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| 1 | An efficient enhanced k-means clustering algorithm显示文摘In k-means clustering, we are given a set of n data points in d-dimensional space úd and an integer k and the problem is to determine a set of k points in úd, called centers, so as to minimize the mean squared distance from each data point to its nearest center. In this paper, we present a simple and efficient clustering algorithm based on the k-means algorithm, which we call en- hanced k-means algorithm. This algorithm is easy to implement, requiring a simple data structure to keep some information in each iteration to be used in the next iteration. Our experimental results demonstrated that our scheme can improve the computational speed of the k-means algorithm by the magnitude in the total number of distance calculations and the overall time of computation. | FAHIM A.M SALEM A.M TORKEY F.A RAMADAN M.A | 2006 | Journal of Zhejiang University-Science A(Applied Physics & Engineering)2006，7，10： | 28 |
| 2 | Preliminary experience with drug-coated balloon angioplasty in primary percutaneous coronary intervention显示文摘We evaluated the clinical feasibility of using drugcoated balloon(DCB) angioplasty in patients undergoingprimary percutaneous coronary intervention(PPCI). Between January 2010 to September 2014,89 STelevation myocardial infarction patients(83% male,mean age 59 ± 14 years) with a total of 89 coronary lesions were treated with DCB during PPCI. Clinical outcomes are reported at 30 d follow-up. Left anterior descending artery was the most common target vessel for PCI(37%). Twenty-eight percent of the patients had underlying diabetes mellitus. Mean left ventricular ejection fraction was 44% ± 11%. DCB-only PCI was the predominant approach(96%) with the remaining 4% of patients receiving bail-out stenting. Thrombolysis in Myocardial Infarction(TIMI) 3 flow was successfully restored in 98% of patients. An average of 1.2 ± 0.5 DCB were used per patient,with mean DCB diameter of 2.6 ± 0.5 mm and average length of 23.2 ± 10.2 mm. At 30-d follow-up,there were 4 deaths(4.5%). No patients experienced abrupt closure of the infarctrelated artery and there was no reported target-lesion failure. Our preliminary experience showed that DCB angioplasty in PPCI was feasible and associated with a high rate of TIMI 3 flow and low 30-d ischaemic event. | Hee Hwa Ho Julian Tan Yau Wei Ooi Kwok Kong Loh Than Htike Aung Nwe Tun Yin Dasdo Antonius Sinaga Fahim Haider Jafary Paul Jau Lueng Ong | 2015 | World Journal of Cardiology2015，7，6： | 14 |
| 3 | Mechanisms of action of leptin in preventing gastric ulcer显示文摘AIM: To investigate the effects of leptin (1-20 μg/kg) on acidified ethanol (AE)- and indomethacin (Indo)-induced gastric lesions in rats and compare it with ranitidine, lansoprazole, and omeprazole and to determine its mechanisms of actions.METHODS: Gastric ulcers, which were approximately 1 mm in width, formed in the glandular portion of the gastric mucosa produced by oral administration of either AE or Indo were taken as ulcer index. The inhibitory effect of subcutaneous administration of leptin, two proton pump inhibitors (PPIs) lansoprazole and omeprazole, or H2-receptor antagonist ranitidine 30 min before AE or Indo was evaluated.A radioimmunoassay was used to determine the PGE2concentration in the homogenate of the glandular portion of the stomach. We performed histological study of the glandular stomach for the evaluation of total, acidic, and sulfated mucus content.RESULTS: Subcutaneous administration of leptin, two PPIs lansoprazole and omeprazole or H2-receptor antagonist ranitidine 30 min before AE or Indo produced a dosedependent and reproducible inhibition of gastric ulcers (GUs). This inhibition was found to be more potent than other antagonists used. In NG-nitro L-arginine methyl ester (L-NAME)-pretreated animals, the ulcer prevention ability of leptin in AE-induced ulcer was significantly reduced,compared to rats without L-NAME pretreatment. However,the ulcer prevention ability of leptin was not altered by L-NAME treatment in Indo-induced ulcers. Leptin produced a dose-dependent increase in PGE2 level in the gastric glandular tissues. Leptin also increased mucus secretion.CONCLUSION: The results of the present study show that leptin inhibits GU formation by AE or Indo in a dosedependent and reproducible manner in rats. The results also suggest that leptin prevents ulcer formation by increasing the activities of the cyclo-oxygenase and/or nitric oxide pathways and by increasing mucus secretion. | Edward O.Adeyemi Salim A.Bastaki Irwin S.Chandranath Mohammed Y.Hasan Mohammed Fahim Abdu Adem | 2005 | World Journal of Gastroenterology2005，11，27： | 9 |
