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| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | Inhibition of LTP in vivo by beta-amyloid peptide in different conformational states显示文摘 | Schmid A W Freir D B Herron C E | 2008 | Brain research2008，1197，： | 1 |
| 3 | Nanoscale friction and wear mechanisms at the interface between a boron carbide film and an atomic force microscope tip 显示文摘 | PRIOLI R REIGADA D C FREIRE F L | 2000 | Journal of Applied Physics2000，87，3： | 1 |
| 4 | Effect of Moxibustion at Acupoints Ren-12 (Zhongwan),St-25 (Tianshu),and St-36 (Zuzanli) in the Prevention of Gastric Lesions Induced by Indomethacin in Wistar Rats显示文摘 | Freire A O Sugai G C Blanco M M | | 0，，02： | 1 |
| 5 | Zn-Ni Alloy Deposits Obtained by Continuous and Pulsed Electrodeposition Processes显示文摘 | PAGOTTO JR S O DE ALVARENGA FREIRE C M BALLESTER M | 1999 | Surface and Coatings Technology1999，122，： | 1 |
| 6 | Production of Coated Papers with Improved Properties by Using a Water-soluble Chitosan Derivative显示文摘 | FERNANDES S C M FREIRE C S R SILVESTRE A J D | 2010 | Ind Eng Chem Res2010，49，14： | 1 |
| 7 | Panic disorder and social anxiety disorder subtypes in a caffeine challenge test显示文摘 | Nardi A E Lopes F L Freire R C | | 0，，02： | 1 |
| 8 | Epithelial transport of magnesium in the kidney of fish显示文摘 | Beyenbach K W Freire C A Kinne R K | 1993 | Miner Electrolyte Metab1993，19，45： | 1 |
| 9 | A New Procedure for Treatment of Oily Slurry Using Geotextile Filters 显示文摘 | Mendoncaa M B Cammarotab M C Freire B D | 2004 | Journal of Hazardous Materials2004，110，： | 1 |
| 10 | Fungal laccase: copper induction, semi-purification, immobilization, phenolic effluent treatment and electrochemical measurement显示文摘 | CORDI L MINUSSI R C FREIRE R S | 2010 | Aft J Bioteehnol2010，6，10： | 1 |
| 11 | Correlation between nano-scale friction and wear of boron carbide films deposited by dc-magnetron sputtering显示文摘 | Prioli R Reigada D C Freire F L | 1999 | Appl Phys Lett1999，75，9： | 1 |
| 12 | Studies on the electrochemical behavior of a eystine self-assembled monolayer modified electrode using ferro- cyanide as a probe 显示文摘 | Valber A Pedrosa Thiago R L C Paixlio Renato S Freire | 2007 | J Electroanal Chem2007，602，2： | 1 |
| 13 | The subimplantation model for diamond-like carbon films deposited by methane gas decomposition 显示文摘 | Lacerda R G Marques F C Freire Jr F L | 1999 | Diamond and Related Materials1999，8，： | 1 |
| 14 | Study of the diffusion coefficients of diphenylbutadiene and triclosan into and within meat显示文摘 | Sanches Silva A Freire J M C Losada P P | 2010 | European Food Research and Technology2010，230，6： | 1 |
| 15 | CAD tools to optimize power MOSFET performance using channel reverse conduction显示文摘 | Castro Simas M I Freire J C | 1994 | IEEE Transactions on Power Electronics1994，9，5： | 1 |
| 16 | Structural assessment of minor axis steel joints using photoelasticity and finite elements 显示文摘 | Lima L R O Freire J L F Vellasco P C G S | 2009 | Journal of Constructional Steel Research2009，65，2： | 1 |
| 17 | Bloodstream infection caused by extensively drag-resistant Acinetobacter baumannii in cancer patients: high mortality associated with delayed treatment rather than with the degree of neutropenia显示文摘 | Freire M P de Oliveira Garcia D Garcia C P | 2015 | Clin Microbiol Infect2015，，： | 1 |
| 18 | Visceral Leishmaniasis in A New Ecological Niche Near A major Metropolitan Area of Brazil 显示文摘 | Cunha S Freire M Eulalio C | 1995 | Transactions of the Royal Society of Tropical Medicine and Hygiene1995，89，： | 1 |
| 19 | Coffee flavour: an overview显示文摘 | Buffo R A Cardelli - Freire C | 2004 | Flavour and Fragrance Journal2004，19，2： | 1 |
| 20 | Corporate so-cial responsibility, firm value and financial performance inBrazil显示文摘 | VICENTE L C FREIRE F S FELIPE C V | 2011 | Social Responsibility Journal2011，7，2： | 1 |
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