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| 1 | 骨盆底功能障碍的静态和动态MR成像表现显示文摘目的前瞻性地分析同期静态和动态MR影像,确定压力性尿失禁(SUI)、盆腔脏器脱出(POP)和肛门失禁是否与特定的盆底异常相关。方法本研究经伦理委员会批准,并获得所有受试者知情同意。共计59例女性,其中15例未生育女性(平均年龄25.6岁)为对照组,病人44例(平均年龄43.4岁)。病人组依据主要症状分为4组。结构紊乱分析采用静态T2加权扰相自旋回波影像,功能异常的诊断则采用功能动态(电影)平衡快速场回波影像。记录5个盆底支持结构的测量结果。两种MRI影像联合分析以确定主要异常。 | R.F. El Sayed S. El Mashed A. Farag M.M. Morsy M.S. A bdel Azim. 赵艳萍(译) 刘文亚(校) 唐光健(校) | 2008 | 国际医学放射学杂志2008，31，5： | 12 |
| 2 | Interaction of insulin with prokinetic drugs in STZ-induced diabetic mice显示文摘AIM:To study the possible interactions of metoclopramide,domperidone and erythromycin in streptozotocin-induced diabetic mice treated with insulin by various parameters.METHODS:Effects of the individual as well as combined drugs were studied in diabetic mice via estimation of the blood glucose and serum insulin levels,small intestinal transit(SIT),gastric emptying(GE),xylose absorption and glucose tolerance tests.Groups were given insulin 2 IU/kg s.c.,metoclopramide 20 mg/kg p.o.,domperidone 20 mg/kg p.o.and erythromycin 6 mg/kg p.o.individually and in combination.There were also normal and diabetic control groups.The first set of experiments was carried out to investigate the subchronic effect on blood glucose and serum insulin levels in diabetic mice of one week of daily dose administration of the tested drugs individually as well as the combination of insulin with each prokinetic drug.The other five sets of experiments were carried out to investigate the acute effect of a single dose of each drug individually and in combination on blood glucose and serum insulin levels,SIT,GE,oral xylose absorption and glucose tolerance tests.RESULTS:The study included the prokinetic drugs metoclopramide(20 mg/kg),domperidone(20 mg/kg) and erythromycin(6 mg/kg),as well as insulin(2 IU/kg),which was individually effective in decreasing SIT,enhancing GE and increasing xylose absorption significantly in diabetic mice.Erythromycin tended to decrease blood glucose level and increase serum insulin level after 1 wk of daily administration in diabetic mice.Erythromycin potentiated the effect of insulin on blood glucose level and serum insulin level whereas other prokinetic agents failed to do so after repeated dose administration in diabetic mice.Metoclopramide or erythromycin in combination with insulin significantly decreased SIT,in diabetic mice,to lower levels than with insulin alone.Administration of prokinetic drugs along with insulin antagonized the action of insulin on xylose absorption.These combinations also increased the rate of glucose absorption from the gut.CONCLUSION:The present study suggests that prokinetic drugs could potentially improve glycemic control in diabetic gastroparesis by allowing a more predictable absorption of nutrients,matched to the action of exogenous insulin.The use of prokinetics,such as erythromycin,may be interesting in the clinic in decreasing the need for insulin in diabetic patients.The dose of insulin may be safely decreased with erythromycin in chronic treatments. | Mohamed A Fouad Shalaby Hekma A Abd El Latif Mostafa E El Sayed | 2013 | World Journal of Gastrointestinal Pharmacology and Therapeutics2013，4，2： | 3 |
| 3 | The role of fringing coral reef in beach protection of Hurghada, Gulf of Suez, Red Sea of Egypt显示文摘 | Frihy O E El Ganaini M A El Sayed W R | 2004 | Ecological Engineering2004，22，1： | 1 |
| 4 | Au nanoparticles target cancer显示文摘 | Jain P K El - Sayed I H and El - Sayed M A | 2007 | Nano Today2007，2，1： | 1 |
| 5 | Effect of compatibilizing agents on the mechanical property of rice husk flour as nano-potential filler in polypropylene biocomposite显示文摘 | El Sayed A M | 2012 | Journal of Applied Polymer Science2012，125，2： | 1 |
| 6 | Fractional differential - difference equations显示文摘 | El - Sayed Ahamed M A | 1996 | Journal of Frac Calculus1996，10，： | 1 |
| 7 | Angiolymphoid hyperplasia with eosinophilia:efficacy of isotretinoin?显示文摘 | El Sayed F Dhaybi R Ammoury A | 2006 | Head Face Med2006，2，： | 1 |
| 8 | FTIR, TGA and DC electrical conductivity studies of phthaloeyanine and its complexes显示文摘 | SEOUDI R EI-BAHY G S El SAYED Z A | 2005 | J Mol Struct2005，753，： | 1 |
| 9 | Limonoids from Citrus reticulate显示文摘 | KHALILA A T MAATOOQ G T El SAYED K A | 2003 | Z Naturforsch2003，58，34： | 1 |
| 10 | Simultaneous determination of phosphate and silicate by first - deriva- tive spectrophotometry显示文摘 | El - SAYED A Y HUSSEIN Y Z MOHAMMED M A | 2001 | Analyst2001，10，126： | 1 |
| 11 | Limonoids from citrus reticulata显示文摘 | Ashraf T Khalil Galal T Maatooq Khalid A El Sayed | 2002 | Natarforsch2002，58，3： | 1 |
| 12 | Hyperspectral imaging for nondestructive determination of some quality attributes for strawberry显示文摘 | El MASRY G WANG N El SAYED A | 2007 | Journal of Food Engineering2007，81，： | 1 |
| 13 | A new norcembranoid dimer from the red sea soft coral Sinularia gardineri显示文摘 | El Sayed Mark T Hamann | 1996 | J Nat Prod1996，59，： | 1 |
| 14 | Blood Coagulation and Fibrinolysis at Rest and in Response to Maximal Exercise Before and After a Physical Comditioning Programme显示文摘 | EL SAYED M S LIN X RATTR A J | 1995 | Blood Coagul Fibrinolysis1995，6，8： | 1 |
| 15 | Growth of hydrocarbonutilizing isolated in chemically defined media显示文摘 | Haiim A EL - Sayed M M Mahmond W M Davis E M Conghlin R W | 1996 | International Biodeterioration & Biodegradation1996，37，12： | 1 |
| 16 | Self -assembly of platinum nanoparticles of various size and shape显示文摘 | Petroski J M Green T C E El - Sayed M A | 2001 | J Phys Chem A2001，105，： | 1 |
| 17 | Establishment and characterization of insect cell lines from 10 lepidopteran species显示文摘 | Goodman C L El Sayed G N Mclntosh A H | 2001 | In Vitro Cell Dev Biol Anim2001，37，6： | 1 |
| 18 | Treatment of mammary and extramammary Paget's skin disease with topical imiquimod显示文摘 | Mirer E El Sayed F Ammoury A | 2006 | J Dermatolog Treat2006，17，3： | 1 |
| 19 | Marine natural products as antituberculosis agents显示文摘 | El Sayed K A Bartyzel P Shen X Y | 2000 | Tetrahedron2000，56，7： | 1 |
| 20 | Controlling chitosan molecular weight via bio-chitosanolysis显示文摘 | Abd-Elmohdy F A El Sayed Z E Essam S | 2010 | Carbohydr Polym2010，82，3： | 1 |
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