| 4 | Ghrelin attenuates gastrointestinal epithelial damage induced by doxorubicin显示文摘AIM:To examine the influence of ghrelin on the regenerative potential of gastrointestinal(GI)epithelium.METHODS:Damage to GI epithelium was induced in mice by two intravenous injections of doxorubicin(10 and 6 mg/kg).Some of the doxorubicin-treated mice received a continuous subcutaneous infusion of ghrelin(1.25μg/h)for 10 d via implanted mini-osmotic pumps.To label dividing stem cells in the S-phase of the cell cycle,all mice received a single intraperitoneal injection of 5'-bromo-2'-deoxyuridine(BrdU)one hour before sacrifice.The stomach along with the duodenum were then removed and processed for histological examination and immunohistochemistry using anti-BrdU antibody.RESULTS:The results showed dramatic damage to the GI epithelium 3 d after administration of chemotherapy which began to recover by day 10.In ghrelintreated mice,attenuation of GI mucosal damage was evident in the tissues examined postchemotherapy.Immunohistochemical analysis showed an increase in the number of BrdUlabeled cells and an alteration in their distribution along the epithelial lining in response to damage by doxorubicin.In mice treated with both doxorubicin and ghrelin,the number of BrdUlabeled cells was reduced when compared with mice treated with doxorubicin alone.CONCLUSION:The present study suggests that ghrelin enhances the regenerative potential of the GI epithelium in doxorubicintreated mice,at least in part,by modulating cell proliferation. | Mohamed A Fahim Hazem Kataya Rkia El-Kharrag Dena AM Amer Basel al-Ramadi Sherif M Karam | 2011 | World Journal of Gastroenterology2011，17，33： | 3 |
| 5 | Investigating the impact of Glyoxal retrieval from MAX-DOAS observations during haze and non-haze conditions in Beijing显示文摘This study presents the Multi Axis Differential Optical Absorption Spectroscopy(MAXDOAS) measurements for Glyoxal(CHOCHO) in Beijing, China(39.95°N, 116.32°E). CHOCHO is the smallest compound of di-carbonyl group. As a primary sink of CHOCHO, its photolysis with NOx(oxides of nitrogen) results in the production of tropospheric ozone. Therefore,the focus of CHOCHO DOAS measurements is increasing in trend. We did the measurements from 09 May 2017 to 09 September 2017. The study was conducted to compare different retrieval settings in order to reveal best DOAS fit settings for CHOCHO;furthermore, effect of haze and non-haze days on CHOCHO concentration was examined.The root mean square of residual and Differential Slant Column density(dSCD) error was reduced when measurements were done with lower wavelength limit around 432–438 nm and upper intervals around 455–460 nm. Thus, lower wavelength intervals around432–438 nm and upper intervals around 457–460 nm were best for the retrieval of dSCDs for CHOCHO. Meteorological conditions like haze or non-haze days did not have significant effect on DOAS fit parameters. The CHOCHO vertical column densities range from 1.33 E +14 to 9.77 E + 14 molecules/cm2 during the study period with average of 6.16 E +14 molecules/cm2. The results indicated that during haze days CHOCHO concentration was higher because of lower rate of photolysis and atmospheric oxidation potential. Our results did not show any significant weekend effect on CHOCHO atmospheric concentration. | Zeeshan Javed Cheng Liu Muhammad Fahim Khokhar Chengzhi Xing Wei Tan Muhammad Ahmed Subhani Abdul Rehman Aimon Tanvir | 2019 | Journal of Environmental Sciences2019，31，6： | 3 |
