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	题名	作者	年代	出处	被引量
1	Ghrelin attenuates gastrointestinal epithelial damage induced by doxorubicin显示文摘AIM:To examine the influence of ghrelin on the regenerative potential of gastrointestinal(GI)epithelium.METHODS:Damage to GI epithelium was induced in mice by two intravenous injections of doxorubicin(10 and 6 mg/kg).Some of the doxorubicin-treated mice received a continuous subcutaneous infusion of ghrelin(1.25μg/h)for 10 d via implanted mini-osmotic pumps.To label dividing stem cells in the S-phase of the cell cycle,all mice received a single intraperitoneal injection of 5'-bromo-2'-deoxyuridine(BrdU)one hour before sacrifice.The stomach along with the duodenum were then removed and processed for histological examination and immunohistochemistry using anti-BrdU antibody.RESULTS:The results showed dramatic damage to the GI epithelium 3 d after administration of chemotherapy which began to recover by day 10.In ghrelintreated mice,attenuation of GI mucosal damage was evident in the tissues examined postchemotherapy.Immunohistochemical analysis showed an increase in the number of BrdUlabeled cells and an alteration in their distribution along the epithelial lining in response to damage by doxorubicin.In mice treated with both doxorubicin and ghrelin,the number of BrdUlabeled cells was reduced when compared with mice treated with doxorubicin alone.CONCLUSION:The present study suggests that ghrelin enhances the regenerative potential of the GI epithelium in doxorubicintreated mice,at least in part,by modulating cell proliferation.	Mohamed A Fahim Hazem Kataya Rkia El-Kharrag Dena AM Amer Basel al-Ramadi Sherif M Karam	2011	World Journal of Gastroenterology2011，17，33：	3
2	Low-power direct digital frequency synthesis for wireless communications 显示文摘	BELLAOUAR A OBRECHT M S FAHIM A M	2000	IEEE Journal of Solid-State Circuits2000，35，3：	1
3	Hairpin RNAderived from viral NIa gene confers immunity to wheat streakmosaic virus infection in transgenic wheat plants显示文摘	Fahim M Ayala-Navarrete L Miller A A	2010	Plant Bi-otechnology Journal2010，8，7：	1
4	Liquid-liquid equilibria for the extraction of aromatics from naphtha reformate by dimethylformamide/ethylene glycol mixed solvent显示文摘	Radwan G M Fahim M A Almuhtaseb S A	1997	Fluid Phase Equilibria1997，129，12：	1
5	Vitamin E ameliorates the de- cremental effect of paraquat on cardiomyocyte contractility in rats 显示文摘	Fahim MA Howarth FC Nemmar A	2013	PLoS One2013，8，57：	1
6	Prediction of predominant mechanisms in the separation of secondary disperstions in a fibrous bed显示文摘	Othamn F M Fahim M A Jeffreys G V	1988	Dispersion Science and Technology1988，9，2：	1
7	Role of laparoscopiccholecystectomy in the management ofgangrenous cholecystitis显示文摘	Fahim A Habib MD Ram B et a l	2001	TheAmerican Journalof Surgery2001，181，1：	1
8	Optimization of aromatics extraction of naphtha reformate by propylene carbonate/diethylene glycol mixed solvent显示文摘	Lababidi H M S Ali S H Fahim M A	2006	Industrial & Engineering ChemistryResearch2006，45，14：	1
9	Prediction and measurement of phase equilibria for the extraction of BTX from naphtha reformate using BMIMPF6 ionic liquid显示文摘	A1-Rashed O A Fahim M A Shaaban M	2014	Fluid Phase Equilibria2014，363，：	1
10	Effects of progesterone administration on infarct volume and functional deficits following permanent focal cerebral ischemia in rats显示文摘	Tauheed I Iqbal S Fahim A	2009	Brain Res2009，1257，：	1
11	Vitamin E ameliorates the decremental effect of paraquat on cardiomyocyte contractility in rats 显示文摘	Fahim MA Howarth FC Nemmar A	2013	PLoS One2013，8，57：	1
12	Neural networks representation of a vehicle model:‘ Neuro - Vehicle (NV) '显示文摘	Ghazizadeh A Fahim A El- Gindy M	1996	International Journal of Vehicle Design1996，17，1：	1
13	Serum carcinoembryonic antigen correlates with severity of idiopathic pulmonary fibrosis显示文摘	Fahim A Crooks MG Wilmot R	2012	Respirotogy2012，17，8：	1
14	A wideband sigma-delta phase-locked-loop modulator for wireless applications显示文摘	Fahim A M	2003	IEEE Trans Circ and SystⅡ:Analog and Dig Signal Proc2003，50，2：	1
15	The effect of explicit teaching of English“thanking formulas” on Iranian EFL intermediate level studentsat English language institutes 显示文摘	Ghobadi A Fahim M	2009	System2009，37，3：	1
16	Pulmonarysarcoidosis:diagnosticandtreat-mentupdate显示文摘	Fahim A MannJS	2014	ExpertRevRespirMed2014，8，4：	1
17	Low-power direct digital frequency synthesis for wireless communications显示文摘	BELLAOURA A MICHAEL S FAHIM A M	2000	IEEE Journal of Solid-State Circuits2000，35，3：	1
18	Differential hemodynamic brain activity in schizophrenia patients with blunted affect during quetiapine treatment显示文摘	Fahim C Stip E Mancini-Mar'ie A	2005	J Clin Psychopharmacol2005，25，4：	1
19	Low-power direct digital frequency synthesis for wireless communications 显示文摘	BELLAOUAR A O'BRECHT M S FAHIM A M	2000	IEEE J Sol Sta Circ2000，35，3：	1
20	Idiopathic interstitial pneumonias显示文摘	Fahim A Hart SP	2009	Respiratory Medicine CME2009，2，2：	1

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