also lower than those of AMs in the STAT1 SON group and the control group (p < 0.05), but the STAT1 mRNA expression by AMs in the STAT1 SON group was not different from that of the control group (p >0.05). The protein expressions of STAT1 and ICAM-1 and the mRNA expression of ICAM-1 showed similar changes to the STAT1 mRNA expression by AMs. The concentrations of TNF-α, IL-8, NO in cultured medium from STAT1 ASON group were lower than those from STAT1 SON, DEX and the control groups (p < 0.05). Moreover,the concentrations of TNF-α, IL-8, NO in cultured medium from DEX group were also lower than those from the control and STAT1 SON group (p < 0.05), but no difference between STAT1 SON group and the control (p > 0.05).The results suggest that STAT1 ASON could inhibit the secretion of TNF-α, IL-8, NO in AMs, and STAT1 could become a target of treating pulmonary fibrosis. | Xianming Fan~(1,3) Zengli Wang~2 ~1Department of Respiratory Medicine,the Affiliated Hospital of Luzhou Medical College,Luzhou 646000,China ~2Department of Respiratory Medicine,West China Hospital,Sichuan University,Chengdu 610041,China ~3Corresponding to:Dr.Xianming Fan,Department of Respiratory Medicine,the Affiliated Hospital of Luzhou Medical College,Luzhou 646000,China. | 2005 | Cellular & Molecular Immunology2005，2，3： | 8 |
| 11 | Overexpression of hepatic plasminogen activator inhibitor type 1 mRNA in rabbits with fatty liver显示文摘INTRODUCTIONPlasminogen activator inhibitor type 1 ( PAI-I ), an approximately Mr 50000 glycoprotein, is the major physiological inhibitor of plasminogen activators. It is not only the priming factor for atherosclerosis and coronary thrombosis[1-3] , but also participates in the genesis of chronic hepatitis and liver fibrosis[4-11] . However, there has been no available report yet about the research of hepatic PAl-1 gene expression in hyperlipidemia and fatty liver. The present study aimed to explore the change of hepatic PAl-1 mRNA and its plasma activity by means of animal model. | Jian-Gao Fan~1 Liang-Hua Chen~2 Zheng-Jie Xu~1 Min-De Zeng~3 1 Department of Gastroenterology,Shanghai First People’s Hospital,Shanghai 200085,China2 Department of Cardiology,Shandong Provincial Hospital,Jinan 250021,China3 Shanghai Institute of Digestive Diseases,Shanghai 200080,China | 2001 | World Journal of Gastroenterology2001，7，5： | 8 |
| 12 | Hydrodynamics of a Newly China-Made Jiuling Bileaflet Heart Valve Prostheses显示文摘Jiuling bileaflet prosthetic heart valve is manufactured in compliance with the national standard of P.R.C. GB12279 90. This mechanical heart valve substitute is constructed entirely of solid low temperature pyrolytic carbon. There is no graphite substrate within the leaflets or orifice. This prosthesis presents with satisfactory histocompatibility and induces little hemocoagulation around it. Objective: This study aimed to assess the hydrodynamic function of the newly China made Jiuling bileaflet heart valve prostheses. Methods: Jiuling valve has been tested in a pulsatile flow simulator in the aortic position. The testing condition was set at the pulsatile frequency of 55, 75, and 100 beats/min and a constant cardiac output of 4 L/min. The mean pressure differences, leakage volumes and closing volumes across each valve, and the effective orifice areas have been analyzed. Results: The Jiuling heart valves prosthesis had the lowest pressure difference at any given tissue annulus diameter. The mean pressure difference of all the Jiuling valves decreases with increasing the tissue annulus diameter or pulse frequency, and is in the range of below 10 mmHg. CarboMedics (CarboMedics, Inc., Austin, Tex.) is similar to that of the 21 mm and 23 mm Jiuling heart valves at the given pulse rate under 4 L/min. C L tilting disc valve (Lanzhou CarboMedics Inc., China) is similar to that of the 23 mm Jiuling heart valve. The effective orifice area of the Jiuling mechanical valve increases with increasing the tissue annulus diameter or pulse frequency. CarboMedics and C L tilting disc valve is similar to that of the 21 mm and 23 mm Jiuling heart valves. The Closing volume of the Jiuling prosthetic cardiac valves increases with increasing the tissue annulus diameter, but decreases with increasing the pulse frequency, and is in the range of below 