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| 1 | Next generation sequencing in cardiovascular diseases显示文摘In the last few years,the advent of next generation sequencing(NGS) has revolutionized the approach to genetic studies,making whole-genome sequencing a possible way of obtaining global genomic information.NGS has very recently been shown to be successful in identifying novel causative mutations of rare or common Mendelian disorders.At the present time,it is expected that NGS will be increasingly important in the study of inherited and complex cardiovascular diseases(CVDs).However,the NGS approach to the genetics of CVDs represents a territory which has not been widely investigated.The identification of rare and frequent genetic variants can be very important in clinical practice to detect pathogenic mutations or to establish a profile of risk for the development of pathology.The purpose of this paper is to discuss the recent application of NGS in the study of several CVDs such as inherited cardiomyopathies,channelopathies,coronary artery disease and aortic aneurysm.We also discuss the future utility and challenges related to NGS in studying the genetic basis of CVDs in order to improve diagnosis,prevention,and treatment. | Francesca Faita Cecilia Vecoli Ilenia Foffa Maria Grazia Andreassi | 2012 | World Journal of Cardiology2012，4，10： | 2 |
| 2 | Solid supported chiral auxiliaries in asymmrtric synthesis (Part 2): catalysis of 1,3-dipolar cycloadditions by Mg(Ⅱ) cation显示文摘 | Faita G Paio A Quadrelli P | 2001 | Tetrahedron2001，57，： | 1 |
| 3 | In search of exo - selective catalysts for enantioselective 1,3 - dipolar cycloaddition between acryloyloxazolidinone and diphenylnitrone 显示文摘 | Desimoni G Faita G Mella M | 2005 | Eur J Org Chem2005，6，： | 1 |
| 4 | Arsenic-induced genotoxicity and genetic susceptibility to arsenic-related pathologies 显示文摘 | Faita F Cori L Bianchi F | 2013 | Int J Environ Res Public Health2013，10，4： | 1 |
| 5 | Real-Time Measurement System for Evaluation of the Carotid Intima-Media Thickness with a Robust Edge Operator显示文摘 | Faita F Gemignani V Bianchini E | 2008 | Journal of Ultrasound in Medicine2008，27，9： | 1 |
| 6 | Relationship between wave reflection and renal damage in hypertensive patients: a retrospective analysis 显示文摘 | Stea F Sqro M Faita F | 2013 | J hypertens2013，31，12： | 1 |
| 7 | GABA shunt deftcieneies and accumulation of reactive oxygen inter-mediates:insight from Arabidopsis mutants显示文摘 | Faita A Yellinb A and Frommb H | 2005 | FFBS Letters2005，579，： | 1 |
| 8 | An event -related potential (ERP) study of musical expectancy: comparison of musicians with nonmusicians 显示文摘 | Besson M Faita F | 1995 | Journal of Experimental Psychol- ogy: Hum Perception and Performance1995，，21： | 1 |
| 9 | C2-Symmetric chiral bis (oxazoline) ligands in asymmetric catalysis 显示文摘 | Desimoni G Faita G Jorgensen K A | 2011 | Chem Rev2011，111，： | 1 |
| 10 | Deactivation mechanisms of oxygen evolving anodes at high current densities 显示文摘 | MARTELLI G N ORNELAS R FAITA G | 1994 | Electrochimica Acta1994，39，1112： | 1 |
| 11 | A soluble polymer-bound Evans' chiral auxiliary: synthesis, characterization and use in cycloaddition reactions 显示文摘 | DESIMONI D FAITA G GALBIATI A | 2002 | Tetrahedron :Asymmetry2002，13，4： | 1 |
| 12 | GABA shunt deficiencies and accumulation of reactive oxygen inter-mediates:insight from Arabidopsis mutants显示文摘 | FAITA A YELLINB A FROMMB H | 2005 | Febs Letters2005，579，： | 1 |
| 13 | Solid supported chiral auxiliaries in asymmetric synthesis (part 2):catalysis of 1,3-dipolar cycloadditions by Mg(Ⅱ) cation显示文摘 | Faita G Paio A Quadrelli P | 2001 | Tetrahedron2001，57，： | 1 |
| 14 | Solid supported chiral auxiliaries in asymmetric synthesis显示文摘 | Faita G Paio A Quadrelli P | 2001 | Tetrahedron2001，57，： | 1 |
| 15 | Solid supported chiral auciliaries in asymmetric synthesis(Part 2) ;Catalysis of 1,3-dipolar eyeloadditions by Mg( Ⅱ ) cation 显示文摘 | Faita G Paio A Quadrelli P | 2001 | Tetrahedron2001，57，39： | 1 |
| 16 | A soluble polymer-bound Evans chiral auxiliary:synthesis,characterization and use cycoaddition reactions显示文摘 | Desimoni G Faita G Galbiati A | 2002 | Tetrahedron:Asymmetry2002，13，： | 1 |
| 17 | Asymmetric Friedel - Crafts alkylation of activated benzenes with methyl ( E ) - 2 - oxo - 4 - aryl - 3 - butenoates catalyzed by 显示文摘 | Faita G Mella M Toscanini M | 2010 | Tetrahedron2010，66，16： | 1 |
| 18 | 显示文摘 | Martelli G Omelas R Faita G | 1994 | Electrochimica Acta1994，39，1112： | 1 |
| 19 | Pyridine-2,6-bis(oxazolines),Helpful Ligands for Asymmetric Catalysts显示文摘 | Desimoni G Faita G Quadrelli P | 2003 | Chem Rev2003，103，： | 1 |
| 20 | Can a Chiral Catalyst Containing the Same Ligand/metal Components Promote the Formation of Both Enantiomers Enantioselectively The Bis(oxazoline)-magnesium Perchlorate-catalyzed Asymmetric Diels-Alder Reaction显示文摘 | DESIMONI G FAITA G INVERNIZZI A G | 1997 | Tetrahedron1997，53，22： | 1 |
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