| 6 | Microstructure analysis and thermoelectric properties of iron doped CuGaTe_(2)显示文摘Chalcopyrite related compounds have attracted much attention in recent years due to their promising thermoelectric properties.In this research we report Fe doping in chalcopyrite-type CuGaTe_(2)and its influence on structural and thermal transport properties.We synthesized polycrystalline samples with composition CuGa_(1-x)Fe_(x)Te_(2)with x=0.0 to 0.05 by spark plasma sintering method.For structural analysis powder X-ray diffraction and electron probe micro analysis were employed.Solubility of Fe in CuGaTe_(2)was found to be very small,and other phases like FeTe_(2)and CuTe were identified.Thermal conductivity showed a significant decrease with the addition of Fe up to x=0.02,which started to increase for x≥0.03.On the other hand,the addition of Fe caused slight increase in the power factor from 1.3mW/K^(2)m for x=0.0 to 1.6 mW/K^(2)m for x=0.02 at T=770 K.As a result,ZT peak value of 0.92 is recorded for x=0.02 at 870 K,which corresponds to an enhancement of 60%from that of non-doped CuGaTe_(2).This work demonstrates that thermoelectric properties of compositematerials can be greatly improved by controlling its microstructure. | Fahim Ahmed Naohito Tsujii Takao Mori | 2018 | Journal of Materiomics2018，4，3： | 3 |
| 7 | Regulatory mechanisms of microbial homeostasis in insect gut显示文摘Insects live in incredibly complex environments.The intestinal epithelium of insects is in constant contact with microorganisms,some of which are beneficial and some harmful to the host.Insect gut health and function are maintained through multidimensional mechanisms that can proficiently remove foreign pathogenic microorganisms while effectively maintaining local symbiotic microbial homeostasis.The basic immune mechanisms of the insect gut,such as the dual oxidase-reactive oxygen species(Duox-ROS)system and the immune deficiency(Imd)-signaling pathway,are involved in the maintenance of microbial homeostasis.This paper reviews the role of physical defenses,the Duox-ROS and Imd signaling pathways,the Janus kinase/signal transducers and activators of transcription signaling pathway,and intestinal symbiotic flora in the homeostatic maintenance of the insect gut microbiome. | Shuai Bai Zhichao Yao Muhammad Fahim Raza Zhaohui Cai Hongyu Zhang | 2021 | Insect Science2021，28，2： | 3 |
| 8 | CLM4.5对中国区域夏季土壤湿度的模拟研究显示文摘利用CESM (Community Earth System Model)框架最新发布的陆面模式CLM4.5模拟得到中国区域1991~ 2010年7月份0~ 10 cm的土壤湿度数据集;并以中国农作物生长发育和农田土壤湿度旬值数据集的土壤湿度作为实测值,与模拟结果进行了比较分析.结果表明CLM4.5能够揭示中国区域7月份0~10 cm土壤湿度的空间分布特征,与实测数据土壤湿度的年际变化趋势保持着较好的一致性.利用曼-肯德尔法进行突变现象检测表明,模拟和实测得到的二十年的土壤湿度在华北、东北地区有逐年减小的趋势,尤其是东北地区土壤变干现象尤为明显;而华东、华中地区的土壤湿度以2~3年为周期增减,并没有一个持续稳定的变化趋势.CLM4.5模拟的土壤湿度值普遍偏高,最大偏差超过0.1 mm3·mm-3,这可能与模式的参数化方案有关,在以今后的研究中有待进一步探索. | 王迪 沈润平 师春香 李明 张悦 Ahmad M Fahim | 2015 | 科学技术与工程2015，35，17： | 3 |
| 9 | 传统溶剂提取法和超临界流体萃取法对钟花蒲桃次生代谢产物的回收率的比较研究(英文)显示文摘目的:寻求一种最佳的钟花蒲桃次生代谢产物的萃取方法,以实现在工业上的应用。创新点:全面深入地比较传统溶剂提取法和超临界流体萃取法对钟花蒲桃的主要次生代谢产物的回收率。方法:在超临界流体萃取法中,应用Box-Behnken设计,以压力、温度和萃取粒径大小为自变量,以粗提取物、个别的和总的次生代谢产物的百分比产量为因变量。另外,还研究了调节剂乙醇对产量的影响。在传统溶剂提取中,结合十种不同的溶剂和三不同的技术(浸提、索氏和回流)产生二十种不同的提取产物。通过高效液相色谱法检测不同的提取方法对钟花蒲桃的主要次生代谢产物的回收率。结论:超临界流体萃取法优于传统溶剂提取法,省成本又省时。因此在工业使用上,超临界流体萃取法可替代传统溶剂提取法。 | Abdul Hakeem MEMON Mohammad Shahrul Ridzuan HAMIL Madeeha LAGHARI Fahim RITHWAN Salman ZHARI Mohammed Ali Ahmed SAEED Zhari ISMAIL Amin Malik Shah Abdul MAJID | 2016 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2016，17，9： | 2 |
| 10 | La^3+ doped LiCo0.25Zn0.25Fe2O4 spinel ferrite nanocrystals:Insights on structural,optical and magnetic properties显示文摘This paper addresses the manipulation of structural,morphology,optical and magnetic properties of LiCo0.25Zn0.25Fe2 O4 ferrite via incorporation of different proportions of La^3+at the expense of iron ions using a sol-gel method.The samples were characterized using the X-ray diffraction technique(XRD),Fourier transform infrared(FT-IR)spectroscopy,the energy dispersive X-ray spectra(EDX),inductively coupled plasma optical emission spectroscopy(ICP-OES),high resolution scanning electron microscopy(SEM),Brunauer-Emmett-Teller(BET)surface area analysis,ultraviolet-diffuse reflectance spectroscopy(UV-DRS),and vibrating sample magnetometer(VSM)technique.The Rietveld refinements of the samples indicate that at higher concentrations of La^3+,nanostructures with dual phase,i.e.cubic spinel and orthorhombic LaFeO3 perovskite with space group(Pbnm)appear.Optical studies show that the energy band gap(Eg)of the