11% (normalized by stroke volume). CarboMedics is below 16.5% of stroke volume; and C L tilting disc valve is below 7.5%. The leakage volume of the Jiuling prosthetic cardiac valves increases with increasing the tissue annulus diameter, but decreases with increasing the pulse frequency, and are in the range of below 28.9% (normalized by stroke volume). The leakage volume of CarboMedics is higher than that of the same sized 25 mm Jiuling valve, and the C L tilting disc valve is also higher than that of Jiuling valve at 4 L/min. Conclusion: For a given tissue diameter, the Jiuling valve showed significantly better hemodynamic characteristics. The material used in the construction is biocompatible, durable, and thromboresistant. The design permits light weight, low profile, and high ratio of flow area to tissue annulus diameter. | CHU Yin ping 1,CHEN Ru kun 2,FAN Yu bo 3 , PU Fang 31 Department of Thoracic & Cardiovascular Surgery Second Hospital Affiliated Shanxi Medical University, Taiyuan 030001,China 2 Second Affiliated Hospital of Zhejiang University Medical | 2000 | Chinese Journal of Biomedical Engineering(English Edition)2000，9，4： | 8 |
| 13 | A Method for the Environmental Quality Assessment of Surface Water Based on Artificial Neural Networks | YANG Guo\|dong\+1,\ PAN Da\|feng\+2,\ FAN Ying\|fang\+3 1.Dep. of Environmental Science, Shanxi Uni., Taiyuan 030006, China 2.Shanxi Academy of Agriculture Science, Taiyuan 030031, China 3.Institute of Molecular Science, Shanxi Uni., Taiyuan 030006, C | 2000 | Systems Science and Systems Engineering2000，10，1： | 7 |
| 14 | The central black hole masses for the γ-ray loud blazars显示文摘The Large Area Telescope (LAT) on the Fermi Gamma-ray Space Telescope (formerly GLAST) provides an increase in sensitivity and has detected rapid variability of gamma-ray sources.The variability time scales detected from the gamma-ray loud blazars by LAT and EGRET,and gamma-ray luminosity are used to estimate the central black hole masses.In this work,we find that the lower limits of central black hole masses are in a range of (0.3-24)×107M⊙,which are compared with those obtained by other authors.Our results are consistent with other authors' results.Also,the Lorentz factor,Γ,and the propagation angle,θ,are obtained for 18 blazars for which superluminal motions are known. | YANG JiangHe1,2* & FAN JunHui2,3 1 Department of Physics and Electronics Science,Hunan University of Arts and Science,Changde 415000,China 2 Center for Astrophysics,Guangzhou University,Guangzhou 510405,China 3 Key Laboratory of Astronomy Observation and Technology,Guangzhou University,Guangzhou 510405,China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，10： | 6 |
| 15 | Isotope Method for Confined Groundwater Recharge of the Lower Reaches of the Heihe River,Inner Mongolia,China显示文摘环境同位素被使用了分析限制地下水在 Heihe 河的更低的活动范围再装,内部蒙古。CFC 被认为是决定地下水的日期的示踪物,是的日期不到 45 一。在除 Heihe 河力量的表水以外的 Gurinai 区域和 Ejin 盆以内的限制地下水从 Qilian 山或 / 并且西藏的高原从降水发源。深限制的地下水溢出进上面的含水土层并且出现进地面,形成在内的弹簧和湖 thelow 躺区域。recharge 体积被估计在 400 百万立方的米附近。 | CHEN Jiansheng ZHAO Xia FAN Zhechao and WANG Jiyang 1 State Key Laboratory of Hydrology-Water Resources and Hydraulic Engineering,Hohai University,Nanjing 210098,China 2 Institute of Isotope Hydrology Research,Hohai University,Nanjing 210098,China 3 Institute of Geology and Geophysics,Chinese Academy of Science,Beijing 100018,China | 2007 | Acta Geologica Sinica(English Edition)2007，81，4： | 5 |
| 16 | The line emissions and polarization in blazars显示文摘The correlations between broad-line emission,polarization,and core-dominance parameters are investigated for a sample of 148 blazars(BL Lacertae objects-BLs and flat spectrum radio quasars-FSRQs). An anti-correlation between the broad-line luminosity and the linear polarization is found. The broad-line and polarization relation can be explained by using a relativistic beaming model,which perhaps suggests that BL Lacs and FSRQs are a single class. We also investigated the relation between the ratio of the broad-line luminosity to the Eddington luminosity and linear polarization,and that between the ratio of the broad-line luminosity to the Eddington luminosity and the core-dominance parameter. | YANG JiangHe 1,2 ,FAN JunHui 2,3 & YANG RuShu 1 1 Department of Physics and Electronics Science,Hunan University of Arts and Science,Changde 415000,China 2 Center for Astrophysics,Guangzhou University,Guangzhou 510405,China 3 Key Laboratory of Astronomy Observation and Technology,Guangzhou University,Guangzhou 510405,China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，6： | 4 |
