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138篇 您的检索式：作者名="Espada"

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	题名	作者	年代	出处	被引量
1	A role for the Tgf-β/Bmp co-receptor Endoglin in the molecular oscillator that regulates the hair follicle cycle显示文摘The hair follicle is a biological oscillator that alternates growth,regression,and rest phases driven by the sequential activation of the proliferation differentiation programs of resident stem cell populations.The activation of hair follicle stem cell niches and subsequent entry into the growing phase is mainly regulated by Wnt/β-catenin signalling,while regression and resting phases are mainly regulated by Tgf-β/Bmp/Smad activity.A major question still unresolved is the nature of the molecular switch that dictates the coordinated transition between both signalling pathways.Here we have focused on the role of Endoglin(Eng),a key co-receptor for members of the Tgf-β/Bmp family of growth factors.Using an Eng haploinsufficient mouse model,we report that Eng is required to maintain a correct follicle cycling pattern and for an adequate stimulation of hair follicle stem cell niches.We further report thatβ-catenin binds to the Eng promoter depending on Bmp signalling.Moreover,we show thatβ-catenin interacts with Smad4 in a Bmp/Eng-dependent context and both proteins act synergistically to activate Eng promoter transcription.These observations point to the existence of a growth/rest switching mechanism in the hair follicle that is based on an Eng-dependent feedback cross-talk between Wnt/β-catenin and Bmp/Smad signals.	Maria I.Calvo-Sanchez Sandra Fernandez-Martos Elisa Carrasco Gema Moreno-Bueno Carmelo Bernabeu Miguel Quintanilla Jesus Espada	2019	Journal of Molecular Cell Biology2019，11，1：	7
2	MeSH pesticide trace analysis using solid-phase extraction and gas chromatography with electron capture and tandem mass spectrometric detection in water samples显示文摘	Martinez Vidal J L Pablos Espada M C Garrido Frenich A		Jounal of Chromatography A0，，：	2
3	Non-small cell lung cancer staging techniques and endoscopic ultrasound:tissue is still the issue显示文摘	LeBlanc JK Espada R Ergun G	2003	Chest2003，123，5：	1
4	HPLC assay for determination of amphotericin B in biological samples显示文摘	ESPADA R JOSA J M VALDESPINA S	2008	Biomed Chromatogr2008，22，4：	1
5	Vitamin D3 promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of β-catenin signaling 显示文摘	Palmer HG Gonzalez-Sancho JM Espada J	2001	J Cell Biol2001，154，2：	1
6	Sequential development of 2 connective tissue disease in juvenile patients显示文摘	Citera G Espada G Moldonado JA	1993	J Rheumatal1993，20，12：	1
7	Test of correcting iron deficiency chlorosis in peach trees 显示文摘	Espada J L	1982	Information Tecnica Economica Agraria1982，13，47：	1
8	Methamphetamine causes degeneration of dopamine cell bodies and terminals of the nigrostriatal pathway evidenced by silver staining 显示文摘	ARES-SANTOS S GRANADO N ESPADAS I	2014	Neuropsychopharmacology2014，39，5：	1
9	A tenant-based resource allocation model for scaling software-as-a-service applications over cloud computing infrastructures显示文摘	ESPADAS J MOLINA A JIMENEZ G1 MOLINA M RAMIRE R CONCHA D	2013	Future Generation Computer Systems2013，29，1：	1
10	Cultivating in vitro coconut palms(Cocos nucifera L)under glasshouse conditions with natural light,improves in vitro photosynthesis nursery survival and growth显示文摘	TALAVERA C CONTRERAS F ESPADAS F	2001	Plant Cell Tissue and Organ Culture2001，83，：	1
11	A Tenant-based Resource Allocation Model for Scaling Software-as-a-Service Appli- cations over Cloud Computing Infrastructures显示文摘	Espadas J Molina A Jimenez G	2011	Future Generation Computer Systems2011，25，6：	1
12	Characterization of bacteria associated with pine wood nematode Bursaphelenchus xylophilus显示文摘	Vicente C Nascimento F Espada M	2012	Plos One2012，7，10：	1
13	Ferrocenylenesilylene polymers as coatings for tapered opticalfiber gas sensors显示文摘	ESPADA L I SHADAREM M ROBILLARD J	2000	J Inorg Organomet Polyrn2000，10，4：	1
14	Test of correcting iron deficiency chlorosis in peach trees显示文摘		1982	ITEA1982，，47：	1
15	The purinergic P2Y(13)receptor activates the Nrf2/HO-l axis and protects against oxidative stress-induced neuronal death显示文摘	Espada S Ortega F Molina-Jijan E	2010	Free Radic Biol Med2010，49，：	1
16	Effect of Chia oil (Salvia Hispanica) rich in omega-3 fatty acids on the eicosanoid release,apoptosis and T-lymphocyte tumor infiltration in a murine mammary gland adenocarcinoma显示文摘	Espada CE Berra MA Martinez MJ	2007	Prostaglandins Leukot Essent Fatty Acids2007，77，1：	1
17	Relation be- tween substance use and depression among Spanish adolescents 显示文摘	Espada JP Sussman S Huedo Medina TB	2011	International Journal of Psychology and Psychological Ther- apy2011，11，1：	1
18	A tenant-based resource allocation model for scaling software-as-a-service applications over cloud computing infrastructures 显示文摘	ESPADAS J MOLINA A JIMENEZ G	2012	Future Generation Computer Systems2012，29，1：	1
19	Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of β-catenin signaling显示文摘	Palmer HG Gonzalez-Sancho JM Espada J	2001	J Cell Biol2001，154，2：	1
20	First insights into the genetic diversity of the pine wood nematode in its native area using new polymorphic microsatellite loci显示文摘	Mallez S Castagnone C Espada M	2013	PLoS ONE2013，8，59：	1

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