bare LiCo0.25Zn0.25Fe2 O4 ferrite sample(2.18 eV)reaches up to 2.47 eV at x=0.06 and above this concentration,it drops sharply to 2.00 eV.Although the saturation magnetization and the coercivity of LiCo0.25Zn0.25LaxFe2-xO4 are lower than that of LiCo0.25Zn0.25Fe2 O4 NPs.Overall,the superparamagnetic nature and low values of saturation magnetization and coercivity of LiCo0.25Zn0.25LaxFe2-xO4 NPs are suitable to be applied in transformers core. | M.I.A.Abdel Maksoud Ahmed El-Ghandour A.H.Ashour M.M.Atta Soraya Abdelhaleem Ahmed H.El-Hanbaly Ramy Amer Fahim Said M.Kassem M.S.Shalaby A.S.Awed | 2021 | Journal of Rare Earths2021，39，1： | 2 |
| 11 | Evaluation of factors affecting psychological morbidity in emergency medicine practitioners显示文摘BACKGROUND: Assessing and evaluating mental health status can provide educational planners valuable information to predict the quality of physicians' performance at work. These data can help physicians to practice in the most desired way. The study aimed to evaluate factors affecting psychological morbidity in Iranian emergency medicine practitioners at educational hospitals of Tehran.METHODS: In this cross sectional study 204 participants(emergency medicine residents and specialists) from educational hospitals of Tehran were recruited and their psychological morbidity was assessed by using a 28-question Goldberg General Health Questionnaire(GHQ-28). Somatization, anxiety and sleep disorders, social dysfunction and depression were evaluated among practitioners and compared to demographic and job related variables.RESULTS: Two hundreds and four participants consisting of 146(71.6%) males and 58(28.4%) females were evaluated. Of all participants, 55(27%) were single and 149(73%) were married. Most of our participants(40.2%) were between 30–35 years old. By using GHQ-28, 129(63.2%) were recognized as normal and 75(36.8%) suffered some mental health disorders. There was a signifi cant gender difference between normal practitioners and practitioners with disorder(P=0.02) while marital status had no significant difference(P=0.2). Only 19(9.3%) declared having some major mental health issue in the previous month.CONCLUSION: Females encountered more mental health disorders than male(P=0.02) and the most common disorder observed was somatization(P=0.006). | Mehdi Momeni Farshid Fahim Elnaz Vahidi Amir Nejati Morteza Saeedi | 2016 | World Journal of Emergency Medicine2016，7，3： | 2 |
| 12 | Low-power direct digital frequency synthesis for wireless communications 显示文摘 | BELLAOUAR A OBRECHT M S FAHIM A M | 2000 | IEEE Journal of Solid-State Circuits2000，35，3： | 1 |
| 13 | System dynamics approach to analyzing the cost factors effects on cost of quality 显示文摘 | BEHDAD K HADI S FAHIME K B | 2009 | International Journal of Quality & Reliability Management2009，26，7： | 1 |
| 14 | Progressive collapse analysis of seismically designed steel braced frames 显示文摘 | Kapil Khandelwal Sherif E1-Tawil Fahim Sadek | 2009 | Journal of Constructional Steel Research2009，65，3： | 1 |
| 15 | Functional role of CD4+ CD25+ regulatory T cells and transforming growth factor-betal in childhood immune thrombocytopenic purpura显示文摘 | Fahim NM Monir E | 2006 | Egypt J Immunol2006，13，1： | 1 |
| 16 | Hairpin RNAderived from viral NIa gene confers immunity to wheat streakmosaic virus infection in transgenic wheat plants显示文摘 | Fahim M Ayala-Navarrete L Miller A A | 2010 | Plant Bi-otechnology Journal2010，8，7： | 1 |
| 17 | Liquid-liquid equilibria for the extraction of aromatics from naphtha reformate by dimethylformamide/ethylene glycol mixed solvent显示文摘 | Radwan G M Fahim M A Almuhtaseb S A | 1997 | Fluid Phase Equilibria1997，129，12： | 1 |
| 18 | Functional role of CD4^+ CD25^+ regulatory T cells and transforming growth factor-beta 1 in childhood immune thromboeytopenic purpura显示文摘 | Fahim NM Monir E | 2006 | Egypt J Immunol2006，13，1： | 1 |
| 19 | Vitamin E ameliorates the de- cremental effect of paraquat on cardiomyocyte contractility in rats 显示文摘 | Fahim MA Howarth FC Nemmar A | 2013 | PLoS One2013，8，57： | 1 |
| 20 | Cardiovascular toxicity of ionophores used as feed additives 显示文摘 | Pressman BC Fahim M | 1983 | Adv Exp Med Biol1983，161，： | 1 |
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