| 17 | Investigation of integrons/cassettes in antimicrobial-resistant Escherichia coli isolated from food animals in China显示文摘In this study,326 Escherichia coli isolates from food animals collected during the last four decades in China were characterized using antimicrobial susceptibility testing and screening for integrons/cassettes.Minimum inhibitory concentration(MIC) testing indicated that the antimicrobial resistance of E.coli has increased since the 1970s.The findings of this study present a warning to veterinary practitioners about the excessive use of antimicrobials,and suggest the necessity for surveillance and control of antimicrobial resistance in veterinary clinical medicine in China. | SONG Li1,NING YiBao1,SHEN JianZhong2,FAN XueZheng,ZHANG ChunPing1,YANG ChengHuai1 & HAN JianFeng3 1 China Institute of Veterinary Drug Control,Beijing 100081,China 2 China Agricultural University,Beijing 100094,China 3 China Center for Disease Control and Prevention,Beijing 100050,China | 2010 | Science China(Life Sciences)2010，53，5： | 3 |
| 18 | Indeterminacy-aware service selection for reliable service composition显示文摘 | Xiaoqin Fan (1) fxq0917@hotmail.com Xianwen Fang (2) Zhijun Ding (3) | 2011 | Frontiers of Computer Science2011，5，1： | 3 |
| 19 | Gaining effciency via weighted estimators for multivariate failure time data显示文摘Multivariate failure time data arise frequently in survival analysis.A commonly used tech-nique is the working independence estimator for marginal hazard models.Two natural questions are how to improve the effciency of the working independence estimator and how to identify the situations under which such an estimator has high statistical effciency.In this paper,three weighted estimators are proposed based on three different optimal criteria in terms of the asymptotic covariance of weighted estimators.Simplifiedclose-form solutions are found,which always outperform the working indepen-dence estimator.We also prove that the working independence estimator has high statistical effciency,when asymptotic covariance of derivatives of partial log-likelihood functions is nearly exchangeable or diagonal.Simulations are conducted to compare the performance of the weighted estimator and work-ing independence estimator.A data set from Busselton population health surveys is analyzed using the proposed estimators. | FAN JianQing1,2,ZHOU Yong2,3,CAI JianWen4 & CHEN Min3 1 Department of Operations Research and Financial Engineering,Princeton University,Princeton,NJ08544,USA 2 Department of Statistics,Shanghai University of Finance and Economics,Shanghai 200433,China 3 Institute of Applied Mathematics,Academy of Mathematics and Systems Science,Chinese Academy of Sci-ences,Beijing 100190,China 4 Department of Biostatistics,University of North Carolina at Chapel Hill,Chapel Hill,NC 27599-7420,USA | 2009 | Science China Mathematics2009，52，6： | 2 |
| 20 | s-ordering operator expansions of quantum-mechanical fundamental representations and their applications显示文摘We show that the quantum-mechanical fundamental representations, say, the coordinate representation, the coherent state representation, the Fan-Klauder entangled state representation can be recast into s-ordering operator expansion, which is elegant in form and has many applications in deriving new operator identities. This demonstrates that Dirac's symbolic method can be merged into Newton-Leibniz integration theory in a broad way. | FAN HongYi 1,3 , XU YeJun 2 & YUAN HongChun 3,4 1 Department of Materials Science and Engineering, University of Science and Technology of China, Hefei 230026, China 2 Department of Physics Electronic and Engineering, Chizhou University, Chizhou 247000, China 3 Department of Physics, Shanghai Jiao Tong University, Shanghai 200030, China 4 College of Optoelectronic Engineering, Changzhou Institute of Technology, Changzhou 213002, China | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，12： | 2 |
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