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| 1 | 采用先进的深枪喂钙线钢包处理法改进工艺控制及提高钢质量显示文摘<正> 在过去的九年中,在冶炼高质量钢方面,喂线技术作为一种实现钙处理的经济有效方法,已经得到了世界范围的广泛认可。1975年,Pfizer通过采用Pferrocal~*包芯线在北美首创了喂线技术。这些早期的试验结果不仅表明了喂线的有效性,而且还对流体力学和热力学条件进行了限定,特别是需要使用纯钙的条件。 | MARK J ENGEL 张开坚 | 1993 | 钢铁钒钛1993，14，1： | 4 |
| 2 | On tolerability and safety of a maintenance treatment with 6-thioguanine in azathioprineor 6-mercaptopurine intolerant IBD patients显示文摘AIM: To determine the tolerability and safety profile of a low-dose maintenance therapy with 6-TG in azathioprine (AZA) or 6-mercaptopurine (6-MP) intolerant inflammatory bowel disease (IBD) patients over a treatment period of at least 1 year.METHODS: Database analysis.RESULTS: Twenty out of ninety-five (21%) patients discontinued 6-TG (mean dose 24.6 mg; mean 6-TGN level 540 pmol/8×108 RBC) within 1 year. Reasons for discontinuation were GI complaints (31%), malaise (15%)and hepatotoxicity (15%). Hematological events occurred in three patients, one discontinued treatment. In the 6-TG-tolerant group, 9% (7/75) could be classified as hepatotoxicity. An abdominal ultrasound was performed in 54% of patients, one patient had splenomegaly.CONCLUSION: The majority of AZA or 6-MP-intolerant IBD patients (79%) is able to tolerate maintenance treatment with 6-TG (dosages between 0.3 and 0.4 mg/kg per d). 6-TG may still be considered as an escape maintenance immunosuppressant in this difficult to treat group of patients, taking into account potential toxicity and efficacy of other alternatives. The recently reported hepatotoxicity is worrisome and 6-TG should therefore be administered only in prospective trials. | Nanne KH de Boer Luc JJ Derijks Lennard PL Gilissen Daniel W Hommes Leopold GJB Engels Sybrand Y de Boer Gijsbertus den Hartog Piet M Hooymans Anja BU M(?)kelburg Barend D Westerveld Anton HJ Naber Chris JJ Mulder Dirk J de Jong | 2005 | World Journal of Gastroenterology2005，11，35： | 4 |
| 3 | Presurgical evaluation for partial epilepsy: relative contributions of chronic depth-electrode recordings versus FDG-PET and scalp-sphenoidal ictal EEG显示文摘 | Henry TR Risinger MW | 1990 | Neurology1990，40，： | 1 |
| 4 | A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: Report of the ILAE Task Force on Classification and Terminology 显示文摘 | Engel J Jr International League Against Epilepsy (iLAE) | 2001 | Epilepsia2001，42，6： | 1 |
| 5 | Structural determinants of water permeation through aquaporin-1 显示文摘 | MIYAMOTO K MITSUOKA K HIRAI T WALZ T AGRE P HEYMANN J B ENGEL A FUJIYOSHI Y | 2000 | Nature2000，407，： | 1 |
| 6 | A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of the ILAE task force on classification and terminology显示文摘 | Engel J Jr | | Epilepsia0，42，6： | 1 |
| 7 | Evolutionary conservation in the untranslated regions of actin mRNAs:DNA sequence of a human beta-actin cDNA显示文摘 | Ponte P Ng S Engel J | 1984 | Nucl Acids Res1984，12，： | 1 |
| 8 | Systematic evaluation of genetic variants in the inflammation pathway and risk of lung cancer显示文摘 | Engels EA Wu X Gu J | | 0，，13： | 1 |
| 9 | Characterization of dissolved organic matter in cave and spring waters using UV-Vis absorbance and fluorescence spectroscopy 显示文摘 | Birdwell J E Engel A S | 2010 | Organic Geochemistry2010，41，3： | 1 |
| 10 | Initiators for endothermic fuels 显示文摘 | Wickham D T Engel J R Hitch B D etal | 2001 | J Propul Power2001，17，： | 1 |
| 11 | Spatial load forecasting显示文摘 | Willis H L Engel M V Buri M J | 1995 | IEEE Computer Applications in Power1995，8，2： | 1 |
| 12 | Population-based hormone receptor-specific incidence trends of breast cancer in Germany显示文摘 | Rusner C Bandemer-Greulich U Engel J | 2012 | Maturitas2012，73，2： | 1 |
| 13 | Dynamics of GATA transcription factor expression during erythroid differentiation 显示文摘 | Leonard M Brice M Engel J D | 1993 | Blood1993，82，4： | 1 |
| 14 | Explaining investment dynamics in US Manufacturing: A generalized (S, s) approach显示文摘 | Caballero R J Engel E M R A | 1999 | Econometrica1999，67，4： | 1 |
| 15 | ILAE commission report, a proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of the ILAE task force on classification and terminology 显示文摘 | Engel J | 2001 | Epilepsia2001，42，： | 1 |
| 16 | Continuous/discontinuous finite element approximations of fourth-order elliptic problems in structural and continuum mechanics with applications to thin beams and plates, and strain gradient elasticity显示文摘 | Garikipati K Hughes T J R | 2002 | Comput Methods Appl Mech Engng2002，191，： | 1 |
| 17 | Mesial temporal lobe epilepsy:what have we learned? 显示文摘 | Engel J Jr | 2001 | Neuroscientist2001，7，4： | 1 |
| 18 | PET scanning in partial epilepsy显示文摘 | Engel J Jr | 1991 | Can J Neurol Sci1991，18，4： | 1 |
| 19 | A proposed diagnostic scheme for people with epileptic seizures and with epilepsy:Report of the ILAE task force on classification and terminology显示文摘 | Engel J | 2001 | Eplilepsia2001，42，6： | 1 |
| 20 | More about the polymerization of lactides in the presence of stannous oc- toate 显示文摘 | Schwach G Coudane J Engel R | 1997 | Journal of Polymer Science: Part A: Polymer Chemistry1997，35，16： | 1 |
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