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| 1 | Associations of sense of coherence with psychological distress and quality of life in inflammatory bowel disease显示文摘AIM:To investigate the relationship between sense of coherence,psychological distress and health related quality of life in inflammatory bowel disease(IBD).METHODS:This cross-sectional study enrolled a consecutive sample of 147 IBD(aged 45.1 ± 14.1 years; 57.1% female) patients recruited from a tertiary gastroenterology service.Sixty-four participants met diagnostic criteria for Crohn's disease,while eightythree patients had ulcerative colitis.Socio-demographic data(education,age,race,gender,gross monthly income and marital status),disease-related variables(illness activity,relapse rate in past 2 years,history of surgery and time since diagnosis),sense of coherence(Antonovsky's SOC scale),psychological distress symptoms(Hospital Anxiety and Depression Scale) and health-related quality of life(HRQo L; WHOQOLBref) were assessed.Hierarchical multiple regression analyses were performed to identify factors that are independently associated with psychological distress and HRQo L in patients with IBD and to provide indications for possible moderating or mediating effects.In addition,formal moderation and mediation analyses(Sobel tests) were performed to confirm potential moderators/mediators of the relationship between SOC,psychological distress symptoms and HRQoL.RESULTS:Lower SOC scores(std beta=-0.504; P < 0.001),female gender(std beta = 0.176; P = 0.021) and White race(std beta = 0.164; P = 0.033) were independently associated with higher levels of depressive symptoms,while lower levels of SOC(std beta =-0.438; P < 0.001) and higher relapse rate(std beta = 0.161; P = 0.033) were independently associated with more severe anxiety symptoms.A significant interaction between time since diagnosis and SOC was found with regard to the severity of depressive or anxiety symptoms,as the interaction term(time since diagnosis X SOC) had beta coefficients of-0.191(P = 0.009) and-0.172(P = 0.026),respectively.Lower levels of anxiety symptoms(std beta =-0.369; P < 0.001),higher levels of SOC(std beta = 0.231; P = 0.016) and non-White race(std beta =-0.229; P = 0.006),i.e.,mixed-race,which represented the reference category,were independently associated with higher levels of overall HRQoL.Anxiety symptoms were the most potent independent correlate of most aspects of HRQoL.In addition,anxiety mediated the association between SOC and satisfaction with health,as well as its relationship with physical,mental,and social relations HRQo L.Depressive symptoms also mediated the association between SOC and mental HRQoL.CONCLUSION:Our data indicated that SOC is an important construct,as it influences psychological distress and has significant albeit indirect effects on several HRQoL domains in IBD. | Thiago H Freitas Elias Andreoulakis Gilberto S Alves Hesley LL Miranda Lúcia LBC Braga Thomas Hyphantis André F Carvalho | 2015 | World Journal of Gastroenterology2015，21，21： | 10 |
| 2 | Rheological characterization of egg yolk processed by spraydrying and lipid-cholesterol extraction with carbon dioxide显示文摘 | Miranda J Partal P Cordobes F | 2002 | Journal of the American Oil chemists society2002，79，2： | 1 |
| 3 | Can- diduria in hospital patients: a study prospective 显示文摘 | KOBAYASHI C C DE FERNANDES O F MIRANDA K C | 2004 | Mycopathologia2004，158，1： | 1 |
| 4 | Xanthohu- mol, a prenylflavonoid derived from hops induces apoptosis and inhibits NF-kappaB activation in prostate epithelial cells 显示文摘 | Colgate E C Miranda C L Stecens J F | 2007 | Cancer letters2007，246，1： | 1 |
| 5 | A K-band tunable microstrip bandpass filter using a thin-film conductor/ferroelectric/dielectric multilayer configuration 显示文摘 | Subramanyam G Van Keuls F Miranda F A | 1998 | Microwave and Guided Wave Letters IEEE1998，8，2： | 1 |
| 6 | Finite element modeling as a tool for predicting the fracture behavior of robocast scaffolds显示文摘 | Miranda P Pajares A Guiberteau F | | 0，，06： | 1 |
| 7 | Wavelet analysis of lightning return stroke 显示文摘 | Miranda F J | 2008 | Journal of Atmospheric and Solar-Terrestrial Physics2008，70，1112： | 1 |
| 8 | Semivariogram textural classification of JERS-1(FUYO-1) SAR data obtained over a flooded area of the Amazonian rainforest显示文摘 | Miranda F P Fonseca L E N Carr J R | 2000 | International Journal of Remote Sensing2000，19，3： | 1 |
| 9 | Influence of anthropo- metric variables in C reactive protein显示文摘 | Tim6teo AT Miranda F Felieiano J | 2011 | Acta Med Port2011，24，3： | 1 |
| 10 | Forme fruste of neuroleptic ma- lignant syndrome associated with the use of sertraline 显示文摘 | Miranda M Soto F Fischman P | 2011 | Parkin- sonism Relat Disord2011，17，3： | 1 |
| 11 | Personality and Team Performance : A Meta - Analysis 显示文摘 | Miranda A G Peeters Harrie F J M Vantuijl Christel G Rutte Isabelle M M J Reymen | 2006 | European Journal of Personality2006，，20： | 1 |
| 12 | Identification of a putative estrogenresponse element in the gene encoding brain-derived neurotrophic factor显示文摘 | Sohrabji F Miranda RC Toran-Allerand CD | 1995 | Proc Natl AcadSci USA1995，92，11： | 1 |
| 13 | Effects of plough pan development on surface hydrology and on soil physical properties in Southeastern Brazilian pla- teau显示文摘 | Bertolino Aria V F A Fernandes N F Miranda J P L | 2010 | J Hydro2010，393，12： | 1 |
| 14 | Metabolic correction in the management of diabetic peripheral neuropa- thy: improving clinical results beyond symptom control显示文摘 | Miranda Massari JR Gonzalez MJ Jimenez F J | 2011 | Curr Clin Pharmacol2011，6，4： | 1 |
| 15 | Bioaccumu- lation of chlorinated pesticides and PCBs in the tropi- cal freshwater ftsb Hoplias malabaricus: Histopathologi- cal, physiological, and immunological findings 显示文摘 | Miranda A L Roche H Randi M A F | 2008 | En- vironment International2008，34，7： | 1 |
| 16 | Salt-inducible ki-nase 2 links transcriptional coactivator p300 phosphorylation tothe prevention of ChREBP-dependent hepatic steatosis in mice显示文摘 | Bricambert J Miranda J Benhamed F | 2010 | J Clin Invest2010，120，12： | 1 |
| 17 | Newinsight on the so-lidification path ofan alloy 625 weld overlay显示文摘 | Silva C C Miranda H C D Motta M F | 2013 | Journal of Materi- als Research and Technology2013，2，3： | 1 |
| 18 | To- wards the development of colorimetric probes to discrimi- nate between isomeric dicarboxylates显示文摘 | Saneenon F Martinez-Manez R Miranda M A | 2003 | Angew Chem Int Ed2003，42，： | 1 |
| 19 | Antinociceptive and anti - exudative synergism between dexketoprofen and tramad- ol in a model of inflammatory pain in mice 显示文摘 | MIRANDA H F ROMERO M A PUIG M M | 2012 | Fundam Clin Pharmacol2012，26，3： | 1 |
| 20 | Oral lichen planus:Topical and systemic therapy 显示文摘 | Lozada-Nur F Miranda C | 1997 | Semin Cutan Med Surg1997，16，4： | 1 |
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